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The map label for this gene is nfnB [C]

Identifier: 150004582

GI number: 150004582

Start: 2641382

End: 2642110

Strand: Direct

Name: nfnB [C]

Synonym: BVU_2039

Alternate gene names: 150004582

Gene position: 2641382-2642110 (Clockwise)

Preceding gene: 150004581

Following gene: 150004585

Centisome position: 51.16

GC content: 44.99

Gene sequence:

>729_bases
ATGAATTTAGAAGAGGTATTGAACTTCCGCCGGTCTGTGCGGAGGTATGATAAAAATAAACCGATAGACCCGGAAAAGGT
GAAACATTGTCTTGAACTGGCTACGCTGGCTCCCAATAGTTCCAATATGCAATTGTGGGAATTTTATCAAATAACGAATC
CCGGACTGATGGCGAAAGTTTCAGAAGCTTGTTTAGGGCAGTCGGCTGCTTCTACGGCTTCGGAAATTGTTGTTTTTGTT
ACTCGTCAGGATTTGTATAAAAAGCGTGCTAAATTTGTGCTTGACTTTGAAGAAGGAAATATCAGGCGCAATAGTCCGAA
AGAGCGTCAGGAAAAACGTATTAGGGACAGGAAGCTGTATTATGGTAAACTGATGCCTTTCATTTATGCAAGGTTTTTCG
GGCTTCTAGGGCTTTTCAGGGTGATATTGGCGAGAACCATCAGCCTGTTCCGCCCTATGATGCTGGAAGTTTCGGAATGC
GATATGCGTGTGACGGTAAATAAATCCTGTGCCCTTGCTGCCCAAACCTTTATGATTGCCATGGCAAACGAAGGCTATGA
CACTTGTCCGCTGGAAGGTTTTGACAGCAGGCGGATGAAGAAACTATTGAAGCTGCCCCATGGGGCAGGCATCAATATGG
TTATACCTTGCGGCATACGGGATGGGAACAAAGGCATTTGGGGAGAACGGGGCAGGGTTCCTTTCGATGAAATCTATCAT
AGGATATAA

Upstream 100 bases:

>100_bases
TAATCTGTTTACCGGAGAGAATCCGTTCAGTTCCAAGAAAATGGCAGAAGTCATCCTGCAATGTTTCAGTAAGAAATAAA
GTTATTAATTTGAATAGGAA

Downstream 100 bases:

>100_bases
GAGAACAGGGTATTCCTGGCGGGTGATGAAGGTGTATTCCCTTAGATATTCCATCAGCATGCCGAATCGCTCTTCCTGAG
TGTGCTTGGAAGAAGACGTC

Product: putative nitroreductase

Products: NAD(P)(+); @TETR01.txt*5,6,7,8-Tetrahydropteridine!. [C]

Alternate protein names: NAD(P)H-Flavin Oxidoreductase; Nitroreductase Family Protein; NADPH Nitroreductase Protein; Nitrorecductase; NADph Nitroreductase Protein

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNLEEVLNFRRSVRRYDKNKPIDPEKVKHCLELATLAPNSSNMQLWEFYQITNPGLMAKVSEACLGQSAASTASEIVVFV
TRQDLYKKRAKFVLDFEEGNIRRNSPKERQEKRIRDRKLYYGKLMPFIYARFFGLLGLFRVILARTISLFRPMMLEVSEC
DMRVTVNKSCALAAQTFMIAMANEGYDTCPLEGFDSRRMKKLLKLPHGAGINMVIPCGIRDGNKGIWGERGRVPFDEIYH
RI

Sequences:

>Translated_242_residues
MNLEEVLNFRRSVRRYDKNKPIDPEKVKHCLELATLAPNSSNMQLWEFYQITNPGLMAKVSEACLGQSAASTASEIVVFV
TRQDLYKKRAKFVLDFEEGNIRRNSPKERQEKRIRDRKLYYGKLMPFIYARFFGLLGLFRVILARTISLFRPMMLEVSEC
DMRVTVNKSCALAAQTFMIAMANEGYDTCPLEGFDSRRMKKLLKLPHGAGINMVIPCGIRDGNKGIWGERGRVPFDEIYH
RI
>Mature_242_residues
MNLEEVLNFRRSVRRYDKNKPIDPEKVKHCLELATLAPNSSNMQLWEFYQITNPGLMAKVSEACLGQSAASTASEIVVFV
TRQDLYKKRAKFVLDFEEGNIRRNSPKERQEKRIRDRKLYYGKLMPFIYARFFGLLGLFRVILARTISLFRPMMLEVSEC
DMRVTVNKSCALAAQTFMIAMANEGYDTCPLEGFDSRRMKKLLKLPHGAGINMVIPCGIRDGNKGIWGERGRVPFDEIYH
RI

Specific function: Reduction Of A Variety Of Nitroaromatic Compounds Using NADH (And To Lesser Extent Nadph) As Source Of Reducing Equivalents; Two Electrons Are Transferred. Capable Of Reducing Nitrofurazone, Quinones And The Anti-Tumor Agent Cb1954 (5- (Aziridin-1-Yl)-2,4

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27941; Mature: 27941

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEEVLNFRRSVRRYDKNKPIDPEKVKHCLELATLAPNSSNMQLWEFYQITNPGLMAKV
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHH
SEACLGQSAASTASEIVVFVTRQDLYKKRAKFVLDFEEGNIRRNSPKERQEKRIRDRKLY
HHHHHCCHHHCCHHHEEEEEEHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHH
YGKLMPFIYARFFGLLGLFRVILARTISLFRPMMLEVSECDMRVTVNKSCALAAQTFMIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHH
MANEGYDTCPLEGFDSRRMKKLLKLPHGAGINMVIPCGIRDGNKGIWGERGRVPFDEIYH
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHH
RI
CC
>Mature Secondary Structure
MNLEEVLNFRRSVRRYDKNKPIDPEKVKHCLELATLAPNSSNMQLWEFYQITNPGLMAKV
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHH
SEACLGQSAASTASEIVVFVTRQDLYKKRAKFVLDFEEGNIRRNSPKERQEKRIRDRKLY
HHHHHCCHHHCCHHHEEEEEEHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHH
YGKLMPFIYARFFGLLGLFRVILARTISLFRPMMLEVSECDMRVTVNKSCALAAQTFMIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHH
MANEGYDTCPLEGFDSRRMKKLLKLPHGAGINMVIPCGIRDGNKGIWGERGRVPFDEIYH
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHH
RI
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H; 6,7-Dihydropteridine [C]

Specific reaction: NAD(P)H + 6,7-Dihydropteridine = NAD(P)(+) + @TETR01.txt*5,6,7,8-Tetrahydropteridine!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA