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The map label for this gene is yeiJ [C]

Identifier: 148827710

GI number: 148827710

Start: 1065314

End: 1066567

Strand: Reverse

Name: yeiJ [C]

Synonym: CGSHiGG_05845

Alternate gene names: 148827710

Gene position: 1066567-1065314 (Counterclockwise)

Preceding gene: 148827711

Following gene: 148827709

Centisome position: 56.52

GC content: 41.23

Gene sequence:

>1254_bases
ATGAGTGTGTTAAGCAGCATTTTGGGAATGGTCGTATTAATCGCTATTGCCGTGTTACTTTCTAATAATCGTAAAGCGAT
TAGTATTCGAACCGTAGTAGGGGCGTTAGCAATCCAAGTAGGATTTGCCGCCCTTATTTTATATGTGCCAGCAGGTAAAC
AAGCGTTGGGTGCCGCTGCGGATATGGTATCCAATGTTATTGCCTATGGTAATGACGGGATTAATTTCGTTTTCGGCGGA
TTGGCAGATCCAAGTAAACCATCCGGTTTCATTTTTGCAGTGAAAGTATTACCGATTATCGTGTTCTTCTCTGGCTTAAT
TTCTGTGCTTTACTATCTCGGCATTATGCAAGTCGTGATTAAAGTATTAGGTGGCGCATTACAAAAAGCATTGGGTACGT
CAAAAGCGGAATCAATGTCAGCGGCGGCGAATATCTTCGTCGGTCAAACTGAAGCACCATTAGTTGTTCGCCCTTACATT
AAAAATATGACCCAATCTGAATTATTTGCCATTATGGTGGGTGGTACAGCGTCTATCGCGGGTTCAGTAATGGCAGGTTA
TGCTGGAATGGGCGTGCCATTGACATACTTAATCGCTGCGTCATTTATGGCGGCACCAGCAGGTTTATTATTTGCGAAAT
TAATGTTCCCACAAACCGAACAATTCACAGATAAACAACCAGAAGACAATGATTCAGAAAAACCAACTAACGTACTTGAA
GCAATGGCGGGCGGTGCGAGTGCAGGTATGCAACTTGCATTAAACGTAGGTGCAATGTTAATCGCATTCGTTGGTTTAAT
TGCATTAATTAATGGTATTTTAAGTGGCGTAGGCGGATGGTTCGGCTATGGCGACTTAACCTTACAATCTATCTTTGGTT
TAATTTTCAAACCATTAGCATACTTAATCGGTGTAACTGATGGTGCTGAAGCAGGTATCGCAGGACAAATGATCGGTATG
AAATTAGCGGTTAATGAATTTGTGGGTTATCTTGAATTTGCAAAATATTTACAACCAGATTCTGCAATTGTATTAACTGA
AAAAACCAAAGCGATTATTACTTTCGCGCTTTGTGGTTTTGCTAACTTCAGCTCAATTGCAATTTTAATTGGTGGTTTAG
GTGGTATGGCACCAAGTCGTCGTAGTGATGTTGCTCGTTTAGGTATCAAAGCCGTTATCGCTGGTACTCTCGCTAACTTA
ATGAGTGCAACTATTGCTGGTTTATTTATCGGCTTAGGTGCTGCAGCACTTTAA

Upstream 100 bases:

>100_bases
AGACGTTTACAAAAAGTGCGGTGAAAATTCGCCGACTTTTCATAAGAAAACAAGTAGAATAAGCCGAATTTTATTAACTT
AACTAATCTAGGGGAATCAA

Downstream 100 bases:

>100_bases
TTTATCTTAATCAATTAAAAAGTGCGGTAAAAAATGACCGCACTTTATTCATTTTTATTCATTATTAAAAATAAGGAAAA
ATTATGACTCCACATATTAA

Product: nucleoside permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSVLSSILGMVVLIAIAVLLSNNRKAISIRTVVGALAIQVGFAALILYVPAGKQALGAAADMVSNVIAYGNDGINFVFGG
LADPSKPSGFIFAVKVLPIIVFFSGLISVLYYLGIMQVVIKVLGGALQKALGTSKAESMSAAANIFVGQTEAPLVVRPYI
KNMTQSELFAIMVGGTASIAGSVMAGYAGMGVPLTYLIAASFMAAPAGLLFAKLMFPQTEQFTDKQPEDNDSEKPTNVLE
AMAGGASAGMQLALNVGAMLIAFVGLIALINGILSGVGGWFGYGDLTLQSIFGLIFKPLAYLIGVTDGAEAGIAGQMIGM
KLAVNEFVGYLEFAKYLQPDSAIVLTEKTKAIITFALCGFANFSSIAILIGGLGGMAPSRRSDVARLGIKAVIAGTLANL
MSATIAGLFIGLGAAAL

Sequences:

>Translated_417_residues
MSVLSSILGMVVLIAIAVLLSNNRKAISIRTVVGALAIQVGFAALILYVPAGKQALGAAADMVSNVIAYGNDGINFVFGG
LADPSKPSGFIFAVKVLPIIVFFSGLISVLYYLGIMQVVIKVLGGALQKALGTSKAESMSAAANIFVGQTEAPLVVRPYI
KNMTQSELFAIMVGGTASIAGSVMAGYAGMGVPLTYLIAASFMAAPAGLLFAKLMFPQTEQFTDKQPEDNDSEKPTNVLE
AMAGGASAGMQLALNVGAMLIAFVGLIALINGILSGVGGWFGYGDLTLQSIFGLIFKPLAYLIGVTDGAEAGIAGQMIGM
KLAVNEFVGYLEFAKYLQPDSAIVLTEKTKAIITFALCGFANFSSIAILIGGLGGMAPSRRSDVARLGIKAVIAGTLANL
MSATIAGLFIGLGAAAL
>Mature_416_residues
SVLSSILGMVVLIAIAVLLSNNRKAISIRTVVGALAIQVGFAALILYVPAGKQALGAAADMVSNVIAYGNDGINFVFGGL
ADPSKPSGFIFAVKVLPIIVFFSGLISVLYYLGIMQVVIKVLGGALQKALGTSKAESMSAAANIFVGQTEAPLVVRPYIK
NMTQSELFAIMVGGTASIAGSVMAGYAGMGVPLTYLIAASFMAAPAGLLFAKLMFPQTEQFTDKQPEDNDSEKPTNVLEA
MAGGASAGMQLALNVGAMLIAFVGLIALINGILSGVGGWFGYGDLTLQSIFGLIFKPLAYLIGVTDGAEAGIAGQMIGMK
LAVNEFVGYLEFAKYLQPDSAIVLTEKTKAIITFALCGFANFSSIAILIGGLGGMAPSRRSDVARLGIKAVIAGTLANLM
SATIAGLFIGLGAAAL

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family

Homologues:

Organism=Homo sapiens, GI42542381, Length=429, Percent_Identity=37.5291375291375, Blast_Score=275, Evalue=6e-74,
Organism=Homo sapiens, GI11545853, Length=412, Percent_Identity=39.5631067961165, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI227116277, Length=423, Percent_Identity=36.8794326241135, Blast_Score=265, Evalue=4e-71,
Organism=Escherichia coli, GI1788485, Length=421, Percent_Identity=49.4061757719715, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1788488, Length=419, Percent_Identity=50.1193317422434, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1788737, Length=406, Percent_Identity=31.2807881773399, Blast_Score=192, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71991794, Length=419, Percent_Identity=33.890214797136, Blast_Score=241, Evalue=5e-64,
Organism=Caenorhabditis elegans, GI17560276, Length=396, Percent_Identity=33.3333333333333, Blast_Score=232, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI25146537, Length=216, Percent_Identity=32.8703703703704, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI45552519, Length=412, Percent_Identity=36.8932038834951, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI45552517, Length=412, Percent_Identity=36.8932038834951, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI19921868, Length=412, Percent_Identity=36.8932038834951, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI281360430, Length=413, Percent_Identity=36.0774818401937, Blast_Score=233, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y519_HAEIN (P44742)

Other databases:

- EMBL:   L42023
- PIR:   A64154
- RefSeq:   NP_438677.1
- GeneID:   949656
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0519
- TIGR:   HI_0519
- HOGENOM:   HBG713614
- OMA:   TQSELHA
- ProtClustDB:   CLSK808416
- BioCyc:   HINF71421:HI_0519-MONOMER
- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668
- PANTHER:   PTHR10590
- TIGRFAMs:   TIGR00804

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N

EC number: NA

Molecular weight: Translated: 42773; Mature: 42642

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12612a98)-; HASH(0x12c3422c)-; HASH(0x12dbdd1c)-; HASH(0xc48f910)-; HASH(0x12dcedfc)-; HASH(0x12a34544)-; HASH(0x12de81f4)-; HASH(0x12622d7c)-; HASH(0x124ee664)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLSSILGMVVLIAIAVLLSNNRKAISIRTVVGALAIQVGFAALILYVPAGKQALGAAA
CHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
DMVSNVIAYGNDGINFVFGGLADPSKPSGFIFAVKVLPIIVFFSGLISVLYYLGIMQVVI
HHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVLGGALQKALGTSKAESMSAAANIFVGQTEAPLVVRPYIKNMTQSELFAIMVGGTASIA
HHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCEEEEHHHHCCCHHHEEEEEECCHHHHH
GSVMAGYAGMGVPLTYLIAASFMAAPAGLLFAKLMFPQTEQFTDKQPEDNDSEKPTNVLE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHHHHH
AMAGGASAGMQLALNVGAMLIAFVGLIALINGILSGVGGWFGYGDLTLQSIFGLIFKPLA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHH
YLIGVTDGAEAGIAGQMIGMKLAVNEFVGYLEFAKYLQPDSAIVLTEKTKAIITFALCGF
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHC
ANFSSIAILIGGLGGMAPSRRSDVARLGIKAVIAGTLANLMSATIAGLFIGLGAAAL
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
SVLSSILGMVVLIAIAVLLSNNRKAISIRTVVGALAIQVGFAALILYVPAGKQALGAAA
HHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
DMVSNVIAYGNDGINFVFGGLADPSKPSGFIFAVKVLPIIVFFSGLISVLYYLGIMQVVI
HHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVLGGALQKALGTSKAESMSAAANIFVGQTEAPLVVRPYIKNMTQSELFAIMVGGTASIA
HHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCEEEEHHHHCCCHHHEEEEEECCHHHHH
GSVMAGYAGMGVPLTYLIAASFMAAPAGLLFAKLMFPQTEQFTDKQPEDNDSEKPTNVLE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHHHHH
AMAGGASAGMQLALNVGAMLIAFVGLIALINGILSGVGGWFGYGDLTLQSIFGLIFKPLA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHH
YLIGVTDGAEAGIAGQMIGMKLAVNEFVGYLEFAKYLQPDSAIVLTEKTKAIITFALCGF
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHC
ANFSSIAILIGGLGGMAPSRRSDVARLGIKAVIAGTLANLMSATIAGLFIGLGAAAL
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800