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The map label for this gene is dcp [H]

Identifier: 150006873

GI number: 150006873

Start: 212688

End: 214787

Strand: Reverse

Name: dcp [H]

Synonym: BDI_0207

Alternate gene names: 150006873

Gene position: 214787-212688 (Counterclockwise)

Preceding gene: 150006877

Following gene: 150006872

Centisome position: 4.46

GC content: 43.9

Gene sequence:

>2100_bases
ATGAGGAAGTTATTATATAATGTAGTAATTTTATTAAGCGCAATTCAAATGACACACGCAGCAAATAACCCTTTCTTCGG
GAAGTTTAAAACACCGTTCGAGACCCCTCCTTTCGATAAGATCAAGATCGAGCATTATGAGCCCGCTTTCGACGAAGGAA
TCAAGCAAATGGAAAAAGAGGTGCAAGAGATCGCCAATAACCCGCAACCGGCTACTTTCGAGAATACGGTAGTAGCTCTG
GAACGTAGCGGCAAATTATTAGAAACAGTCTCTTCTGTTTTTTTTAATGTATTAGGGGCAGAGGCTAACGACGAAATGAT
GGAAATCTCGCAACGTGTCTCCCCGAAGTTATCCCAGACATCCAATAACATCTTCTTAAATGAGAAGCTACTTGCTCGGG
TCAAATCAATCTATGATAAAAAAGAACAATTGAACCTTTCTACCGAGGATGCTAAATTGCTGGAAGACCTTTACGAGTCG
TTTAAAGCGAATGGGGCTACGTTAAATAAAGATGACAAGGAAAAATACCGCAAGCTAAGTATGGACCTAAGCATGTTAAC
CTTGCAGTTCGATCAAAACGCCTTGAAAGATAAAAACCGATTCGAATTACTAATAACGGACGAGAACGAACTATCCGGCT
TACCCGAAAGTGCTCGTGACGCAGCGGCCATGTTAGCCAAAAGTAAAGATAAAAATGGATGGTTATTCAATCTCTCGGCT
CCGAGTTACATTCCATTTATGCGTTATTCCGACAAGCGTGATTTGCGAGAAAAAATGTATCGTGAATACATGAGCGTAGG
AAATAAAGGGGATGAGTTCGACAATAAGGACATTATCAAAAAGATCGTTAATATCCGCCTAGAGATCGCCCAGTTGATGG
GATTCAAGAATTACGCCGAATATGCGCTGGAACACACGATGGCTAAAAACTCAGCGAACGTATACAAATTATTGAATCAG
TTACTCGAAGCTTATAAACCGATAGCGATCAACGAATACAATGCAGTAGAAGGATTCGCATTAGGTACAGAGAAAGAGAA
TATCACCGTTATGCCTTGGGACTGGAGTTATTATTCCGAGAAGTTACGGGATATCCGCTTCAAGGTAAACGACGAGATGA
CTCGCCCTTATTTCGAGTTAAGCAACGTAAAGAAAGGCGTATTCGGATTAGCTACCCAGCTCTACGGTATCACCTTTAAG
GAAAACAAGAAAATCCCGGTTTATCATCCGGAAGTAGACGCTTATGAGGTATACGATGCCGATGGTAAGTTCCTTGCTAT
CCTTTATACGGATTTCTTCCCTCGTGACGGAAAACAATCCGGCGCTTGGATGAACAATATCAAGGCTCAATACAAAGATA
AAGACGGAAAAGATAGCCGTCCTCAGATCGTTATCGTGATGAACTTTACCCGTCCGACAGACACGAAGCCCTCTTTGTTA
AGTTTCGACGAGGTGAACACGCTCTTGCATGAGTTCGGGCACTCCTTGCACGGCATGCTAGCGCAAGGAACCTATTCCAG
CCTTTCGGGAACCAGCGTTTATCGTGATTTCGTAGAATTACCTTCCCAGATCATGGAGAACTGGTTGACTGAAAAAGAGT
TCTTAGATCAGATCGCCGTTCATTACCAGACCGGAGAGAAAATCCCGCAAGAGATGATACAAAGCTTGGTAAACGCCTCT
AACTTCAACGCCGGCTACCTTTGCTGCCGCCAATTAAGCTTTGGCTTGCTGGATATGGCATGGCATACGTTGGAGCAACC
TTTCGACGGTGACGTAGCGACATTCGAGAAAAAAGCTTGGGCTCCGACGGTAATCGTACCGGAAGTACCGGAAGCCTTGA
TGGGCACAAGCTTCGGACATATCTTCTCCGGAGGATACGCGGCAGGCTATTACGGATATAAATGGGCCGAGGTATTAGAC
GCCGACGCTTTCTCCGTTTTCAAATCGAAAGGAATCTTCAACAAGGAGGTCGCGAAATCTTTCCGTGACAATATCTTATC
CAAAGGTGGTACAGAAGATCCCGCCGTGTTATACAAGCGTTTCCGTGGACAAGAGCCTACGATAGACGCCTTATTAATCC
GTAATGGTATTAAGAAGTAA

Upstream 100 bases:

>100_bases
ATTTTTCATTTTAAATCAATCTGAATATAAAAACAGATGCCTATAATGTTCCTGTGATTAAAATGCCTACCTTTGCGGAA
ATTTTCAAACAATTTTTAAT

Downstream 100 bases:

>100_bases
TAATTTACCGGGCTTATCGCCCGGTAAATCTAAATAATCACTACCTTTGTGTCTGGATTAAAAGACAAAAGAGTAAACAA
ATGTGCGAGAAAACAGAAAA

Product: peptidyl-dipeptidase

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MRKLLYNVVILLSAIQMTHAANNPFFGKFKTPFETPPFDKIKIEHYEPAFDEGIKQMEKEVQEIANNPQPATFENTVVAL
ERSGKLLETVSSVFFNVLGAEANDEMMEISQRVSPKLSQTSNNIFLNEKLLARVKSIYDKKEQLNLSTEDAKLLEDLYES
FKANGATLNKDDKEKYRKLSMDLSMLTLQFDQNALKDKNRFELLITDENELSGLPESARDAAAMLAKSKDKNGWLFNLSA
PSYIPFMRYSDKRDLREKMYREYMSVGNKGDEFDNKDIIKKIVNIRLEIAQLMGFKNYAEYALEHTMAKNSANVYKLLNQ
LLEAYKPIAINEYNAVEGFALGTEKENITVMPWDWSYYSEKLRDIRFKVNDEMTRPYFELSNVKKGVFGLATQLYGITFK
ENKKIPVYHPEVDAYEVYDADGKFLAILYTDFFPRDGKQSGAWMNNIKAQYKDKDGKDSRPQIVIVMNFTRPTDTKPSLL
SFDEVNTLLHEFGHSLHGMLAQGTYSSLSGTSVYRDFVELPSQIMENWLTEKEFLDQIAVHYQTGEKIPQEMIQSLVNAS
NFNAGYLCCRQLSFGLLDMAWHTLEQPFDGDVATFEKKAWAPTVIVPEVPEALMGTSFGHIFSGGYAAGYYGYKWAEVLD
ADAFSVFKSKGIFNKEVAKSFRDNILSKGGTEDPAVLYKRFRGQEPTIDALLIRNGIKK

Sequences:

