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The map label for this gene is espC

Identifier: 148663478

GI number: 148663478

Start: 4063259

End: 4063570

Strand: Reverse

Name: espC

Synonym: MRA_3651

Alternate gene names: 148663478

Gene position: 4063570-4063259 (Counterclockwise)

Preceding gene: 148663479

Following gene: 148663477

Centisome position: 91.94

GC content: 58.33

Gene sequence:

>312_bases
ATGACGGAAAACTTGACCGTCCAGCCCGAGCGTCTCGGTGTACTGGCGTCGCACCATGACAACGCGGCGGTCGATGCCTC
CTCGGGCGTCGAAGCTGCCGCTGGCCTAGGCGAATCTGTGGCGATCACTCACGGTCCGTACTGCTCACAGTTCAACGACA
CGTTAAATGTGTACTTGACTGCCCACAATGCCCTGGGCTCGTCCTTGCATACGGCCGGTGTCGATCTCGCCAAAAGTCTT
CGAATTGCGGCGAAGATATATAGCGAGGCCGACGAAGCGTGGCGCAAGGCTATCGACGGGTTGTTTACCTGA

Upstream 100 bases:

>100_bases
AAGGTGCTGGTACGAAACGTCGTCTAACGGCATGGCGAGCCAAATCCATTGCTAGCCAGCGCCTAACAACGCGCAATGCT
AAACGGAAGGGACACGATCA

Downstream 100 bases:

>100_bases
CCACGTTTGCTGCCCGCAGTGCAGGCCACAGCGTCTTCCCAACGACCTGTTCGGACTGACCACGCCAGCTGCCCAGGCCG
ACCCTTCCCGGGTGGCAATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 103; Mature: 102

Protein sequence:

>103_residues
MTENLTVQPERLGVLASHHDNAAVDASSGVEAAAGLGESVAITHGPYCSQFNDTLNVYLTAHNALGSSLHTAGVDLAKSL
RIAAKIYSEADEAWRKAIDGLFT

Sequences:

>Translated_103_residues
MTENLTVQPERLGVLASHHDNAAVDASSGVEAAAGLGESVAITHGPYCSQFNDTLNVYLTAHNALGSSLHTAGVDLAKSL
RIAAKIYSEADEAWRKAIDGLFT
>Mature_102_residues
TENLTVQPERLGVLASHHDNAAVDASSGVEAAAGLGESVAITHGPYCSQFNDTLNVYLTAHNALGSSLHTAGVDLAKSLR
IAAKIYSEADEAWRKAIDGLFT

Specific function: Required for ESX-1 secretion. Required for either stability or expression of EspA

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=Secreted via the ESX-1 / type VII secretion system (T7SS)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EspC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ESPC_MYCTU (P65087)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   H70956
- RefSeq:   NP_218132.1
- RefSeq:   NP_338262.1
- EnsemblBacteria:   EBMYCT00000001162
- EnsemblBacteria:   EBMYCT00000069625
- GeneID:   885770
- GeneID:   926517
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3717
- KEGG:   mtu:Rv3615c
- TIGR:   MT3717
- TubercuList:   Rv3615c
- GeneTree:   EBGT00050000018422
- HOGENOM:   HBG569622
- OMA:   MYESTRS
- ProtClustDB:   CLSK792597
- GO:   GO:0009405
- InterPro:   IPR022536

Pfam domain/function: PF10824 DUF2580

EC number: NA

Molecular weight: Translated: 10795; Mature: 10664

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENLTVQPERLGVLASHHDNAAVDASSGVEAAAGLGESVAITHGPYCSQFNDTLNVYLT
CCCCCCCCHHHHCEEECCCCCCCCCCCCCCHHHHCCCCCEEEECCCCCCCCCCCEEEEEE
AHNALGSSLHTAGVDLAKSLRIAAKIYSEADEAWRKAIDGLFT
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TENLTVQPERLGVLASHHDNAAVDASSGVEAAAGLGESVAITHGPYCSQFNDTLNVYLT
CCCCCCCHHHHCEEECCCCCCCCCCCCCCHHHHCCCCCEEEECCCCCCCCCCCEEEEEE
AHNALGSSLHTAGVDLAKSLRIAAKIYSEADEAWRKAIDGLFT
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036