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The map label for this gene is nuoH

Identifier: 150004310

GI number: 150004310

Start: 2252836

End: 2253912

Strand: Reverse

Name: nuoH

Synonym: BVU_1756

Alternate gene names: 150004310

Gene position: 2253912-2252836 (Counterclockwise)

Preceding gene: 150004311

Following gene: 150004309

Centisome position: 43.65

GC content: 42.43

Gene sequence:

>1077_bases
ATGTTCGATTTTAGTATAGTCACCCAATGGGTACACTCACTGCTCACGTCATTTATGCCTGAAGAACTGGCAGTGCTCAT
AGAATGTATAGTAATTGGCGTATGTATCATGTTGGCATATGCAGTTATTGCTATCATTATGATTTTCATGGAACGTAAAG
TGTGCGCCGCTTTCCAATGCCGCTTGGGGCCAATGCGTGTAGGTCCCCAAGGTACCATACAGGTGTTTGCCGATGTATTC
AAGATGTTGATCAAGGAAATTATCACCATCCGGCATGCTGACAAGTTCCTGTACAATTTGGCACCTTACATTGTTATCCT
CGCCTCTATCATGGCTTTCAGTTGCCTACCCATCAACAAGGGCATGGAGGTCCTTGATTTCAATGTAGGTATTTTCTTCT
TATTGGCAGCATCCAGTATCGGCGTGGTAGGTATTTTGCTGGCAGGTTGGAGTTCCAATAACAAATATTCATTAATCGGA
GCCATGCGAAGTGGCGCTCAAATGATTAGTTATGAATTATCTGTAGGATTAAGCATCCTTACCATTGTAATCTTAACAGA
TACCATGCAACTAAGCGAAATTGTAGAACGCCAAGCTGACGGCTGGTTCCTTTTTAAAGGACATATACCTGCATTGATCG
CTTTTATCATTTATCTGATAGCCGGAAATGCAGAAGTCAACCGCGGCCCGTTTGACTTGCCTGAAGCAGAAAGTGAACTG
ACTGCGGGATATCATACCGAATATTCCGGTATGCACTTCGGTCTGTTCTATGTGGCAGAATTTGTAAACTTGTTTATCAT
CGCCGCAGTAGCCACAACCATCTTCCTGGGAGGATGGATGCCGCTACATATTCCTGGGCTAGACGGATTCAATGCCATCA
TGGATTATATACCCGGATTTATTTGGTTCTTTGGCAAGTCATTCTTTGTAGTATGGTTACTAATGTGGATCAAATGGACA
TTTCCCCGTCTGCGTATTGACCAAATTCTAACGCTGGAATGGAAGTACTTGGTTCCAATAGGTTTGTGCAACCTGTTGTT
GATGGTAATTATTGTTGTATTTAAATTACATTTCTGA

Upstream 100 bases:

>100_bases
CAATTTGGAGAATGCACTATTTATCAGACTGAGAATTAACAAATTAAATAATTACAAGTTTGCCTATTGGCAAATTAGCA
AATTGACACATTATTAAATT

Downstream 100 bases:

>100_bases
TGAAAGAAGAAAAACATTCCTATATAAAAGGGCTGCTTCATGGCATCGGTACATTACTTACCGGCATGAAAGTGACAGGA
CGAGAGTTCTTCACTCCTAA

Product: NADH dehydrogenase I chain H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MFDFSIVTQWVHSLLTSFMPEELAVLIECIVIGVCIMLAYAVIAIIMIFMERKVCAAFQCRLGPMRVGPQGTIQVFADVF
KMLIKEIITIRHADKFLYNLAPYIVILASIMAFSCLPINKGMEVLDFNVGIFFLLAASSIGVVGILLAGWSSNNKYSLIG
AMRSGAQMISYELSVGLSILTIVILTDTMQLSEIVERQADGWFLFKGHIPALIAFIIYLIAGNAEVNRGPFDLPEAESEL
TAGYHTEYSGMHFGLFYVAEFVNLFIIAAVATTIFLGGWMPLHIPGLDGFNAIMDYIPGFIWFFGKSFFVVWLLMWIKWT
FPRLRIDQILTLEWKYLVPIGLCNLLLMVIIVVFKLHF

Sequences:

>Translated_358_residues
MFDFSIVTQWVHSLLTSFMPEELAVLIECIVIGVCIMLAYAVIAIIMIFMERKVCAAFQCRLGPMRVGPQGTIQVFADVF
KMLIKEIITIRHADKFLYNLAPYIVILASIMAFSCLPINKGMEVLDFNVGIFFLLAASSIGVVGILLAGWSSNNKYSLIG
AMRSGAQMISYELSVGLSILTIVILTDTMQLSEIVERQADGWFLFKGHIPALIAFIIYLIAGNAEVNRGPFDLPEAESEL
TAGYHTEYSGMHFGLFYVAEFVNLFIIAAVATTIFLGGWMPLHIPGLDGFNAIMDYIPGFIWFFGKSFFVVWLLMWIKWT
FPRLRIDQILTLEWKYLVPIGLCNLLLMVIIVVFKLHF
>Mature_358_residues
MFDFSIVTQWVHSLLTSFMPEELAVLIECIVIGVCIMLAYAVIAIIMIFMERKVCAAFQCRLGPMRVGPQGTIQVFADVF
KMLIKEIITIRHADKFLYNLAPYIVILASIMAFSCLPINKGMEVLDFNVGIFFLLAASSIGVVGILLAGWSSNNKYSLIG
AMRSGAQMISYELSVGLSILTIVILTDTMQLSEIVERQADGWFLFKGHIPALIAFIIYLIAGNAEVNRGPFDLPEAESEL
TAGYHTEYSGMHFGLFYVAEFVNLFIIAAVATTIFLGGWMPLHIPGLDGFNAIMDYIPGFIWFFGKSFFVVWLLMWIKWT
FPRLRIDQILTLEWKYLVPIGLCNLLLMVIIVVFKLHF

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family

Homologues:

Organism=Homo sapiens, GI251831107, Length=300, Percent_Identity=35.3333333333333, Blast_Score=185, Evalue=7e-47,
Organism=Escherichia coli, GI1788618, Length=340, Percent_Identity=39.7058823529412, Blast_Score=252, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOH_BACV8 (A6L168)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001299054.1
- STRING:   A6L168
- GeneID:   5302722
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1756
- NMPDR:   fig|435590.6.peg.1653
- eggNOG:   COG1005
- HOGENOM:   HBG727670
- OMA:   NMCWKIM
- ProtClustDB:   CLSK823771
- HAMAP:   MF_01350
- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086
- PANTHER:   PTHR11432

Pfam domain/function: PF00146 NADHdh

EC number: =1.6.99.5

Molecular weight: Translated: 40264; Mature: 40264

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00667 COMPLEX1_ND1_1; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c9f926c)-; HASH(0x1bc5af00)-; HASH(0x1c8654a4)-; HASH(0x1c845868)-; HASH(0x1c0f97e4)-; HASH(0x1c49f088)-; HASH(0x1bd5d0dc)-; HASH(0x1a9ed858)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDFSIVTQWVHSLLTSFMPEELAVLIECIVIGVCIMLAYAVIAIIMIFMERKVCAAFQC
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLGPMRVGPQGTIQVFADVFKMLIKEIITIRHADKFLYNLAPYIVILASIMAFSCLPINK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GMEVLDFNVGIFFLLAASSIGVVGILLAGWSSNNKYSLIGAMRSGAQMISYELSVGLSIL
CCEEEEECHHHHHHHHHHHHHHHHHHEECCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHH
TIVILTDTMQLSEIVERQADGWFLFKGHIPALIAFIIYLIAGNAEVNRGPFDLPEAESEL
HHHHHHCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
TAGYHTEYSGMHFGLFYVAEFVNLFIIAAVATTIFLGGWMPLHIPGLDGFNAIMDYIPGF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
IWFFGKSFFVVWLLMWIKWTFPRLRIDQILTLEWKYLVPIGLCNLLLMVIIVVFKLHF
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MFDFSIVTQWVHSLLTSFMPEELAVLIECIVIGVCIMLAYAVIAIIMIFMERKVCAAFQC
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLGPMRVGPQGTIQVFADVFKMLIKEIITIRHADKFLYNLAPYIVILASIMAFSCLPINK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GMEVLDFNVGIFFLLAASSIGVVGILLAGWSSNNKYSLIGAMRSGAQMISYELSVGLSIL
CCEEEEECHHHHHHHHHHHHHHHHHHEECCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHH
TIVILTDTMQLSEIVERQADGWFLFKGHIPALIAFIIYLIAGNAEVNRGPFDLPEAESEL
HHHHHHCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
TAGYHTEYSGMHFGLFYVAEFVNLFIIAAVATTIFLGGWMPLHIPGLDGFNAIMDYIPGF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
IWFFGKSFFVVWLLMWIKWTFPRLRIDQILTLEWKYLVPIGLCNLLLMVIIVVFKLHF
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA