Click here to switch to the map view.

The map label for this gene is rnc [H]

Identifier: 150009420

GI number: 150009420

Start: 3371968

End: 3372810

Strand: Direct

Name: rnc [H]

Synonym: BDI_2828

Alternate gene names: 150009420

Gene position: 3371968-3372810 (Clockwise)

Preceding gene: 150009419

Following gene: 150009421

Centisome position: 70.08

GC content: 41.16

Gene sequence:

>843_bases
GTGTTTAGAAAGCTATACAAACAGCTACATAAAAGAATAAGGCTCCTGCATAATAAAGGTAGGGAGCCTTATTTGTCTTT
ATCAAAGATTCTAGGTTTTTATCCGGATAATCTCCAGATTTACGAGCAGGCCTTGTTGCATAAATCATCATCGGTAGAGA
CGGGTGATGGTAAATGGCTTAACAATGAGCGTCTTGAATTTTTAGGAGATGGAATTTTGGATGCGGCGGTCGCCGATATT
GTCTATAAGCGCTACCCAAATAAGCGGGAAGGCTTTTTGACAAACACACGCTCCAAGATCGTACAACGGGAAACGATGAA
TAAGGTCGCCGTACAACTCGGCCTCGATCAAATGGTAGTCTATTCAACCAAGATAAACTCTCATAACAATCATATGTATG
GTAATGCGCTCGAGGCTTTGATCGGCGCTATTTATCTGGATCAAGGTTATGACGTTTGTTATAAGTTTATCCGTGACGTG
ATGATAGAAAAGTATATCGATGTAGATATGCTCGTCCGGAAAGAGATAAATTTCAAGTCAAACTTGATTGAATGGAGCCA
AAAGAACAAAATATCGATCTCGTTCGATCTAATAGAGTCTTTTACGGATCATGATGGGAATCCTGTATTCCAAAGCGCGA
TTAAATTGCTGGGCGAGCAAATTGGCATAGGTATCGGTTACTCCAAAAAAGAATCCCAGCAAGCGGCTTCTAAAATGGCG
GTCAAAAGATTGCGGACAGACAAAGAACTCCAGCAACGTATCTCTGCCACAAAGAAAAAGAAGGCTGGTGAACTAACCGA
TGAAAAAGAGTTTTCTGACCTCCCAGAGGAAGAAACTGTATGA

Upstream 100 bases:

>100_bases
AATAAGGCTCAAAAGAGAGAAGTGAAAGCCGCTTTATCGAATACGTTTGGTTTCGGTGGACACAACGCTTGCGCCATTGT
TAAAAAATTCGTGAAATAAC

Downstream 100 bases:

>100_bases
TAAACAGCAGAACTTGGGTAAATCGTTTGATATACCCAAGTTCTTCGTTATATTAAGAATAAGCTCATATAAAGTTGTAT
GTATGAAAAACCAGTACAGT

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MFRKLYKQLHKRIRLLHNKGREPYLSLSKILGFYPDNLQIYEQALLHKSSSVETGDGKWLNNERLEFLGDGILDAAVADI
VYKRYPNKREGFLTNTRSKIVQRETMNKVAVQLGLDQMVVYSTKINSHNNHMYGNALEALIGAIYLDQGYDVCYKFIRDV
MIEKYIDVDMLVRKEINFKSNLIEWSQKNKISISFDLIESFTDHDGNPVFQSAIKLLGEQIGIGIGYSKKESQQAASKMA
VKRLRTDKELQQRISATKKKKAGELTDEKEFSDLPEEETV

Sequences:

>Translated_280_residues
MFRKLYKQLHKRIRLLHNKGREPYLSLSKILGFYPDNLQIYEQALLHKSSSVETGDGKWLNNERLEFLGDGILDAAVADI
VYKRYPNKREGFLTNTRSKIVQRETMNKVAVQLGLDQMVVYSTKINSHNNHMYGNALEALIGAIYLDQGYDVCYKFIRDV
MIEKYIDVDMLVRKEINFKSNLIEWSQKNKISISFDLIESFTDHDGNPVFQSAIKLLGEQIGIGIGYSKKESQQAASKMA
VKRLRTDKELQQRISATKKKKAGELTDEKEFSDLPEEETV
>Mature_280_residues
MFRKLYKQLHKRIRLLHNKGREPYLSLSKILGFYPDNLQIYEQALLHKSSSVETGDGKWLNNERLEFLGDGILDAAVADI
VYKRYPNKREGFLTNTRSKIVQRETMNKVAVQLGLDQMVVYSTKINSHNNHMYGNALEALIGAIYLDQGYDVCYKFIRDV
MIEKYIDVDMLVRKEINFKSNLIEWSQKNKISISFDLIESFTDHDGNPVFQSAIKLLGEQIGIGIGYSKKESQQAASKMA
VKRLRTDKELQQRISATKKKKAGELTDEKEFSDLPEEETV

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Escherichia coli, GI1788920, Length=224, Percent_Identity=27.2321428571429, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17506883, Length=167, Percent_Identity=28.7425149700599, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193202651, Length=167, Percent_Identity=28.7425149700599, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17137682, Length=221, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 32279; Mature: 32279

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRKLYKQLHKRIRLLHNKGREPYLSLSKILGFYPDNLQIYEQALLHKSSSVETGDGKWL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
NNERLEFLGDGILDAAVADIVYKRYPNKREGFLTNTRSKIVQRETMNKVAVQLGLDQMVV
CCCHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHEE
YSTKINSHNNHMYGNALEALIGAIYLDQGYDVCYKFIRDVMIEKYIDVDMLVRKEINFKS
EEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHH
NLIEWSQKNKISISFDLIESFTDHDGNPVFQSAIKLLGEQIGIGIGYSKKESQQAASKMA
HHHHHCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VKRLRTDKELQQRISATKKKKAGELTDEKEFSDLPEEETV
HHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MFRKLYKQLHKRIRLLHNKGREPYLSLSKILGFYPDNLQIYEQALLHKSSSVETGDGKWL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
NNERLEFLGDGILDAAVADIVYKRYPNKREGFLTNTRSKIVQRETMNKVAVQLGLDQMVV
CCCHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHEE
YSTKINSHNNHMYGNALEALIGAIYLDQGYDVCYKFIRDVMIEKYIDVDMLVRKEINFKS
EEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHH
NLIEWSQKNKISISFDLIESFTDHDGNPVFQSAIKLLGEQIGIGIGYSKKESQQAASKMA
HHHHHCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VKRLRTDKELQQRISATKKKKAGELTDEKEFSDLPEEETV
HHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]