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The map label for this gene is ispH [H]

Identifier: 148828175

GI number: 148828175

Start: 1600779

End: 1601723

Strand: Direct

Name: ispH [H]

Synonym: CGSHiGG_08635

Alternate gene names: 148828175

Gene position: 1600779-1601723 (Clockwise)

Preceding gene: 148828174

Following gene: 148828176

Centisome position: 84.82

GC content: 40.32

Gene sequence:

>945_bases
ATGAAGATAATTTTAGCCAATCCACGAGGATTCTGTGCCGGTGTAGACCGTGCTATTAGTATTGTTGAACTCGCCTTAGA
AATTCATGGCGCACCGATTTATGTTCGTCATGAAGTGGTGCATAACCGATTTGTTGTGAACGGATTGCGTGATCGTGGTG
CGATCTTCGTGGAAGAATTAAGCGAGGTACCTGATGGTGCGATCGTGATTTTTTCTGCGCACGGTGTATCTCAAGCCGTT
CGACAAGAAGCGAAAGACCGCAATCTCAAAGTATTTGATGCAACCTGTCCTTTGGTGACCAAAGTGCATATGCAAGTTGC
TCGTGCAAGTCGAAAGGGAACAAAAGCGATTTTGATTGGACATAAAGGACACCCTGAAGTTGAAGGCACAATGGGGCAGT
ATAGTAATGAAGATGGCGGAATTTTCTTGATTGAAAAAGTAGAAGATATTGCACGTTTGCCAATGCAAGACAATGATGAT
TTAACCTTTATGACGCAAACCACTTTATCGCTAGATGATACAGCAGAAACTATTGCTGCATTAAAAGAAAAATATCCCGC
TATTCAAGGGCCACATAAAAACGATATTTGTTATGCGACAACCAATCGTCAAGAAGCGGTGCGAGAATTGGCTAAATTAT
CAGATTTAGTGTTGGTTGTGGGGTCTAAAAACTCATCAAATTCAAATCGTTTAGCTGAATTGGCGTCTCGAATGGGGATT
AAATCACAGCTTCTTGATGATCCTTCCGATATTCAAGATGATTGGTTTAATGATGTAAAAACCATTGGGATTACAGCTGG
TGCTTCTGCACCAGAAGAATTAGTTCAATCGATTATTTCCCGCTTAAAAGAGTTTGGTGCGAATACTATAGAAGAACTGC
AAGGTTTAGAAGAAAATATGTTCTTTGAGGTGCCAAAAGAGCTGAGAATAAAAGAAGTTAATTAA

Upstream 100 bases:

>100_bases
ATATTGCCATTTGTATTGGCGCAGGGTTGTTAGCATTGGATGCGTTTAAGAGCGAAAAGAAAAAAGTACAAGATAAACAA
GTAGAAAAGTGCGGTCAGAA

Downstream 100 bases:

>100_bases
TATTAAGGGCTTGTCGTAAATGATAAGCCCTTTGTTTTTTCATTCAAATTAAGAATTTTTGCGATCGAGATCGCAAAAGT
GCGGTCAGTTTCTTGAGGGT

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKIILANPRGFCAGVDRAISIVELALEIHGAPIYVRHEVVHNRFVVNGLRDRGAIFVEELSEVPDGAIVIFSAHGVSQAV
RQEAKDRNLKVFDATCPLVTKVHMQVARASRKGTKAILIGHKGHPEVEGTMGQYSNEDGGIFLIEKVEDIARLPMQDNDD
LTFMTQTTLSLDDTAETIAALKEKYPAIQGPHKNDICYATTNRQEAVRELAKLSDLVLVVGSKNSSNSNRLAELASRMGI
KSQLLDDPSDIQDDWFNDVKTIGITAGASAPEELVQSIISRLKEFGANTIEELQGLEENMFFEVPKELRIKEVN

Sequences:

>Translated_314_residues
MKIILANPRGFCAGVDRAISIVELALEIHGAPIYVRHEVVHNRFVVNGLRDRGAIFVEELSEVPDGAIVIFSAHGVSQAV
RQEAKDRNLKVFDATCPLVTKVHMQVARASRKGTKAILIGHKGHPEVEGTMGQYSNEDGGIFLIEKVEDIARLPMQDNDD
LTFMTQTTLSLDDTAETIAALKEKYPAIQGPHKNDICYATTNRQEAVRELAKLSDLVLVVGSKNSSNSNRLAELASRMGI
KSQLLDDPSDIQDDWFNDVKTIGITAGASAPEELVQSIISRLKEFGANTIEELQGLEENMFFEVPKELRIKEVN
>Mature_314_residues
MKIILANPRGFCAGVDRAISIVELALEIHGAPIYVRHEVVHNRFVVNGLRDRGAIFVEELSEVPDGAIVIFSAHGVSQAV
RQEAKDRNLKVFDATCPLVTKVHMQVARASRKGTKAILIGHKGHPEVEGTMGQYSNEDGGIFLIEKVEDIARLPMQDNDD
LTFMTQTTLSLDDTAETIAALKEKYPAIQGPHKNDICYATTNRQEAVRELAKLSDLVLVVGSKNSSNSNRLAELASRMGI
KSQLLDDPSDIQDDWFNDVKTIGITAGASAPEELVQSIISRLKEFGANTIEELQGLEENMFFEVPKELRIKEVN

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=316, Percent_Identity=68.3544303797468, Blast_Score=461, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 34603; Mature: 34603

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIILANPRGFCAGVDRAISIVELALEIHGAPIYVRHEVVHNRFVVNGLRDRGAIFVEEL
CEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHH
SEVPDGAIVIFSAHGVSQAVRQEAKDRNLKVFDATCPLVTKVHMQVARASRKGTKAILIG
HHCCCCEEEEEECCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEE
HKGHPEVEGTMGQYSNEDGGIFLIEKVEDIARLPMQDNDDLTFMTQTTLSLDDTAETIAA
CCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHHHH
LKEKYPAIQGPHKNDICYATTNRQEAVRELAKLSDLVLVVGSKNSSNSNRLAELASRMGI
HHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCC
KSQLLDDPSDIQDDWFNDVKTIGITAGASAPEELVQSIISRLKEFGANTIEELQGLEENM
HHHHCCCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHH
FFEVPKELRIKEVN
HECCCHHCCEEECC
>Mature Secondary Structure
MKIILANPRGFCAGVDRAISIVELALEIHGAPIYVRHEVVHNRFVVNGLRDRGAIFVEEL
CEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHH
SEVPDGAIVIFSAHGVSQAVRQEAKDRNLKVFDATCPLVTKVHMQVARASRKGTKAILIG
HHCCCCEEEEEECCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEE
HKGHPEVEGTMGQYSNEDGGIFLIEKVEDIARLPMQDNDDLTFMTQTTLSLDDTAETIAA
CCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHHHH
LKEKYPAIQGPHKNDICYATTNRQEAVRELAKLSDLVLVVGSKNSSNSNRLAELASRMGI
HHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCC
KSQLLDDPSDIQDDWFNDVKTIGITAGASAPEELVQSIISRLKEFGANTIEELQGLEENM
HHHHCCCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHH
FFEVPKELRIKEVN
HECCCHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA