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The map label for this gene is rcsC [H]

Identifier: 150008868

GI number: 150008868

Start: 2649304

End: 2650779

Strand: Direct

Name: rcsC [H]

Synonym: BDI_2258

Alternate gene names: 150008868

Gene position: 2649304-2650779 (Clockwise)

Preceding gene: 150008867

Following gene: 150008869

Centisome position: 55.06

GC content: 42.75

Gene sequence:

>1476_bases
ATGTCAACAGTAATAGATTCAAATATTTTCAACACTTTAGTTTCAAATACATTCTATTCCTGTCCTTTAGGAGGGGCTAT
CTATGATACGGAAGGAAATCTGATAGACTTGAATAAGGCGATGTTCGCTCATTTTTCCTTGGCGGATAAGCATGACTTTA
TTATAGAACATCTATTTAATAACATCGTACTAACCGATTCCTTGAAGTCATCTTTAAGAAAAGGTGACGCAATTATATGC
GAAGAGCCCGTCACGTTTAAAGTAGAACCCATCTATACCGATGAACAGGGGCTTAGCGGGTATACGCTTTGGCTTACGCA
GCAGGGAGAAAAAGAAACTGACAGGGAAAATAAACTATTGATGGGACAATTGAACGAGAGCCGGATATTGATGCGGCAAG
CGTTGGAAGACGGTAAATTAGCCGCTTACTCATTCAGCTTCGACCGTTTCTCCACTTGCGACAAAAGGCATTGTAACCGC
TGTTTTCAATTCTACGGCACGACCAATACTCTATTAGATAAAAACAGGTTTATATGCAGGGCTTTATCATCCGTACGTAA
GCCCGAGGATAGTTTGGATTTCTTCTATCTGTTCAATAAAATCCGGGACGAGAAATTATCGTCTCACAACGTCACCTTCC
ACCTGAGGAATCAAGACGGGACTTATAAGATGTATGAAATATCGGGTAAAAGCATGGATATTGATGAAAGCGGCACCCCA
CATGTCATTATAGGTAGCATTATCGAAAAGGAAAACGACGAGCTAGCTATCGCAGATCATCAGAAATCCAAGGATCTTTC
CCTATTGAAATCTACGTTTCTGGCAAATATGACGCACGAGATCCGGACTCCGCTAAATGCCATCGTCGGCTTCTCCGATA
TGTTAGGACTGGAAGATGATCCGGAAATGCGTGAACAGTATATTTCCATGATTAAAGAAAATAACACGGCTTTGCTCGAA
TTAATCAATGACACGCTCGAGATGTCCAGAATCGAGTCCAATACGATCAATTGGTCATATGAGGATGTAAATCCGCTCGC
TATCATGCACGATGTATACGAATACGCCTCTCCCCGCATATCCAAAAACGTACGGTTAATCTTGGATGATTCTCCAAACG
TATCTCTTCACACGGATAAACATAAGCTTATGCTTATCTTGAAAAAACTACTTTCTAACGCCCTCCGATATACGGAGAAA
GGAGAAATTCATTTCGGATACCAATCGTTGTATCCGGTCAGCGTGCAATTTTACGTGTCCGATACAGGTAACGGCATCCC
GAAGGACAAACTGGGACATATCTTCGAACGATTCGTGCAATTGAACGAATTCCAGCCGGGCACCGGGTTAGGGCTTTCGA
TCTGTAAAGGTCTGGTCACCGCCATGGGAGGTACCATCTGGGTGAACTCGGAGGAAGGGAAAGGTTCTACCTTCAGTTTC
AAACTACCCATAACACCTCCGGATACGATCTCTTAA

Upstream 100 bases:

>100_bases
TAACGACTTATAAATACATCATAGAAGGAGACGGGCAGACGAGAATATAGGAACTCGCCTGTCTCTTTCTTCTTGAACAA
CACTTAAATCTAAACGAATA

Downstream 100 bases:

>100_bases
ACAATTCCTTGGTCTTTCTAAAGGATAATTGACAAGTAGTCATTATCTTTGCCTTTAACAAAATATTATTGTAACAGATA
TGAGACATTTCACTTGCGTA

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSTVIDSNIFNTLVSNTFYSCPLGGAIYDTEGNLIDLNKAMFAHFSLADKHDFIIEHLFNNIVLTDSLKSSLRKGDAIIC
EEPVTFKVEPIYTDEQGLSGYTLWLTQQGEKETDRENKLLMGQLNESRILMRQALEDGKLAAYSFSFDRFSTCDKRHCNR
CFQFYGTTNTLLDKNRFICRALSSVRKPEDSLDFFYLFNKIRDEKLSSHNVTFHLRNQDGTYKMYEISGKSMDIDESGTP
HVIIGSIIEKENDELAIADHQKSKDLSLLKSTFLANMTHEIRTPLNAIVGFSDMLGLEDDPEMREQYISMIKENNTALLE
LINDTLEMSRIESNTINWSYEDVNPLAIMHDVYEYASPRISKNVRLILDDSPNVSLHTDKHKLMLILKKLLSNALRYTEK
GEIHFGYQSLYPVSVQFYVSDTGNGIPKDKLGHIFERFVQLNEFQPGTGLGLSICKGLVTAMGGTIWVNSEEGKGSTFSF
KLPITPPDTIS

Sequences:

>Translated_491_residues
MSTVIDSNIFNTLVSNTFYSCPLGGAIYDTEGNLIDLNKAMFAHFSLADKHDFIIEHLFNNIVLTDSLKSSLRKGDAIIC
EEPVTFKVEPIYTDEQGLSGYTLWLTQQGEKETDRENKLLMGQLNESRILMRQALEDGKLAAYSFSFDRFSTCDKRHCNR
CFQFYGTTNTLLDKNRFICRALSSVRKPEDSLDFFYLFNKIRDEKLSSHNVTFHLRNQDGTYKMYEISGKSMDIDESGTP
HVIIGSIIEKENDELAIADHQKSKDLSLLKSTFLANMTHEIRTPLNAIVGFSDMLGLEDDPEMREQYISMIKENNTALLE
LINDTLEMSRIESNTINWSYEDVNPLAIMHDVYEYASPRISKNVRLILDDSPNVSLHTDKHKLMLILKKLLSNALRYTEK
GEIHFGYQSLYPVSVQFYVSDTGNGIPKDKLGHIFERFVQLNEFQPGTGLGLSICKGLVTAMGGTIWVNSEEGKGSTFSF
KLPITPPDTIS
>Mature_490_residues
STVIDSNIFNTLVSNTFYSCPLGGAIYDTEGNLIDLNKAMFAHFSLADKHDFIIEHLFNNIVLTDSLKSSLRKGDAIICE
EPVTFKVEPIYTDEQGLSGYTLWLTQQGEKETDRENKLLMGQLNESRILMRQALEDGKLAAYSFSFDRFSTCDKRHCNRC
FQFYGTTNTLLDKNRFICRALSSVRKPEDSLDFFYLFNKIRDEKLSSHNVTFHLRNQDGTYKMYEISGKSMDIDESGTPH
VIIGSIIEKENDELAIADHQKSKDLSLLKSTFLANMTHEIRTPLNAIVGFSDMLGLEDDPEMREQYISMIKENNTALLEL
INDTLEMSRIESNTINWSYEDVNPLAIMHDVYEYASPRISKNVRLILDDSPNVSLHTDKHKLMLILKKLLSNALRYTEKG
EIHFGYQSLYPVSVQFYVSDTGNGIPKDKLGHIFERFVQLNEFQPGTGLGLSICKGLVTAMGGTIWVNSEEGKGSTFSFK
LPITPPDTIS

Specific function: Member of the two-component regulatory system rcsC/rcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with rcsF, rcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=34.6774193548387, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=36.4, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI48994928, Length=297, Percent_Identity=31.6498316498317, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1789149, Length=250, Percent_Identity=34, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788713, Length=233, Percent_Identity=30.0429184549356, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=29.2792792792793, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=28.2511210762332, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788393, Length=225, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=30.4166666666667, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788549, Length=216, Percent_Identity=26.3888888888889, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=26.4069264069264, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=28.6324786324786, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=245, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790861, Length=214, Percent_Identity=27.5700934579439, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55751; Mature: 55620

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVIDSNIFNTLVSNTFYSCPLGGAIYDTEGNLIDLNKAMFAHFSLADKHDFIIEHLFN
CCCCCCHHHHHHHHHCCEECCCCCCEEECCCCCEEECCHHHHHHHCCCCCHHHHHHHHHC
NIVLTDSLKSSLRKGDAIICEEPVTFKVEPIYTDEQGLSGYTLWLTQQGEKETDRENKLL
CEEEEHHHHHHHHCCCEEEECCCCEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCEE
MGQLNESRILMRQALEDGKLAAYSFSFDRFSTCDKRHCNRCFQFYGTTNTLLDKNRFICR
EECCCHHHHHHHHHHCCCCEEEEEECCHHHCCHHHHHHHHHHHHHCCCHHHHCCCHHHHH
ALSSVRKPEDSLDFFYLFNKIRDEKLSSHNVTFHLRNQDGTYKMYEISGKSMDIDESGTP
HHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCEECCCCCCCC
HVIIGSIIEKENDELAIADHQKSKDLSLLKSTFLANMTHEIRTPLNAIVGFSDMLGLEDD
EEEEEHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHCCCCCC
PEMREQYISMIKENNTALLELINDTLEMSRIESNTINWSYEDVNPLAIMHDVYEYASPRI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCC
SKNVRLILDDSPNVSLHTDKHKLMLILKKLLSNALRYTEKGEIHFGYQSLYPVSVQFYVS
CCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEEEEE
DTGNGIPKDKLGHIFERFVQLNEFQPGTGLGLSICKGLVTAMGGTIWVNSEEGKGSTFSF
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEE
KLPITPPDTIS
EECCCCCCCCC
>Mature Secondary Structure 
STVIDSNIFNTLVSNTFYSCPLGGAIYDTEGNLIDLNKAMFAHFSLADKHDFIIEHLFN
CCCCCHHHHHHHHHCCEECCCCCCEEECCCCCEEECCHHHHHHHCCCCCHHHHHHHHHC
NIVLTDSLKSSLRKGDAIICEEPVTFKVEPIYTDEQGLSGYTLWLTQQGEKETDRENKLL
CEEEEHHHHHHHHCCCEEEECCCCEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCEE
MGQLNESRILMRQALEDGKLAAYSFSFDRFSTCDKRHCNRCFQFYGTTNTLLDKNRFICR
EECCCHHHHHHHHHHCCCCEEEEEECCHHHCCHHHHHHHHHHHHHCCCHHHHCCCHHHHH
ALSSVRKPEDSLDFFYLFNKIRDEKLSSHNVTFHLRNQDGTYKMYEISGKSMDIDESGTP
HHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCEECCCCCCCC
HVIIGSIIEKENDELAIADHQKSKDLSLLKSTFLANMTHEIRTPLNAIVGFSDMLGLEDD
EEEEEHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHCCCCCC
PEMREQYISMIKENNTALLELINDTLEMSRIESNTINWSYEDVNPLAIMHDVYEYASPRI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCC
SKNVRLILDDSPNVSLHTDKHKLMLILKKLLSNALRYTEKGEIHFGYQSLYPVSVQFYVS
CCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEEEEE
DTGNGIPKDKLGHIFERFVQLNEFQPGTGLGLSICKGLVTAMGGTIWVNSEEGKGSTFSF
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEE
KLPITPPDTIS
EECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504; 8626298 [H]