Click here to switch to the map view.

The map label for this gene is glsA

Identifier: 150007469

GI number: 150007469

Start: 967750

End: 968715

Strand: Reverse

Name: glsA

Synonym: BDI_0820

Alternate gene names: 150007469

Gene position: 968715-967750 (Counterclockwise)

Preceding gene: 150007470

Following gene: 150007466

Centisome position: 20.13

GC content: 44.72

Gene sequence:

>966_bases
ATGGACAAAAAAATAACGATCGCCCAAATAAAGGAAGTAGCTCAACAGGCTTACGATCTTTACAAGACAAATACGGATGG
TAAGAATGCCGATTACATTCCTTATCTGGCGAATATCAATAAAAATCTATTCGGAATCAGTATTTGCCTTTTAAACGGAC
AAACCATCGAGGTGGGAGATTCCGAATATCGTTTCGGTATCGAATCCGTATCGAAAGTACACACCGCTATCTTGGTACTG
CGCCAATACGGAGCGAAAGAATTATTGGAGAAAATTGGTGCCGACGCTACCGGATTGCCATTTAACTCCATCATCGCTAT
CCTATTGGAAAACGACCATCCTTCTACCCCATTGGTAAATGCCGGCGCTATCACGGCTTGTAGTATGGTGAAGCCTGTCG
GTGATTCCAAACAGAAGTGGGATGCTATCGTAGCCAATATCACGGATTTATGCGGAAGCGCACCGCAGTTGATCGACGAA
CTCTACAAATCCGAGTCCGCAACGAACTTCAATAACCGCTCCATCGCTTGGTTGCTAAAGAATTACAATCGCATTTATGA
CGATCCGGATATGTCTTTGGATCTGTATACCCGTCAATGTTCTTTGGGTATCACGGCTAAGCAACTATCTGTCGCTGCCG
CTACGGTCGCAAATTTAGGTCTCAATCCTGTGACAAAGAAACAAGTATTCGATGCAGAATTATCTCCGAAGATCACTTCC
ATGATCTCTACCGTAGGTTTTTATGAACACACCGGTGATTGGTTGTACACTTCCGGTATTCCCGCAAAAACTGGCGTAGG
CGGTGGTGTCATGGGTGTACTTCCCGGACAATTCGGTATTTCCGCATTCGCTCCTCCTATTGACCAAGCTGGTAACTCTG
TAAAGGCACAGCTTGCTATTAAGTATGTAATGAATAAACTCGGATTGAACGTGTTCAACGGTCACCGTGTGACGATCGTT
GACTAA

Upstream 100 bases:

>100_bases
CGCAATGAGCAACGCTAAGAAATAAAAACAAAATTCATCAAGGCGTGCATGAAAGGACTATCAGTGTTTTCATACACGCC
TTCTTTAATCCAATTCATAT

Downstream 100 bases:

>100_bases
TAGACTGAATCAGTTTAAACGAGAAGTAGTATAGAAAAAGTGTTTCATTACGATGGGCTGTTATACCATCTAAATGAAAC
ACTTTATTTTTTGTATCAAT

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MDKKITIAQIKEVAQQAYDLYKTNTDGKNADYIPYLANINKNLFGISICLLNGQTIEVGDSEYRFGIESVSKVHTAILVL
RQYGAKELLEKIGADATGLPFNSIIAILLENDHPSTPLVNAGAITACSMVKPVGDSKQKWDAIVANITDLCGSAPQLIDE
LYKSESATNFNNRSIAWLLKNYNRIYDDPDMSLDLYTRQCSLGITAKQLSVAAATVANLGLNPVTKKQVFDAELSPKITS
MISTVGFYEHTGDWLYTSGIPAKTGVGGGVMGVLPGQFGISAFAPPIDQAGNSVKAQLAIKYVMNKLGLNVFNGHRVTIV
D

Sequences:

>Translated_321_residues
MDKKITIAQIKEVAQQAYDLYKTNTDGKNADYIPYLANINKNLFGISICLLNGQTIEVGDSEYRFGIESVSKVHTAILVL
RQYGAKELLEKIGADATGLPFNSIIAILLENDHPSTPLVNAGAITACSMVKPVGDSKQKWDAIVANITDLCGSAPQLIDE
LYKSESATNFNNRSIAWLLKNYNRIYDDPDMSLDLYTRQCSLGITAKQLSVAAATVANLGLNPVTKKQVFDAELSPKITS
MISTVGFYEHTGDWLYTSGIPAKTGVGGGVMGVLPGQFGISAFAPPIDQAGNSVKAQLAIKYVMNKLGLNVFNGHRVTIV
D
>Mature_321_residues
MDKKITIAQIKEVAQQAYDLYKTNTDGKNADYIPYLANINKNLFGISICLLNGQTIEVGDSEYRFGIESVSKVHTAILVL
RQYGAKELLEKIGADATGLPFNSIIAILLENDHPSTPLVNAGAITACSMVKPVGDSKQKWDAIVANITDLCGSAPQLIDE
LYKSESATNFNNRSIAWLLKNYNRIYDDPDMSLDLYTRQCSLGITAKQLSVAAATVANLGLNPVTKKQVFDAELSPKITS
MISTVGFYEHTGDWLYTSGIPAKTGVGGGVMGVLPGQFGISAFAPPIDQAGNSVKAQLAIKYVMNKLGLNVFNGHRVTIV
D

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=284, Percent_Identity=32.7464788732394, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI20336214, Length=299, Percent_Identity=31.7725752508361, Blast_Score=156, Evalue=3e-38,
Organism=Escherichia coli, GI1786693, Length=306, Percent_Identity=43.7908496732026, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1787804, Length=288, Percent_Identity=30.5555555555556, Blast_Score=183, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI193204073, Length=313, Percent_Identity=30.0319488817891, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI193204075, Length=315, Percent_Identity=29.8412698412698, Blast_Score=169, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17532727, Length=297, Percent_Identity=30.976430976431, Blast_Score=154, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17507019, Length=292, Percent_Identity=31.1643835616438, Blast_Score=147, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24653166, Length=310, Percent_Identity=33.5483870967742, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24653164, Length=310, Percent_Identity=32.9032258064516, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24653156, Length=307, Percent_Identity=33.2247557003257, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI281363241, Length=310, Percent_Identity=32.9032258064516, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI281363239, Length=307, Percent_Identity=33.2247557003257, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24653162, Length=310, Percent_Identity=32.9032258064516, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI116008307, Length=310, Percent_Identity=33.5483870967742, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24653158, Length=307, Percent_Identity=33.2247557003257, Blast_Score=172, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA_PARD8 (A6LA76)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001302212.1
- ProteinModelPortal:   A6LA76
- SMR:   A6LA76
- STRING:   A6LA76
- GeneID:   5305974
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_0820
- eggNOG:   COG2066
- HOGENOM:   HBG512335
- OMA:   LLENDHP
- ProtClustDB:   PRK12356
- BioCyc:   PDIS435591:BDI_0820-MONOMER
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 34670; Mature: 34670

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKITIAQIKEVAQQAYDLYKTNTDGKNADYIPYLANINKNLFGISICLLNGQTIEVGD
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEECC
SEYRFGIESVSKVHTAILVLRQYGAKELLEKIGADATGLPFNSIIAILLENDHPSTPLVN
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHEEEEEECCCCCCCCEEC
AGAITACSMVKPVGDSKQKWDAIVANITDLCGSAPQLIDELYKSESATNFNNRSIAWLLK
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
NYNRIYDDPDMSLDLYTRQCSLGITAKQLSVAAATVANLGLNPVTKKQVFDAELSPKITS
HCHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHH
MISTVGFYEHTGDWLYTSGIPAKTGVGGGVMGVLPGQFGISAFAPPIDQAGNSVKAQLAI
HHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECCCCCCCHHCCCCHHHCCCCHHHHHHH
KYVMNKLGLNVFNGHRVTIVD
HHHHHHHCCEEECCCEEEEEC
>Mature Secondary Structure
MDKKITIAQIKEVAQQAYDLYKTNTDGKNADYIPYLANINKNLFGISICLLNGQTIEVGD
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEECC
SEYRFGIESVSKVHTAILVLRQYGAKELLEKIGADATGLPFNSIIAILLENDHPSTPLVN
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHEEEEEECCCCCCCCEEC
AGAITACSMVKPVGDSKQKWDAIVANITDLCGSAPQLIDELYKSESATNFNNRSIAWLLK
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
NYNRIYDDPDMSLDLYTRQCSLGITAKQLSVAAATVANLGLNPVTKKQVFDAELSPKITS
HCHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHH
MISTVGFYEHTGDWLYTSGIPAKTGVGGGVMGVLPGQFGISAFAPPIDQAGNSVKAQLAI
HHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECCCCCCCHHCCCCHHHCCCCHHHHHHH
KYVMNKLGLNVFNGHRVTIVD
HHHHHHHCCEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA