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The map label for this gene is ydeN [H]

Identifier: 150008689

GI number: 150008689

Start: 2461942

End: 2463300

Strand: Direct

Name: ydeN [H]

Synonym: BDI_2079

Alternate gene names: 150008689

Gene position: 2461942-2463300 (Clockwise)

Preceding gene: 150008688

Following gene: 150008690

Centisome position: 51.17

GC content: 38.48

Gene sequence:

>1359_bases
ATGAATAAAATTAAATATATACTGTACATTACAGGAGTTTTAGCCTCGTATGACGGGCATAGTCAACCGACAAAACCCAA
TATCATAGTTATCAATTGTGATGATATGGGATATGGAGACTTATCTTGTTTCGGAAGTCCTACGATAAAAACCCCGAATA
TCGACCGAATGGCTATAGAAGGACAAAAATGGAGTAGTTTTTACGTTTCAGCATCAGTCTCTTCTCCTAGCCGTGCCGGA
TTATTAACAGGCCGCCTAGGAGTCCGTACCGGAATGTATGGAGATCAACGCAGAGTCCTGTTTCCTGATTCCAAAGGGGG
ATTGCCTTCTGAGGAACTAACGATCGCTGAACTGCTGAAACAAGCCGGATATCATACGGCTTGCATAGGTAAATGGCATT
TAGGACATTTACCAGAATACATGCCATTACGTCACGGCTTTGACTATTTTTACGGTTATCCTTATTCCAATGATATGAGT
CGGAAGGAACAAATTAAATTAGGCAACACAAAATATCCTTATGAATATATTATTTATGAACAAGAAAAAGAACTGGAAAG
AGAGCCCCAACAATATAATTTAACGCAACAAGTGACGGAAGCTGCTATCCGCTACATTAAATCAAATGAGAATTCTCCTT
TTTTCTTGTATTTAGCACACCCTATGCCTCATATGCCTGTATATGCCTCTACTGACTTTCAAGGTAAATCAGCCAGAGGC
AAATATGGTGACACCGTAGAGGAACTGGATTGGAGTGTAGGACAAATCTTGCAAACATTAAAATCTGAAGGATTAGATAA
AAACACATTGGTTATTTTCACATCTGATAATGGGCCATGGCTTTTATGTAAACAAGAAGGAGGATCACCGGGTCCGTTAA
AGGATGGCAAAGCTTCCATGTTCGAAGGAGGGTTCCGCGTTCCATGTATTATGTGGGGAGCAATGGTTAAACCGGGATAT
ATAACGGATATGGCTAGTACATTAGACTTACTACCTACATTTTGTGAGATAGCAGGAATTCCATTGCCTTCAGATCGGCA
TTATGATGGAATCAGCTTGCTAAATGTATTAAAAGATAAGTCTACTTGTAAACGCGATGTGTTTTACTTTTATAGAGGCA
GTGAATTATATGCGATTCGAAAAGGTAAATATAAAGCCCATTTCTCTTATAGACCAGCTTATGGAACAACGGATAAAATC
ATATATGATAAACCTGTTTTATATGATTTAGGTACTGACCCTGGAGAATTATACAATATAGCAGAAGAACATCCGGATAT
TGTACAGGAATTAACCATGTTGGCCAATGCACATAAAGCTTCATTAAAGATTGCTAAGAGTATCTTCGACCAAAAGTAA

Upstream 100 bases:

>100_bases
GGATATGAGAATATCACTCATCAACTGGAAAAGGAGCTTATACGTTTACAAAAACAATATCAAGACACGAATGCCATGTC
GTTTAATAAACAATTAATCC

Downstream 100 bases:

>100_bases
ACTATATGTCTTATACTATTCGGTGAATTTGTTTCTCTTATTTTTCAAGAAGCAAATTCACTGATTTTATTTTTAGAGAG
AAAAGTCTTTTATAAAGTTT

Product: arylsulfatase A

Products: cerebroside; sulfate

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MNKIKYILYITGVLASYDGHSQPTKPNIIVINCDDMGYGDLSCFGSPTIKTPNIDRMAIEGQKWSSFYVSASVSSPSRAG
LLTGRLGVRTGMYGDQRRVLFPDSKGGLPSEELTIAELLKQAGYHTACIGKWHLGHLPEYMPLRHGFDYFYGYPYSNDMS
RKEQIKLGNTKYPYEYIIYEQEKELEREPQQYNLTQQVTEAAIRYIKSNENSPFFLYLAHPMPHMPVYASTDFQGKSARG
KYGDTVEELDWSVGQILQTLKSEGLDKNTLVIFTSDNGPWLLCKQEGGSPGPLKDGKASMFEGGFRVPCIMWGAMVKPGY
ITDMASTLDLLPTFCEIAGIPLPSDRHYDGISLLNVLKDKSTCKRDVFYFYRGSELYAIRKGKYKAHFSYRPAYGTTDKI
IYDKPVLYDLGTDPGELYNIAEEHPDIVQELTMLANAHKASLKIAKSIFDQK

Sequences:

>Translated_452_residues
MNKIKYILYITGVLASYDGHSQPTKPNIIVINCDDMGYGDLSCFGSPTIKTPNIDRMAIEGQKWSSFYVSASVSSPSRAG
LLTGRLGVRTGMYGDQRRVLFPDSKGGLPSEELTIAELLKQAGYHTACIGKWHLGHLPEYMPLRHGFDYFYGYPYSNDMS
RKEQIKLGNTKYPYEYIIYEQEKELEREPQQYNLTQQVTEAAIRYIKSNENSPFFLYLAHPMPHMPVYASTDFQGKSARG
KYGDTVEELDWSVGQILQTLKSEGLDKNTLVIFTSDNGPWLLCKQEGGSPGPLKDGKASMFEGGFRVPCIMWGAMVKPGY
ITDMASTLDLLPTFCEIAGIPLPSDRHYDGISLLNVLKDKSTCKRDVFYFYRGSELYAIRKGKYKAHFSYRPAYGTTDKI
IYDKPVLYDLGTDPGELYNIAEEHPDIVQELTMLANAHKASLKIAKSIFDQK
>Mature_452_residues
MNKIKYILYITGVLASYDGHSQPTKPNIIVINCDDMGYGDLSCFGSPTIKTPNIDRMAIEGQKWSSFYVSASVSSPSRAG
LLTGRLGVRTGMYGDQRRVLFPDSKGGLPSEELTIAELLKQAGYHTACIGKWHLGHLPEYMPLRHGFDYFYGYPYSNDMS
RKEQIKLGNTKYPYEYIIYEQEKELEREPQQYNLTQQVTEAAIRYIKSNENSPFFLYLAHPMPHMPVYASTDFQGKSARG
KYGDTVEELDWSVGQILQTLKSEGLDKNTLVIFTSDNGPWLLCKQEGGSPGPLKDGKASMFEGGFRVPCIMWGAMVKPGY
ITDMASTLDLLPTFCEIAGIPLPSDRHYDGISLLNVLKDKSTCKRDVFYFYRGSELYAIRKGKYKAHFSYRPAYGTTDKI
IYDKPVLYDLGTDPGELYNIAEEHPDIVQELTMLANAHKASLKIAKSIFDQK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=481, Percent_Identity=37.4220374220374, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI146229331, Length=430, Percent_Identity=39.3023255813954, Blast_Score=281, Evalue=6e-76,
Organism=Homo sapiens, GI146229329, Length=430, Percent_Identity=39.3023255813954, Blast_Score=281, Evalue=6e-76,
Organism=Homo sapiens, GI6005990, Length=430, Percent_Identity=39.3023255813954, Blast_Score=281, Evalue=6e-76,
Organism=Homo sapiens, GI146229324, Length=430, Percent_Identity=39.3023255813954, Blast_Score=281, Evalue=6e-76,
Organism=Homo sapiens, GI45430057, Length=441, Percent_Identity=34.4671201814059, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI58743319, Length=492, Percent_Identity=31.5040650406504, Blast_Score=208, Evalue=8e-54,
Organism=Homo sapiens, GI157266309, Length=501, Percent_Identity=31.3373253493014, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI146229327, Length=357, Percent_Identity=36.4145658263305, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI31742482, Length=509, Percent_Identity=30.8447937131631, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI71852584, Length=489, Percent_Identity=30.2658486707566, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI38569405, Length=483, Percent_Identity=28.5714285714286, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI53831991, Length=263, Percent_Identity=38.4030418250951, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI38569407, Length=359, Percent_Identity=31.1977715877437, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI59797060, Length=470, Percent_Identity=27.6595744680851, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI109389362, Length=357, Percent_Identity=28.8515406162465, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI71852586, Length=142, Percent_Identity=45.7746478873239, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI39930577, Length=495, Percent_Identity=24.2424242424242, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI189571643, Length=402, Percent_Identity=24.8756218905473, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI189571641, Length=402, Percent_Identity=24.8756218905473, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI189571638, Length=402, Percent_Identity=24.8756218905473, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI189571636, Length=402, Percent_Identity=24.8756218905473, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081924, Length=402, Percent_Identity=30.3482587064677, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790233, Length=453, Percent_Identity=29.1390728476821, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1790112, Length=478, Percent_Identity=22.5941422594142, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115533416, Length=447, Percent_Identity=29.3064876957494, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17559078, Length=249, Percent_Identity=33.7349397590361, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI115533418, Length=424, Percent_Identity=28.5377358490566, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24666175, Length=371, Percent_Identity=33.9622641509434, Blast_Score=178, Evalue=8e-45,
Organism=Drosophila melanogaster, GI24666109, Length=414, Percent_Identity=32.8502415458937, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI281363223, Length=518, Percent_Identity=27.7992277992278, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI281366397, Length=427, Percent_Identity=31.8501170960187, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI281366395, Length=427, Percent_Identity=31.8501170960187, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24666163, Length=427, Percent_Identity=31.8501170960187, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI21356831, Length=441, Percent_Identity=25.1700680272109, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.8

Molecular weight: Translated: 50970; Mature: 50970

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIKYILYITGVLASYDGHSQPTKPNIIVINCDDMGYGDLSCFGSPTIKTPNIDRMAIE
CCCEEEEEEEEEHHHCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCEEEEC
GQKWSSFYVSASVSSPSRAGLLTGRLGVRTGMYGDQRRVLFPDSKGGLPSEELTIAELLK
CCCCCEEEEEEECCCCCCCCEEECCHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHH
QAGYHTACIGKWHLGHLPEYMPLRHGFDYFYGYPYSNDMSRKEQIKLGNTKYPYEYIIYE
HCCCCEEEEECCCCCCCCCCCHHHCCCHHHCCCCCCCCCCCHHHEEECCCCCCEEEEEEC
QEKELEREPQQYNLTQQVTEAAIRYIKSNENSPFFLYLAHPMPHMPVYASTDFQGKSARG
CHHHHHCCCHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCCCCCCC
KYGDTVEELDWSVGQILQTLKSEGLDKNTLVIFTSDNGPWLLCKQEGGSPGPLKDGKASM
CCCCCHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCHHH
FEGGFRVPCIMWGAMVKPGYITDMASTLDLLPTFCEIAGIPLPSDRHYDGISLLNVLKDK
HCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCH
STCKRDVFYFYRGSELYAIRKGKYKAHFSYRPAYGTTDKIIYDKPVLYDLGTDPGELYNI
HHHHHCEEEEEECCEEEEEECCCEEEEEEECCCCCCCCCEEECCCEEEECCCCHHHHHHH
AEEHPDIVQELTMLANAHKASLKIAKSIFDQK
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKIKYILYITGVLASYDGHSQPTKPNIIVINCDDMGYGDLSCFGSPTIKTPNIDRMAIE
CCCEEEEEEEEEHHHCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCEEEEC
GQKWSSFYVSASVSSPSRAGLLTGRLGVRTGMYGDQRRVLFPDSKGGLPSEELTIAELLK
CCCCCEEEEEEECCCCCCCCEEECCHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHH
QAGYHTACIGKWHLGHLPEYMPLRHGFDYFYGYPYSNDMSRKEQIKLGNTKYPYEYIIYE
HCCCCEEEEECCCCCCCCCCCHHHCCCHHHCCCCCCCCCCCHHHEEECCCCCCEEEEEEC
QEKELEREPQQYNLTQQVTEAAIRYIKSNENSPFFLYLAHPMPHMPVYASTDFQGKSARG
CHHHHHCCCHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCCCCCCC
KYGDTVEELDWSVGQILQTLKSEGLDKNTLVIFTSDNGPWLLCKQEGGSPGPLKDGKASM
CCCCCHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCHHH
FEGGFRVPCIMWGAMVKPGYITDMASTLDLLPTFCEIAGIPLPSDRHYDGISLLNVLKDK
HCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCH
STCKRDVFYFYRGSELYAIRKGKYKAHFSYRPAYGTTDKIIYDKPVLYDLGTDPGELYNI
HHHHHCEEEEEECCEEEEEECCCEEEEEEECCCCCCCCCEEECCCEEEECCCCHHHHHHH
AEEHPDIVQELTMLANAHKASLKIAKSIFDQK
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cerebroside 3-sulfate; H2O

Specific reaction: A cerebroside 3-sulfate + H2O = a cerebroside + sulfate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]