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The map label for this gene is atsA [H]

Identifier: 150008688

GI number: 150008688

Start: 2460366

End: 2461949

Strand: Direct

Name: atsA [H]

Synonym: BDI_2078

Alternate gene names: 150008688

Gene position: 2460366-2461949 (Clockwise)

Preceding gene: 150008687

Following gene: 150008689

Centisome position: 51.14

GC content: 37.5

Gene sequence:

>1584_bases
ATGAAAAAAGAATTATTATTCACATTCTCTGCTTTAATAGCTACGACTTCCTGCAACATCAAAAAAACAGATTCAGAGCA
GATAGCAGGAAAAAAGCCGATGAATATCATCTATATCATGTCTGACGATCATTCTTACCAGACAATCAGTGCTTATGATA
AACGCTTCATACAAACTCCCAATATAGACCGACTGGCAAACGAGGGAGTACGTTTTACCAATAGCTTTGTTGCCAATTCC
ATCAGTGGACCTAGTCGAGCCTGTATATTAACCGGTAAACATAGTCATGCTAATGGTTTCACTGATAACAGTTCCACATT
TGATGGTTCCCAGCAAACATACCCCAAACTTTTACAAAAAGCCGGATATGAAACAGCAATAATCGGAAAGTGGCATCTAA
CTTCCGCTCCTACCGGATTTGATTATTCGGAAATTTTAATAGGTCAAGGCATTTATTACAACGCTCCATTTATCAAAAAC
GGGAAACAGGTCCCATCAAAAGGCTATGTTACCAACGTCATCACAGAAAAAGCAATCGACTGGATGGAGAATATACATGA
TAAAAATAAGCCTTTCTGCTTGTTACTCCATCACAAAGCTCCTCATCGTACATGGATGCCCGATACTTGTGATTTACAAC
TTTTCAGCGATACGACGTTCGAGTTACCAGCCAATTTTTATGACGACTACAACGGTCGTCAAGCCGCTCATGAGCAAAAG
ATGAGTATCATAAAAGATATGGATTTAGTCTATGATTTAAAAATGGCTGATAAAGAAAATGAAATCCATACAACTACAGG
GTTAGAGAATGCCGGACGCAGCATGTATAACAGTATGACACCCGAAGAGAAAGCAGCTTGGGATGCTCATTATGATCCAA
TCATTCAGAAATTCAAGAAAGACAAACTTTCTGGTAAGCAACTATCTGAATGGAAATATCAACAATATATGCGAGACTAT
TTACGTGTCATCCATTCCATAGACAGAAATATTGGAGTATTATTGAATTATTTAGAAAAGACAGGATTATTAGAGAACAC
AATGATTGTCTACACTTCCGACCAAGGATTCTATATGGGAGAACACGGATGGTTCGATAAACGTTTCATGTATGAGGAAT
CTTTCCGGACTCCTTTATTAATTCGTTTGCCGGGAGGAAAGAAAGGAGATATCGATGAGTTTGTCCAAAACATTGATTAC
GGACCGACCATCCTAGATTTAGCAGGAATCCAAATCCCATCCGATATGCATGGTATTTCCTTTTTGCCTTTGTTACGTGG
AGAAAAAGTTGAGAACTGGCGTAAATCACTCTATTACCACTTTTATGAGTACCCTGCGGAGCATTCTGTTAAACGTCATT
ATGGCGTACGCACAGAACGTTATAAATTAATTCATTTTTATAACGATATCGATAAATGGGAATTATTTGATCTACAAGAA
GATCCTATGGAGATGAACAACTTGTATGGAAAAACAGGATATGAGAATATCACTCATCAACTGGAAAAGGAGCTTATACG
TTTACAAAAACAATATCAAGACACGAATGCCATGTCGTTTAATAAACAATTAATCCATGAATAA

Upstream 100 bases:

>100_bases
ATTTAGCCTAATAAAAGAGAAAGTCTTTCCTCACAAATTTTAGGCTAAAACCCTGTAACAAACAAATACCTTAATCACGA
ACACAATAAAAGTCTAAATA

Downstream 100 bases:

>100_bases
AATTAAATATATACTGTACATTACAGGAGTTTTAGCCTCGTATGACGGGCATAGTCAACCGACAAAACCCAATATCATAG
TTATCAATTGTGATGATATG

Product: putative sulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MKKELLFTFSALIATTSCNIKKTDSEQIAGKKPMNIIYIMSDDHSYQTISAYDKRFIQTPNIDRLANEGVRFTNSFVANS
ISGPSRACILTGKHSHANGFTDNSSTFDGSQQTYPKLLQKAGYETAIIGKWHLTSAPTGFDYSEILIGQGIYYNAPFIKN
GKQVPSKGYVTNVITEKAIDWMENIHDKNKPFCLLLHHKAPHRTWMPDTCDLQLFSDTTFELPANFYDDYNGRQAAHEQK
MSIIKDMDLVYDLKMADKENEIHTTTGLENAGRSMYNSMTPEEKAAWDAHYDPIIQKFKKDKLSGKQLSEWKYQQYMRDY
LRVIHSIDRNIGVLLNYLEKTGLLENTMIVYTSDQGFYMGEHGWFDKRFMYEESFRTPLLIRLPGGKKGDIDEFVQNIDY
GPTILDLAGIQIPSDMHGISFLPLLRGEKVENWRKSLYYHFYEYPAEHSVKRHYGVRTERYKLIHFYNDIDKWELFDLQE
DPMEMNNLYGKTGYENITHQLEKELIRLQKQYQDTNAMSFNKQLIHE

Sequences:

>Translated_527_residues
MKKELLFTFSALIATTSCNIKKTDSEQIAGKKPMNIIYIMSDDHSYQTISAYDKRFIQTPNIDRLANEGVRFTNSFVANS
ISGPSRACILTGKHSHANGFTDNSSTFDGSQQTYPKLLQKAGYETAIIGKWHLTSAPTGFDYSEILIGQGIYYNAPFIKN
GKQVPSKGYVTNVITEKAIDWMENIHDKNKPFCLLLHHKAPHRTWMPDTCDLQLFSDTTFELPANFYDDYNGRQAAHEQK
MSIIKDMDLVYDLKMADKENEIHTTTGLENAGRSMYNSMTPEEKAAWDAHYDPIIQKFKKDKLSGKQLSEWKYQQYMRDY
LRVIHSIDRNIGVLLNYLEKTGLLENTMIVYTSDQGFYMGEHGWFDKRFMYEESFRTPLLIRLPGGKKGDIDEFVQNIDY
GPTILDLAGIQIPSDMHGISFLPLLRGEKVENWRKSLYYHFYEYPAEHSVKRHYGVRTERYKLIHFYNDIDKWELFDLQE
DPMEMNNLYGKTGYENITHQLEKELIRLQKQYQDTNAMSFNKQLIHE
>Mature_527_residues
MKKELLFTFSALIATTSCNIKKTDSEQIAGKKPMNIIYIMSDDHSYQTISAYDKRFIQTPNIDRLANEGVRFTNSFVANS
ISGPSRACILTGKHSHANGFTDNSSTFDGSQQTYPKLLQKAGYETAIIGKWHLTSAPTGFDYSEILIGQGIYYNAPFIKN
GKQVPSKGYVTNVITEKAIDWMENIHDKNKPFCLLLHHKAPHRTWMPDTCDLQLFSDTTFELPANFYDDYNGRQAAHEQK
MSIIKDMDLVYDLKMADKENEIHTTTGLENAGRSMYNSMTPEEKAAWDAHYDPIIQKFKKDKLSGKQLSEWKYQQYMRDY
LRVIHSIDRNIGVLLNYLEKTGLLENTMIVYTSDQGFYMGEHGWFDKRFMYEESFRTPLLIRLPGGKKGDIDEFVQNIDY
GPTILDLAGIQIPSDMHGISFLPLLRGEKVENWRKSLYYHFYEYPAEHSVKRHYGVRTERYKLIHFYNDIDKWELFDLQE
DPMEMNNLYGKTGYENITHQLEKELIRLQKQYQDTNAMSFNKQLIHE

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI58743319, Length=465, Percent_Identity=23.4408602150538, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI39930577, Length=192, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI240255478, Length=117, Percent_Identity=41.8803418803419, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI240255483, Length=117, Percent_Identity=41.8803418803419, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI29789100, Length=117, Percent_Identity=41.8803418803419, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI189571643, Length=117, Percent_Identity=42.7350427350427, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI189571641, Length=117, Percent_Identity=42.7350427350427, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI189571638, Length=117, Percent_Identity=42.7350427350427, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI189571636, Length=117, Percent_Identity=42.7350427350427, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI4504061, Length=127, Percent_Identity=40.9448818897638, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI4503899, Length=132, Percent_Identity=37.1212121212121, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI53831991, Length=121, Percent_Identity=38.8429752066116, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI157266309, Length=157, Percent_Identity=32.484076433121, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI71852586, Length=161, Percent_Identity=32.9192546583851, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI71852584, Length=161, Percent_Identity=32.9192546583851, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI45430057, Length=190, Percent_Identity=32.1052631578947, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI31742482, Length=143, Percent_Identity=31.4685314685315, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI146229331, Length=114, Percent_Identity=35.0877192982456, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI146229329, Length=114, Percent_Identity=35.0877192982456, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI6005990, Length=114, Percent_Identity=35.0877192982456, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI146229324, Length=114, Percent_Identity=35.0877192982456, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI38569407, Length=206, Percent_Identity=28.6407766990291, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI4506919, Length=126, Percent_Identity=34.9206349206349, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI38569405, Length=206, Percent_Identity=28.6407766990291, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI59797060, Length=105, Percent_Identity=37.1428571428571, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI109389362, Length=135, Percent_Identity=35.5555555555556, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081924, Length=178, Percent_Identity=35.9550561797753, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1790112, Length=282, Percent_Identity=23.758865248227, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17568795, Length=413, Percent_Identity=26.3922518159806, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17559078, Length=135, Percent_Identity=31.8518518518519, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356831, Length=548, Percent_Identity=24.8175182481752, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24647401, Length=126, Percent_Identity=40.4761904761905, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281366397, Length=228, Percent_Identity=31.140350877193, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI281366395, Length=228, Percent_Identity=31.140350877193, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24666163, Length=228, Percent_Identity=31.140350877193, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24666109, Length=211, Percent_Identity=29.8578199052133, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922168, Length=131, Percent_Identity=38.1679389312977, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24653364, Length=131, Percent_Identity=38.1679389312977, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666175, Length=197, Percent_Identity=29.4416243654822, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363223, Length=197, Percent_Identity=27.9187817258883, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 61293; Mature: 61293

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00523 SULFATASE_1 ; PS00149 SULFATASE_2 ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKELLFTFSALIATTSCNIKKTDSEQIAGKKPMNIIYIMSDDHSYQTISAYDKRFIQTP
CCCHHHHHHHHHHHHCCCCCEECCHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCC
NIDRLANEGVRFTNSFVANSISGPSRACILTGKHSHANGFTDNSSTFDGSQQTYPKLLQK
CHHHHHHCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AGYETAIIGKWHLTSAPTGFDYSEILIGQGIYYNAPFIKNGKQVPSKGYVTNVITEKAID
CCCCEEEEEEEEECCCCCCCCHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
WMENIHDKNKPFCLLLHHKAPHRTWMPDTCDLQLFSDTTFELPANFYDDYNGRQAAHEQK
HHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCEECCCHHHCCCCCHHHHHHHH
MSIIKDMDLVYDLKMADKENEIHTTTGLENAGRSMYNSMTPEEKAAWDAHYDPIIQKFKK
HHHHHHHHHHEEEHHCCCCCCEEEECCCCHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHH
DKLSGKQLSEWKYQQYMRDYLRVIHSIDRNIGVLLNYLEKTGLLENTMIVYTSDQGFYMG
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCEECC
EHGWFDKRFMYEESFRTPLLIRLPGGKKGDIDEFVQNIDYGPTILDLAGIQIPSDMHGIS
CCCCCCHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCE
FLPLLRGEKVENWRKSLYYHFYEYPAEHSVKRHYGVRTERYKLIHFYNDIDKWELFDLQE
EEHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHEEEEEEECCCCCEEEECCCC
DPMEMNNLYGKTGYENITHQLEKELIRLQKQYQDTNAMSFNKQLIHE
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKKELLFTFSALIATTSCNIKKTDSEQIAGKKPMNIIYIMSDDHSYQTISAYDKRFIQTP
CCCHHHHHHHHHHHHCCCCCEECCHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCC
NIDRLANEGVRFTNSFVANSISGPSRACILTGKHSHANGFTDNSSTFDGSQQTYPKLLQK
CHHHHHHCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AGYETAIIGKWHLTSAPTGFDYSEILIGQGIYYNAPFIKNGKQVPSKGYVTNVITEKAID
CCCCEEEEEEEEECCCCCCCCHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
WMENIHDKNKPFCLLLHHKAPHRTWMPDTCDLQLFSDTTFELPANFYDDYNGRQAAHEQK
HHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCEECCCHHHCCCCCHHHHHHHH
MSIIKDMDLVYDLKMADKENEIHTTTGLENAGRSMYNSMTPEEKAAWDAHYDPIIQKFKK
HHHHHHHHHHEEEHHCCCCCCEEEECCCCHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHH
DKLSGKQLSEWKYQQYMRDYLRVIHSIDRNIGVLLNYLEKTGLLENTMIVYTSDQGFYMG
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCEECC
EHGWFDKRFMYEESFRTPLLIRLPGGKKGDIDEFVQNIDYGPTILDLAGIQIPSDMHGIS
CCCCCCHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCE
FLPLLRGEKVENWRKSLYYHFYEYPAEHSVKRHYGVRTERYKLIHFYNDIDKWELFDLQE
EEHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHEEEEEEECCCCCEEEECCCC
DPMEMNNLYGKTGYENITHQLEKELIRLQKQYQDTNAMSFNKQLIHE
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]