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The map label for this gene is nuoC

Identifier: 150004311

GI number: 150004311

Start: 2254036

End: 2255595

Strand: Reverse

Name: nuoC

Synonym: BVU_1757

Alternate gene names: 150004311

Gene position: 2255595-2254036 (Counterclockwise)

Preceding gene: 150004312

Following gene: 150004310

Centisome position: 43.69

GC content: 44.55

Gene sequence:

>1560_bases
ATGAGTGAAAGAATAGAAATACCTGCCGAAAAGCTACATGAAGAAATGCTGAAATTGCGGCAGGGTAAACATATGGATTT
TCTACGCAGCCTTACCGGAATGGACTGGGGCGAAGAAGGACTAGGTGTAGTCTATCATCTGGAAGATACGAATACAAGAG
AAAATATAGTGGTCAGCACTCGCACAACCAACCGAGAAAAGCCGGAACTTCCTAGTGTAAGTGATATTTGGAAAGGTGCT
GAATTCAATGAACGCGAAGTGTACGACTATTATGGTATCCGCTTTATAGGACATCCTGATATGCGCCGTTTGTTCCTGCG
TGATGACTGGGTAGGCTATCCATTGCGTAAGGACTACGATGAAAGCCTCAACCCACTCCGTATGACCAATGAGGAACCTG
TAGACACGACACAATATATAGAAGTACAACATGATGGCAGTGTAATAGAAAAACGCGAAACCATTTTTGATGAGGACGAA
TATATCATTAACATAGGTCCTCAACATCCGGCAACCCACGGTGTACTTCGTTTTCGTGTTTCACTGGAAGGTGAGATTAT
CAAAAAACTGGATGTGCACTGCGGATACATCCATCGAGGTATCGAAAAAATGTGCGAAAGTCTTACCTATCCCCAAACCT
TGGCCCTGACCGACCGTTTGGATTATTTAGGTGCGCACCAAAACCGCCATGCTCTCTGTATGTGCATTGAACAGGCAATG
GGCGTAGAAGTAAGCGAACGGGTACAATACATTCGTACCATTATGGACGAATTGCAACGTATAGATTCTCACTTGCTTTT
CTTCTCCTGTCTCTGTATGGATATGGGTGCCTTGACCGCATTCTTCTATGGATTCCGTGATCGTGAGAAGATATTGGATA
TCTTCGAAGCAACTACCGGAGGACGTTTGATACAGAATTATAACACCATTGGAGGGGTACAAGCTGATATCGCTCCGGAC
TTTGTACAGAAAGTAAAAGAATTCATTGCTTATCTGCGTCCGATGCTAAAAGAATACCATGAAGTATTCACCGGAAATGT
CATTGCCCAAGAACGTTTGAAAGGTGTGGGAGTTCTTTCACGGGAAGATGCCATCTCTTTCGGAGCGACAGGAGGTACAG
GACGCGCCAGCGGTTGGGCATGCGATGTCCGCAAGCGTCATCCCTATGCGATGTATGGCAAGGTAGATTTTAAAGAGATT
GTCCACACTGAAGGTGACTGCTTTGCACGTTATATGGTCCGTATGGAAGAAATACTGGAAAGTATGGATATCATTGAGCA
ACTGATAGACAATATTCCTGAAGGGAACTATCAGGAAAAGATGAAACCGATTATACGTGTGCCCGAAGGGAATTATTATG
CCGCAGTGGAAGGTTCTCGCGGAGAGTTCGGTGTTTATCTGGAAAGTCGTGGAGACAAATTTCCTTACCGCATGAAATTC
CGCGCTACCGGTTTGCCTTTAGTATCAGCAATGGAAACTATGTGCCGCAACGCAAAAATTGCCGACTTAATTGCTATTGG
TGGAACGGTGGATTATGTAGTACCGGATATTGACCGATAA

Upstream 100 bases:

>100_bases
TGTTGTACGGCATGATACAATTGCAACGTAAAGTAAAACTGGAAAAATTCTTCGGCGGAGTGAACCGCAAAGAAAATGAA
CCACAAAATCCCGAACAAGC

Downstream 100 bases:

>100_bases
TAATGTGCCGATTCTTCAATATACAATTTGGAGAATGCACTATTTATCAGACTGAGAATTAACAAATTAAATAATTACAA
GTTTGCCTATTGGCAAATTA

Product: NADH dehydrogenase I, chain D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C/D; NDH-1 subunit C/D

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MSERIEIPAEKLHEEMLKLRQGKHMDFLRSLTGMDWGEEGLGVVYHLEDTNTRENIVVSTRTTNREKPELPSVSDIWKGA
EFNEREVYDYYGIRFIGHPDMRRLFLRDDWVGYPLRKDYDESLNPLRMTNEEPVDTTQYIEVQHDGSVIEKRETIFDEDE
YIINIGPQHPATHGVLRFRVSLEGEIIKKLDVHCGYIHRGIEKMCESLTYPQTLALTDRLDYLGAHQNRHALCMCIEQAM
GVEVSERVQYIRTIMDELQRIDSHLLFFSCLCMDMGALTAFFYGFRDREKILDIFEATTGGRLIQNYNTIGGVQADIAPD
FVQKVKEFIAYLRPMLKEYHEVFTGNVIAQERLKGVGVLSREDAISFGATGGTGRASGWACDVRKRHPYAMYGKVDFKEI
VHTEGDCFARYMVRMEEILESMDIIEQLIDNIPEGNYQEKMKPIIRVPEGNYYAAVEGSRGEFGVYLESRGDKFPYRMKF
RATGLPLVSAMETMCRNAKIADLIAIGGTVDYVVPDIDR

Sequences:

>Translated_519_residues
MSERIEIPAEKLHEEMLKLRQGKHMDFLRSLTGMDWGEEGLGVVYHLEDTNTRENIVVSTRTTNREKPELPSVSDIWKGA
EFNEREVYDYYGIRFIGHPDMRRLFLRDDWVGYPLRKDYDESLNPLRMTNEEPVDTTQYIEVQHDGSVIEKRETIFDEDE
YIINIGPQHPATHGVLRFRVSLEGEIIKKLDVHCGYIHRGIEKMCESLTYPQTLALTDRLDYLGAHQNRHALCMCIEQAM
GVEVSERVQYIRTIMDELQRIDSHLLFFSCLCMDMGALTAFFYGFRDREKILDIFEATTGGRLIQNYNTIGGVQADIAPD
FVQKVKEFIAYLRPMLKEYHEVFTGNVIAQERLKGVGVLSREDAISFGATGGTGRASGWACDVRKRHPYAMYGKVDFKEI
VHTEGDCFARYMVRMEEILESMDIIEQLIDNIPEGNYQEKMKPIIRVPEGNYYAAVEGSRGEFGVYLESRGDKFPYRMKF
RATGLPLVSAMETMCRNAKIADLIAIGGTVDYVVPDIDR
>Mature_518_residues
SERIEIPAEKLHEEMLKLRQGKHMDFLRSLTGMDWGEEGLGVVYHLEDTNTRENIVVSTRTTNREKPELPSVSDIWKGAE
FNEREVYDYYGIRFIGHPDMRRLFLRDDWVGYPLRKDYDESLNPLRMTNEEPVDTTQYIEVQHDGSVIEKRETIFDEDEY
IINIGPQHPATHGVLRFRVSLEGEIIKKLDVHCGYIHRGIEKMCESLTYPQTLALTDRLDYLGAHQNRHALCMCIEQAMG
VEVSERVQYIRTIMDELQRIDSHLLFFSCLCMDMGALTAFFYGFRDREKILDIFEATTGGRLIQNYNTIGGVQADIAPDF
VQKVKEFIAYLRPMLKEYHEVFTGNVIAQERLKGVGVLSREDAISFGATGGTGRASGWACDVRKRHPYAMYGKVDFKEIV
HTEGDCFARYMVRMEEILESMDIIEQLIDNIPEGNYQEKMKPIIRVPEGNYYAAVEGSRGEFGVYLESRGDKFPYRMKFR
ATGLPLVSAMETMCRNAKIADLIAIGGTVDYVVPDIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=382, Percent_Identity=35.8638743455497, Blast_Score=256, Evalue=4e-68,
Organism=Homo sapiens, GI260898743, Length=372, Percent_Identity=35.752688172043, Blast_Score=249, Evalue=4e-66,
Organism=Escherichia coli, GI145693162, Length=513, Percent_Identity=31.5789473684211, Blast_Score=284, Evalue=9e-78,
Organism=Escherichia coli, GI1789076, Length=513, Percent_Identity=30.7992202729045, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1788832, Length=488, Percent_Identity=29.7131147540984, Blast_Score=189, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17568379, Length=430, Percent_Identity=34.4186046511628, Blast_Score=268, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI17555284, Length=395, Percent_Identity=35.9493670886076, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI32563621, Length=118, Percent_Identity=38.135593220339, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71990788, Length=118, Percent_Identity=38.135593220339, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221459469, Length=383, Percent_Identity=39.1644908616188, Blast_Score=277, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24638644, Length=382, Percent_Identity=36.9109947643979, Blast_Score=271, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOCD_BACV8 (A6L169)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001299055.1
- ProteinModelPortal:   A6L169
- STRING:   A6L169
- GeneID:   5302723
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1757
- NMPDR:   fig|435590.6.peg.1654
- eggNOG:   COG0649
- HOGENOM:   HBG459705
- OMA:   MADVITI
- ProtClustDB:   CLSK823772
- GO:   GO:0006810
- HAMAP:   MF_01397
- InterPro:   IPR001135
- InterPro:   IPR001268
- InterPro:   IPR022885
- ProDom:   PD001581

Pfam domain/function: PF00329 Complex1_30kDa; PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 59741; Mature: 59610

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00542 COMPLEX1_30K; PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERIEIPAEKLHEEMLKLRQGKHMDFLRSLTGMDWGEEGLGVVYHLEDTNTRENIVVST
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEEEE
RTTNREKPELPSVSDIWKGAEFNEREVYDYYGIRFIGHPDMRRLFLRDDWVGYPLRKDYD
CCCCCCCCCCCCHHHHHCCCCCCCCEEEHHHCEEEECCHHHHHHHHHCCCCCCCCCCCHH
ESLNPLRMTNEEPVDTTQYIEVQHDGSVIEKRETIFDEDEYIINIGPQHPATHGVLRFRV
HCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEE
SLEGEIIKKLDVHCGYIHRGIEKMCESLTYPQTLALTDRLDYLGAHQNRHALCMCIEQAM
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GVEVSERVQYIRTIMDELQRIDSHLLFFSCLCMDMGALTAFFYGFRDREKILDIFEATTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
GRLIQNYNTIGGVQADIAPDFVQKVKEFIAYLRPMLKEYHEVFTGNVIAQERLKGVGVLS
CHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
REDAISFGATGGTGRASGWACDVRKRHPYAMYGKVDFKEIVHTEGDCFARYMVRMEEILE
CCCCCEECCCCCCCCCCCEEEECCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHH
SMDIIEQLIDNIPEGNYQEKMKPIIRVPEGNYYAAVEGSRGEFGVYLESRGDKFPYRMKF
HHHHHHHHHHHCCCCCHHHHCCCEEECCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEE
RATGLPLVSAMETMCRNAKIADLIAIGGTVDYVVPDIDR
EECCCHHHHHHHHHHCCCCHHHHEEECCEEEEECCCCCC
>Mature Secondary Structure 
SERIEIPAEKLHEEMLKLRQGKHMDFLRSLTGMDWGEEGLGVVYHLEDTNTRENIVVST
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEEEE
RTTNREKPELPSVSDIWKGAEFNEREVYDYYGIRFIGHPDMRRLFLRDDWVGYPLRKDYD
CCCCCCCCCCCCHHHHHCCCCCCCCEEEHHHCEEEECCHHHHHHHHHCCCCCCCCCCCHH
ESLNPLRMTNEEPVDTTQYIEVQHDGSVIEKRETIFDEDEYIINIGPQHPATHGVLRFRV
HCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEE
SLEGEIIKKLDVHCGYIHRGIEKMCESLTYPQTLALTDRLDYLGAHQNRHALCMCIEQAM
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GVEVSERVQYIRTIMDELQRIDSHLLFFSCLCMDMGALTAFFYGFRDREKILDIFEATTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
GRLIQNYNTIGGVQADIAPDFVQKVKEFIAYLRPMLKEYHEVFTGNVIAQERLKGVGVLS
CHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
REDAISFGATGGTGRASGWACDVRKRHPYAMYGKVDFKEIVHTEGDCFARYMVRMEEILE
CCCCCEECCCCCCCCCCCEEEECCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHH
SMDIIEQLIDNIPEGNYQEKMKPIIRVPEGNYYAAVEGSRGEFGVYLESRGDKFPYRMKF
HHHHHHHHHHHCCCCCHHHHCCCEEECCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEE
RATGLPLVSAMETMCRNAKIADLIAIGGTVDYVVPDIDR
EECCCHHHHHHHHHHCCCCHHHHEEECCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA