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The map label for this gene is ycaJ [C]

Identifier: 148823755

GI number: 148823755

Start: 2891889

End: 2893247

Strand: Reverse

Name: ycaJ [C]

Synonym: TBFG_12580

Alternate gene names: 148823755

Gene position: 2893247-2891889 (Counterclockwise)

Preceding gene: 148823763

Following gene: 148823752

Centisome position: 65.39

GC content: 69.17

Gene sequence:

>1359_bases
ATGCCTGAAGCCGTGTCCGACGGTCTGTTTGACGTGCCCGGCGTACCGATGACGTCCGGCCATGACCTGGGCGCTTCGGC
CGGGGCACCGCTGGCGGTGCGGATGCGTCCGGCGTCGCTGGACGAAGTGGTCGGCCAGGACCACTTGCTGGCGCCCGGTT
CGCCGTTGCGCCGGCTGGTCGAGGGCTCGGGGGTGGCGTCGGTGATCCTCTACGGTCCCCCGGGCAGCGGCAAGACAACG
CTGGCGGCGTTGATCTCGCAGGCCACCGGCCGCCGGTTCGAGGCCCTGTCGGCATTGTCGGCCGGCGTCAAGGAAGTGCG
GGCGGTCATCGAGAATTCGCGAAAAGCGCTGCTTCACGGCGAGCAGACCGTGCTGTTCATCGACGAGGTGCACCGATTTT
CCAAGACCCAACAAGACGCCCTGCTGTCGGCGGTGGAACACCGGGTGGTGCTGTTGGTGGCGGCGACCACCGAGAACCCG
TCGTTTTCGGTGGTGGCACCGCTGCTGTCGCGGTCGCTGATCCTGCAGCTGCGGCCGCTGACGGCCGAGGACACCCGCGC
GGTAGTACAACGCGCGATCGATGACCCCCGCGGCCTGGGCAGGGCAGTCGCGGTAGCGCCTGAGGCCGTCGACCTGCTGG
TGCAACTCGCGGCCGGCGACGCCCGGCGCGCCCTGACCGCGCTGGAAGTAGCGGCCGAGGCAGCCCAGGCGGCCGGCGAG
CTGGTCAGCGTGCAAACCATCGAGCGGTCGGTGGACAAAGCCGCGGTGCGCTACGACCGTGACGGCGACCAGCACTACGA
CGTCGTCAGCGCCTTCATCAAATCGGTGCGCGGTTCCGACGTCGATGCCGCGCTGCACTATTTGGCCCGCATGCTGGTCG
CCGGGGAGGACCCGCGGTTCATCGCCCGCCGGCTGATGATTCTGGCCAGCGAGGACATCGGCATGGCCGGCCCGAGCGCG
CTGCAGGTGGCGGTCGCCGCCGCACAGACGGTGGCGCTGATCGGCATGCCCGAAGCCCAGCTGACGCTGGCGCACGCCAC
CATCCACCTGGCCACCGCACCGAAGTCAAACGCCGTCACCACGGCGTTGGCCGCGGCGATGAACGACATCAAGGCCGGCA
AGGCCGGTCTGGTGCCGGCTCATCTGCGTGACGGGCATTACTCCGGGGCGGCGGCGCTGGGCAATGCACAGGGCTACAAA
TATTCCCATGACGACCCGGATGGCGTTGTGGCCCAGCAATACCCGCCCGACGAGTTGGTGGACGTGGACTACTACCGGCC
CACTGGTCGCGGCGGCGAACGCGAGATCGCCGGCCGCCTGGACCGCCTGCGGGCAATCATCCGCAAGAAACGGGGGTGA

Upstream 100 bases:

>100_bases
GACGCTAAGCAAACCGGAACTTAGCAAATATTTGCCGAAGGCGCGCGGATTATTCGTGTGGCGTCTTCGGCGAACGTTCG
CGTCGTCAGGTGGGCGTGGT

Downstream 100 bases:

>100_bases
CCGCTGCGCTCTGCGGGAAGCAGGTCCGCTCAGACCAGCTCGGGTACCCGTAGATGTGCGATCGCCAGTTCGAATTCGGC
GACGTCGAGGACCTCGGCTC

Product: recombination factor protein RarA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MPEAVSDGLFDVPGVPMTSGHDLGASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASVILYGPPGSGKTT
LAALISQATGRRFEALSALSAGVKEVRAVIENSRKALLHGEQTVLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENP
SFSVVAPLLSRSLILQLRPLTAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARRALTALEVAAEAAQAAGE
LVSVQTIERSVDKAAVRYDRDGDQHYDVVSAFIKSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMAGPSA
LQVAVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVTTALAAAMNDIKAGKAGLVPAHLRDGHYSGAAALGNAQGYK
YSHDDPDGVVAQQYPPDELVDVDYYRPTGRGGEREIAGRLDRLRAIIRKKRG

Sequences:

>Translated_452_residues
MPEAVSDGLFDVPGVPMTSGHDLGASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASVILYGPPGSGKTT
LAALISQATGRRFEALSALSAGVKEVRAVIENSRKALLHGEQTVLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENP
SFSVVAPLLSRSLILQLRPLTAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARRALTALEVAAEAAQAAGE
LVSVQTIERSVDKAAVRYDRDGDQHYDVVSAFIKSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMAGPSA
LQVAVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVTTALAAAMNDIKAGKAGLVPAHLRDGHYSGAAALGNAQGYK
YSHDDPDGVVAQQYPPDELVDVDYYRPTGRGGEREIAGRLDRLRAIIRKKRG
>Mature_451_residues
PEAVSDGLFDVPGVPMTSGHDLGASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASVILYGPPGSGKTTL
AALISQATGRRFEALSALSAGVKEVRAVIENSRKALLHGEQTVLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENPS
FSVVAPLLSRSLILQLRPLTAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARRALTALEVAAEAAQAAGEL
VSVQTIERSVDKAAVRYDRDGDQHYDVVSAFIKSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMAGPSAL
QVAVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVTTALAAAMNDIKAGKAGLVPAHLRDGHYSGAAALGNAQGYKY
SHDDPDGVVAQQYPPDELVDVDYYRPTGRGGEREIAGRLDRLRAIIRKKRG

Specific function: Unknown

COG id: COG2256

COG function: function code L; ATPase related to the helicase subunit of the Holliday junction resolvase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family

Homologues:

Organism=Homo sapiens, GI18426902, Length=445, Percent_Identity=39.5505617977528, Blast_Score=287, Evalue=2e-77,
Organism=Homo sapiens, GI18426904, Length=445, Percent_Identity=36.6292134831461, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI4506491, Length=242, Percent_Identity=25.6198347107438, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI31881687, Length=242, Percent_Identity=25.6198347107438, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1787119, Length=428, Percent_Identity=42.5233644859813, Blast_Score=333, Evalue=9e-93,
Organism=Saccharomyces cerevisiae, GI6324111, Length=430, Percent_Identity=38.6046511627907, Blast_Score=273, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6324039, Length=229, Percent_Identity=26.6375545851528, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322528, Length=295, Percent_Identity=24.0677966101695, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI18859927, Length=216, Percent_Identity=27.3148148148148, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2559_MYCTU (Q50739)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   C70728
- RefSeq:   NP_217075.1
- RefSeq:   NP_337134.1
- ProteinModelPortal:   Q50739
- SMR:   Q50739
- EnsemblBacteria:   EBMYCT00000001276
- EnsemblBacteria:   EBMYCT00000071939
- GeneID:   887368
- GeneID:   925679
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2636
- KEGG:   mtu:Rv2559c
- TIGR:   MT2636
- TubercuList:   Rv2559c
- GeneTree:   EBGT00050000015332
- HOGENOM:   HBG635390
- OMA:   NKQYYKP
- ProtClustDB:   PRK13342
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR021886
- SMART:   SM00382

Pfam domain/function: PF00004 AAA; PF12002 MgsA_C

EC number: NA

Molecular weight: Translated: 47500; Mature: 47369

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEAVSDGLFDVPGVPMTSGHDLGASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCHHHHHHH
EGSGVASVILYGPPGSGKTTLAALISQATGRRFEALSALSAGVKEVRAVIENSRKALLHG
CCCCEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHEECC
EQTVLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENPSFSVVAPLLSRSLILQLRPL
CCEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHEEECCC
TAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARRALTALEVAAEAAQAAGE
CCHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LVSVQTIERSVDKAAVRYDRDGDQHYDVVSAFIKSVRGSDVDAALHYLARMLVAGEDPRF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHH
IARRLMILASEDIGMAGPSALQVAVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVT
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEECCCHHEEEEEEEEEEEECCCCCHHH
TALAAAMNDIKAGKAGLVPAHLRDGHYSGAAALGNAQGYKYSHDDPDGVVAQQYPPDELV
HHHHHHHHHHCCCCCCCCCHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCEECCCCCCCCE
DVDYYRPTGRGGEREIAGRLDRLRAIIRKKRG
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PEAVSDGLFDVPGVPMTSGHDLGASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCHHHHHHH
EGSGVASVILYGPPGSGKTTLAALISQATGRRFEALSALSAGVKEVRAVIENSRKALLHG
CCCCEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHEECC
EQTVLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENPSFSVVAPLLSRSLILQLRPL
CCEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHEEECCC
TAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARRALTALEVAAEAAQAAGE
CCHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LVSVQTIERSVDKAAVRYDRDGDQHYDVVSAFIKSVRGSDVDAALHYLARMLVAGEDPRF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHH
IARRLMILASEDIGMAGPSALQVAVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVT
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEECCCHHEEEEEEEEEEEECCCCCHHH
TALAAAMNDIKAGKAGLVPAHLRDGHYSGAAALGNAQGYKYSHDDPDGVVAQQYPPDELV
HHHHHHHHHHCCCCCCCCCHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCEECCCCCCCCE
DVDYYRPTGRGGEREIAGRLDRLRAIIRKKRG
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036