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The map label for this gene is ulaD

Identifier: 148828191

GI number: 148828191

Start: 1618474

End: 1619151

Strand: Reverse

Name: ulaD

Synonym: CGSHiGG_08735

Alternate gene names: 148828191

Gene position: 1619151-1618474 (Counterclockwise)

Preceding gene: 148828192

Following gene: 148828190

Centisome position: 85.8

GC content: 34.96

Gene sequence:

>678_bases
ATGGGAAAACCTTTATTACAAATCGCTCTTGATGCCCAATATTTAGAGACTGCATTAGTTGATGTAAAACAGATTGAACA
TAATATAGATATTATTGAAGTCGGAACAATTCTTGCATGTTCAGAGGGAATGCGTGCAGTGCGAATATTACGTGCGTTAT
ATCCTAATCAAATTCTTGTTTGCGATCTTAAAACAACAGATGCAGGTGCTACTTTAGCAAAAATGGCATTTGAAGCTGGG
GCAGATTGGCTTACCGTATCAGCAGCAGCTCATCCAGCAACAAAAGCAGCTTGCCAAAAAGTAGCAGAAGAATTTAACAA
AATTCAACCTAATCTTGGTGTACCAAAGGAAATTCAAATTGAACTTTATGGTAATTGGAATTTTGATGAAGTAAAAAACT
GGCTTCAACTTGGTATCAAACAAGCCATCTATCACCGTTCAAGAGATGCCGAATTATCTGGTTTAAGTTGGTCAAATCAA
GATATTGAAAATATAGAAAAATTAGATTCATTAGGTATCGAATTATCTATTACAGGAGGTATTACTCCTGACGATCTCCA
TTTGTTTAAAAATACAAAAAATTTGAAAGCGTTTATTGCGGGTAGAGCATTAGTTGGTAAATCAGGTCGAGAGATAGCAG
AGCAATTAAAACAGAAAATAGGGCAATTTTGGATATAA

Upstream 100 bases:

>100_bases
GATAAACATTATCTACGCAAACATGGTCAAAATGCCTATTATGGTCAATAAATTAAAGACAGAATTATACTGCCTTCCTC
ATATTATTTAAGGAAAAACG

Downstream 100 bases:

>100_bases
AGGCAGAATAGTATAAAATAGCTGCCACCTAATTTTCACATAGTAACCTTGCAAGATATTGTTACAAGTATTTGCACTCA
CTTTCGGTCAAGATTAGGAA

Product: 3-keto-L-gulonate-6-phosphate decarboxylase

Products: NA

Alternate protein names: KGPDC; 3-dehydro-L-gulonate-6-phosphate decarboxylase

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MGKPLLQIALDAQYLETALVDVKQIEHNIDIIEVGTILACSEGMRAVRILRALYPNQILVCDLKTTDAGATLAKMAFEAG
ADWLTVSAAAHPATKAACQKVAEEFNKIQPNLGVPKEIQIELYGNWNFDEVKNWLQLGIKQAIYHRSRDAELSGLSWSNQ
DIENIEKLDSLGIELSITGGITPDDLHLFKNTKNLKAFIAGRALVGKSGREIAEQLKQKIGQFWI

Sequences:

>Translated_225_residues
MGKPLLQIALDAQYLETALVDVKQIEHNIDIIEVGTILACSEGMRAVRILRALYPNQILVCDLKTTDAGATLAKMAFEAG
ADWLTVSAAAHPATKAACQKVAEEFNKIQPNLGVPKEIQIELYGNWNFDEVKNWLQLGIKQAIYHRSRDAELSGLSWSNQ
DIENIEKLDSLGIELSITGGITPDDLHLFKNTKNLKAFIAGRALVGKSGREIAEQLKQKIGQFWI
>Mature_224_residues
GKPLLQIALDAQYLETALVDVKQIEHNIDIIEVGTILACSEGMRAVRILRALYPNQILVCDLKTTDAGATLAKMAFEAGA
DWLTVSAAAHPATKAACQKVAEEFNKIQPNLGVPKEIQIELYGNWNFDEVKNWLQLGIKQAIYHRSRDAELSGLSWSNQD
IENIEKLDSLGIELSITGGITPDDLHLFKNTKNLKAFIAGRALVGKSGREIAEQLKQKIGQFWI

Specific function: Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. KGPDC subfamily

Homologues:

Organism=Escherichia coli, GI1790006, Length=225, Percent_Identity=46.2222222222222, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI1790640, Length=225, Percent_Identity=43.1111111111111, Blast_Score=188, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SGBH_HAEIN (P44988)

Other databases:

- EMBL:   L42023
- PIR:   F64164
- RefSeq:   NP_439184.1
- ProteinModelPortal:   P44988
- SMR:   P44988
- GeneID:   950714
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1024
- NMPDR:   fig|71421.1.peg.986
- TIGR:   HI_1024
- HOGENOM:   HBG417610
- OMA:   ILCISAG
- ProtClustDB:   PRK13306
- BioCyc:   HINF71421:HI_1024-MONOMER
- BRENDA:   4.1.1.85
- InterPro:   IPR013785
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.85

Molecular weight: Translated: 24867; Mature: 24736

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: BINDING 11-11 BINDING 202-202

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKPLLQIALDAQYLETALVDVKQIEHNIDIIEVGTILACSEGMRAVRILRALYPNQILV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEE
CDLKTTDAGATLAKMAFEAGADWLTVSAAAHPATKAACQKVAEEFNKIQPNLGVPKEIQI
EEECCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
ELYGNWNFDEVKNWLQLGIKQAIYHRSRDAELSGLSWSNQDIENIEKLDSLGIELSITGG
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECC
ITPDDLHLFKNTKNLKAFIAGRALVGKSGREIAEQLKQKIGQFWI
CCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKPLLQIALDAQYLETALVDVKQIEHNIDIIEVGTILACSEGMRAVRILRALYPNQILV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEE
CDLKTTDAGATLAKMAFEAGADWLTVSAAAHPATKAACQKVAEEFNKIQPNLGVPKEIQI
EEECCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
ELYGNWNFDEVKNWLQLGIKQAIYHRSRDAELSGLSWSNQDIENIEKLDSLGIELSITGG
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECC
ITPDDLHLFKNTKNLKAFIAGRALVGKSGREIAEQLKQKIGQFWI
CCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 9274005