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The map label for this gene is nuoE [H]

Identifier: 150007690

GI number: 150007690

Start: 1211600

End: 1212088

Strand: Direct

Name: nuoE [H]

Synonym: BDI_1045

Alternate gene names: 150007690

Gene position: 1211600-1212088 (Clockwise)

Preceding gene: 150007689

Following gene: 150007693

Centisome position: 25.18

GC content: 48.06

Gene sequence:

>489_bases
ATGAATGAGATACATTTGCCTAAAACAAAAGTAGCGGAGCTACATGCGATATGCGCTGAACGCAACAACGATCCCGGGGA
GTTGATCAATATCTTGCACGCCGCCCAAGGCTTGTTCGGATATTTACCACCGGAAGTCCAACAGGTTATCGCCGCCGAAT
TGAATATCCCGGTCTCAAGGGTATATGGCGTAGTTACTTTTTACTCATTCTTTACGATGACCCCCAAAGGGAAATACCCC
ATCTCTGTTTGTCTGGGAACGGCCTGTTACGTGCGTGGCGCAGAAAATGTTCTGGAAGAAATGCAACGTCAATTGGAAAT
AAAGGTAGGAGAGACTACACCGGACGGTTTGTTCTCCTTGGATTGCTTACGCTGTGTCGGTGCTTGCGGATTAGCTCCGG
TGGTCATGATCGGCGGGAAGGTCTATGGAAGGGTTACTCCCGAGAAGGTACGGGATATACTTTCCGACTACTATCTGAAA
GAGCAATAA

Upstream 100 bases:

>100_bases
GCCTTGCGGACCGAAAGCCCATAAATTACTGCATACCCATTACATAGATCGTAAGGAAGTAATCGGTATGTATATAGAAA
CCGAAAAAAGTAAATAAGCC

Downstream 100 bases:

>100_bases
GATACGAAAACACAAGCGGTCACATAAAGTTTTACGTGACCGCTTGTATAAAATAATGCGAATAATCGTATTTTCAGAAA
CGACTGATCGAACCGCCACC

Product: NADH:ubiquinone oxidoreductase subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MNEIHLPKTKVAELHAICAERNNDPGELINILHAAQGLFGYLPPEVQQVIAAELNIPVSRVYGVVTFYSFFTMTPKGKYP
ISVCLGTACYVRGAENVLEEMQRQLEIKVGETTPDGLFSLDCLRCVGACGLAPVVMIGGKVYGRVTPEKVRDILSDYYLK
EQ

Sequences:

>Translated_162_residues
MNEIHLPKTKVAELHAICAERNNDPGELINILHAAQGLFGYLPPEVQQVIAAELNIPVSRVYGVVTFYSFFTMTPKGKYP
ISVCLGTACYVRGAENVLEEMQRQLEIKVGETTPDGLFSLDCLRCVGACGLAPVVMIGGKVYGRVTPEKVRDILSDYYLK
EQ
>Mature_162_residues
MNEIHLPKTKVAELHAICAERNNDPGELINILHAAQGLFGYLPPEVQQVIAAELNIPVSRVYGVVTFYSFFTMTPKGKYP
ISVCLGTACYVRGAENVLEEMQRQLEIKVGETTPDGLFSLDCLRCVGACGLAPVVMIGGKVYGRVTPEKVRDILSDYYLK
EQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=129, Percent_Identity=41.0852713178295, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1788621, Length=167, Percent_Identity=34.1317365269461, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561328, Length=131, Percent_Identity=42.7480916030534, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI18859877, Length=131, Percent_Identity=41.9847328244275, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21355353, Length=131, Percent_Identity=34.3511450381679, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17864; Mature: 17864

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEIHLPKTKVAELHAICAERNNDPGELINILHAAQGLFGYLPPEVQQVIAAELNIPVSR
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
VYGVVTFYSFFTMTPKGKYPISVCLGTACYVRGAENVLEEMQRQLEIKVGETTPDGLFSL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEEEECCCCCCHHHHH
DCLRCVGACGLAPVVMIGGKVYGRVTPEKVRDILSDYYLKEQ
HHHHHHHHCCHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNEIHLPKTKVAELHAICAERNNDPGELINILHAAQGLFGYLPPEVQQVIAAELNIPVSR
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
VYGVVTFYSFFTMTPKGKYPISVCLGTACYVRGAENVLEEMQRQLEIKVGETTPDGLFSL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEEEECCCCCCHHHHH
DCLRCVGACGLAPVVMIGGKVYGRVTPEKVRDILSDYYLKEQ
HHHHHHHHCCHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]