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The map label for this gene is cobL [H]

Identifier: 150005594

GI number: 150005594

Start: 3896595

End: 3897788

Strand: Reverse

Name: cobL [H]

Synonym: BVU_3082

Alternate gene names: 150005594

Gene position: 3897788-3896595 (Counterclockwise)

Preceding gene: 150005595

Following gene: 150005593

Centisome position: 75.49

GC content: 47.49

Gene sequence:

>1194_bases
ATGTATAAGTCCATGCAAACATTCTATATAATAGGTATAAGCGATAACCGGAATCAATTTCTTTCTCCTGAAATCCGGAA
CTTGGTTTCTCAAGGGAAAGTCTTCTCGGGAGGAAAACGTCATCACGAACTGGTACACGCTTATTTGCCGGAAGATGCCG
TATGGATAGACATCACCGTCCCGCTGGATACGGTATTCTCCCGTTACGAGGAACATCCCGAAATAATCGTTTTCGCTTCG
GGCGACCCGTTGTTTTTCGGCTTCGCCAATACCGTCATGAGAAAACTCCCGTCGGCAAAGATTATCTTATTCCCCACCTT
CAACTCGCTGCAAATGCTGGCACACCGTATATTGCTCCCCTATCAGGAGATGCAGACCTTGTCGCTGACCGGACGTCCTT
GGGATGCATTCGACTCTGCTTTAATCAGAGGAGATAAACTGATAGGCGTGTTGACCGACCGGGAAAAGACACCTGCCACC
ATTGCCGCCCGGATGCTGGAGTATGGATATGACAACTACCGCATGACCGTGGGGGAAGCATTAGGCAATGGCGAGGAAGA
ATCTGTACGTACATTCTCTTTAGAGGAAGCCTCCCAATCTGCTTTCCGCTTTCCCAATTGCCTGATACTGCAAAGAAACA
AGGTGCATCCCCGTCCGTTCGGAATTCCCGAAAGTGAGTTTCATCTGTTGAACGGACGCAACAGAATGATTACCAAAATG
CCTGTCCGCTTGCTTACTCTCAGTATGCTGACATTAAGGGAAAAGAAATCATTCTGGGACATCGGTTTCTGCACCGGCTC
TGTTTCCATAGAAGCCAAGCTCCAATTTCCGGAGCTGAAAGTGACAGCATTCGAACAGCGTACGGAAGGTAAAGAGTTAA
TGGAACGCAACAGTCGTAAATTCGGCACGCCCGGCATTACAACCGTCATGGGTGATTTTCTGGAAACGGAACTCGGCGGA
CTTCCCGCCCCCGATGCCGTATTTATAGGTGGTCATGGAGGAAAAATGATAGAGATTCTACAAAAAATCAAAGAAGTGCT
GTTGCCTGACGGAGTCATTGTATTCAATTCGGTTTCGGAAGAGAGCAAGGCCCTGTTCACAAAAGGTATAACGCAAATCA
ACAAGAAGGTAACACAGTGTACCCGTATTGCTGTGGATGCCTTTAATCCGATAGAGATAATGAGAGCGGAATAA

Upstream 100 bases:

>100_bases
CTGATAGTAGAAGGACGCAAAGGGGGAAGCAATCTGGCAGCGACTCTGGTAAATGCCATCCTTACTTTTGATGATGCGGA
ACAACTGAAACCGGGAAGAG

Downstream 100 bases:

>100_bases
ATGATTTAAAACAGATAACAAATGAAAGCAATCATACTGATATCAGAAGCCAGCCTGCCGTTGGCAAAAACACTACAAAG
AGAGTTGCCGGATACCCTTA

Product: decarboxylating precorrin-6y C5,15-methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MYKSMQTFYIIGISDNRNQFLSPEIRNLVSQGKVFSGGKRHHELVHAYLPEDAVWIDITVPLDTVFSRYEEHPEIIVFAS
GDPLFFGFANTVMRKLPSAKIILFPTFNSLQMLAHRILLPYQEMQTLSLTGRPWDAFDSALIRGDKLIGVLTDREKTPAT
IAARMLEYGYDNYRMTVGEALGNGEEESVRTFSLEEASQSAFRFPNCLILQRNKVHPRPFGIPESEFHLLNGRNRMITKM
PVRLLTLSMLTLREKKSFWDIGFCTGSVSIEAKLQFPELKVTAFEQRTEGKELMERNSRKFGTPGITTVMGDFLETELGG
LPAPDAVFIGGHGGKMIEILQKIKEVLLPDGVIVFNSVSEESKALFTKGITQINKKVTQCTRIAVDAFNPIEIMRAE

Sequences:

>Translated_397_residues
MYKSMQTFYIIGISDNRNQFLSPEIRNLVSQGKVFSGGKRHHELVHAYLPEDAVWIDITVPLDTVFSRYEEHPEIIVFAS
GDPLFFGFANTVMRKLPSAKIILFPTFNSLQMLAHRILLPYQEMQTLSLTGRPWDAFDSALIRGDKLIGVLTDREKTPAT
IAARMLEYGYDNYRMTVGEALGNGEEESVRTFSLEEASQSAFRFPNCLILQRNKVHPRPFGIPESEFHLLNGRNRMITKM
PVRLLTLSMLTLREKKSFWDIGFCTGSVSIEAKLQFPELKVTAFEQRTEGKELMERNSRKFGTPGITTVMGDFLETELGG
LPAPDAVFIGGHGGKMIEILQKIKEVLLPDGVIVFNSVSEESKALFTKGITQINKKVTQCTRIAVDAFNPIEIMRAE
>Mature_397_residues
MYKSMQTFYIIGISDNRNQFLSPEIRNLVSQGKVFSGGKRHHELVHAYLPEDAVWIDITVPLDTVFSRYEEHPEIIVFAS
GDPLFFGFANTVMRKLPSAKIILFPTFNSLQMLAHRILLPYQEMQTLSLTGRPWDAFDSALIRGDKLIGVLTDREKTPAT
IAARMLEYGYDNYRMTVGEALGNGEEESVRTFSLEEASQSAFRFPNCLILQRNKVHPRPFGIPESEFHLLNGRNRMITKM
PVRLLTLSMLTLREKKSFWDIGFCTGSVSIEAKLQFPELKVTAFEQRTEGKELMERNSRKFGTPGITTVMGDFLETELGG
LPAPDAVFIGGHGGKMIEILQKIKEVLLPDGVIVFNSVSEESKALFTKGITQINKKVTQCTRIAVDAFNPIEIMRAE

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 44821; Mature: 44821

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKSMQTFYIIGISDNRNQFLSPEIRNLVSQGKVFSGGKRHHELVHAYLPEDAVWIDITV
CCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEEEC
PLDTVFSRYEEHPEIIVFASGDPLFFGFANTVMRKLPSAKIILFPTFNSLQMLAHRILLP
CHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCC
YQEMQTLSLTGRPWDAFDSALIRGDKLIGVLTDREKTPATIAARMLEYGYDNYRMTVGEA
HHHHHEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEHHH
LGNGEEESVRTFSLEEASQSAFRFPNCLILQRNKVHPRPFGIPESEFHLLNGRNRMITKM
HCCCCCHHEEEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCEEHHH
PVRLLTLSMLTLREKKSFWDIGFCTGSVSIEAKLQFPELKVTAFEQRTEGKELMERNSRK
HHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEEEECCCEEEEEHHHHCCHHHHHHHCCCC
FGTPGITTVMGDFLETELGGLPAPDAVFIGGHGGKMIEILQKIKEVLLPDGVIVFNSVSE
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCH
ESKALFTKGITQINKKVTQCTRIAVDAFNPIEIMRAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure
MYKSMQTFYIIGISDNRNQFLSPEIRNLVSQGKVFSGGKRHHELVHAYLPEDAVWIDITV
CCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEEEC
PLDTVFSRYEEHPEIIVFASGDPLFFGFANTVMRKLPSAKIILFPTFNSLQMLAHRILLP
CHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCC
YQEMQTLSLTGRPWDAFDSALIRGDKLIGVLTDREKTPATIAARMLEYGYDNYRMTVGEA
HHHHHEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEHHH
LGNGEEESVRTFSLEEASQSAFRFPNCLILQRNKVHPRPFGIPESEFHLLNGRNRMITKM
HCCCCCHHEEEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCEEHHH
PVRLLTLSMLTLREKKSFWDIGFCTGSVSIEAKLQFPELKVTAFEQRTEGKELMERNSRK
HHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEEEECCCEEEEEHHHHCCHHHHHHHCCCC
FGTPGITTVMGDFLETELGGLPAPDAVFIGGHGGKMIEILQKIKEVLLPDGVIVFNSVSE
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCH
ESKALFTKGITQINKKVTQCTRIAVDAFNPIEIMRAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]