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The map label for this gene is lspA [H]

Identifier: 148828174

GI number: 148828174

Start: 1600267

End: 1600782

Strand: Direct

Name: lspA [H]

Synonym: CGSHiGG_08630

Alternate gene names: 148828174

Gene position: 1600267-1600782 (Clockwise)

Preceding gene: 148828173

Following gene: 148828175

Centisome position: 84.8

GC content: 35.85

Gene sequence:

>516_bases
ATGTCCAAAAAATCAGGGCTTTCGTTTTTATGGTTAAGTGCGGTCGCTTTTGTGGTTGATTTGCTTACAAAATACATTGT
GGTACAAAAATTTGATTTGTATGAAAGTGTTAATGTGCTGCCTGTTTTTAACCTGACTTATGTTCGCAATTATGGCGCAG
CATTTAGTTTCTTGGCAGATCATAGTGGCTGGCAACAATATTTCTTTATTTTGTTGGCATTGGCTATTTCAGGCATGTTG
GTTTATTTTTTAGCAAAAAATAATGCCGAACAAAAAATCCAAAATTCTGCTTATGCACTGATTATTGGTGGTGCATTAGC
GAATATGGTAGATCGAGCTTATAACGGTTTTGTCGTGGATTTCTTTGATTTCTATTGGGATATTTACCATTATCCAGTGT
TTAATATCGCCGATATTGCCATTTGTATTGGCGCAGGGTTGTTAGCATTGGATGCGTTTAAGAGCGAAAAGAAAAAAGTA
CAAGATAAACAAGTAGAAAAGTGCGGTCAGAAATGA

Upstream 100 bases:

>100_bases
TCCAGCAAAATTACCAGAAGCCGTTCAGTAAATAAGATCCTGCTTTATCATTTATCGGCTTGTGCTAGAATGAGCGGAAT
TTTTTTAAAAGGGAAATAGT

Downstream 100 bases:

>100_bases
AGATAATTTTAGCCAATCCACGAGGATTCTGTGCCGGTGTAGACCGTGCTATTAGTATTGTTGAACTCGCCTTAGAAATT
CATGGCGCACCGATTTATGT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MSKKSGLSFLWLSAVAFVVDLLTKYIVVQKFDLYESVNVLPVFNLTYVRNYGAAFSFLADHSGWQQYFFILLALAISGML
VYFLAKNNAEQKIQNSAYALIIGGALANMVDRAYNGFVVDFFDFYWDIYHYPVFNIADIAICIGAGLLALDAFKSEKKKV
QDKQVEKCGQK

Sequences:

>Translated_171_residues
MSKKSGLSFLWLSAVAFVVDLLTKYIVVQKFDLYESVNVLPVFNLTYVRNYGAAFSFLADHSGWQQYFFILLALAISGML
VYFLAKNNAEQKIQNSAYALIIGGALANMVDRAYNGFVVDFFDFYWDIYHYPVFNIADIAICIGAGLLALDAFKSEKKKV
QDKQVEKCGQK
>Mature_170_residues
SKKSGLSFLWLSAVAFVVDLLTKYIVVQKFDLYESVNVLPVFNLTYVRNYGAAFSFLADHSGWQQYFFILLALAISGMLV
YFLAKNNAEQKIQNSAYALIIGGALANMVDRAYNGFVVDFFDFYWDIYHYPVFNIADIAICIGAGLLALDAFKSEKKKVQ
DKQVEKCGQK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=158, Percent_Identity=50, Blast_Score=167, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19321; Mature: 19189

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKSGLSFLWLSAVAFVVDLLTKYIVVQKFDLYESVNVLPVFNLTYVRNYGAAFSFLAD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHC
HSGWQQYFFILLALAISGMLVYFLAKNNAEQKIQNSAYALIIGGALANMVDRAYNGFVVD
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCHH
FFDFYWDIYHYPVFNIADIAICIGAGLLALDAFKSEKKKVQDKQVEKCGQK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKKSGLSFLWLSAVAFVVDLLTKYIVVQKFDLYESVNVLPVFNLTYVRNYGAAFSFLAD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHC
HSGWQQYFFILLALAISGMLVYFLAKNNAEQKIQNSAYALIIGGALANMVDRAYNGFVVD
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCHH
FFDFYWDIYHYPVFNIADIAICIGAGLLALDAFKSEKKKVQDKQVEKCGQK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA