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The map label for this gene is ppe23

Identifier: 148661503

GI number: 148661503

Start: 1934212

End: 1935396

Strand: Reverse

Name: ppe23

Synonym: MRA_1715

Alternate gene names: 148661503

Gene position: 1935396-1934212 (Counterclockwise)

Preceding gene: 148661504

Following gene: 148661502

Centisome position: 43.79

GC content: 67.93

Gene sequence:

>1185_bases
ATGACCCTCGATGTCCCGGTCAACCAGGGGCATGTCCCCCCGGGCAGCGTCGCCTGCTGCCTTGTTGGGGTCACCGCCGT
TGCTGACGGCATCGCCGGGCATTCCCTGTCCAACTTTGGGGCGTTACCTCCCGAGATCAATTCGGGTCGTATGTATAGCG
GTCCGGGATCCGGGCCACTGATGGCTGCCGCGGCGGCCTGGGACGGGCTGGCCGCAGAGTTGTCGTCGGCAGCGACTGGC
TACGGTGCGGCGATCTCGGAGCTGACAAACATGCGGTGGTGGTCGGGGCCGGCATCGGATTCGATGGTGGCCGCCGTCCT
GCCCTTTGTCGGCTGGCTGAGTACCACCGCGACGCTAGCCGAACAGGCCGCGATGCAGGCTAGGGCGGCCGCAGCGGCCT
TTGAAGCCGCCTTCGCCATGACGGTGCCCCCGCCGGCGATCGCGGCCAACCGGACCTTGTTGATGACGCTCGTCGATACC
AACTGGTTCGGGCAAAACACGCCGGCGATCGCCACCACCGAGTCCCAATACGCCGAGATGTGGGCCCAAGACGCCGCCGC
GATGTACGGCTATGCCAGCGCCGCGGCACCCGCCACGGTTTTGACTCCGTTCGCACCACCGCCGCAAACCACCAACGCGA
CCGGCCTCGTCGGCCACGCAACAGCGGTGGCCGCGCTGCGGGGGCAGCACAGCTGGGCCGCGGCGATTCCATGGAGCGAC
ATACAGAAATACTGGATGATGTTCCTGGGCGCCCTCGCCACTGCCGAAGGGTTCATTTACGACAGCGGTGGGTTAACGCT
GAATGCTCTGCAGTTCGTCGGCGGGATGTTGTGGAGCACCGCATTGGCAGAAGCCGGTGCGGCCGAGGCAGCGGCCGGCG
CGGGTGGAGCCGCTGGATGGTCGGCGTGGTCGCAGCTGGGAGCTGGACCGGTGGCGGCGAGCGCGACTCTGGCCGCCAAG
ATCGGACCGATGTCGGTGCCGCCGGGCTGGTCCGCACCGCCCGCCACGCCCCAGGCGCAAACCGTCGCGCGATCGATTCC
CGGTATTCGCAGCGCCGCCGAGGCGGCTGAAACATCGGTCCTACTCCGGGGGGCACCGACTCCGGGCAGGAGTCGCGCCG
CCCATATGGGACGCCGATATGGAAGACGACTCACCGTGATGGCTGACCGGCCGAACGTCGGATAG

Upstream 100 bases:

>100_bases
CTCTTATGGAGATTAACGTGCTAGGTCACTGTTGCCCTAGTCATAGCTATCGTATCGACGACGGTGTCGAGCCAGCCCAC
CCATAACGAGGCGGTTTTCG

Downstream 100 bases:

>100_bases
CCCACCGAAAACCCGTGACGAGGTAAGGAGTTCATAGCGATGGATTTTGGGGCGTTGCCACCGGAGGTGAACTCCGGGCG
CATGTATTGCGGCCCGGGCT

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MTLDVPVNQGHVPPGSVACCLVGVTAVADGIAGHSLSNFGALPPEINSGRMYSGPGSGPLMAAAAAWDGLAAELSSAATG
YGAAISELTNMRWWSGPASDSMVAAVLPFVGWLSTTATLAEQAAMQARAAAAAFEAAFAMTVPPPAIAANRTLLMTLVDT
NWFGQNTPAIATTESQYAEMWAQDAAAMYGYASAAAPATVLTPFAPPPQTTNATGLVGHATAVAALRGQHSWAAAIPWSD
IQKYWMMFLGALATAEGFIYDSGGLTLNALQFVGGMLWSTALAEAGAAEAAAGAGGAAGWSAWSQLGAGPVAASATLAAK
IGPMSVPPGWSAPPATPQAQTVARSIPGIRSAAEAAETSVLLRGAPTPGRSRAAHMGRRYGRRLTVMADRPNVG

Sequences:

