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The map label for this gene is lolC [H]

Identifier: 148826789

GI number: 148826789

Start: 26303

End: 27379

Strand: Direct

Name: lolC [H]

Synonym: CGSHiGG_00180

Alternate gene names: 148826789

Gene position: 26303-27379 (Clockwise)

Preceding gene: 148826788

Following gene: 148826790

Centisome position: 1.39

GC content: 39.55

Gene sequence:

>1077_bases
ATGAATTTTCCTATTTCTCTTTATATTGCACTACGTTATTGGCGTGCGAAAAGTGCGGATCGTTTTGGGCGATTAGTGAC
TAATCTTGCAAGCCTGGGGATTGTGCTAGGTGTAATGGCATTGATCATCGTGCTTTCGGTGATGAATGGATTAGAAGGTT
ACCAAAAACAACAGGTGCTATCTTCTATTCCTCATGCGATTGTGAGCGAAGAGCAGCCTATTTCTACAGAAAAAACGCTA
GAAAATTTACCGCACTTTGTCCAAAAAGCCGTGCCGATCAATACAACAAATGTGATTTATCAAACGGCAAAAGGCGTAAG
TGCAGGACAAATTATAGGTATTCAATCATTTTCTGATGATCCTTTGGTTGAATCTTTTGATCAGACTAAATTTAATGAAA
TTTTACCTAGTGGGGAGTTTAAACTGGTCATTGGCGATCAACTGGCGCAAAAACTGGGCGTGAATATTGGGGATAAAATC
CGTTTGATGATTACGGAAAATAGCCAATATACACCATTCGGTCGGGTGCCAATGCAGCGTTTGTTTACTGTTAGCGATAT
TTATTATGGTTATGGCGAAGCATCTGGTTACGAAGCCTTTGCTAATATTACAGATATTGGTCGCTTAATGCGTATTCAAC
CTCAGCAAGCGCAGGGCTATCGTTTATTTCTGAATGATCCGTTCCAAATTACAGAACTCCCACAACATTTCTCAACACAA
AAAATCACGGATTGGCGTGTGCAAAAAGGCGAATTTTTCCAAGCGGTGAGAATGGAAAAAAATATGATGGGATTGCTGAT
TAGTTTGATTATTGTTGTGGCGATTTCCAATATTGTCACCTCTTTAAGTTTGATGGTGGTGGATAAACAAGGGGAAATTG
CGATTTTGCAAACTCAGGGCTTAACAAAATCCCAAGTTCGTTCGGTGTTCATTTATCAAGGATTACTGGTGGGATTTGTT
GGCACATTGCTCGGTGCTATTTTAGGTGTTTTAGCTACGTTGAACTTAACAGAGATTGTAAGTGCGGTAAATCCTCAAGG
TGTTTTTTACCGACAGAATTATCCTTTGTTCAAATGA

Upstream 100 bases:

>100_bases
CCCCGCATATTGCTTGGGCGAGCGATAGTGCAGTGACAACATTAGTTGGCAAAGTAATGCAAAACATCGAAGAATTTGTA
CAACAATTACATCAAAAATA

Downstream 100 bases:

>100_bases
TTTTTGTCATTGGATTTTCGCTGTTACTTTCCTTGCTTTCAACCCTTTATCCTGCTTATCGAGCTGCGAAAGTAGAACCT
GCAGCAGCTTTGAGATACGA

Product: glycerate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MNFPISLYIALRYWRAKSADRFGRLVTNLASLGIVLGVMALIIVLSVMNGLEGYQKQQVLSSIPHAIVSEEQPISTEKTL
ENLPHFVQKAVPINTTNVIYQTAKGVSAGQIIGIQSFSDDPLVESFDQTKFNEILPSGEFKLVIGDQLAQKLGVNIGDKI
RLMITENSQYTPFGRVPMQRLFTVSDIYYGYGEASGYEAFANITDIGRLMRIQPQQAQGYRLFLNDPFQITELPQHFSTQ
KITDWRVQKGEFFQAVRMEKNMMGLLISLIIVVAISNIVTSLSLMVVDKQGEIAILQTQGLTKSQVRSVFIYQGLLVGFV
GTLLGAILGVLATLNLTEIVSAVNPQGVFYRQNYPLFK

Sequences:

>Translated_358_residues
MNFPISLYIALRYWRAKSADRFGRLVTNLASLGIVLGVMALIIVLSVMNGLEGYQKQQVLSSIPHAIVSEEQPISTEKTL
ENLPHFVQKAVPINTTNVIYQTAKGVSAGQIIGIQSFSDDPLVESFDQTKFNEILPSGEFKLVIGDQLAQKLGVNIGDKI
RLMITENSQYTPFGRVPMQRLFTVSDIYYGYGEASGYEAFANITDIGRLMRIQPQQAQGYRLFLNDPFQITELPQHFSTQ
KITDWRVQKGEFFQAVRMEKNMMGLLISLIIVVAISNIVTSLSLMVVDKQGEIAILQTQGLTKSQVRSVFIYQGLLVGFV
GTLLGAILGVLATLNLTEIVSAVNPQGVFYRQNYPLFK
>Mature_358_residues
MNFPISLYIALRYWRAKSADRFGRLVTNLASLGIVLGVMALIIVLSVMNGLEGYQKQQVLSSIPHAIVSEEQPISTEKTL
ENLPHFVQKAVPINTTNVIYQTAKGVSAGQIIGIQSFSDDPLVESFDQTKFNEILPSGEFKLVIGDQLAQKLGVNIGDKI
RLMITENSQYTPFGRVPMQRLFTVSDIYYGYGEASGYEAFANITDIGRLMRIQPQQAQGYRLFLNDPFQITELPQHFSTQ
KITDWRVQKGEFFQAVRMEKNMMGLLISLIIVVAISNIVTSLSLMVVDKQGEIAILQTQGLTKSQVRSVFIYQGLLVGFV
GTLLGAILGVLATLNLTEIVSAVNPQGVFYRQNYPLFK

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=317, Percent_Identity=47.9495268138801, Blast_Score=291, Evalue=6e-80,
Organism=Escherichia coli, GI1787362, Length=355, Percent_Identity=28.7323943661972, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 39839; Mature: 39839

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPISLYIALRYWRAKSADRFGRLVTNLASLGIVLGVMALIIVLSVMNGLEGYQKQQVL
CCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSIPHAIVSEEQPISTEKTLENLPHFVQKAVPINTTNVIYQTAKGVSAGQIIGIQSFSDD
HHCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEECCCCCC
PLVESFDQTKFNEILPSGEFKLVIGDQLAQKLGVNIGDKIRLMITENSQYTPFGRVPMQR
HHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHH
LFTVSDIYYGYGEASGYEAFANITDIGRLMRIQPQQAQGYRLFLNDPFQITELPQHFSTQ
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHCHHHHCCC
KITDWRVQKGEFFQAVRMEKNMMGLLISLIIVVAISNIVTSLSLMVVDKQGEIAILQTQG
CCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECC
LTKSQVRSVFIYQGLLVGFVGTLLGAILGVLATLNLTEIVSAVNPQGVFYRQNYPLFK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure
MNFPISLYIALRYWRAKSADRFGRLVTNLASLGIVLGVMALIIVLSVMNGLEGYQKQQVL
CCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSIPHAIVSEEQPISTEKTLENLPHFVQKAVPINTTNVIYQTAKGVSAGQIIGIQSFSDD
HHCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEECCCCCC
PLVESFDQTKFNEILPSGEFKLVIGDQLAQKLGVNIGDKIRLMITENSQYTPFGRVPMQR
HHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHH
LFTVSDIYYGYGEASGYEAFANITDIGRLMRIQPQQAQGYRLFLNDPFQITELPQHFSTQ
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHCHHHHCCC
KITDWRVQKGEFFQAVRMEKNMMGLLISLIIVVAISNIVTSLSLMVVDKQGEIAILQTQG
CCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECC
LTKSQVRSVFIYQGLLVGFVGTLLGAILGVLATLNLTEIVSAVNPQGVFYRQNYPLFK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]