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The map label for this gene is dinB [H]

Identifier: 150004450

GI number: 150004450

Start: 2469811

End: 2470866

Strand: Reverse

Name: dinB [H]

Synonym: BVU_1897

Alternate gene names: 150004450

Gene position: 2470866-2469811 (Counterclockwise)

Preceding gene: 150004451

Following gene: 150004448

Centisome position: 47.86

GC content: 41.19

Gene sequence:

>1056_bases
ATGGATGCATTCTACGCATCGGTAGAACAGCGTGACAACCCCGAATTATGTGGAAAACCGCTTGCTGTGGGACACGCTGA
AGAACGAGGTGTGGTAGCTGCTGCCAGTTACGAAGCCCGTCGTTACGGAGTACATTCCGCCATGTCATCACAAAAAGCCA
AAAGACTTTGCCCAGAACTGATTTTTGTTCCAGGGCGGATGAATGTATATAAAGCTGTATCCCGGCAGATACACGATATC
TTTCATACCTATACAGATATCATAGAGCCTCTGTCACTAGACGAAGCCTTTCTGGATGTAACTGAAAATAAAGCAGGCTT
TTCACTTGCTATAGATATAGCCAAAGATATAAAAAAGCGTATCCGCAAAGAATTGGGATTGATAGCTTCAGCCGGGGTCT
CTTATAACAAATTTCTAGCCAAAATAGCATCGGATTACCGCAAACCCGACGGATTATGTACAATACATCCCGACCAAGCA
TTGGATTTCATCGCCCATCTTCCCATCGAATCTTTTTGGGGAGTAGGTCCGGTCACAGCCCAAAAAATGCACGCATTAGG
TATTCATAATGGTACCCAATTACAAGCCTGCACTTTAGAAATGCTTACCCGACAGTTTGGCAAAGCAGGTAATCTATATT
ACGATTTTGCACGAGGCATAGACCTCCGTCCTGTAGAACCCATAAGAATCCGTAAGTCCGTAGGATGCGAACATACATTG
GAAAAAGACATTTCTCTTCATTCTTCCGCCATCATTGAACTATATCATGTAGTCACCGAATTGCTAGAAAGACTGAAACG
CACTAATTTCAGTGGTAATACACTTACTTTAAAAATAAAATTCCATGACTTTAACCAAATAACCCGCAGCATCACTCAAG
ACAGTGAACTGACAAGCATGGATAAAATTCTTCCTTTAGCAAAAAAATTACTGAAAGAAATTGATTATGAAAGCCACCCC
ATCCGCCTTATCGGACTATCCGTATCTAATCCAAAAGAAGAAATAAAAAAACAATGGGAACAACTTTCATTGGAATTTAA
AGAGTGGGATGATTAA

Upstream 100 bases:

>100_bases
AAATAAAGCTGTTAAAGAACTCATCAACCAAAAACCTTTTTCATACCTTTGCTCTACAAATTTCATGAAGATGTCCGAAC
GCAAAATAATACATATCGAT

Downstream 100 bases:

>100_bases
GGTACTGGATAAATGAATCAATATAAGATTCCATTGTTTCAAACCCTTTCACTCCATTCTTTAATTCTAATCCATAATAT
ATTCCCGCCAGCAAACCTGT

Product: DNA damage-inducible protein

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MDAFYASVEQRDNPELCGKPLAVGHAEERGVVAAASYEARRYGVHSAMSSQKAKRLCPELIFVPGRMNVYKAVSRQIHDI
FHTYTDIIEPLSLDEAFLDVTENKAGFSLAIDIAKDIKKRIRKELGLIASAGVSYNKFLAKIASDYRKPDGLCTIHPDQA
LDFIAHLPIESFWGVGPVTAQKMHALGIHNGTQLQACTLEMLTRQFGKAGNLYYDFARGIDLRPVEPIRIRKSVGCEHTL
EKDISLHSSAIIELYHVVTELLERLKRTNFSGNTLTLKIKFHDFNQITRSITQDSELTSMDKILPLAKKLLKEIDYESHP
IRLIGLSVSNPKEEIKKQWEQLSLEFKEWDD

Sequences:

>Translated_351_residues
MDAFYASVEQRDNPELCGKPLAVGHAEERGVVAAASYEARRYGVHSAMSSQKAKRLCPELIFVPGRMNVYKAVSRQIHDI
FHTYTDIIEPLSLDEAFLDVTENKAGFSLAIDIAKDIKKRIRKELGLIASAGVSYNKFLAKIASDYRKPDGLCTIHPDQA
LDFIAHLPIESFWGVGPVTAQKMHALGIHNGTQLQACTLEMLTRQFGKAGNLYYDFARGIDLRPVEPIRIRKSVGCEHTL
EKDISLHSSAIIELYHVVTELLERLKRTNFSGNTLTLKIKFHDFNQITRSITQDSELTSMDKILPLAKKLLKEIDYESHP
IRLIGLSVSNPKEEIKKQWEQLSLEFKEWDD
>Mature_351_residues
MDAFYASVEQRDNPELCGKPLAVGHAEERGVVAAASYEARRYGVHSAMSSQKAKRLCPELIFVPGRMNVYKAVSRQIHDI
FHTYTDIIEPLSLDEAFLDVTENKAGFSLAIDIAKDIKKRIRKELGLIASAGVSYNKFLAKIASDYRKPDGLCTIHPDQA
LDFIAHLPIESFWGVGPVTAQKMHALGIHNGTQLQACTLEMLTRQFGKAGNLYYDFARGIDLRPVEPIRIRKSVGCEHTL
EKDISLHSSAIIELYHVVTELLERLKRTNFSGNTLTLKIKFHDFNQITRSITQDSELTSMDKILPLAKKLLKEIDYESHP
IRLIGLSVSNPKEEIKKQWEQLSLEFKEWDD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=333, Percent_Identity=31.8318318318318, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI7706681, Length=253, Percent_Identity=35.9683794466403, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI5729982, Length=342, Percent_Identity=28.0701754385965, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI154350220, Length=243, Percent_Identity=30.0411522633745, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI7705344, Length=102, Percent_Identity=49.0196078431373, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1786425, Length=344, Percent_Identity=42.1511627906977, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1787432, Length=215, Percent_Identity=26.5116279069767, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193205700, Length=399, Percent_Identity=26.5664160401003, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17537959, Length=364, Percent_Identity=24.4505494505494, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI193205702, Length=347, Percent_Identity=24.207492795389, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115534089, Length=115, Percent_Identity=39.1304347826087, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI19923006, Length=334, Percent_Identity=27.8443113772455, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355641, Length=303, Percent_Identity=27.3927392739274, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24644984, Length=303, Percent_Identity=27.3927392739274, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24668444, Length=111, Percent_Identity=34.2342342342342, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39694; Mature: 39694

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAFYASVEQRDNPELCGKPLAVGHAEERGVVAAASYEARRYGVHSAMSSQKAKRLCPEL
CCCHHHHHHCCCCHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCHHH
IFVPGRMNVYKAVSRQIHDIFHTYTDIIEPLSLDEAFLDVTENKAGFSLAIDIAKDIKKR
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEHHHHHHHHHH
IRKELGLIASAGVSYNKFLAKIASDYRKPDGLCTIHPDQALDFIAHLPIESFWGVGPVTA
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHHHHCCCCCCHH
QKMHALGIHNGTQLQACTLEMLTRQFGKAGNLYYDFARGIDLRPVEPIRIRKSVGCEHTL
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCHHHHHHHCCCHHHH
EKDISLHSSAIIELYHVVTELLERLKRTNFSGNTLTLKIKFHDFNQITRSITQDSELTSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHCCHHHHHH
DKILPLAKKLLKEIDYESHPIRLIGLSVSNPKEEIKKQWEQLSLEFKEWDD
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHCCCC
>Mature Secondary Structure
MDAFYASVEQRDNPELCGKPLAVGHAEERGVVAAASYEARRYGVHSAMSSQKAKRLCPEL
CCCHHHHHHCCCCHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCHHH
IFVPGRMNVYKAVSRQIHDIFHTYTDIIEPLSLDEAFLDVTENKAGFSLAIDIAKDIKKR
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEHHHHHHHHHH
IRKELGLIASAGVSYNKFLAKIASDYRKPDGLCTIHPDQALDFIAHLPIESFWGVGPVTA
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHHHHCCCCCCHH
QKMHALGIHNGTQLQACTLEMLTRQFGKAGNLYYDFARGIDLRPVEPIRIRKSVGCEHTL
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCHHHHHHHCCCHHHH
EKDISLHSSAIIELYHVVTELLERLKRTNFSGNTLTLKIKFHDFNQITRSITQDSELTSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHCCHHHHHH
DKILPLAKKLLKEIDYESHPIRLIGLSVSNPKEEIKKQWEQLSLEFKEWDD
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA