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The map label for this gene is htpG [H]

Identifier: 148827245

GI number: 148827245

Start: 558217

End: 560097

Strand: Reverse

Name: htpG [H]

Synonym: CGSHiGG_03065

Alternate gene names: 148827245

Gene position: 560097-558217 (Counterclockwise)

Preceding gene: 148827249

Following gene: 148827244

Centisome position: 29.68

GC content: 38.38

Gene sequence:

>1881_bases
ATGTCACAAAATCAAGAAACTCGCGGCTTCCAATCTGAAGTCAAACAACTACTCCAATTAATGATTCATTCTTTGTACTC
TAACAAAGAAATTTTCTTACGTGAATTGATTTCTAATGCTTCTGATGCGGCAGATAAATTACGCTTTAAAGCACTTTCCA
ACCCTGCTTTATATGAAGGCGATGGCGACTTGCGTGTGCGTGTTAGCTTTGATGCGGATAAAGGCATTATCACAATTAGC
GATAACGGCATTGGCATGACCCGTGAGCAAGTCATCGATCATTTGGGTACGATTGCAAAATCAGGAACAAAAGAATTTTT
AACCGCACTTGGTCAAGATCAAGCAAAAAATAGCCAGCTTATTGGGCAATTTGGCGTGGGTTTTTATTCTGCTTTTATTG
TGGCAGATAAAGTGACTGTAAAAACCAGAGCGGCTGGTGAAGAGGCGGATAAAGCTGTACTTTGGGAATCTGCGGGCGAA
GGCGAATATTCTGTGGCGGATATTGAGAAAAAATCCCGTGGTACAGATGTGATTTTACATTTACGTGAAGATGAAAAAGA
ATTTTTAAATGAATGGCGTTTGCGTGAAATTATTGGTAAATATTCTGACCATATTGGCTTGCCAGTGGAAATGCTGACGA
AAGAATACGATGATGAGGGCAAAGAGTGCGGTGAGAAATGGGAGAAAATTAATAAATCTGATGCCCTTTGGACGCGTTCT
AAAAATGATGTGTCCGATGAGGAATACAAAGCGTTTTACAAACACTTAAGCCATGATTTTTCTGATCCTGTGACTTGGGC
ACATAACAAAGTTGAGGGAAATCAAGCATATACTAGTTTGCTTTATGTACCAGCTAAAGCACCTTGGGATTTATTTAATC
GCGAACATAAACACGGCTTAAAACTTTATGTTCAACGTGTATTTATTATGGATGATGCTGAGCAATTTATGCCGAATTAT
CTACGTTTTATGCGTGGTTTAATCGATAGTAATGACTTGCCATTAAATGTATCTCGTGAAATTTTACAGGATAACAAAAT
TACGGCTGCACTACGCAAAGCATTAACTAAGCGTTCATTACAAATGCTAGAAAAATTAGCAAAAGATGATGCAGAAAAAT
ATCTTCAATTCTGGAAAGAGTTTGGTTTAGTCTTAAAAGAAGGCCCTGCAGAAGATTTTGCTAACAAAGAAACTATCGCA
AAGTTATTGCGTTTTGCTTCGACACATAATGATGGTTGCGAGCAAACTGTCTCTTTAGAAGATTACATCTTGCGTATGAA
AGAGGGGCAAAAAGCTATCTATTACATTACAGCGGATAGTTATGTTGCAGCGAAAAATAGCCCGCACTTGGAATTATTCA
ATAAAAAAGGCATTGAGGTTTTATTGCTTTCCGATCGCATTGATGAATGGATGTTAAGCTATTTAACTGAATTTGACGGT
AAACAATTACAAAGTATCACGAAAGCAGATTTGGATTTAGGCGATTTAGCCGATAAAGAATCTGAAACGCAAAAACAACG
AGATGAAGCCTTTGGTAGTTTTATTGAGCGTGTGAAAAACTTGCTTGGCGAACGTGTGAAAACGGTGCGTTTAACTCACA
ATTTAACGGATACACCAGCGGTGGTTTCTACGGATAACGATCAAATGACGACCCAAATGGCGAAATTGTTTGCAGCCGCA
GGGCAACCTGTACCAGAAGTAAAATACACATTTGAACTGAATCCAGAACACCATTTAGTGAAAAAAGTGGCTGATATTGC
AGATGAAATTGAATTTGCTGATTGGGTGGAACTGTTGCTTGAACAAGCTATGTTAGCAGAGCGCGGATCTTTGGAAAATC
CAGCTGCGTTTATTAAACGTATCAATAAGTTGTTAGGTTAA

Upstream 100 bases:

>100_bases
TGTTTTTTACCGCACTTTTCCTCTTAAATTTCCCTTGAAATCTTTCTTTTTATTCTTATATCTGTGACGTTCAATTTTTA
TCTTTATGAAGGAAAAAATT

Downstream 100 bases:

>100_bases
TTCATTTGAGATGAAGTAGTATAAGGGTTAAAATCCTCAATCTGATTAGATTGAGGATTTTTCTTTTTTAGGTGAAATAT
GATTACAGTTTACGGCATTA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 626; Mature: 625

Protein sequence:

>626_residues
MSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGDLRVRVSFDADKGIITIS
DNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGE
GEYSVADIEKKSRGTDVILHLREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRS
KNDVSDEEYKAFYKHLSHDFSDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAEQFMPNY
LRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPAEDFANKETIA
KLLRFASTHNDGCEQTVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
KQLQSITKADLDLGDLADKESETQKQRDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPAVVSTDNDQMTTQMAKLFAAA
GQPVPEVKYTFELNPEHHLVKKVADIADEIEFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG

Sequences:

>Translated_626_residues
MSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGDLRVRVSFDADKGIITIS
DNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGE
GEYSVADIEKKSRGTDVILHLREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRS
KNDVSDEEYKAFYKHLSHDFSDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAEQFMPNY
LRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPAEDFANKETIA
KLLRFASTHNDGCEQTVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
KQLQSITKADLDLGDLADKESETQKQRDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPAVVSTDNDQMTTQMAKLFAAA
GQPVPEVKYTFELNPEHHLVKKVADIADEIEFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG
>Mature_625_residues
SQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGDLRVRVSFDADKGIITISD
NGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGEG
EYSVADIEKKSRGTDVILHLREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRSK
NDVSDEEYKAFYKHLSHDFSDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAEQFMPNYL
RFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPAEDFANKETIAK
LLRFASTHNDGCEQTVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDGK
QLQSITKADLDLGDLADKESETQKQRDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPAVVSTDNDQMTTQMAKLFAAAG
QPVPEVKYTFELNPEHHLVKKVADIADEIEFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=681, Percent_Identity=37.5917767988253, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI4507677, Length=684, Percent_Identity=35.5263157894737, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI155722983, Length=630, Percent_Identity=36.3492063492063, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=37.0731707317073, Blast_Score=265, Evalue=1e-70,
Organism=Homo sapiens, GI153792590, Length=410, Percent_Identity=37.0731707317073, Blast_Score=263, Evalue=4e-70,
Organism=Escherichia coli, GI1786679, Length=623, Percent_Identity=75.2808988764045, Blast_Score=984, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=672, Percent_Identity=37.0535714285714, Blast_Score=445, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17542208, Length=671, Percent_Identity=35.9165424739195, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI115535205, Length=648, Percent_Identity=33.179012345679, Blast_Score=323, Evalue=2e-88,
Organism=Caenorhabditis elegans, GI115535167, Length=435, Percent_Identity=36.3218390804598, Blast_Score=270, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6323840, Length=676, Percent_Identity=38.6094674556213, Blast_Score=458, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6325016, Length=680, Percent_Identity=38.0882352941176, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI17647529, Length=689, Percent_Identity=36.7198838896952, Blast_Score=447, Evalue=1e-126,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=37.8854625550661, Blast_Score=394, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24586016, Length=646, Percent_Identity=33.9009287925697, Blast_Score=343, Evalue=2e-94,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71224; Mature: 71093

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEC
DGDLRVRVSFDADKGIITISDNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQL
CCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHH
IGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGEGEYSVADIEKKSRGTDVILH
HHHHHHHHHHHHHHHCCEEEEECCCCCHHCHHHEECCCCCCCEEHHHHHHHCCCCEEEEE
LREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRS
ECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECC
KNDVSDEEYKAFYKHLSHDFSDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGL
CCCCCHHHHHHHHHHHHCCCCCCCHHCCCCCCCCHHEEEEEEECCCCCHHHHCCHHHHHH
KLYVQRVFIMDDAEQFMPNYLRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
QMLEKLAKDDAEKYLQFWKEFGLVLKEGPAEDFANKETIAKLLRFASTHNDGCEQTVSLE
HHHHHHHHHHHHHHHHHHHHHCHHCCCCCCHHHCCHHHHHHHHHHHHCCCCCHHHHCCHH
DYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
HHHHHHHCCCEEEEEEEECCEEECCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHCCC
KQLQSITKADLDLGDLADKESETQKQRDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPA
HHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
VVSTDNDQMTTQMAKLFAAAGQPVPEVKYTFELNPEHHLVKKVADIADEIEFADWVELLL
EEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
EQAMLAERGSLENPAAFIKRINKLLG
HHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEG
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEC
DGDLRVRVSFDADKGIITISDNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQL
CCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHH
IGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGEGEYSVADIEKKSRGTDVILH
HHHHHHHHHHHHHHHCCEEEEECCCCCHHCHHHEECCCCCCCEEHHHHHHHCCCCEEEEE
LREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRS
ECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECC
KNDVSDEEYKAFYKHLSHDFSDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGL
CCCCCHHHHHHHHHHHHCCCCCCCHHCCCCCCCCHHEEEEEEECCCCCHHHHCCHHHHHH
KLYVQRVFIMDDAEQFMPNYLRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
QMLEKLAKDDAEKYLQFWKEFGLVLKEGPAEDFANKETIAKLLRFASTHNDGCEQTVSLE
HHHHHHHHHHHHHHHHHHHHHCHHCCCCCCHHHCCHHHHHHHHHHHHCCCCCHHHHCCHH
DYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
HHHHHHHCCCEEEEEEEECCEEECCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHCCC
KQLQSITKADLDLGDLADKESETQKQRDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPA
HHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
VVSTDNDQMTTQMAKLFAAAGQPVPEVKYTFELNPEHHLVKKVADIADEIEFADWVELLL
EEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
EQAMLAERGSLENPAAFIKRINKLLG
HHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8972900 [H]