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The map label for this gene is nfuA

Identifier: 148827630

GI number: 148827630

Start: 979284

End: 979880

Strand: Reverse

Name: nfuA

Synonym: CGSHiGG_05385

Alternate gene names: 148827630

Gene position: 979880-979284 (Counterclockwise)

Preceding gene: 148827631

Following gene: 148827629

Centisome position: 51.92

GC content: 39.7

Gene sequence:

>597_bases
ATGGAACAAGCAACCCAGCAAATCGCTATTTCTGATGCCGCACAAGCGCATTTTCGAAAACTTTTAGACACGCAAGAAGA
AGGAACGAATATTCGTATTTTCGTCGTTAATCCGGGTACGCCTAATGCGGAATGTGGCGTATCTTATTGCCCCCCGAATG
CCGTGGAAGAAAGCGATATTGAAATGAAATATAATACTTTTTCTGCATTTATTGATGAAGTGAGTTTGCCTTTCTTAGAA
GAAGCAGAAATTGATTATGTTACCGAAGAGCTTGGTGCGCAACTGACCTTAAAAGCACCGAATGCCAAAATGCGTAAGGT
GGCTGATGATGCGCCATTAATTGAACGTGTTGAATATGTAATTCAAACTCAAATTAACCCACAGCTTGCAAATCACGGTG
GACGTATAACCTTAATTGAAATTACTGAAGATGGTTACGCAGTTTTACAATTTGGTGGTGGCTGTAACGGTTGTTCAATG
GTGGACGTTACGTTAAAAGATGGCGTAGAAAAACAACTTGTTAGCTTATTCCCGAATGAATTAAAAGGTGCAAAAGATAT
AACTGAGCATCAACGTGGCGAACATTCTTATTATTAG

Upstream 100 bases:

>100_bases
AGTGTGGGGGCTGGCGCGAGCTTAATATAAAGCACTGGAAAAAAAAGCGCGATAAGCGTATTATTCCCGATACTTTCTCT
CAAGTATTTAGGACATAATT

Downstream 100 bases:

>100_bases
TGAGTTATAAAAGAAGATTTATAATGACCGCACTTTTGAAAGTGCGGTTATTTTTATGGAGAAAAAATGAAAATACTTCA
ACAAGATGATTTTGGTTATT

Product: putative DNA uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MEQATQQIAISDAAQAHFRKLLDTQEEGTNIRIFVVNPGTPNAECGVSYCPPNAVEESDIEMKYNTFSAFIDEVSLPFLE
EAEIDYVTEELGAQLTLKAPNAKMRKVADDAPLIERVEYVIQTQINPQLANHGGRITLIEITEDGYAVLQFGGGCNGCSM
VDVTLKDGVEKQLVSLFPNELKGAKDITEHQRGEHSYY

Sequences:

>Translated_198_residues
MEQATQQIAISDAAQAHFRKLLDTQEEGTNIRIFVVNPGTPNAECGVSYCPPNAVEESDIEMKYNTFSAFIDEVSLPFLE
EAEIDYVTEELGAQLTLKAPNAKMRKVADDAPLIERVEYVIQTQINPQLANHGGRITLIEITEDGYAVLQFGGGCNGCSM
VDVTLKDGVEKQLVSLFPNELKGAKDITEHQRGEHSYY
>Mature_198_residues
MEQATQQIAISDAAQAHFRKLLDTQEEGTNIRIFVVNPGTPNAECGVSYCPPNAVEESDIEMKYNTFSAFIDEVSLPFLE
EAEIDYVTEELGAQLTLKAPNAKMRKVADDAPLIERVEYVIQTQINPQLANHGGRITLIEITEDGYAVLQFGGGCNGCSM
VDVTLKDGVEKQLVSLFPNELKGAKDITEHQRGEHSYY

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family

Homologues:

Organism=Escherichia coli, GI1789819, Length=191, Percent_Identity=75.9162303664921, Blast_Score=323, Evalue=6e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NFUA_HAEI8 (Q4QNB2)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_248145.1
- ProteinModelPortal:   Q4QNB2
- STRING:   Q4QNB2
- GeneID:   3429871
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI0558
- eggNOG:   COG0316
- HOGENOM:   HBG289644
- OMA:   CQGCSAV
- PhylomeDB:   Q4QNB2
- ProtClustDB:   PRK11190
- BioCyc:   HINF281310:NTHI0558-MONOMER
- HAMAP:   MF_01637
- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- ProDom:   PD002830
- TIGRFAMs:   TIGR03341

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 21884; Mature: 21884

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQATQQIAISDAAQAHFRKLLDTQEEGTNIRIFVVNPGTPNAECGVSYCPPNAVEESDI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCCC
EMKYNTFSAFIDEVSLPFLEEAEIDYVTEELGAQLTLKAPNAKMRKVADDAPLIERVEYV
EEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEECCCCHHHHHCCCCHHHHHHHHH
IQTQINPQLANHGGRITLIEITEDGYAVLQFGGGCNGCSMVDVTLKDGVEKQLVSLFPNE
HHHCCCHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHCHHH
LKGAKDITEHQRGEHSYY
CCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MEQATQQIAISDAAQAHFRKLLDTQEEGTNIRIFVVNPGTPNAECGVSYCPPNAVEESDI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCCC
EMKYNTFSAFIDEVSLPFLEEAEIDYVTEELGAQLTLKAPNAKMRKVADDAPLIERVEYV
EEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEECCCCHHHHHCCCCHHHHHHHHH
IQTQINPQLANHGGRITLIEITEDGYAVLQFGGGCNGCSMVDVTLKDGVEKQLVSLFPNE
HHHCCCHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHCHHH
LKGAKDITEHQRGEHSYY
CCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA