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The map label for this gene is engA

Identifier: 150009038

GI number: 150009038

Start: 2863369

End: 2864682

Strand: Reverse

Name: engA

Synonym: BDI_2434

Alternate gene names: 150009038

Gene position: 2864682-2863369 (Counterclockwise)

Preceding gene: 150009039

Following gene: 150009035

Centisome position: 59.54

GC content: 51.29

Gene sequence:

>1314_bases
ATGGGAAATATAGTAGCGATAGTGGGGAGACCCAATGTAGGTAAGTCAACCCTTTTCAACCGGTTGACGGGTACCCGTCA
GGCGATCGTGAACGAGGAGGCTGGTACTACCCGCGACCGTCAGTACGGCAAGGTGGAGTGGACCGGCAAGGAGTTTTCGC
TGATTGACACAGGCGGATGGGTGGTTAACTCGGAGGATGTTTTCGAGGAGGAGATCAACAAGCAGGTAAAAGTGGCTATC
GAGGAGGCGGACGTGATCTTGTTCGTCGTCGATGTATTGAATGGCATCACGGATCTGGACATGGAGGTGGCGCAGATCTT
GCGTCGTTGCAAGCGGCCGGTGATCGTGGTGGCGAACAAGGCGGATAATTATGATCTGCATCCGGCCTCGGCGGAGTTTT
ACTCGTTTGGCTTGGGAGAGCCTTTCTGCATCTCGGCCATCAATGGTTCTTATACCGGGGATTTGCTGGATAAGATCGTG
GCGACGTTGCCCGAGGAGAAGGTGGAGATACTGGAGGAGGAGTTGCCCCGTATCGCGATTATAGGACGCCCGAACGCGGG
AAAATCTTCTCTTATCAATGCTTTTATTGGCGAGGATCGTCATATCGTTACCGATATCGCAGGCACGACCCGTGATTCCA
TCTACACGAAATATAATAAATTCGGCTTGAACTTCTATTTGGTGGATACGGCGGGTATCCGTAAGAAGGGGAAGGTGAAT
GAGGACTTGGAGTATTACTCGGTGATCCGTTCGATCCGCACCATCGAGAACTCGGATGTCTGCGTGCTGATGTTGGACGC
TACGAGGGGTATCGAGAGCCAGGATATGAATATCTTCTCGCTGGTGCAGAAGAATAAGAAGGGATTGGTGGTTTGTGTGA
ATAAGTGGGACTTGATCGAAGATAAGAGCCAGAAGGTGATCGACTCGTATACGACCGCTATCCGCGAGCGTCTGGCTCCG
TTTACCGACTTCCCGATCTTGTTTATCTCCGCTCTGACGAAACAACGTATCCTGAAGGTGCTGGAGACCGCCAAGGAGGT
TTACGAGAATCGCTCCAAGCGTGTCCCTACGGCCAAGCTGAACGAGGTGATGCTTCCGATCATCGAGAATTATCCTCCCC
CAGCATGGAAGGGTAAGTATATCAAGATCAAATATATCACCCAGCTCCCGGCGGGCAGCGTGCCTTCTTTCGTGTTCTTC
TGTAACTTGCCGCAATGGATCAAGGACCCGTACAAACGTTTCCTTGAGAACAAGATCCGCGAGAACTGGGATTTTACCGG
TACGCCGATTAATATATTTATCCGGGAAAAGTAA

Upstream 100 bases:

>100_bases
AATGTTTGTCAAAGTGGAAAAAGACTGGCGTAACCGTGACAACATATTGAAGAACTTCGGTTATCAGCTGGACTAATAAT
AGCATACGAAAGGAGAATTT

Downstream 100 bases:

>100_bases
ATACTAGATACAAAAAAGCCGCTTCCTGTAACGGGGAGGCGGCTTTTTCTATTTAGAATAGGTCGGAATGCGTTCCGATA
TCGGTGAAAAGCAAGATTAG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MGNIVAIVGRPNVGKSTLFNRLTGTRQAIVNEEAGTTRDRQYGKVEWTGKEFSLIDTGGWVVNSEDVFEEEINKQVKVAI
EEADVILFVVDVLNGITDLDMEVAQILRRCKRPVIVVANKADNYDLHPASAEFYSFGLGEPFCISAINGSYTGDLLDKIV
ATLPEEKVEILEEELPRIAIIGRPNAGKSSLINAFIGEDRHIVTDIAGTTRDSIYTKYNKFGLNFYLVDTAGIRKKGKVN
EDLEYYSVIRSIRTIENSDVCVLMLDATRGIESQDMNIFSLVQKNKKGLVVCVNKWDLIEDKSQKVIDSYTTAIRERLAP
FTDFPILFISALTKQRILKVLETAKEVYENRSKRVPTAKLNEVMLPIIENYPPPAWKGKYIKIKYITQLPAGSVPSFVFF
CNLPQWIKDPYKRFLENKIRENWDFTGTPINIFIREK

Sequences:

>Translated_437_residues
MGNIVAIVGRPNVGKSTLFNRLTGTRQAIVNEEAGTTRDRQYGKVEWTGKEFSLIDTGGWVVNSEDVFEEEINKQVKVAI
EEADVILFVVDVLNGITDLDMEVAQILRRCKRPVIVVANKADNYDLHPASAEFYSFGLGEPFCISAINGSYTGDLLDKIV
ATLPEEKVEILEEELPRIAIIGRPNAGKSSLINAFIGEDRHIVTDIAGTTRDSIYTKYNKFGLNFYLVDTAGIRKKGKVN
EDLEYYSVIRSIRTIENSDVCVLMLDATRGIESQDMNIFSLVQKNKKGLVVCVNKWDLIEDKSQKVIDSYTTAIRERLAP
FTDFPILFISALTKQRILKVLETAKEVYENRSKRVPTAKLNEVMLPIIENYPPPAWKGKYIKIKYITQLPAGSVPSFVFF
CNLPQWIKDPYKRFLENKIRENWDFTGTPINIFIREK
>Mature_436_residues
GNIVAIVGRPNVGKSTLFNRLTGTRQAIVNEEAGTTRDRQYGKVEWTGKEFSLIDTGGWVVNSEDVFEEEINKQVKVAIE
EADVILFVVDVLNGITDLDMEVAQILRRCKRPVIVVANKADNYDLHPASAEFYSFGLGEPFCISAINGSYTGDLLDKIVA
TLPEEKVEILEEELPRIAIIGRPNAGKSSLINAFIGEDRHIVTDIAGTTRDSIYTKYNKFGLNFYLVDTAGIRKKGKVNE
DLEYYSVIRSIRTIENSDVCVLMLDATRGIESQDMNIFSLVQKNKKGLVVCVNKWDLIEDKSQKVIDSYTTAIRERLAPF
TDFPILFISALTKQRILKVLETAKEVYENRSKRVPTAKLNEVMLPIIENYPPPAWKGKYIKIKYITQLPAGSVPSFVFFC
NLPQWIKDPYKRFLENKIRENWDFTGTPINIFIREK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=465, Percent_Identity=39.5698924731183, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI2367268, Length=117, Percent_Identity=38.4615384615385, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788919, Length=119, Percent_Identity=37.8151260504202, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17507259, Length=125, Percent_Identity=33.6, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=209, Percent_Identity=32.0574162679426, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_PARD8 (A6LEP5)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001303781.1
- ProteinModelPortal:   A6LEP5
- SMR:   A6LEP5
- STRING:   A6LEP5
- GeneID:   5307583
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_2434
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   PDIS435591:BDI_2434-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49539; Mature: 49407

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNIVAIVGRPNVGKSTLFNRLTGTRQAIVNEEAGTTRDRQYGKVEWTGKEFSLIDTGGW
CCCEEEEEECCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCEEEECCCEEEEEECCCE
VVNSEDVFEEEINKQVKVAIEEADVILFVVDVLNGITDLDMEVAQILRRCKRPVIVVANK
EECCHHHHHHHCCCEEEEEEECCCEEEEHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEC
ADNYDLHPASAEFYSFGLGEPFCISAINGSYTGDLLDKIVATLPEEKVEILEEELPRIAI
CCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEEE
IGRPNAGKSSLINAFIGEDRHIVTDIAGTTRDSIYTKYNKFGLNFYLVDTAGIRKKGKVN
EECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCC
EDLEYYSVIRSIRTIENSDVCVLMLDATRGIESQDMNIFSLVQKNKKGLVVCVNKWDLIE
CCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCC
DKSQKVIDSYTTAIRERLAPFTDFPILFISALTKQRILKVLETAKEVYENRSKRVPTAKL
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
NEVMLPIIENYPPPAWKGKYIKIKYITQLPAGSVPSFVFFCNLPQWIKDPYKRFLENKIR
HHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
ENWDFTGTPINIFIREK
CCCCCCCCCEEEEEECC
>Mature Secondary Structure 
GNIVAIVGRPNVGKSTLFNRLTGTRQAIVNEEAGTTRDRQYGKVEWTGKEFSLIDTGGW
CCEEEEEECCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCEEEECCCEEEEEECCCE
VVNSEDVFEEEINKQVKVAIEEADVILFVVDVLNGITDLDMEVAQILRRCKRPVIVVANK
EECCHHHHHHHCCCEEEEEEECCCEEEEHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEC
ADNYDLHPASAEFYSFGLGEPFCISAINGSYTGDLLDKIVATLPEEKVEILEEELPRIAI
CCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEEE
IGRPNAGKSSLINAFIGEDRHIVTDIAGTTRDSIYTKYNKFGLNFYLVDTAGIRKKGKVN
EECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCC
EDLEYYSVIRSIRTIENSDVCVLMLDATRGIESQDMNIFSLVQKNKKGLVVCVNKWDLIE
CCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCC
DKSQKVIDSYTTAIRERLAPFTDFPILFISALTKQRILKVLETAKEVYENRSKRVPTAKL
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
NEVMLPIIENYPPPAWKGKYIKIKYITQLPAGSVPSFVFFCNLPQWIKDPYKRFLENKIR
HHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
ENWDFTGTPINIFIREK
CCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA