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The map label for this gene is gcp [H]

Identifier: 148827721

GI number: 148827721

Start: 1076503

End: 1077531

Strand: Reverse

Name: gcp [H]

Synonym: CGSHiGG_05900

Alternate gene names: 148827721

Gene position: 1077531-1076503 (Counterclockwise)

Preceding gene: 148827726

Following gene: 148827720

Centisome position: 57.1

GC content: 42.57

Gene sequence:

>1029_bases
ATGAAAATCTTAGGCATTGAAACTTCCTGTGATGAAACGGGCGTGGCGATTTATGATGAAGAAAAAGGGTTAATTGCTAA
TCAACTTTATACTCAAATTGCCCTGCATGCAGATTATGGTGGTGTGGTTCCTGAATTAGCATCACGCGATCATATTCGGA
AAACAGCGCCTCTTATTAAAGCGGCATTAGAAGAAGCTAAGTTAACGGCGAGCGATATTGATGGTGTTGCTTATACGAGT
GGCCCTGGGCTTGTTGGCGCATTGCTTGTTGGTGCTACGATTGCACGTTCTTTAGCCTATGCTTGGAATGTGCCAGCGAT
TGGTGTTCATCATATGGAAGGGCATTTACTTGCGCCAATGCTTGATGAAAATTCACCGCACTTTCCTTTTGTTGCTCTGT
TGGTATCGGGTGGCCACACTCAATTAGTGCGTGTCGATGGTGTAGGAAAATATGAAGTGATAGGAGAATCTATTGATGAT
GCTGCTGGCGAAGCCTTTGATAAAACAGCAAAATTACTTGGATTAGATTATCCGGGCGGCGCGGCACTTTCTCGTTTAGC
GGAAAAAGGCACGCCAAATCGCTTTATATTTCCACGCCCAATGACAGATCGTGCAGGTCTTGATTTTAGTTTTTCTGGTT
TAAAAACATTTGCCGCGAATACAGTTAATCAAGCGATTAAAAACGAGGGCGAACTGACAGAACAAACTAAAGTAGATATT
GCTTATGCTTTCCAAGATGCGGTGGTAGATACTCTTGCCATTAAATGTAAGCGTGCATTGAAAGAAACAGGTTATAAACG
TTTAGTGATTGCGGGAGGGGTGAGCGCAAATAAAAAACTCCGAGAAACGCTTGCGCACTTAATGCAAAATTTAGGTGGCG
AAGTGTTTTATCCTCAACCTCAATTTTGTACAGATAATGGCGCAATGATTGCTTACACAGGTTTGTTACGTTTAAAACAA
GGTCAGCATAGCGATCTGGCTATTGATGTTAAGCCTCGTTGGGCAATGACGGAATTACTGGCAATTTAG

Upstream 100 bases:

>100_bases
AGAATGCCAATTCACCTTAATATTTGTGGTTTCAACTGGTTAAAACCGCTTAAACAGGGTAAAATCGCGCAGCATTTTAG
GTAATAAATTAAGAAAATCA

Downstream 100 bases:

>100_bases
GAGAAAAAATGGCAAAACTCTACTTCTATTACTCCACAATGAACGCCGGAAAATCAACGACGTTGCTACAATCTTCCTAT
AACTATCGTGAGCGTGATAT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKILGIETSCDETGVAIYDEEKGLIANQLYTQIALHADYGGVVPELASRDHIRKTAPLIKAALEEAKLTASDIDGVAYTS
GPGLVGALLVGATIARSLAYAWNVPAIGVHHMEGHLLAPMLDENSPHFPFVALLVSGGHTQLVRVDGVGKYEVIGESIDD
AAGEAFDKTAKLLGLDYPGGAALSRLAEKGTPNRFIFPRPMTDRAGLDFSFSGLKTFAANTVNQAIKNEGELTEQTKVDI
AYAFQDAVVDTLAIKCKRALKETGYKRLVIAGGVSANKKLRETLAHLMQNLGGEVFYPQPQFCTDNGAMIAYTGLLRLKQ
GQHSDLAIDVKPRWAMTELLAI

Sequences:

>Translated_342_residues
MKILGIETSCDETGVAIYDEEKGLIANQLYTQIALHADYGGVVPELASRDHIRKTAPLIKAALEEAKLTASDIDGVAYTS
GPGLVGALLVGATIARSLAYAWNVPAIGVHHMEGHLLAPMLDENSPHFPFVALLVSGGHTQLVRVDGVGKYEVIGESIDD
AAGEAFDKTAKLLGLDYPGGAALSRLAEKGTPNRFIFPRPMTDRAGLDFSFSGLKTFAANTVNQAIKNEGELTEQTKVDI
AYAFQDAVVDTLAIKCKRALKETGYKRLVIAGGVSANKKLRETLAHLMQNLGGEVFYPQPQFCTDNGAMIAYTGLLRLKQ
GQHSDLAIDVKPRWAMTELLAI
>Mature_342_residues
MKILGIETSCDETGVAIYDEEKGLIANQLYTQIALHADYGGVVPELASRDHIRKTAPLIKAALEEAKLTASDIDGVAYTS
GPGLVGALLVGATIARSLAYAWNVPAIGVHHMEGHLLAPMLDENSPHFPFVALLVSGGHTQLVRVDGVGKYEVIGESIDD
AAGEAFDKTAKLLGLDYPGGAALSRLAEKGTPNRFIFPRPMTDRAGLDFSFSGLKTFAANTVNQAIKNEGELTEQTKVDI
AYAFQDAVVDTLAIKCKRALKETGYKRLVIAGGVSANKKLRETLAHLMQNLGGEVFYPQPQFCTDNGAMIAYTGLLRLKQ
GQHSDLAIDVKPRWAMTELLAI

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=337, Percent_Identity=34.1246290801187, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI8923380, Length=329, Percent_Identity=32.8267477203647, Blast_Score=161, Evalue=8e-40,
Organism=Escherichia coli, GI1789445, Length=341, Percent_Identity=73.0205278592375, Blast_Score=528, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI17557464, Length=333, Percent_Identity=33.033033033033, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI71995670, Length=331, Percent_Identity=32.6283987915408, Blast_Score=146, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320099, Length=376, Percent_Identity=35.3723404255319, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6322891, Length=349, Percent_Identity=30.6590257879656, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI20129063, Length=354, Percent_Identity=34.4632768361582, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21357207, Length=328, Percent_Identity=32.3170731707317, Blast_Score=168, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36707; Mature: 36707

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILGIETSCDETGVAIYDEEKGLIANQLYTQIALHADYGGVVPELASRDHIRKTAPLIK
CEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALEEAKLTASDIDGVAYTSGPGLVGALLVGATIARSLAYAWNVPAIGVHHMEGHLLAPM
HHHHHHHCCHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECCC
LDENSPHFPFVALLVSGGHTQLVRVDGVGKYEVIGESIDDAAGEAFDKTAKLLGLDYPGG
CCCCCCCCCEEEEEEECCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCH
AALSRLAEKGTPNRFIFPRPMTDRAGLDFSFSGLKTFAANTVNQAIKNEGELTEQTKVDI
HHHHHHHHCCCCCCEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHEEE
AYAFQDAVVDTLAIKCKRALKETGYKRLVIAGGVSANKKLRETLAHLMQNLGGEVFYPQP
EEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEECCCC
QFCTDNGAMIAYTGLLRLKQGQHSDLAIDVKPRWAMTELLAI
CCCCCCCCEEEEEEEHHHCCCCCCCEEEEECCCHHHHHHHCC
>Mature Secondary Structure
MKILGIETSCDETGVAIYDEEKGLIANQLYTQIALHADYGGVVPELASRDHIRKTAPLIK
CEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALEEAKLTASDIDGVAYTSGPGLVGALLVGATIARSLAYAWNVPAIGVHHMEGHLLAPM
HHHHHHHCCHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECCC
LDENSPHFPFVALLVSGGHTQLVRVDGVGKYEVIGESIDDAAGEAFDKTAKLLGLDYPGG
CCCCCCCCCEEEEEEECCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCH
AALSRLAEKGTPNRFIFPRPMTDRAGLDFSFSGLKTFAANTVNQAIKNEGELTEQTKVDI
HHHHHHHHCCCCCCEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHEEE
AYAFQDAVVDTLAIKCKRALKETGYKRLVIAGGVSANKKLRETLAHLMQNLGGEVFYPQP
EEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEECCCC
QFCTDNGAMIAYTGLLRLKQGQHSDLAIDVKPRWAMTELLAI
CCCCCCCCEEEEEEEHHHCCCCCCCEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]