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The map label for this gene is aspC [H]

Identifier: 148826143

GI number: 148826143

Start: 1148976

End: 1150166

Strand: Direct

Name: aspC [H]

Synonym: CGSHiEE_05750

Alternate gene names: 148826143

Gene position: 1148976-1150166 (Clockwise)

Preceding gene: 148826142

Following gene: 148826149

Centisome position: 63.37

GC content: 40.05

Gene sequence:

>1191_bases
ATGTTTGAACATATTAAAGCGGCACCAGCCGATCCAATCTTAGGCTTAGGCGAAGCATTCAAATCCGAAACTCGCGAAAA
TAAAATTAACTTGGGTATTGGCGTTTATAAAGATGCGCAAGGCACAACCCCGATTATGCGTGCAGTGAAAGAAGCAGAAA
AACGCTTATTTGATAAGGAAAAAACGAAAAATTATCTGACTATCGATGGTATTGCTGATTATAACGAACAAACAAAAGCG
TTACTTTTCGGTAAAGATTCTGAAGTCATCAAATCTAATCGTGCAAGAACAGTACAAAGTTTAGGCGGAACAGGCGCATT
ACGCATTGCGGCAGAATTTATTAAACGTCAAACTAAAGCACAAAATGTTTGGATCAGCACCCCAACTTGGCCAAACCACA
ATGCCATTTTCAATGCCGTCGGTATGACAATTCGTGAATATCGTTATTATGATGCTGAACGCAAAGCCCTTGATTGGGAT
CATTTACTTGAAGATTTAAGCCAAGCAAGCGAAGGCGATGTGGTGCTTTTACACGGTTGTTGCCATAATCCGACTGGTAT
TGACCCTACTCCAGAACAATGGCAAGAATTAGCCGCACTTTCGGCGAAAAACGGCTGGTTGCCACTCTTTGACTTTGCTT
ATCAAGGTTTAGCCAATGGATTAGATGAAGATGCTTATGGCTTGCGTGCTTTTGCGGCAAACCACAAAGAATTGTTAGTA
GCGAGTTCATTCTCGAAAAACTTTGGTTTATATAATGAACGTGTTGGTGCCTTTACTCTTGTGGCAGAAAATGCAGAAAT
TGCATCAACCGCATTAACCCAAGTGAAATCAATTATTCGTACACTCTACTCTAACCCTGCATCTCACGGCGGCGCAACTG
TAGCAACAGTATTAAATGACACTCAACTTCGCCAAGAGTGGGAAAATGAATTAACTGAAATGCGCGAACGTATCAAAAAA
ATGCGTCATTTATTCGTTCAGTTATTAAAAGAATACGGTGCGGAACAAGATTTCAGCTTTATCATTGAACAAAACGGTAT
GTTCTCTTTCAGTGGATTAACTGGGGAACAAGTGGATCGCTTAAAAGAAGAATTTGCCATTTATGCTGTTCGTTCTGGTC
GTATCAATGTGGCTGGTATTACTGAAGATAATATTCGCTATTTATGTGAAAGCATTGTGAAAGTGCTTTAA

Upstream 100 bases:

>100_bases
TATTAAAGTGCGGTTAATTTTTATAAAAATCTTTCTTGATAAAATAAAACGGCTGAAGTATAAAATTATCCATCACACAA
CTGATACATAAGGAAAAGCT

Downstream 100 bases:

>100_bases
TAGGGTTAGAAATAATATATCCTCTAAAATATTGTAAGTAAAAAATAAAGCCTTGATTATCAAGGCTTTAATTTTATTTA
ATCATTAACAAATTCTCGGC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MFEHIKAAPADPILGLGEAFKSETRENKINLGIGVYKDAQGTTPIMRAVKEAEKRLFDKEKTKNYLTIDGIADYNEQTKA
LLFGKDSEVIKSNRARTVQSLGGTGALRIAAEFIKRQTKAQNVWISTPTWPNHNAIFNAVGMTIREYRYYDAERKALDWD
HLLEDLSQASEGDVVLLHGCCHNPTGIDPTPEQWQELAALSAKNGWLPLFDFAYQGLANGLDEDAYGLRAFAANHKELLV
ASSFSKNFGLYNERVGAFTLVAENAEIASTALTQVKSIIRTLYSNPASHGGATVATVLNDTQLRQEWENELTEMRERIKK
MRHLFVQLLKEYGAEQDFSFIIEQNGMFSFSGLTGEQVDRLKEEFAIYAVRSGRINVAGITEDNIRYLCESIVKVL

Sequences:

>Translated_396_residues
MFEHIKAAPADPILGLGEAFKSETRENKINLGIGVYKDAQGTTPIMRAVKEAEKRLFDKEKTKNYLTIDGIADYNEQTKA
LLFGKDSEVIKSNRARTVQSLGGTGALRIAAEFIKRQTKAQNVWISTPTWPNHNAIFNAVGMTIREYRYYDAERKALDWD
HLLEDLSQASEGDVVLLHGCCHNPTGIDPTPEQWQELAALSAKNGWLPLFDFAYQGLANGLDEDAYGLRAFAANHKELLV
ASSFSKNFGLYNERVGAFTLVAENAEIASTALTQVKSIIRTLYSNPASHGGATVATVLNDTQLRQEWENELTEMRERIKK
MRHLFVQLLKEYGAEQDFSFIIEQNGMFSFSGLTGEQVDRLKEEFAIYAVRSGRINVAGITEDNIRYLCESIVKVL
>Mature_396_residues
MFEHIKAAPADPILGLGEAFKSETRENKINLGIGVYKDAQGTTPIMRAVKEAEKRLFDKEKTKNYLTIDGIADYNEQTKA
LLFGKDSEVIKSNRARTVQSLGGTGALRIAAEFIKRQTKAQNVWISTPTWPNHNAIFNAVGMTIREYRYYDAERKALDWD
HLLEDLSQASEGDVVLLHGCCHNPTGIDPTPEQWQELAALSAKNGWLPLFDFAYQGLANGLDEDAYGLRAFAANHKELLV
ASSFSKNFGLYNERVGAFTLVAENAEIASTALTQVKSIIRTLYSNPASHGGATVATVLNDTQLRQEWENELTEMRERIKK
MRHLFVQLLKEYGAEQDFSFIIEQNGMFSFSGLTGEQVDRLKEEFAIYAVRSGRINVAGITEDNIRYLCESIVKVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=43.9393939393939, Blast_Score=358, Evalue=3e-99,
Organism=Homo sapiens, GI4504067, Length=400, Percent_Identity=41.5, Blast_Score=317, Evalue=1e-86,
Organism=Homo sapiens, GI117414139, Length=380, Percent_Identity=29.4736842105263, Blast_Score=177, Evalue=1e-44,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=63.3838383838384, Blast_Score=542, Evalue=1e-155,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=42.0654911838791, Blast_Score=343, Evalue=9e-96,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=43.2911392405063, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=40.253164556962, Blast_Score=342, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI17569539, Length=395, Percent_Identity=37.2151898734177, Blast_Score=289, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17569537, Length=388, Percent_Identity=31.701030927835, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI25147136, Length=220, Percent_Identity=39.0909090909091, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=33.8403041825095, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=38.2716049382716, Blast_Score=301, Evalue=9e-83,
Organism=Saccharomyces cerevisiae, GI6322743, Length=427, Percent_Identity=31.8501170960187, Blast_Score=233, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=42.9292929292929, Blast_Score=344, Evalue=6e-95,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=42.9292929292929, Blast_Score=344, Evalue=7e-95,
Organism=Drosophila melanogaster, GI19920542, Length=390, Percent_Identity=43.3333333333333, Blast_Score=340, Evalue=7e-94,
Organism=Drosophila melanogaster, GI19922362, Length=395, Percent_Identity=39.2405063291139, Blast_Score=314, Evalue=7e-86,
Organism=Drosophila melanogaster, GI24654046, Length=395, Percent_Identity=39.2405063291139, Blast_Score=313, Evalue=9e-86,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44356; Mature: 44356

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEHIKAAPADPILGLGEAFKSETRENKINLGIGVYKDAQGTTPIMRAVKEAEKRLFDKE
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECEEEEECCCCCHHHHHHHHHHHHHHHHHH
KTKNYLTIDGIADYNEQTKALLFGKDSEVIKSNRARTVQSLGGTGALRIAAEFIKRQTKA
HCCCEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QNVWISTPTWPNHNAIFNAVGMTIREYRYYDAERKALDWDHLLEDLSQASEGDVVLLHGC
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCCCCEEEEECC
CHNPTGIDPTPEQWQELAALSAKNGWLPLFDFAYQGLANGLDEDAYGLRAFAANHKELLV
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHEEE
ASSFSKNFGLYNERVGAFTLVAENAEIASTALTQVKSIIRTLYSNPASHGGATVATVLND
EECCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHH
TQLRQEWENELTEMRERIKKMRHLFVQLLKEYGAEQDFSFIIEQNGMFSFSGLTGEQVDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCHHHHHH
LKEEFAIYAVRSGRINVAGITEDNIRYLCESIVKVL
HHHHHEEEEEECCEEEEEECCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MFEHIKAAPADPILGLGEAFKSETRENKINLGIGVYKDAQGTTPIMRAVKEAEKRLFDKE
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECEEEEECCCCCHHHHHHHHHHHHHHHHHH
KTKNYLTIDGIADYNEQTKALLFGKDSEVIKSNRARTVQSLGGTGALRIAAEFIKRQTKA
HCCCEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QNVWISTPTWPNHNAIFNAVGMTIREYRYYDAERKALDWDHLLEDLSQASEGDVVLLHGC
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCCCCEEEEECC
CHNPTGIDPTPEQWQELAALSAKNGWLPLFDFAYQGLANGLDEDAYGLRAFAANHKELLV
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHEEE
ASSFSKNFGLYNERVGAFTLVAENAEIASTALTQVKSIIRTLYSNPASHGGATVATVLND
EECCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHH
TQLRQEWENELTEMRERIKKMRHLFVQLLKEYGAEQDFSFIIEQNGMFSFSGLTGEQVDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCHHHHHH
LKEEFAIYAVRSGRINVAGITEDNIRYLCESIVKVL
HHHHHEEEEEECCEEEEEECCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]