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The map label for this gene is cbiHC [H]

Identifier: 150005595

GI number: 150005595

Start: 3897781

End: 3899187

Strand: Reverse

Name: cbiHC [H]

Synonym: BVU_3083

Alternate gene names: 150005595

Gene position: 3899187-3897781 (Counterclockwise)

Preceding gene: 150005596

Following gene: 150005594

Centisome position: 75.52

GC content: 47.69

Gene sequence:

>1407_bases
ATGAAAAAGGCCCAATTAATCGTAGCCGGCATTGGTCCCGGCTCACCCGAAGATATAACCCCCGCTGTAATACAAGCAGT
CAAGAACAGCGATGTAGTAATCGGCTATAAATACTATTTCCAGTTTATCGAACCCTATCTGGAACCGGGCACCGAATGTA
TAGACACCGGAATGAAACGTGAAAAAGCACGTGCCGAACAGGCTTTCGAGCTGGCGGAACAGGGAAAGACTGTATGCGTT
ATCAGCTCGGGAGATGCCGGAATTTATGGCATGGCTCCGCTGGTTTACGAAATGAAACGCGAGCGTGGCAGCCGGGTGGA
AATAGAAGTATTGCCGGGTATCAGTGCTTTTCAGAAAGCGGCTTCCCTGTTGGGAGCCCCCATCGGTCACGATTTCTGTG
TGATTTCCCTCTCCGACCTCATGACACCATGGGACCGGATTGAAAAACGCATCCATGCAGCCGCAACGGCAGATTTTGTA
ACGGCGGTCTATAATCCCAAAAGCGAAGGGCGGTATTGGCAACTCTACAGATTAAAAGAAATTTTTCTGAAAGAGCGTGA
CCCCGAAACTCCGGTAGGCTTTGTGCGTCAGGCCGGACGTAAGGAAGAAACCGTGACAATCACCACTTTGCAAGAGTTCG
ATCCCGAACAGGTGGATATGTTTACAGTGGTATTGATTGGCAACTCCCAATCTTATCATCAGGAAGGGAAATTAATCACT
CCACGTGGTTATTACCGGGAAAAGACCACCGATGCGACAGGAATCGGTCAGGAGATTATGATAAACAGTTTCCGTACTAT
TGAGAAAGAATTGAAAAATAAAAATATTCCTTCGGATCACAAATGGGCATTACTGCATGCCATCCATACCACAGCCGATT
TCGAGATGGAAAACATATTGCATATAGATCCTCTTGCCGTAGAATGTCTGTATAAAATATTGAATGAAGGAAAAGTACGT
ACAATTATTACGGATGTGACGATGGCTGCCGCGGGCATCCGTAAAGGTGCTTTGGAACGGATGGGCATCGGGGTGAAATG
CTATCTGGGTGACGAACGCGCGGCAGCATTGGCAAAAGAAAAAGGAATCACCCGTACACAGGCCGGTATACGTATGGCAG
CAGAGGAACATCCGGAAGCTTTATATGTATTCGGTAATGCCCCTACAGCATTGATGGAACTGTGTGACCTGATACGGAAA
GAAAAAGCGCATCCATGCGGCATCATCGCTGCTCCGGTGGGCTTTGTGCACGTTTGCGAAAGCAAACACATGGTGAAACC
TTTCAGCCACATCCCCAAACTGATAGTAGAAGGACGCAAAGGGGGAAGCAATCTGGCAGCGACTCTGGTAAATGCCATCC
TTACTTTTGATGATGCGGAACAACTGAAACCGGGAAGAGATGTATAA

Upstream 100 bases:

>100_bases
GTCAGGACAGCGCATTGTCATTCAGAGGATTATATTGGCTGAAAGCACTGAAGGAAACTTTTAAATCAGATTCCGGAAAG
GAATAATTATATAATAAAAA

Downstream 100 bases:

>100_bases
GTCCATGCAAACATTCTATATAATAGGTATAAGCGATAACCGGAATCAATTTCTTTCTCCTGAAATCCGGAACTTGGTTT
CTCAAGGGAAAGTCTTCTCG

Product: precorrin-3B C17-methyltransferase

Products: NA

Alternate protein names: Cobalt-precorrin-3B C(17)-methyltransferase; Cobalt-precorrin-3 methylase; Cobalt-precorrin-3 methyltransferase; Cobalt-precorrin-8X methylmutase; Cobalt-precorrin isomerase [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKKAQLIVAGIGPGSPEDITPAVIQAVKNSDVVIGYKYYFQFIEPYLEPGTECIDTGMKREKARAEQAFELAEQGKTVCV
ISSGDAGIYGMAPLVYEMKRERGSRVEIEVLPGISAFQKAASLLGAPIGHDFCVISLSDLMTPWDRIEKRIHAAATADFV
TAVYNPKSEGRYWQLYRLKEIFLKERDPETPVGFVRQAGRKEETVTITTLQEFDPEQVDMFTVVLIGNSQSYHQEGKLIT
PRGYYREKTTDATGIGQEIMINSFRTIEKELKNKNIPSDHKWALLHAIHTTADFEMENILHIDPLAVECLYKILNEGKVR
TIITDVTMAAAGIRKGALERMGIGVKCYLGDERAAALAKEKGITRTQAGIRMAAEEHPEALYVFGNAPTALMELCDLIRK
EKAHPCGIIAAPVGFVHVCESKHMVKPFSHIPKLIVEGRKGGSNLAATLVNAILTFDDAEQLKPGRDV

Sequences:

>Translated_468_residues
MKKAQLIVAGIGPGSPEDITPAVIQAVKNSDVVIGYKYYFQFIEPYLEPGTECIDTGMKREKARAEQAFELAEQGKTVCV
ISSGDAGIYGMAPLVYEMKRERGSRVEIEVLPGISAFQKAASLLGAPIGHDFCVISLSDLMTPWDRIEKRIHAAATADFV
TAVYNPKSEGRYWQLYRLKEIFLKERDPETPVGFVRQAGRKEETVTITTLQEFDPEQVDMFTVVLIGNSQSYHQEGKLIT
PRGYYREKTTDATGIGQEIMINSFRTIEKELKNKNIPSDHKWALLHAIHTTADFEMENILHIDPLAVECLYKILNEGKVR
TIITDVTMAAAGIRKGALERMGIGVKCYLGDERAAALAKEKGITRTQAGIRMAAEEHPEALYVFGNAPTALMELCDLIRK
EKAHPCGIIAAPVGFVHVCESKHMVKPFSHIPKLIVEGRKGGSNLAATLVNAILTFDDAEQLKPGRDV
>Mature_468_residues
MKKAQLIVAGIGPGSPEDITPAVIQAVKNSDVVIGYKYYFQFIEPYLEPGTECIDTGMKREKARAEQAFELAEQGKTVCV
ISSGDAGIYGMAPLVYEMKRERGSRVEIEVLPGISAFQKAASLLGAPIGHDFCVISLSDLMTPWDRIEKRIHAAATADFV
TAVYNPKSEGRYWQLYRLKEIFLKERDPETPVGFVRQAGRKEETVTITTLQEFDPEQVDMFTVVLIGNSQSYHQEGKLIT
PRGYYREKTTDATGIGQEIMINSFRTIEKELKNKNIPSDHKWALLHAIHTTADFEMENILHIDPLAVECLYKILNEGKVR
TIITDVTMAAAGIRKGALERMGIGVKCYLGDERAAALAKEKGITRTQAGIRMAAEEHPEALYVFGNAPTALMELCDLIRK
EKAHPCGIIAAPVGFVHVCESKHMVKPFSHIPKLIVEGRKGGSNLAATLVNAILTFDDAEQLKPGRDV

Specific function: Bifunctional enzyme with a methyltransferase domain that catalyzes the methylation of C-17 in cobalt-precorrin-3B to form cobalt-precorrin-4 and an isomerase domain that catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014422
- InterPro:   IPR003722
- InterPro:   IPR006363 [H]

Pfam domain/function: PF02570 CbiC; PF00590 TP_methylase [H]

EC number: NA

Molecular weight: Translated: 51794; Mature: 51794

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAQLIVAGIGPGSPEDITPAVIQAVKNSDVVIGYKYYFQFIEPYLEPGTECIDTGMKR
CCCCEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHH
EKARAEQAFELAEQGKTVCVISSGDAGIYGMAPLVYEMKRERGSRVEIEVLPGISAFQKA
HHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
ASLLGAPIGHDFCVISLSDLMTPWDRIEKRIHAAATADFVTAVYNPKSEGRYWQLYRLKE
HHHHCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEHHHHHH
IFLKERDPETPVGFVRQAGRKEETVTITTLQEFDPEQVDMFTVVLIGNSQSYHQEGKLIT
HHHHCCCCCCCHHHHHHCCCCCCEEEEEEHHHCCCCCCCEEEEEEEECCCCHHCCCCEEC
PRGYYREKTTDATGIGQEIMINSFRTIEKELKNKNIPSDHKWALLHAIHTTADFEMENIL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCCCCEE
HIDPLAVECLYKILNEGKVRTIITDVTMAAAGIRKGALERMGIGVKCYLGDERAAALAKE
EECHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHH
KGITRTQAGIRMAAEEHPEALYVFGNAPTALMELCDLIRKEKAHPCGIIAAPVGFVHVCE
CCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHC
SKHMVKPFSHIPKLIVEGRKGGSNLAATLVNAILTFDDAEQLKPGRDV
CCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MKKAQLIVAGIGPGSPEDITPAVIQAVKNSDVVIGYKYYFQFIEPYLEPGTECIDTGMKR
CCCCEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHH
EKARAEQAFELAEQGKTVCVISSGDAGIYGMAPLVYEMKRERGSRVEIEVLPGISAFQKA
HHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
ASLLGAPIGHDFCVISLSDLMTPWDRIEKRIHAAATADFVTAVYNPKSEGRYWQLYRLKE
HHHHCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEHHHHHH
IFLKERDPETPVGFVRQAGRKEETVTITTLQEFDPEQVDMFTVVLIGNSQSYHQEGKLIT
HHHHCCCCCCCHHHHHHCCCCCCEEEEEEHHHCCCCCCCEEEEEEEECCCCHHCCCCEEC
PRGYYREKTTDATGIGQEIMINSFRTIEKELKNKNIPSDHKWALLHAIHTTADFEMENIL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCCCCEE
HIDPLAVECLYKILNEGKVRTIITDVTMAAAGIRKGALERMGIGVKCYLGDERAAALAKE
EECHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHH
KGITRTQAGIRMAAEEHPEALYVFGNAPTALMELCDLIRKEKAHPCGIIAAPVGFVHVCE
CCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHC
SKHMVKPFSHIPKLIVEGRKGGSNLAATLVNAILTFDDAEQLKPGRDV
CCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]