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The map label for this gene is ppiD [H]

Identifier: 148828172

GI number: 148828172

Start: 1596682

End: 1598550

Strand: Direct

Name: ppiD [H]

Synonym: CGSHiGG_08620

Alternate gene names: 148828172

Gene position: 1596682-1598550 (Clockwise)

Preceding gene: 148828171

Following gene: 148828173

Centisome position: 84.61

GC content: 34.94

Gene sequence:

>1869_bases
ATGTTAATTGAAAAAATGCACAATTTAACAAACTCAAAGATTTCTAAATTTATCTTAGGTTTGATTGCTGTATCGTTTTT
AGTTGGTGGAATGTCTGGCTATCTTTTTAGCTCAAATGATACCTATGCGGCAAAAGTGAACGGCGAAGTGATTTCTCAAC
AAGATTTTTTAAATCGCTATAATCAAGAGTTTGAAATACGCGCACAACGTGAGGGAGAGGCGTTTGTGGCTCAGTCTGAT
TCTCCTGAATTTGTTACCGCACTTCGTCAAAACATCGTCAATCTAATGATTGATCAAGAATTACTTCGCCAATATGTTAA
AGAATTAAAATTAGGCGTGAGTGATGAAATGATTAAACGTGCAATCGTGACCGATCCTAATTTTCAAGTAAAGGGTAAAT
TTGATAATGCTGTTTATCAACGAATATTACAACAAAATCATTTAACTTCAGATGGTTACGCTTCAATTTTGCGTGCTTCG
TTACCTCTTGAACAAATACAAAATGGCGTTGCTAACAGTGAATTTATTGTTCCTGCTCAAGTAAAAAATAGCGCAGAAAT
TTTCTTTCAAAAGCGTTTAGCTCGTTTAGCAACTTTATCTCTTGCAGATGAAATGGCAAAACAATCAGTCTCTGATGATG
AAATCAAAACGTATTATGAAGCTAATCAAAAGTCTTTTGTTCAGCCAGAGCAGGTTAAAGTTCAGTATATTGATCTTTCT
GCAGATAACATCAGTAGAAATCTTCAAGTTACAGATGTAGAAATTGCGCAATATTATCAAGATAATAAAGCACAATTTAT
GACTCAACATTTAGCACATATTCAATTTGCAAATGAACAAGATGCGAAAGTGGCTTACGAGGAATTACAGAAAGGGGCAA
ATTTCGCTGATGTCGCTAAAGCGAAATCTTTGGATAAAATTTCTGGTGAGAATGGCGGGGATTTAGGCTGGGTAAATGAG
AATGAATTACCAAAAGCCTTTGAAGATGCCGCAGCTGCATTGCAGGTAGGGCAATATAGCCAACCAATCAATGTGGATGG
CAATTACCATATTGTGTTAGTGCAAGAACGTAAAGCGCAAAGTTTGGAGAATGTGAAAGCTCAAATTGCAGATTTAGTTC
GTAAATCTTTGATGGAGAGTCGTTATTTTTCTTTAGAAAAACAAGCGAGTGATAAGGCTTTTGAAGACAGTAAGTCACTT
AATACTGCAGCACAAGCAGCAGGTGTTAAGGTTCAAGAGAGCGATTATTTTTCTCGTCAAAATGTGCCAGCTGGATTAAA
TTTCCCTAATGTTATTTACACAATATTTGAATCAGATACTACGAATGTTGGTATGAATTCTGAACCAATTAATGTAGGCG
ATTATCACACAATTATTGTACGTGTGTTGGATCGCAAAGCAGAGGGCGTAAAAAGTTTAGAAGAGGCTAAAATAGATATT
GAAACTTTCTTAAAACGTCAGAAAGCTGAGAATGTGCTTAATGAAAAAGCACAACAAGCAGTGAAAAAATTAAGTGAAAA
CCCTGAATCAAAAATAGATGGCATTAATTTCTCAAGTGAGCAGACTTTTACGTTAAGTGAAAATAAAGATCCTATTTTAA
CAAATGGTATATTTTCAATTGCTAAACCAAAATCAAATGAAGCTCTTTATCAAGTGGTGCATAATTCAAATGGCGATGTG
GTTGTTGTTGCCTTGAATAAGGTTGAACAAAGCAGTTTAAGTGAAAAAGAATTGTCGCAATTTGGTATGCAATTATTGCG
TAGTCATCAATCTGAATTACAAGTTCAGTTAATACAAGGATTACGTGAGAGAGCGAAAATTGAGGTAAATGACTCTTTCA
TCAATCAAGATGATGAAGTGCAACAATAA

Upstream 100 bases:

>100_bases
GCTGGCTTTGTGAGGATGGCGTTTTCACTTTTTAAGATGCTAATTTTTTACGTTTAGATTATAATCGGGAAAATTTTATA
TTTATAACAAGGGTTATAGA

Downstream 100 bases:

>100_bases
CAGGTTAAATGATAATTTGAGATAAATTTTGCTCAAAAGTGCGGTAAATTTCACCGCACTTTTTTACTTTTGTGCAAAAG
GAAGTTAATGATGTTCGGGA

Product: peptidyl-prolyl cis-trans isomerase D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MLIEKMHNLTNSKISKFILGLIAVSFLVGGMSGYLFSSNDTYAAKVNGEVISQQDFLNRYNQEFEIRAQREGEAFVAQSD
SPEFVTALRQNIVNLMIDQELLRQYVKELKLGVSDEMIKRAIVTDPNFQVKGKFDNAVYQRILQQNHLTSDGYASILRAS
LPLEQIQNGVANSEFIVPAQVKNSAEIFFQKRLARLATLSLADEMAKQSVSDDEIKTYYEANQKSFVQPEQVKVQYIDLS
ADNISRNLQVTDVEIAQYYQDNKAQFMTQHLAHIQFANEQDAKVAYEELQKGANFADVAKAKSLDKISGENGGDLGWVNE
NELPKAFEDAAAALQVGQYSQPINVDGNYHIVLVQERKAQSLENVKAQIADLVRKSLMESRYFSLEKQASDKAFEDSKSL
NTAAQAAGVKVQESDYFSRQNVPAGLNFPNVIYTIFESDTTNVGMNSEPINVGDYHTIIVRVLDRKAEGVKSLEEAKIDI
ETFLKRQKAENVLNEKAQQAVKKLSENPESKIDGINFSSEQTFTLSENKDPILTNGIFSIAKPKSNEALYQVVHNSNGDV
VVVALNKVEQSSLSEKELSQFGMQLLRSHQSELQVQLIQGLRERAKIEVNDSFINQDDEVQQ

Sequences:

>Translated_622_residues
MLIEKMHNLTNSKISKFILGLIAVSFLVGGMSGYLFSSNDTYAAKVNGEVISQQDFLNRYNQEFEIRAQREGEAFVAQSD
SPEFVTALRQNIVNLMIDQELLRQYVKELKLGVSDEMIKRAIVTDPNFQVKGKFDNAVYQRILQQNHLTSDGYASILRAS
LPLEQIQNGVANSEFIVPAQVKNSAEIFFQKRLARLATLSLADEMAKQSVSDDEIKTYYEANQKSFVQPEQVKVQYIDLS
ADNISRNLQVTDVEIAQYYQDNKAQFMTQHLAHIQFANEQDAKVAYEELQKGANFADVAKAKSLDKISGENGGDLGWVNE
NELPKAFEDAAAALQVGQYSQPINVDGNYHIVLVQERKAQSLENVKAQIADLVRKSLMESRYFSLEKQASDKAFEDSKSL
NTAAQAAGVKVQESDYFSRQNVPAGLNFPNVIYTIFESDTTNVGMNSEPINVGDYHTIIVRVLDRKAEGVKSLEEAKIDI
ETFLKRQKAENVLNEKAQQAVKKLSENPESKIDGINFSSEQTFTLSENKDPILTNGIFSIAKPKSNEALYQVVHNSNGDV
VVVALNKVEQSSLSEKELSQFGMQLLRSHQSELQVQLIQGLRERAKIEVNDSFINQDDEVQQ
>Mature_622_residues
MLIEKMHNLTNSKISKFILGLIAVSFLVGGMSGYLFSSNDTYAAKVNGEVISQQDFLNRYNQEFEIRAQREGEAFVAQSD
SPEFVTALRQNIVNLMIDQELLRQYVKELKLGVSDEMIKRAIVTDPNFQVKGKFDNAVYQRILQQNHLTSDGYASILRAS
LPLEQIQNGVANSEFIVPAQVKNSAEIFFQKRLARLATLSLADEMAKQSVSDDEIKTYYEANQKSFVQPEQVKVQYIDLS
ADNISRNLQVTDVEIAQYYQDNKAQFMTQHLAHIQFANEQDAKVAYEELQKGANFADVAKAKSLDKISGENGGDLGWVNE
NELPKAFEDAAAALQVGQYSQPINVDGNYHIVLVQERKAQSLENVKAQIADLVRKSLMESRYFSLEKQASDKAFEDSKSL
NTAAQAAGVKVQESDYFSRQNVPAGLNFPNVIYTIFESDTTNVGMNSEPINVGDYHTIIVRVLDRKAEGVKSLEEAKIDI
ETFLKRQKAENVLNEKAQQAVKKLSENPESKIDGINFSSEQTFTLSENKDPILTNGIFSIAKPKSNEALYQVVHNSNGDV
VVVALNKVEQSSLSEKELSQFGMQLLRSHQSELQVQLIQGLRERAKIEVNDSFINQDDEVQQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=628, Percent_Identity=34.2356687898089, Blast_Score=347, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69790; Mature: 69790

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIEKMHNLTNSKISKFILGLIAVSFLVGGMSGYLFSSNDTYAAKVNGEVISQQDFLNRY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCCHHHHHHHC
NQEFEIRAQREGEAFVAQSDSPEFVTALRQNIVNLMIDQELLRQYVKELKLGVSDEMIKR
CCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AIVTDPNFQVKGKFDNAVYQRILQQNHLTSDGYASILRASLPLEQIQNGVANSEFIVPAQ
HHCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCCCEEEEHH
VKNSAEIFFQKRLARLATLSLADEMAKQSVSDDEIKTYYEANQKSFVQPEQVKVQYIDLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEC
ADNISRNLQVTDVEIAQYYQDNKAQFMTQHLAHIQFANEQDAKVAYEELQKGANFADVAK
HHCCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHH
AKSLDKISGENGGDLGWVNENELPKAFEDAAAALQVGQYSQPINVDGNYHIVLVQERKAQ
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECHHHH
SLENVKAQIADLVRKSLMESRYFSLEKQASDKAFEDSKSLNTAAQAAGVKVQESDYFSRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECCCCHHHC
NVPAGLNFPNVIYTIFESDTTNVGMNSEPINVGDYHTIIVRVLDRKAEGVKSLEEAKIDI
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
ETFLKRQKAENVLNEKAQQAVKKLSENPESKIDGINFSSEQTFTLSENKDPILTNGIFSI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEECCCCCCCEECCCHHC
AKPKSNEALYQVVHNSNGDVVVVALNKVEQSSLSEKELSQFGMQLLRSHQSELQVQLIQG
CCCCCCHHHHHHHCCCCCCEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRERAKIEVNDSFINQDDEVQQ
HHHHCEEEECHHHCCCCCCCCC
>Mature Secondary Structure
MLIEKMHNLTNSKISKFILGLIAVSFLVGGMSGYLFSSNDTYAAKVNGEVISQQDFLNRY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCCHHHHHHHC
NQEFEIRAQREGEAFVAQSDSPEFVTALRQNIVNLMIDQELLRQYVKELKLGVSDEMIKR
CCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AIVTDPNFQVKGKFDNAVYQRILQQNHLTSDGYASILRASLPLEQIQNGVANSEFIVPAQ
HHCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCCCEEEEHH
VKNSAEIFFQKRLARLATLSLADEMAKQSVSDDEIKTYYEANQKSFVQPEQVKVQYIDLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEC
ADNISRNLQVTDVEIAQYYQDNKAQFMTQHLAHIQFANEQDAKVAYEELQKGANFADVAK
HHCCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHH
AKSLDKISGENGGDLGWVNENELPKAFEDAAAALQVGQYSQPINVDGNYHIVLVQERKAQ
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECHHHH
SLENVKAQIADLVRKSLMESRYFSLEKQASDKAFEDSKSLNTAAQAAGVKVQESDYFSRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECCCCHHHC
NVPAGLNFPNVIYTIFESDTTNVGMNSEPINVGDYHTIIVRVLDRKAEGVKSLEEAKIDI
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
ETFLKRQKAENVLNEKAQQAVKKLSENPESKIDGINFSSEQTFTLSENKDPILTNGIFSI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEECCCCCCCEECCCHHC
AKPKSNEALYQVVHNSNGDVVVVALNKVEQSSLSEKELSQFGMQLLRSHQSELQVQLIQG
CCCCCCHHHHHHHCCCCCCEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRERAKIEVNDSFINQDDEVQQ
HHHHCEEEECHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]