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The map label for this gene is metA

Identifier: 150004585

GI number: 150004585

Start: 2644423

End: 2645340

Strand: Direct

Name: metA

Synonym: BVU_2042

Alternate gene names: 150004585

Gene position: 2644423-2645340 (Clockwise)

Preceding gene: 150004582

Following gene: 150004586

Centisome position: 51.22

GC content: 40.63

Gene sequence:

>918_bases
ATGCCGTTAAATTTACCCGATAAACTACCTGCTATTGAATTGCTGAAGGAGGAAAATATCTTCGTCATAGACAATTCACG
TGCCAGTGCACAGGATATTCGTCCGTTAAAAATCGTGATATTGAATTTGATGCCGTTGAAGATAACGACAGAAACGGATT
TGGTACGTTTGCTTTCCAACACTCCCTTGCAGTTGGAAATATCATTTATGAAGTTGAAAAGCCATACATCGAAAAATACG
CCGGTAGAACATATGAAAGCATTCTATCATGACTTTGATTTGATGCGCGACGAGAAATATGACGGGATGATTATTACGGG
AGCTCCGGTAGAGCAGATGCCGTATGAGGATGTGAATTATTGGGATGAGATTACTACTATTTTTGATTGGGCGCGTACTC
ATGTTACCTCAACTCTTTATATTTGTTGGGCGGCCCAAGCCGGGCTTTATCATTTCTATGGAGTTCCCAAATATCCGCTG
AAACAAAAAATGTTTGGTATTTTCCGTCATCATATCAATGTACAGGGATTGCCCATATTCCGTGGTTTTGATGATGAGTT
TTTTGTACCACATAGCCGTCATACCGAAATACACCGTGAGGATATTCTGAAAGTAAAAGAGTTGGCTTTAATAGCTGAGT
CTGATGAGTCTGGGGTTTATATGGCTATGGCTCGTAATGGGCGTGAATTCTTTATTACCGGGCATTCGGAGTATTCTCCT
TATACGCTTGATACGGAATATAAGCGTGATTTGGCGAAAGGGTTGCCTATTGAAATGCCTGTAAATTATTATAAGGACGA
TAATCCGGACAATGCCCCGGTGGTGCGTTGGCGCGGACATGCCAATTTGTTGTTTTCTAATTGGTTGAACTATTATGTAT
ATCAGGAAACCCCGTTTGATATAAATCAGATACGATGA

Upstream 100 bases:

>100_bases
ATCAGGGAAAGGAAATAATTTAGTTCAAAAGATCGTTTAATAAGGAGAATTGGCGGGATTTTTTTAATTTTGCACTTACA
ACTAATTAACAGATAAGAAA

Downstream 100 bases:

>100_bases
TCAGACAACGAAAAATAGAATTATTAGCTCCTGCTAAAAATCTGGAGTGCGGTATTGCAGCTGTTGATCACGGTGCTGAT
GCCATTTATATTGGTGCTCC

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPLNLPDKLPAIELLKEENIFVIDNSRASAQDIRPLKIVILNLMPLKITTETDLVRLLSNTPLQLEISFMKLKSHTSKNT
PVEHMKAFYHDFDLMRDEKYDGMIITGAPVEQMPYEDVNYWDEITTIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYPL
KQKMFGIFRHHINVQGLPIFRGFDDEFFVPHSRHTEIHREDILKVKELALIAESDESGVYMAMARNGREFFITGHSEYSP
YTLDTEYKRDLAKGLPIEMPVNYYKDDNPDNAPVVRWRGHANLLFSNWLNYYVYQETPFDINQIR

Sequences:

>Translated_305_residues
MPLNLPDKLPAIELLKEENIFVIDNSRASAQDIRPLKIVILNLMPLKITTETDLVRLLSNTPLQLEISFMKLKSHTSKNT
PVEHMKAFYHDFDLMRDEKYDGMIITGAPVEQMPYEDVNYWDEITTIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYPL
KQKMFGIFRHHINVQGLPIFRGFDDEFFVPHSRHTEIHREDILKVKELALIAESDESGVYMAMARNGREFFITGHSEYSP
YTLDTEYKRDLAKGLPIEMPVNYYKDDNPDNAPVVRWRGHANLLFSNWLNYYVYQETPFDINQIR
>Mature_304_residues
PLNLPDKLPAIELLKEENIFVIDNSRASAQDIRPLKIVILNLMPLKITTETDLVRLLSNTPLQLEISFMKLKSHTSKNTP
VEHMKAFYHDFDLMRDEKYDGMIITGAPVEQMPYEDVNYWDEITTIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYPLK
QKMFGIFRHHINVQGLPIFRGFDDEFFVPHSRHTEIHREDILKVKELALIAESDESGVYMAMARNGREFFITGHSEYSPY
TLDTEYKRDLAKGLPIEMPVNYYKDDNPDNAPVVRWRGHANLLFSNWLNYYVYQETPFDINQIR

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family

Homologues:

Organism=Escherichia coli, GI1790443, Length=304, Percent_Identity=46.7105263157895, Blast_Score=320, Evalue=6e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): META_BACV8 (A6L1Z3)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001299329.1
- ProteinModelPortal:   A6L1Z3
- SMR:   A6L1Z3
- STRING:   A6L1Z3
- GeneID:   5303007
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_2042
- NMPDR:   fig|435590.6.peg.1917
- eggNOG:   COG1897
- HOGENOM:   HBG362506
- OMA:   QAGLYYH
- ProtClustDB:   PRK05368
- GO:   GO:0005737
- HAMAP:   MF_00295
- InterPro:   IPR005697
- PANTHER:   PTHR20919
- PIRSF:   PIRSF000450
- ProDom:   PD037892
- TIGRFAMs:   TIGR01001

Pfam domain/function: PF04204 HTS

EC number: =2.3.1.46

Molecular weight: Translated: 35759; Mature: 35628

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: ACT_SITE 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNLPDKLPAIELLKEENIFVIDNSRASAQDIRPLKIVILNLMPLKITTETDLVRLLSN
CCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEEEEEEECHHHHHHHHCC
TPLQLEISFMKLKSHTSKNTPVEHMKAFYHDFDLMRDEKYDGMIITGAPVEQMPYEDVNY
CCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHCCCCCCCH
WDEITTIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYPLKQKMFGIFRHHINVQGLPIF
HHHHHHHHHHHHHHHHEEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCEEEE
RGFDDEFFVPHSRHTEIHREDILKVKELALIAESDESGVYMAMARNGREFFITGHSEYSP
ECCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCEEEEEECCCCEEEEECCCCCCC
YTLDTEYKRDLAKGLPIEMPVNYYKDDNPDNAPVVRWRGHANLLFSNWLNYYVYQETPFD
EEECHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEECCCCCEEEECCCEEEEEECCCCC
INQIR
HHCCC
>Mature Secondary Structure 
PLNLPDKLPAIELLKEENIFVIDNSRASAQDIRPLKIVILNLMPLKITTETDLVRLLSN
CCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEEEEEEECHHHHHHHHCC
TPLQLEISFMKLKSHTSKNTPVEHMKAFYHDFDLMRDEKYDGMIITGAPVEQMPYEDVNY
CCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHCCCCCCCH
WDEITTIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYPLKQKMFGIFRHHINVQGLPIF
HHHHHHHHHHHHHHHHEEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCEEEE
RGFDDEFFVPHSRHTEIHREDILKVKELALIAESDESGVYMAMARNGREFFITGHSEYSP
ECCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCEEEEEECCCCEEEEECCCCCCC
YTLDTEYKRDLAKGLPIEMPVNYYKDDNPDNAPVVRWRGHANLLFSNWLNYYVYQETPFD
EEECHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEECCCCCEEEECCCEEEEEECCCCC
INQIR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA