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The map label for this gene is ppe22

Identifier: 148661502

GI number: 148661502

Start: 1933015

End: 1934172

Strand: Reverse

Name: ppe22

Synonym: MRA_1714

Alternate gene names: 148661502

Gene position: 1934172-1933015 (Counterclockwise)

Preceding gene: 148661503

Following gene: 148661501

Centisome position: 43.76

GC content: 67.62

Gene sequence:

>1158_bases
ATGGATTTTGGGGCGTTGCCACCGGAGGTGAACTCCGGGCGCATGTATTGCGGCCCGGGCTCGGCACCGATGGTTGCCGC
AGCGTCCGCGTGGAACGGGCTGGCCGCCGAGCTCAGTGTGGCCGCCGTCGGCTACGAGCGGGTGATCACGACGCTGCAAA
CCGAAGAATGGCTGGGTCCGGCGTCGACGTTGATGGTCGAAGCGGTCGCCCCGTATGTGGCGTGGATGCGAGCCACCGCC
ATCCAAGCTGAGCAGGCAGCCAGTCAGGCGCGTGCGGCGGCGGCCGCTTACGAAACCGCGTTTGCCGCCATTGTGCCCCC
GCCGCTGATCGCGGCCAATCGCGCGCGGCTCACGTCGCTGGTCACGCATAACGTGTTCGGTCAAAACACCGCATCAATCG
CGGCCACCGAAGCTCAATACGCTGAAATGTGGGCCCAAGACGCCATGGCCATGTACGGTTACGCGGGCTCCTCGGCGACC
GCGACCAAAGTGACGCCGTTTGCCCCGCCGCCGAACACCACCAGCCCATCCGCCGCGGCGACGCAGTTGTCCGCAGTCGC
CAAAGCCGCCGGCACCTCAGCCGGCGCGGCGCAGAGCGCAATAGCGGAGCTGATCGCCCACTTGCCCAACACGCTGCTGG
GCCTCACCTCGCCCCTGTCGTCCGCGTTGACCGCCGCCGCGACCCCGGGGTGGCTGGAATGGTTCATCAACTGGTATCTG
CCGATATCACAGCTGTTTTACAACACCGTGGGTTTGCCATATTTCGCCATTGGTATTGGCAACAGCCTTATTACATCGTG
GCGGGCGCTGGGATGGATCGGTCCCGAGGCCGCCGAAGCTGCCGCCGCGGCGCCGGCGGCCGTCGGCGCCGCGGTTGGCG
GTACCGGACCCGTATCCGCGGGTCTAGGCAACGCGGCCACCATCGGCAAGTTATCGCTGCCGCCCAACTGGGCAGGGGCC
AGTCCGAGCCTAGCCCCGACCGTGGGTTCGGCCTCCGCACCCCTGGTCAGCGATATCGTCGAGCAACCGGAGGCCGGTGC
GGCGGGAAACCTGTTGGGCGGCATGCCGCTAGCCGGTTCGGGCACCGGTACGGGGGGTGCGGGTCCCCGCTACGGGTTCC
GGGTTACGGTGATGTCCCGGCCGCCGTTTGCCGGATAA

Upstream 100 bases:

>100_bases
TATGGGACGCCGATATGGAAGACGACTCACCGTGATGGCTGACCGGCCGAACGTCGGATAGCCCACCGAAAACCCGTGAC
GAGGTAAGGAGTTCATAGCG

Downstream 100 bases:

>100_bases
CGCGAGGCCTTCCCTACCCCAGAACTCGAGGACGCCATATATGCCGGACGATATCGCGGCTGCCGACCCGACAGACACCC
AGCCGCACCTGCGTCGGGAC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGPASTLMVEAVAPYVAWMRATA
IQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSLVTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSAT
ATKVTPFAPPPNTTSPSAAATQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWLEWFINWYL
PISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSLPPNWAGA
SPSLAPTVGSASAPLVSDIVEQPEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG

Sequences:

>Translated_385_residues
MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGPASTLMVEAVAPYVAWMRATA
IQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSLVTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSAT
ATKVTPFAPPPNTTSPSAAATQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWLEWFINWYL
PISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSLPPNWAGA
SPSLAPTVGSASAPLVSDIVEQPEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG
>Mature_385_residues
MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGPASTLMVEAVAPYVAWMRATA
IQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSLVTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSAT
ATKVTPFAPPPNTTSPSAAATQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWLEWFINWYL
PISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSLPPNWAGA
SPSLAPTVGSASAPLVSDIVEQPEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE22_MYCTU (Q79FL6)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   H70503
- RefSeq:   NP_336200.1
- RefSeq:   YP_177827.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q79FL6
- SMR:   Q79FL6
- EnsemblBacteria:   EBMYCT00000001327
- EnsemblBacteria:   EBMYCT00000072685
- GeneID:   885068
- GeneID:   923961
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1745
- KEGG:   mtu:Rv1705c
- TIGR:   MT1745
- TubercuList:   Rv1705c
- GeneTree:   EBGT00050000014887
- HOGENOM:   HBG572308
- OMA:   LITSERA
- ProtClustDB:   CLSK799827
- InterPro:   IPR022171
- InterPro:   IPR000030

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE

EC number: NA

Molecular weight: Translated: 38444; Mature: 38444

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP
CCCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWLEWFINWYL
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
PISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAVGAAVGGTGPVSA
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHCCCCCCCCC
GLGNAATIGKLSLPPNWAGASPSLAPTVGSASAPLVSDIVEQPEAGAAGNLLGGMPLAGS
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
GTGTGGAGPRYGFRVTVMSRPPFAG
CCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP
CCCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWLEWFINWYL
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
PISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAVGAAVGGTGPVSA
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHCCCCCCCCC
GLGNAATIGKLSLPPNWAGASPSLAPTVGSASAPLVSDIVEQPEAGAAGNLLGGMPLAGS
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
GTGTGGAGPRYGFRVTVMSRPPFAG
CCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036