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The map label for this gene is pchA [H]

Identifier: 150007777

GI number: 150007777

Start: 1309884

End: 1310981

Strand: Direct

Name: pchA [H]

Synonym: BDI_1135

Alternate gene names: 150007777

Gene position: 1309884-1310981 (Clockwise)

Preceding gene: 150007776

Following gene: 150007778

Centisome position: 27.22

GC content: 49.18

Gene sequence:

>1098_bases
ATGATTCCAAGAGATTCTTACGAAATAATAGACACGTTGATCAAGCAAGGCCGGAGTTTCGCTATTTGGCGTATTCCCGG
TGAGGATAGGCTCCATTTCAGGATGCAAAGCGCCGGCTCTCCTTGCCTATTATACGACATAAAAGACTTAAATGAACGGA
GCGGTTTTGTAATCGCTCCGTTTCAGGTGACAGCGGAACGACCTATCGTTTTAATCCAACCGGATTGCTTTGAAATCCCC
TCCGAATCCGATTGGGATTTCTCTCGAGAGAAAAACGAATTCCCTTCGAATGAAATCGAAATCCCGTCCGAATCCGAGGA
GAAGGAACGATACGCTTACCATTTCTCCCTGTTTACCAGCCCTTTGCTAAAAGGAAGCCAAGATAAACTAGTCCTATCCC
GTAGCAAAACGATCCGGAAAGATCCCTCTTTCTCACCCGGCAAGGCATTCTTCGCCGCAGTAGAACGATATATCCGCTCC
TATGTCTACCTTTGCCATACCCCGGAAACCGGAACTTGGATGGGTGGGACACCGGAAATCTTGTTATCCGGCGAGAAAGG
CGACTGGCAAACGGTAGCTTTGGCCGGAACCCAATCCTTACGAGACGGGAAATTACCGAAAAGCTGGGACCATAAGAATT
GGAGAGAACAGCAATTAGTCGCCTCCTATATACGCCGCCAGCTGTCCACCTTGGGTATTACTCCCGAGGAGAAGGGGCCT
TATTCAGCCCGGGCCGGAGAGGTTTCCCATTTGAAAAGCGATTTCTTCTTCTCCTTGCCGAATCCCGAGAAGCTGGGTGA
TGTCCTTCAACTATTACACCCTACTCCAGCCGTTTGCGGTCTTCCCAAGGAGGAGGCTTATCATTTCATCATCGAGAATG
AGGGGTACGATCGTAGCTATTACTCCGGTTTCATCGGTTGGCTGGATCCCAAAGGCAAAACAGATCTGTACGTAAACCTC
CGTTGCATGAATATCCTCCCCCAAACCTTTACGCTGTATGCCGGAGGCGGTCTGTTGGCGGCCTCGCAGCTAGAGGATGA
GTGGCAGGAGACAGAGGATAAATTAGATACGATGCGGAGAATAGTGGGTAATTTATAA

Upstream 100 bases:

>100_bases
ACAAAGGCCGTTCATCCCATGTGTGGAACGTAGACATATTCACCTCTACCGACAAACTGGTTTCCTCGGTACGGGTAATC
AATAGCATACTAAAGAAGAA

Downstream 100 bases:

>100_bases
TTTTATATCATATAATGTATAGCGATAAAAAGAACATCCTTCAATTGGTAGCCTTGCTGATAGAGCACGGCGTAAGTAAT
ATCGTGCTATGTCCGGGGAG

Product: isochorismate synthase

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MIPRDSYEIIDTLIKQGRSFAIWRIPGEDRLHFRMQSAGSPCLLYDIKDLNERSGFVIAPFQVTAERPIVLIQPDCFEIP
SESDWDFSREKNEFPSNEIEIPSESEEKERYAYHFSLFTSPLLKGSQDKLVLSRSKTIRKDPSFSPGKAFFAAVERYIRS
YVYLCHTPETGTWMGGTPEILLSGEKGDWQTVALAGTQSLRDGKLPKSWDHKNWREQQLVASYIRRQLSTLGITPEEKGP
YSARAGEVSHLKSDFFFSLPNPEKLGDVLQLLHPTPAVCGLPKEEAYHFIIENEGYDRSYYSGFIGWLDPKGKTDLYVNL
RCMNILPQTFTLYAGGGLLAASQLEDEWQETEDKLDTMRRIVGNL

Sequences:

>Translated_365_residues
MIPRDSYEIIDTLIKQGRSFAIWRIPGEDRLHFRMQSAGSPCLLYDIKDLNERSGFVIAPFQVTAERPIVLIQPDCFEIP
SESDWDFSREKNEFPSNEIEIPSESEEKERYAYHFSLFTSPLLKGSQDKLVLSRSKTIRKDPSFSPGKAFFAAVERYIRS
YVYLCHTPETGTWMGGTPEILLSGEKGDWQTVALAGTQSLRDGKLPKSWDHKNWREQQLVASYIRRQLSTLGITPEEKGP
YSARAGEVSHLKSDFFFSLPNPEKLGDVLQLLHPTPAVCGLPKEEAYHFIIENEGYDRSYYSGFIGWLDPKGKTDLYVNL
RCMNILPQTFTLYAGGGLLAASQLEDEWQETEDKLDTMRRIVGNL
>Mature_365_residues
MIPRDSYEIIDTLIKQGRSFAIWRIPGEDRLHFRMQSAGSPCLLYDIKDLNERSGFVIAPFQVTAERPIVLIQPDCFEIP
SESDWDFSREKNEFPSNEIEIPSESEEKERYAYHFSLFTSPLLKGSQDKLVLSRSKTIRKDPSFSPGKAFFAAVERYIRS
YVYLCHTPETGTWMGGTPEILLSGEKGDWQTVALAGTQSLRDGKLPKSWDHKNWREQQLVASYIRRQLSTLGITPEEKGP
YSARAGEVSHLKSDFFFSLPNPEKLGDVLQLLHPTPAVCGLPKEEAYHFIIENEGYDRSYYSGFIGWLDPKGKTDLYVNL
RCMNILPQTFTLYAGGGLLAASQLEDEWQETEDKLDTMRRIVGNL

Specific function: Involved in the conversion of chorismate to salicylate (Probable) [H]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=313, Percent_Identity=28.1150159744409, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87082077, Length=265, Percent_Identity=29.811320754717, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788114, Length=209, Percent_Identity=27.7511961722488, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 41668; Mature: 41668

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPRDSYEIIDTLIKQGRSFAIWRIPGEDRLHFRMQSAGSPCLLYDIKDLNERSGFVIAP
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCCEEEEE
FQVTAERPIVLIQPDCFEIPSESDWDFSREKNEFPSNEIEIPSESEEKERYAYHFSLFTS
EEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHEEHHHHHHH
PLLKGSQDKLVLSRSKTIRKDPSFSPGKAFFAAVERYIRSYVYLCHTPETGTWMGGTPEI
HHHCCCCCCEEEECCCHHCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCE
LLSGEKGDWQTVALAGTQSLRDGKLPKSWDHKNWREQQLVASYIRRQLSTLGITPEEKGP
EEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
YSARAGEVSHLKSDFFFSLPNPEKLGDVLQLLHPTPAVCGLPKEEAYHFIIENEGYDRSY
CCCCCCCHHHHCCCCEEECCCHHHHHHHHHHHCCCCHHCCCCHHHCEEEEEECCCCCCHH
YSGFIGWLDPKGKTDLYVNLRCMNILPQTFTLYAGGGLLAASQLEDEWQETEDKLDTMRR
HCCEEEEECCCCCCEEEEEEEEEECCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHH
IVGNL
HHCCC
>Mature Secondary Structure
MIPRDSYEIIDTLIKQGRSFAIWRIPGEDRLHFRMQSAGSPCLLYDIKDLNERSGFVIAP
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCCEEEEE
FQVTAERPIVLIQPDCFEIPSESDWDFSREKNEFPSNEIEIPSESEEKERYAYHFSLFTS
EEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHEEHHHHHHH
PLLKGSQDKLVLSRSKTIRKDPSFSPGKAFFAAVERYIRSYVYLCHTPETGTWMGGTPEI
HHHCCCCCCEEEECCCHHCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCE
LLSGEKGDWQTVALAGTQSLRDGKLPKSWDHKNWREQQLVASYIRRQLSTLGITPEEKGP
EEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
YSARAGEVSHLKSDFFFSLPNPEKLGDVLQLLHPTPAVCGLPKEEAYHFIIENEGYDRSY
CCCCCCCHHHHCCCCEEECCCHHHHHHHHHHHCCCCHHCCCCHHHCEEEEEECCCCCCHH
YSGFIGWLDPKGKTDLYVNLRCMNILPQTFTLYAGGGLLAASQLEDEWQETEDKLDTMRR
HCCEEEEECCCCCCEEEEEEEEEECCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHH
IVGNL
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7500944; 10984043 [H]