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The map label for this gene is dmsA [H]

Identifier: 148828212

GI number: 148828212

Start: 1640490

End: 1640639

Strand: Reverse

Name: dmsA [H]

Synonym: CGSHiGG_08870

Alternate gene names: 148828212

Gene position: 1640639-1640490 (Counterclockwise)

Preceding gene: 148828213

Following gene: 148828211

Centisome position: 86.94

GC content: 44.67

Gene sequence:

>150_bases
GTGGCATTAAGCGAGGGGGCTTGGTATGCACCAGATAAAGATCGTATCGATCATTCAGGTTGCATTAATGTACTTACGAC
ACAACGCCCATCACCGCTTGCGAAAGGTAATCCGCAACATTCTAATTTAGTTCAAGTGGAACGTTTGTAG

Upstream 100 bases:

>100_bases
AACCTCGTAATATTAAAAATGGCGATATGATTCGTATCTTTAATGATCGAGGCGAAGTACGTATTAATGTAAAAATTACC
CCCGTATTATTCCAGGGGTT

Downstream 100 bases:

>100_bases
GGGGATAATTATGGAACAATATGGTTTTTATTTTGATTCTGAACGCTGCACAGGCTGTAAAACTTGTGAATTAGCCTGTA
AGGATTACAAAGATCTTGGC

Product: anaerobic dimethyl sulfoxide reductase chain A

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase [H]

Number of amino acids: Translated: 49; Mature: 48

Protein sequence:

>49_residues
MALSEGAWYAPDKDRIDHSGCINVLTTQRPSPLAKGNPQHSNLVQVERL

Sequences:

>Translated_49_residues
MALSEGAWYAPDKDRIDHSGCINVLTTQRPSPLAKGNPQHSNLVQVERL
>Mature_48_residues
ALSEGAWYAPDKDRIDHSGCINVLTTQRPSPLAKGNPQHSNLVQVERL

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081797, Length=49, Percent_Identity=75.5102040816327, Blast_Score=86, Evalue=6e-19,
Organism=Escherichia coli, GI1787870, Length=50, Percent_Identity=60, Blast_Score=72, Evalue=7e-15,
Organism=Escherichia coli, GI171474008, Length=50, Percent_Identity=62, Blast_Score=70, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011888
- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 5415; Mature: 5284

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSEGAWYAPDKDRIDHSGCINVLTTQRPSPLAKGNPQHSNLVQVERL
CCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
ALSEGAWYAPDKDRIDHSGCINVLTTQRPSPLAKGNPQHSNLVQVERL
CCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: Fe; Mo [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8635740 [H]