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The map label for this gene is espD

Identifier: 148663477

GI number: 148663477

Start: 4062589

End: 4063143

Strand: Reverse

Name: espD

Synonym: MRA_3650

Alternate gene names: 148663477

Gene position: 4063143-4062589 (Counterclockwise)

Preceding gene: 148663478

Following gene: 148663476

Centisome position: 91.93

GC content: 62.34

Gene sequence:

>555_bases
GTGGACTTGCCCGGAAATGACTTTGACAGCAACGATTTCGACGCCGTGGATCTCTGGGGTGCCGACGGCGCGGAGGGCTG
GACTGCGGATCCGATTATTGGCGTCGGGTCGGCGGCGACCCCGGACACCGGACCCGACCTGGACAATGCCCACGGTCAGG
CGGAGACGGACACCGAACAAGAGATCGCGCTTTTTACCGTGACGAATCCCCCACGCACGGTGTCGGTATCGACGCTGATG
GACGGCCGGATTGACCATGTCGAGCTGTCGGCCAGGGTGGCCTGGATGAGTGAGTCGCAGCTCGCTTCTGAGATCCTGGT
GATTGCCGACCTGGCGCGGCAGAAGGCGCAGTCGGCCCAGTACGCCTTCATCCTTGACAGGATGAGTCAACAGGTCGATG
CAGATGAACACCGCGTCGCACTGCTACGTAAGACCGTGGGCGAAACCTGGGGGTTACCATCGCCGGAAGAAGCCGCGGCA
GCAGAAGCTGAGGTGTTCGCGACGCGCTACAGCGACGATTGTCCAGCACCAGACGACGAGAGCGATCCATGGTGA

Upstream 100 bases:

>100_bases
GCAGTGCAGGCCACAGCGTCTTCCCAACGACCTGTTCGGACTGACCACGCCAGCTGCCCAGGCCGACCCTTCCCGGGTGG
CAATGAATTCCGAAGGGACG

Downstream 100 bases:

>100_bases
GTTGAACCGCCCCGGCCGCTGCGGTGACTCTGGTGCTCCGCGTGTTTCCCGACTGGGCTCACAATTCGCGGCTCAGCATT
AATAGAGCACGGGTGGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MDLPGNDFDSNDFDAVDLWGADGAEGWTADPIIGVGSAATPDTGPDLDNAHGQAETDTEQEIALFTVTNPPRTVSVSTLM
DGRIDHVELSARVAWMSESQLASEILVIADLARQKAQSAQYAFILDRMSQQVDADEHRVALLRKTVGETWGLPSPEEAAA
AEAEVFATRYSDDCPAPDDESDPW

Sequences:

>Translated_184_residues
MDLPGNDFDSNDFDAVDLWGADGAEGWTADPIIGVGSAATPDTGPDLDNAHGQAETDTEQEIALFTVTNPPRTVSVSTLM
DGRIDHVELSARVAWMSESQLASEILVIADLARQKAQSAQYAFILDRMSQQVDADEHRVALLRKTVGETWGLPSPEEAAA
AEAEVFATRYSDDCPAPDDESDPW
>Mature_184_residues
MDLPGNDFDSNDFDAVDLWGADGAEGWTADPIIGVGSAATPDTGPDLDNAHGQAETDTEQEIALFTVTNPPRTVSVSTLM
DGRIDHVELSARVAWMSESQLASEILVIADLARQKAQSAQYAFILDRMSQQVDADEHRVALLRKTVGETWGLPSPEEAAA
AEAEVFATRYSDDCPAPDDESDPW

Specific function: Required for ESX-1 secretion

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ESPD_MYCTU (O06269)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   G70956
- RefSeq:   NP_218131.1
- RefSeq:   NP_338261.1
- EnsemblBacteria:   EBMYCT00000003664
- EnsemblBacteria:   EBMYCT00000071167
- GeneID:   885777
- GeneID:   922780
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3716
- KEGG:   mtu:Rv3614c
- TIGR:   MT3716
- TubercuList:   Rv3614c
- GeneTree:   EBGT00050000018609
- HOGENOM:   HBG570721
- OMA:   AREANFA
- ProtClustDB:   CLSK792596
- GO:   GO:0009405

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 19835; Mature: 19835

Theoretical pI: Translated: 3.73; Mature: 3.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLPGNDFDSNDFDAVDLWGADGAEGWTADPIIGVGSAATPDTGPDLDNAHGQAETDTEQ
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCC
EIALFTVTNPPRTVSVSTLMDGRIDHVELSARVAWMSESQLASEILVIADLARQKAQSAQ
EEEEEEECCCCCEEEEHHHHCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCH
YAFILDRMSQQVDADEHRVALLRKTVGETWGLPSPEEAAAAEAEVFATRYSDDCPAPDDE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
SDPW
CCCC
>Mature Secondary Structure
MDLPGNDFDSNDFDAVDLWGADGAEGWTADPIIGVGSAATPDTGPDLDNAHGQAETDTEQ
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCC
EIALFTVTNPPRTVSVSTLMDGRIDHVELSARVAWMSESQLASEILVIADLARQKAQSAQ
EEEEEEECCCCCEEEEHHHHCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCH
YAFILDRMSQQVDADEHRVALLRKTVGETWGLPSPEEAAAAEAEVFATRYSDDCPAPDDE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
SDPW
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036