>Translated_394_residues
MTLDVPVNQGHVPPGSVACCLVGVTAVADGIAGHSLSNFGALPPEINSGRMYSGPGSGPLMAAAAAWDGLAAELSSAATG
YGAAISELTNMRWWSGPASDSMVAAVLPFVGWLSTTATLAEQAAMQARAAAAAFEAAFAMTVPPPAIAANRTLLMTLVDT
NWFGQNTPAIATTESQYAEMWAQDAAAMYGYASAAAPATVLTPFAPPPQTTNATGLVGHATAVAALRGQHSWAAAIPWSD
IQKYWMMFLGALATAEGFIYDSGGLTLNALQFVGGMLWSTALAEAGAAEAAAGAGGAAGWSAWSQLGAGPVAASATLAAK
IGPMSVPPGWSAPPATPQAQTVARSIPGIRSAAEAAETSVLLRGAPTPGRSRAAHMGRRYGRRLTVMADRPNVG
>Mature_393_residues
TLDVPVNQGHVPPGSVACCLVGVTAVADGIAGHSLSNFGALPPEINSGRMYSGPGSGPLMAAAAAWDGLAAELSSAATGY
GAAISELTNMRWWSGPASDSMVAAVLPFVGWLSTTATLAEQAAMQARAAAAAFEAAFAMTVPPPAIAANRTLLMTLVDTN
WFGQNTPAIATTESQYAEMWAQDAAAMYGYASAAAPATVLTPFAPPPQTTNATGLVGHATAVAALRGQHSWAAAIPWSDI
QKYWMMFLGALATAEGFIYDSGGLTLNALQFVGGMLWSTALAEAGAAEAAAGAGGAAGWSAWSQLGAGPVAASATLAAKI
GPMSVPPGWSAPPATPQAQTVARSIPGIRSAAEAAETSVLLRGAPTPGRSRAAHMGRRYGRRLTVMADRPNVG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE23_MYCTU (Q7D842)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   A70504
- RefSeq:   NP_336201.1
- RefSeq:   YP_177828.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q7D842
- SMR:   Q7D842
- EnsemblBacteria:   EBMYCT00000003365
- EnsemblBacteria:   EBMYCT00000069715
- GeneID:   885070
- GeneID:   923960
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1746
- KEGG:   mtu:Rv1706c
- TIGR:   MT1746
- TubercuList:   Rv1706c
- GeneTree:   EBGT00050000014888
- HOGENOM:   HBG572308
- OMA:   WIELMSS
- ProtClustDB:   CLSK799828
- InterPro:   IPR022171
- InterPro:   IPR000030

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE

EC number: NA

Molecular weight: Translated: 39778; Mature: 39647

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDVPVNQGHVPPGSVACCLVGVTAVADGIAGHSLSNFGALPPEINSGRMYSGPGSGPL
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEECCCCCCCH
MAAAAAWDGLAAELSSAATGYGAAISELTNMRWWSGPASDSMVAAVLPFVGWLSTTATLA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EQAAMQARAAAAAFEAAFAMTVPPPAIAANRTLLMTLVDTNWFGQNTPAIATTESQYAEM
HHHHHHHHHHHHHHHHHEEEECCCCCHHCCCEEEEEEEECCCCCCCCCCEEECHHHHHHH
WAQDAAAMYGYASAAAPATVLTPFAPPPQTTNATGLVGHATAVAALRGQHSWAAAIPWSD
HHHHHHHHHCCHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCHHH
IQKYWMMFLGALATAEGFIYDSGGLTLNALQFVGGMLWSTALAEAGAAEAAAGAGGAAGW
HHHHHHHHHHHHHHHCCEEEECCCCEEHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHH
SAWSQLGAGPVAASATLAAKIGPMSVPPGWSAPPATPQAQTVARSIPGIRSAAEAAETSV
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHEE
LLRGAPTPGRSRAAHMGRRYGRRLTVMADRPNVG
EEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCC
>Mature Secondary Structure 
TLDVPVNQGHVPPGSVACCLVGVTAVADGIAGHSLSNFGALPPEINSGRMYSGPGSGPL
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEECCCCCCCH
MAAAAAWDGLAAELSSAATGYGAAISELTNMRWWSGPASDSMVAAVLPFVGWLSTTATLA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EQAAMQARAAAAAFEAAFAMTVPPPAIAANRTLLMTLVDTNWFGQNTPAIATTESQYAEM
HHHHHHHHHHHHHHHHHEEEECCCCCHHCCCEEEEEEEECCCCCCCCCCEEECHHHHHHH
WAQDAAAMYGYASAAAPATVLTPFAPPPQTTNATGLVGHATAVAALRGQHSWAAAIPWSD
HHHHHHHHHCCHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCHHH
IQKYWMMFLGALATAEGFIYDSGGLTLNALQFVGGMLWSTALAEAGAAEAAAGAGGAAGW
HHHHHHHHHHHHHHHCCEEEECCCCEEHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHH
SAWSQLGAGPVAASATLAAKIGPMSVPPGWSAPPATPQAQTVARSIPGIRSAAEAAETSV
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHEE
LLRGAPTPGRSRAAHMGRRYGRRLTVMADRPNVG
EEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036