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The map label for this gene is nuoG [C]

Identifier: 150007689

GI number: 150007689

Start: 1209806

End: 1211596

Strand: Direct

Name: nuoG [C]

Synonym: BDI_1044

Alternate gene names: 150007689

Gene position: 1209806-1211596 (Clockwise)

Preceding gene: 150007688

Following gene: 150007690

Centisome position: 25.14

GC content: 48.86

Gene sequence:

>1791_bases
ATGGAAACAATTCAATTAATCATAGATAATAAAGAGGTGGAAGTGCCGAGAGGAACCACCATTTTAGATGCGGCAAAAAG
TGTAGGTATCCACATCCCGACACTCTGTTATATGAAACTGGAGGACTTGCACTACGAGAATAATCCGGGAGCTTGCCGTA
TTTGTGTCGTAGAGATCGAGGGACGTAGAAATCTAGCCCCATCCTGTAAGATGGAATGTACGGAAGGCATGGTCGTACGG
ACACATACCCCCCGGGTGATGAATGCCCGTAGGACGGTGATGGAGCTGATCCTCTCGAATCATCCGGCGGAATGTCTGAC
ATGTAGCAGCAACGGACATTGCGAGTTACAAAAGATCGCACATGACTTAGGAATCCGTGAGATCCGGTATAAGGGAGAGA
TGTCCACATTTACGATAGACCGTTCCCCTTCCATTGTGCGGAACATGAACAAATGTATCATGTGCCGCCGCTGTGAGACC
ATGTGTAATACGATACAGACAGTTGGCGCCTTGACTGCCGTGAACCGTGGATTTAACGCGGCCGTATCGACTGCTTTTGA
ACGGGATATGGCCGGAAGTACCTGTTCGTATTGTGGACAATGCGTATCCGTCTGTCCTGTAAACGCGCTTAGCGGACGTA
ATACGCAACAGCCGGTCTTGGACGCTTTGGCCGATCCTACTAAAATTGTTATCGCCCAGACAGCGCCGGCGGTTCGCACA
GCGTTGGGACGTGATTTCGGGTATGAGCCGGGTACATTGGTTACAGGCAAGATGGTTTCAGCTTTGCGTCAATTGGGTTT
TGATTATGTATTCGATACGGACTTTGCCGCCGACTTGACCATTATGGAAGAGGGTACGGAATTATTACATCGCCTAGGTA
GTTACCTAAATGGAGACAAAGAGGTGAAAATACCGTTAATGACGAGTTGTTGTCCGGGTTGGGTTAGCTTTGTGGAACAA
CATTTCCCCGAGTTACGGGATAATTTATCTACAGCCAAGAGCCCGCAGCAAATGTTCGGAGCGATCGCCAAGAGTTATTT
CGCCGAGAAGTTGGGAGTGGACCGTAAGGATTTGGTAGTCGTATCTATCATGCCTTGTTTGGCGAAGAAGTATGAGGCTA
GCCGCCCGGAGTTTAGCGTGGAAGGTAATCCCGATGTAGATTATTCGATCTATACCCGTGAGTTAGCCCGTTTAATCCGT
TATGCGAATATAGATTTCAATGAACTGCCGGATGGTGAGTTCGATAGCCCGTTGGGTGAATCTACCGGAGCGAGCGTGAT
CTTCGGTACTACCGGCGGTGTTATCGAGGCCGCTTGCCGTACAGCTTATGAATTATATACGAAGAAAAATCTGGATAAAG
TGGACTTCGAGGAGTTACGCGGGCTGGAAGGTATTCGTAGCGCTACGATCGATTTTAATGGGACTCCGGTAAAGATCGGT
ATCGCTCATGGTCTGGGGAATGCCCGCAAATTGATCGAGGAGGTGAAGAACGGTACCTCTCCTTATCATGCGATCGAGGT
GATGGCTTGTCCGGGAGGCTGTATCGGCGGTGGTGGACAACCGTTCCACCGAGGCCGTATGGAGGTACTTCGCCGGCGTG
CTTCCGCTCTTTACCGGGAAGACGCTAACAAACCGCTTCGCAAGAGCCATGAGAATCCGTATATCCAGCAATTATACAGC
GAGTATTTGGGAGAGCCTTGCGGACCGAAAGCCCATAAATTACTGCATACCCATTACATAGATCGTAAGGAAGTAATCGG
TATGTATATAGAAACCGAAAAAAGTAAATAA

Upstream 100 bases:

>100_bases
TTCCTCATATTATCGATCCGCAAGCTTGTATCCGTTGCGGTACCTGTATGGAGAAGTGTAAGTTCGGAGCGATTTATGTC
CACTAAATTTATTTATAAGC

Downstream 100 bases:

>100_bases
GCCATGAATGAGATACATTTGCCTAAAACAAAAGTAGCGGAGCTACATGCGATATGCGCTGAACGCAACAACGATCCCGG
GGAGTTGATCAATATCTTGC

Product: NADH:ubiquinone oxidoreductase subunit

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
METIQLIIDNKEVEVPRGTTILDAAKSVGIHIPTLCYMKLEDLHYENNPGACRICVVEIEGRRNLAPSCKMECTEGMVVR
THTPRVMNARRTVMELILSNHPAECLTCSSNGHCELQKIAHDLGIREIRYKGEMSTFTIDRSPSIVRNMNKCIMCRRCET
MCNTIQTVGALTAVNRGFNAAVSTAFERDMAGSTCSYCGQCVSVCPVNALSGRNTQQPVLDALADPTKIVIAQTAPAVRT
ALGRDFGYEPGTLVTGKMVSALRQLGFDYVFDTDFAADLTIMEEGTELLHRLGSYLNGDKEVKIPLMTSCCPGWVSFVEQ
HFPELRDNLSTAKSPQQMFGAIAKSYFAEKLGVDRKDLVVVSIMPCLAKKYEASRPEFSVEGNPDVDYSIYTRELARLIR
YANIDFNELPDGEFDSPLGESTGASVIFGTTGGVIEAACRTAYELYTKKNLDKVDFEELRGLEGIRSATIDFNGTPVKIG
IAHGLGNARKLIEEVKNGTSPYHAIEVMACPGGCIGGGGQPFHRGRMEVLRRRASALYREDANKPLRKSHENPYIQQLYS
EYLGEPCGPKAHKLLHTHYIDRKEVIGMYIETEKSK

Sequences:

>Translated_596_residues
METIQLIIDNKEVEVPRGTTILDAAKSVGIHIPTLCYMKLEDLHYENNPGACRICVVEIEGRRNLAPSCKMECTEGMVVR
THTPRVMNARRTVMELILSNHPAECLTCSSNGHCELQKIAHDLGIREIRYKGEMSTFTIDRSPSIVRNMNKCIMCRRCET
MCNTIQTVGALTAVNRGFNAAVSTAFERDMAGSTCSYCGQCVSVCPVNALSGRNTQQPVLDALADPTKIVIAQTAPAVRT
ALGRDFGYEPGTLVTGKMVSALRQLGFDYVFDTDFAADLTIMEEGTELLHRLGSYLNGDKEVKIPLMTSCCPGWVSFVEQ
HFPELRDNLSTAKSPQQMFGAIAKSYFAEKLGVDRKDLVVVSIMPCLAKKYEASRPEFSVEGNPDVDYSIYTRELARLIR
YANIDFNELPDGEFDSPLGESTGASVIFGTTGGVIEAACRTAYELYTKKNLDKVDFEELRGLEGIRSATIDFNGTPVKIG
IAHGLGNARKLIEEVKNGTSPYHAIEVMACPGGCIGGGGQPFHRGRMEVLRRRASALYREDANKPLRKSHENPYIQQLYS
EYLGEPCGPKAHKLLHTHYIDRKEVIGMYIETEKSK
>Mature_596_residues
METIQLIIDNKEVEVPRGTTILDAAKSVGIHIPTLCYMKLEDLHYENNPGACRICVVEIEGRRNLAPSCKMECTEGMVVR
THTPRVMNARRTVMELILSNHPAECLTCSSNGHCELQKIAHDLGIREIRYKGEMSTFTIDRSPSIVRNMNKCIMCRRCET
MCNTIQTVGALTAVNRGFNAAVSTAFERDMAGSTCSYCGQCVSVCPVNALSGRNTQQPVLDALADPTKIVIAQTAPAVRT
ALGRDFGYEPGTLVTGKMVSALRQLGFDYVFDTDFAADLTIMEEGTELLHRLGSYLNGDKEVKIPLMTSCCPGWVSFVEQ
HFPELRDNLSTAKSPQQMFGAIAKSYFAEKLGVDRKDLVVVSIMPCLAKKYEASRPEFSVEGNPDVDYSIYTRELARLIR
YANIDFNELPDGEFDSPLGESTGASVIFGTTGGVIEAACRTAYELYTKKNLDKVDFEELRGLEGIRSATIDFNGTPVKIG
IAHGLGNARKLIEEVKNGTSPYHAIEVMACPGGCIGGGGQPFHRGRMEVLRRRASALYREDANKPLRKSHENPYIQQLYS
EYLGEPCGPKAHKLLHTHYIDRKEVIGMYIETEKSK

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=402, Percent_Identity=29.8507462686567, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI6912524, Length=404, Percent_Identity=27.970297029703, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI134284357, Length=339, Percent_Identity=29.7935103244838, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI84452151, Length=339, Percent_Identity=29.7935103244838, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI14165461, Length=447, Percent_Identity=26.8456375838926, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI33519475, Length=211, Percent_Identity=33.6492890995261, Blast_Score=116, Evalue=6e-26,
Organism=Escherichia coli, GI145693161, Length=220, Percent_Identity=28.1818181818182, Blast_Score=83, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17565758, Length=217, Percent_Identity=32.258064516129, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI32566231, Length=217, Percent_Identity=32.258064516129, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI193209088, Length=217, Percent_Identity=32.258064516129, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71995015, Length=366, Percent_Identity=28.1420765027322, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324089, Length=346, Percent_Identity=25.4335260115607, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI116007470, Length=415, Percent_Identity=28.6746987951807, Blast_Score=156, Evalue=5e-38,
Organism=Drosophila melanogaster, GI116007466, Length=415, Percent_Identity=28.6746987951807, Blast_Score=156, Evalue=5e-38,
Organism=Drosophila melanogaster, GI116007464, Length=415, Percent_Identity=28.6746987951807, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI116007468, Length=415, Percent_Identity=28.6746987951807, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI116007462, Length=288, Percent_Identity=31.9444444444444, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24640559, Length=217, Percent_Identity=32.258064516129, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24640557, Length=217, Percent_Identity=32.258064516129, Blast_Score=120, Evalue=3e-27,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 65945; Mature: 65945

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN ; PS01047 HMA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIQLIIDNKEVEVPRGTTILDAAKSVGIHIPTLCYMKLEDLHYENNPGACRICVVEIE
CCEEEEEEECCEECCCCCCHHHHHHHHCCCCCCHHHHEEHHHCCCCCCCCEEEEEEEEEC
GRRNLAPSCKMECTEGMVVRTHTPRVMNARRTVMELILSNHPAECLTCSSNGHCELQKIA
CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
HDLGIREIRYKGEMSTFTIDRSPSIVRNMNKCIMCRRCETMCNTIQTVGALTAVNRGFNA
HHCCCHHEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AVSTAFERDMAGSTCSYCGQCVSVCPVNALSGRNTQQPVLDALADPTKIVIAQTAPAVRT
HHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHCCCCEEEEECCCHHHHH
ALGRDFGYEPGTLVTGKMVSALRQLGFDYVFDTDFAADLTIMEEGTELLHRLGSYLNGDK
HHCCCCCCCCCCEEHHHHHHHHHHCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCC
EVKIPLMTSCCPGWVSFVEQHFPELRDNLSTAKSPQQMFGAIAKSYFAEKLGVDRKDLVV
EEEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHEEE
VSIMPCLAKKYEASRPEFSVEGNPDVDYSIYTRELARLIRYANIDFNELPDGEFDSPLGE
EHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
STGASVIFGTTGGVIEAACRTAYELYTKKNLDKVDFEELRGLEGIRSATIDFNGTPVKIG
CCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHEEEECCCCEEEEE
IAHGLGNARKLIEEVKNGTSPYHAIEVMACPGGCIGGGGQPFHRGRMEVLRRRASALYRE
EECCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DANKPLRKSHENPYIQQLYSEYLGEPCGPKAHKLLHTHYIDRKEVIGMYIETEKSK
HCCCCHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHEEEEEEECCCC
>Mature Secondary Structure
METIQLIIDNKEVEVPRGTTILDAAKSVGIHIPTLCYMKLEDLHYENNPGACRICVVEIE
CCEEEEEEECCEECCCCCCHHHHHHHHCCCCCCHHHHEEHHHCCCCCCCCEEEEEEEEEC
GRRNLAPSCKMECTEGMVVRTHTPRVMNARRTVMELILSNHPAECLTCSSNGHCELQKIA
CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
HDLGIREIRYKGEMSTFTIDRSPSIVRNMNKCIMCRRCETMCNTIQTVGALTAVNRGFNA
HHCCCHHEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AVSTAFERDMAGSTCSYCGQCVSVCPVNALSGRNTQQPVLDALADPTKIVIAQTAPAVRT
HHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHCCCCEEEEECCCHHHHH
ALGRDFGYEPGTLVTGKMVSALRQLGFDYVFDTDFAADLTIMEEGTELLHRLGSYLNGDK
HHCCCCCCCCCCEEHHHHHHHHHHCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCC
EVKIPLMTSCCPGWVSFVEQHFPELRDNLSTAKSPQQMFGAIAKSYFAEKLGVDRKDLVV
EEEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHEEE
VSIMPCLAKKYEASRPEFSVEGNPDVDYSIYTRELARLIRYANIDFNELPDGEFDSPLGE
EHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
STGASVIFGTTGGVIEAACRTAYELYTKKNLDKVDFEELRGLEGIRSATIDFNGTPVKIG
CCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHEEEECCCCEEEEE
IAHGLGNARKLIEEVKNGTSPYHAIEVMACPGGCIGGGGQPFHRGRMEVLRRRASALYRE
EECCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DANKPLRKSHENPYIQQLYSEYLGEPCGPKAHKLLHTHYIDRKEVIGMYIETEKSK
HCCCCHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]