>Translated_699_residues
MRKLLYNVVILLSAIQMTHAANNPFFGKFKTPFETPPFDKIKIEHYEPAFDEGIKQMEKEVQEIANNPQPATFENTVVAL
ERSGKLLETVSSVFFNVLGAEANDEMMEISQRVSPKLSQTSNNIFLNEKLLARVKSIYDKKEQLNLSTEDAKLLEDLYES
FKANGATLNKDDKEKYRKLSMDLSMLTLQFDQNALKDKNRFELLITDENELSGLPESARDAAAMLAKSKDKNGWLFNLSA
PSYIPFMRYSDKRDLREKMYREYMSVGNKGDEFDNKDIIKKIVNIRLEIAQLMGFKNYAEYALEHTMAKNSANVYKLLNQ
LLEAYKPIAINEYNAVEGFALGTEKENITVMPWDWSYYSEKLRDIRFKVNDEMTRPYFELSNVKKGVFGLATQLYGITFK
ENKKIPVYHPEVDAYEVYDADGKFLAILYTDFFPRDGKQSGAWMNNIKAQYKDKDGKDSRPQIVIVMNFTRPTDTKPSLL
SFDEVNTLLHEFGHSLHGMLAQGTYSSLSGTSVYRDFVELPSQIMENWLTEKEFLDQIAVHYQTGEKIPQEMIQSLVNAS
NFNAGYLCCRQLSFGLLDMAWHTLEQPFDGDVATFEKKAWAPTVIVPEVPEALMGTSFGHIFSGGYAAGYYGYKWAEVLD
ADAFSVFKSKGIFNKEVAKSFRDNILSKGGTEDPAVLYKRFRGQEPTIDALLIRNGIKK
>Mature_699_residues
MRKLLYNVVILLSAIQMTHAANNPFFGKFKTPFETPPFDKIKIEHYEPAFDEGIKQMEKEVQEIANNPQPATFENTVVAL
ERSGKLLETVSSVFFNVLGAEANDEMMEISQRVSPKLSQTSNNIFLNEKLLARVKSIYDKKEQLNLSTEDAKLLEDLYES
FKANGATLNKDDKEKYRKLSMDLSMLTLQFDQNALKDKNRFELLITDENELSGLPESARDAAAMLAKSKDKNGWLFNLSA
PSYIPFMRYSDKRDLREKMYREYMSVGNKGDEFDNKDIIKKIVNIRLEIAQLMGFKNYAEYALEHTMAKNSANVYKLLNQ
LLEAYKPIAINEYNAVEGFALGTEKENITVMPWDWSYYSEKLRDIRFKVNDEMTRPYFELSNVKKGVFGLATQLYGITFK
ENKKIPVYHPEVDAYEVYDADGKFLAILYTDFFPRDGKQSGAWMNNIKAQYKDKDGKDSRPQIVIVMNFTRPTDTKPSLL
SFDEVNTLLHEFGHSLHGMLAQGTYSSLSGTSVYRDFVELPSQIMENWLTEKEFLDQIAVHYQTGEKIPQEMIQSLVNAS
NFNAGYLCCRQLSFGLLDMAWHTLEQPFDGDVATFEKKAWAPTVIVPEVPEALMGTSFGHIFSGGYAAGYYGYKWAEVLD
ADAFSVFKSKGIFNKEVAKSFRDNILSKGGTEDPAVLYKRFRGQEPTIDALLIRNGIKK

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=638, Percent_Identity=30.7210031347962, Blast_Score=323, Evalue=4e-88,
Organism=Homo sapiens, GI14149738, Length=607, Percent_Identity=28.665568369028, Blast_Score=246, Evalue=5e-65,
Organism=Homo sapiens, GI156105687, Length=673, Percent_Identity=24.665676077266, Blast_Score=192, Evalue=1e-48,
Organism=Escherichia coli, GI1787819, Length=679, Percent_Identity=39.0279823269514, Blast_Score=479, Evalue=1e-136,
Organism=Escherichia coli, GI1789913, Length=681, Percent_Identity=38.3259911894273, Blast_Score=466, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI32565901, Length=609, Percent_Identity=21.6748768472906, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71999758, Length=577, Percent_Identity=22.5303292894281, Blast_Score=102, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6319793, Length=658, Percent_Identity=28.7234042553192, Blast_Score=246, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6322715, Length=701, Percent_Identity=23.5378031383738, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356111, Length=546, Percent_Identity=26.1904761904762, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI20129717, Length=413, Percent_Identity=26.3922518159806, Blast_Score=154, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 79870; Mature: 79870

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLLYNVVILLSAIQMTHAANNPFFGKFKTPFETPPFDKIKIEHYEPAFDEGIKQMEKE
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
VQEIANNPQPATFENTVVALERSGKLLETVSSVFFNVLGAEANDEMMEISQRVSPKLSQT
HHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHC
SNNIFLNEKLLARVKSIYDKKEQLNLSTEDAKLLEDLYESFKANGATLNKDDKEKYRKLS
CCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
MDLSMLTLQFDQNALKDKNRFELLITDENELSGLPESARDAAAMLAKSKDKNGWLFNLSA
CCHHHEEEECCCHHHCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECC
PSYIPFMRYSDKRDLREKMYREYMSVGNKGDEFDNKDIIKKIVNIRLEIAQLMGFKNYAE
CCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHH
YALEHTMAKNSANVYKLLNQLLEAYKPIAINEYNAVEGFALGTEKENITVMPWDWSYYSE
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEEECCCCCCEEEEECCHHHHHH
KLRDIRFKVNDEMTRPYFELSNVKKGVFGLATQLYGITFKENKKIPVYHPEVDAYEVYDA
HHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEECCCCCCEEEECC
DGKFLAILYTDFFPRDGKQSGAWMNNIKAQYKDKDGKDSRPQIVIVMNFTRPTDTKPSLL
CCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCC
SFDEVNTLLHEFGHSLHGMLAQGTYSSLSGTSVYRDFVELPSQIMENWLTEKEFLDQIAV
CHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HYQTGEKIPQEMIQSLVNASNFNAGYLCCRQLSFGLLDMAWHTLEQPFDGDVATFEKKAW
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCC
APTVIVPEVPEALMGTSFGHIFSGGYAAGYYGYKWAEVLDADAFSVFKSKGIFNKEVAKS
CCEEECCCCCHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
FRDNILSKGGTEDPAVLYKRFRGQEPTIDALLIRNGIKK
HHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MRKLLYNVVILLSAIQMTHAANNPFFGKFKTPFETPPFDKIKIEHYEPAFDEGIKQMEKE
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
VQEIANNPQPATFENTVVALERSGKLLETVSSVFFNVLGAEANDEMMEISQRVSPKLSQT
HHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHC
SNNIFLNEKLLARVKSIYDKKEQLNLSTEDAKLLEDLYESFKANGATLNKDDKEKYRKLS
CCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
MDLSMLTLQFDQNALKDKNRFELLITDENELSGLPESARDAAAMLAKSKDKNGWLFNLSA
CCHHHEEEECCCHHHCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECC
PSYIPFMRYSDKRDLREKMYREYMSVGNKGDEFDNKDIIKKIVNIRLEIAQLMGFKNYAE
CCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHH
YALEHTMAKNSANVYKLLNQLLEAYKPIAINEYNAVEGFALGTEKENITVMPWDWSYYSE
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEEECCCCCCEEEEECCHHHHHH
KLRDIRFKVNDEMTRPYFELSNVKKGVFGLATQLYGITFKENKKIPVYHPEVDAYEVYDA
HHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEECCCCCCEEEECC
DGKFLAILYTDFFPRDGKQSGAWMNNIKAQYKDKDGKDSRPQIVIVMNFTRPTDTKPSLL
CCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCC
SFDEVNTLLHEFGHSLHGMLAQGTYSSLSGTSVYRDFVELPSQIMENWLTEKEFLDQIAV
CHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HYQTGEKIPQEMIQSLVNASNFNAGYLCCRQLSFGLLDMAWHTLEQPFDGDVATFEKKAW
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCC
APTVIVPEVPEALMGTSFGHIFSGGYAAGYYGYKWAEVLDADAFSVFKSKGIFNKEVAKS
CCEEECCCCCHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
FRDNILSKGGTEDPAVLYKRFRGQEPTIDALLIRNGIKK
HHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]