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The map label for this gene is gpmA [H]

Identifier: 150004448

GI number: 150004448

Start: 2468117

End: 2468878

Strand: Reverse

Name: gpmA [H]

Synonym: BVU_1895

Alternate gene names: 150004448

Gene position: 2468878-2468117 (Counterclockwise)

Preceding gene: 150004450

Following gene: 150004447

Centisome position: 47.82

GC content: 39.5

Gene sequence:

>762_bases
ATGAAAAGAATCGTATTACTCCGCCATGGAGAAAGTACTTGGAACAAAGACAACCGTTTTACAGGATGGACAGATGTAGA
TTTAACCGAAAAAGGTATCGCTGATGCCAACCAAGCAGGTATACTCTTAAAAGAAAAAGGATTTCATTTTGATAAAGCTT
ACACTTCTTTTTTAAAGCGTGCGGTCAAAACATTAAACTGTGTCCTAGATAAAATGGATCAAGACTGGATACCTGTAGAG
AAAAGTTGGCGCCTAAATGAGAAACATTATGGCGCATTGCAAGGATTAAACAAAAGCGAAACAGCTTCTAAATACGGAGA
AGAACAAGTCTTGATATGGCGCCGTAGTTTTAACGTAGCCCCCAATGCCCTACCGGAAGATGATCCGCGCAATCCGAAAA
CAGATACCCGTTATAAAGAAGTTCCTGACAAAGATCTTCCACGTACCGAATCTCTGAAAGAAACAGTAGAACGTATATTA
CCTTATTGGAAATGCATCATCTTCCCCAATCTAGCTACAGCAAACGAACTGCTGGTAGTAGCTCACGGAAACAGCCTCAG
AGGAATTATTAAATATTTGAAACATATACCGGATGAGGAAATTGTAGGTCTTAATCTACCTACTGCTGTTCCGTATGTAT
TCGAGTTTGATAATGACCTGAATTTGAAGAAAGACTACTTTTTGGGAGATCCGGAAAAAATAAAAAAACTAATGGAAGCT
GTAGCCGATCAAGGAAAAACCAACCCCGGTGGCAGGAAATAA

Upstream 100 bases:

>100_bases
GTTAAATTCATAATTAATGGGTATTGATAAGTATGTATGCTACAACTAATTTTGCCGCCAACAGAAAATGTATTACCGGG
TAATAAAGAAAGGAGAACAA

Downstream 100 bases:

>100_bases
TTTTCCTGCGCTGTCCGAAACCTCCATCACAGAATGGAGAATACATCAAAATAGTGTTTTCAATAGTGCATTCAAACGCA
ATCATACGCTTTTATACTAG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MKRIVLLRHGESTWNKDNRFTGWTDVDLTEKGIADANQAGILLKEKGFHFDKAYTSFLKRAVKTLNCVLDKMDQDWIPVE
KSWRLNEKHYGALQGLNKSETASKYGEEQVLIWRRSFNVAPNALPEDDPRNPKTDTRYKEVPDKDLPRTESLKETVERIL
PYWKCIIFPNLATANELLVVAHGNSLRGIIKYLKHIPDEEIVGLNLPTAVPYVFEFDNDLNLKKDYFLGDPEKIKKLMEA
VADQGKTNPGGRK

Sequences:

>Translated_253_residues
MKRIVLLRHGESTWNKDNRFTGWTDVDLTEKGIADANQAGILLKEKGFHFDKAYTSFLKRAVKTLNCVLDKMDQDWIPVE
KSWRLNEKHYGALQGLNKSETASKYGEEQVLIWRRSFNVAPNALPEDDPRNPKTDTRYKEVPDKDLPRTESLKETVERIL
PYWKCIIFPNLATANELLVVAHGNSLRGIIKYLKHIPDEEIVGLNLPTAVPYVFEFDNDLNLKKDYFLGDPEKIKKLMEA
VADQGKTNPGGRK
>Mature_253_residues
MKRIVLLRHGESTWNKDNRFTGWTDVDLTEKGIADANQAGILLKEKGFHFDKAYTSFLKRAVKTLNCVLDKMDQDWIPVE
KSWRLNEKHYGALQGLNKSETASKYGEEQVLIWRRSFNVAPNALPEDDPRNPKTDTRYKEVPDKDLPRTESLKETVERIL
PYWKCIIFPNLATANELLVVAHGNSLRGIIKYLKHIPDEEIVGLNLPTAVPYVFEFDNDLNLKKDYFLGDPEKIKKLMEA
VADQGKTNPGGRK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=248, Percent_Identity=50, Blast_Score=260, Evalue=7e-70,
Organism=Homo sapiens, GI4505753, Length=248, Percent_Identity=50.4032258064516, Blast_Score=253, Evalue=1e-67,
Organism=Homo sapiens, GI71274132, Length=248, Percent_Identity=48.3870967741936, Blast_Score=237, Evalue=8e-63,
Organism=Homo sapiens, GI4502445, Length=250, Percent_Identity=46, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI40353764, Length=250, Percent_Identity=46, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=51.5527950310559, Blast_Score=170, Evalue=1e-42,
Organism=Escherichia coli, GI1786970, Length=247, Percent_Identity=56.2753036437247, Blast_Score=295, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=49.1869918699187, Blast_Score=239, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6324516, Length=300, Percent_Identity=31, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320183, Length=301, Percent_Identity=29.2358803986711, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6324857, Length=214, Percent_Identity=27.5700934579439, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646216, Length=249, Percent_Identity=50.2008032128514, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI85725270, Length=249, Percent_Identity=49.3975903614458, Blast_Score=243, Evalue=6e-65,
Organism=Drosophila melanogaster, GI85725272, Length=249, Percent_Identity=49.3975903614458, Blast_Score=243, Evalue=6e-65,
Organism=Drosophila melanogaster, GI24650981, Length=249, Percent_Identity=49.3975903614458, Blast_Score=243, Evalue=6e-65,
Organism=Drosophila melanogaster, GI24648979, Length=252, Percent_Identity=35.3174603174603, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI28571817, Length=252, Percent_Identity=35.3174603174603, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI28571815, Length=252, Percent_Identity=35.3174603174603, Blast_Score=160, Evalue=6e-40,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 29056; Mature: 29056

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIVLLRHGESTWNKDNRFTGWTDVDLTEKGIADANQAGILLKEKGFHFDKAYTSFLKR
CCEEEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEEEECCCCCHHHHHHHHHHH
AVKTLNCVLDKMDQDWIPVEKSWRLNEKHYGALQGLNKSETASKYGEEQVLIWRRSFNVA
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCCCC
PNALPEDDPRNPKTDTRYKEVPDKDLPRTESLKETVERILPYWKCIIFPNLATANELLVV
CCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
AHGNSLRGIIKYLKHIPDEEIVGLNLPTAVPYVFEFDNDLNLKKDYFLGDPEKIKKLMEA
ECCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHH
VADQGKTNPGGRK
HHHCCCCCCCCCC
>Mature Secondary Structure
MKRIVLLRHGESTWNKDNRFTGWTDVDLTEKGIADANQAGILLKEKGFHFDKAYTSFLKR
CCEEEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEEEECCCCCHHHHHHHHHHH
AVKTLNCVLDKMDQDWIPVEKSWRLNEKHYGALQGLNKSETASKYGEEQVLIWRRSFNVA
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCCCC
PNALPEDDPRNPKTDTRYKEVPDKDLPRTESLKETVERILPYWKCIIFPNLATANELLVV
CCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
AHGNSLRGIIKYLKHIPDEEIVGLNLPTAVPYVFEFDNDLNLKKDYFLGDPEKIKKLMEA
ECCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHH
VADQGKTNPGGRK
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA