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The map label for this gene is mhpF [C]

Identifier: 148663398

GI number: 148663398

Start: 3982255

End: 3983166

Strand: Reverse

Name: mhpF [C]

Synonym: MRA_3574

Alternate gene names: 148663398

Gene position: 3983166-3982255 (Counterclockwise)

Preceding gene: 148663399

Following gene: 148663397

Centisome position: 90.12

GC content: 66.78

Gene sequence:

>912_bases
ATGCCGTCCAAGGCAAAAGTGGCGATTGTCGGGTCGGGAAATATCAGCACCGATCTGCTGTACAAGCTGCTGCGATCGGA
GTGGCTGGAGCCGCGCTGGATGGTGGGCATCGACCCGGAGAGCGATGGCCTGGCGCGCGCGGCCAAGCTGGGTTTGGAGA
CCACCCACGAGGGGGTGGACTGGCTGCTGGCGCAGCCCGATAAACCCGACCTGGTGTTCGAGGCAACCAGTGCCTACGTG
CACCGGGACGCGGCGCCCAAGTACGCCGAGGCCGGGATCCGGGCCATCGACCTGACGCCGGCGGCGGTGGGTCCGGCGGT
GATCCCGCCGGCGAACCTGCGCGAGCACCTGGACGCGCCGAACGTCAACATGATCACCTGCGGGGGACAGGCGACCATTC
CGATCGTGTACGCGGTGTCTCGGATCGTGGAGGTGCCCTACGCCGAGATCGTGGCGTCGGTGGCTTCCGTTTCAGCGGGA
CCGGGCACGCGCGCCAACATCGACGAGTTCACCAAGACCACCGCCCGTGGGGTCCAGACCATCGGCGGGGCCGCCCGCGG
CAAGGCGATCATCATCTTGAATCCCGCCGACCCGCCGATGATCATGCGCGACACCATCTTTTGCGCCATCCCCACCGACG
CCGACCGCGAAGCGATCGCCGCCTCCATCCACGACGTCGTCAAAGAGGTGCAGACCTACGTGCCTGGATACCGGCTGCTC
AACGAACCGCAGTTCGACGAGCCGTCGATCAACTCGGGCGGGCAGGCGCTGGTCACCACGTTCGTCGAGGTTGAGGGCGC
CGGGGATTACCTGCCGCCCTATGCGGGCAACCTGGACATCATGACCGCGGCGGCCACCAAGGTGGGCGAGGAGATCGCCA
AGGAGACGCTGGTTGTAGGAGGAGCGCGATGA

Upstream 100 bases:

>100_bases
TCATGCACGTTCGCGGTCGAGGCGCGGGCCGGCGACGAGTTTGTCGCCGACTTCACCGGGCTGGGTTTGGTCCGGTTGTC
GTTCGAATAAGGGGAGCAAC

Downstream 100 bases:

>100_bases
CCGATATGTGGGACGTCCGCATCACGGACACCTCGCTGCGGGATGGGTCGCACCACAAACGCCACCAATTCACCAAGGAC
GAGGTCGGTGCCATCGTGGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] 2 [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPSKAKVAIVGSGNISTDLLYKLLRSEWLEPRWMVGIDPESDGLARAAKLGLETTHEGVDWLLAQPDKPDLVFEATSAYV
HRDAAPKYAEAGIRAIDLTPAAVGPAVIPPANLREHLDAPNVNMITCGGQATIPIVYAVSRIVEVPYAEIVASVASVSAG
PGTRANIDEFTKTTARGVQTIGGAARGKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPGYRLL
NEPQFDEPSINSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLVVGGAR

Sequences:

>Translated_303_residues
MPSKAKVAIVGSGNISTDLLYKLLRSEWLEPRWMVGIDPESDGLARAAKLGLETTHEGVDWLLAQPDKPDLVFEATSAYV
HRDAAPKYAEAGIRAIDLTPAAVGPAVIPPANLREHLDAPNVNMITCGGQATIPIVYAVSRIVEVPYAEIVASVASVSAG
PGTRANIDEFTKTTARGVQTIGGAARGKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPGYRLL
NEPQFDEPSINSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLVVGGAR
>Mature_302_residues
PSKAKVAIVGSGNISTDLLYKLLRSEWLEPRWMVGIDPESDGLARAAKLGLETTHEGVDWLLAQPDKPDLVFEATSAYVH
RDAAPKYAEAGIRAIDLTPAAVGPAVIPPANLREHLDAPNVNMITCGGQATIPIVYAVSRIVEVPYAEIVASVASVSAGP
GTRANIDEFTKTTARGVQTIGGAARGKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPGYRLLN
EPQFDEPSINSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLVVGGAR

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds [H]

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786547, Length=306, Percent_Identity=54.9019607843137, Blast_Score=318, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.10 [H]

Molecular weight: Translated: 32009; Mature: 31878

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSKAKVAIVGSGNISTDLLYKLLRSEWLEPRWMVGIDPESDGLARAAKLGLETTHEGVD
CCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCC
WLLAQPDKPDLVFEATSAYVHRDAAPKYAEAGIRAIDLTPAAVGPAVIPPANLREHLDAP
EEEECCCCCCEEEEEHHHHHCCCCCCHHHHCCCEEEECCCHHCCCCCCCCCHHHHHCCCC
NVNMITCGGQATIPIVYAVSRIVEVPYAEIVASVASVSAGPGTRANIDEFTKTTARGVQT
CCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
IGGAARGKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPGYRLL
HCCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHC
NEPQFDEPSINSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLVVG
CCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHEEC
GAR
CCC
>Mature Secondary Structure 
PSKAKVAIVGSGNISTDLLYKLLRSEWLEPRWMVGIDPESDGLARAAKLGLETTHEGVD
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCC
WLLAQPDKPDLVFEATSAYVHRDAAPKYAEAGIRAIDLTPAAVGPAVIPPANLREHLDAP
EEEECCCCCCEEEEEHHHHHCCCCCCHHHHCCCEEEECCCHHCCCCCCCCCHHHHHCCCC
NVNMITCGGQATIPIVYAVSRIVEVPYAEIVASVASVSAGPGTRANIDEFTKTTARGVQT
CCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
IGGAARGKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPGYRLL
HCCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHC
NEPQFDEPSINSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLVVG
CCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHEEC
GAR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA