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The map label for this gene is cidB [H]

Identifier: 148653667

GI number: 148653667

Start: 2326547

End: 2327251

Strand: Direct

Name: cidB [H]

Synonym: PsycPRwf_1870

Alternate gene names: 148653667

Gene position: 2326547-2327251 (Clockwise)

Preceding gene: 148653666

Following gene: 148653668

Centisome position: 78.1

GC content: 46.38

Gene sequence:

>705_bases
ATGACTTTACTCAATCAAATGCCTGAAGGCACCACGTTGTTGACTGTACTTGCCGCTTTTGTTCTCACTTTAGTGGCACA
TGTGATGGCACGTATCTTATCCAAGCGCATCTCAGGGCTGCCCATGGTCATCACAGCCTTGGTACTGGTACTGGTATTTT
TATATCTATTTAGTTGGGATTACGATCATTATTATGCTGTGGCCAAGCCGGTTTTTGATCATTTATTGGGCTATGTGACC
GTACTACTCGCCATTCCTTTAGCTACGATGAATTTTTCTGGCTTACCAGTAAAAAAACTTAGCATCATAGTGGTGATCGC
AAGCTTGGTAGGTGCCCTACTGCCTATGTCTATGGCTTATGGCTTCTCACTAAGTCACGATACTATTTTAGCCTTCGCAA
CGCGTTCGGTGACCACCCCTATTGGGCTAAGTGTGGCCGAAATTATTAAAGCACCTTTGGCCTTAGCCAACCTAATCATC
ATCGTCTCTGGTTTGCTTGGTGGCGCTGTGGCTCGTGTGTTGTTCAAAAACGTACAAGACGATAGAGCCAAAGGCTTGGC
ACTGGGTTTGGCAGCTCATGCCTTTGGTACGGTAGAGGCGTGGCAAATTAGCCATACTGCTGGGCGCTATGCCGCCTTTG
GACTGGCGGTAAATGGCTTAGTCACTGCGGTATGGGTGCCAATATTTTTAGCCGCTATATTATAA

Upstream 100 bases:

>100_bases
TGGCACGACTCGCCAACTATTGGTTAAGCCGTCAGCCTGAGGGCTCTAATGAGAGCGATACCAACACCTCTTCTACTCAA
TCAAAATAAGGCCTCAAGCT

Downstream 100 bases:

>100_bases
AAACGCTCAAAAAGTGAGGGTTAACGCACCCTAATATCAGGCCAAGTTATATAGCAGAAGATATTTAGTAACAATATTAC
TTATTCTTTCTAAACTGCTG

Product: LrgB family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTLLNQMPEGTTLLTVLAAFVLTLVAHVMARILSKRISGLPMVITALVLVLVFLYLFSWDYDHYYAVAKPVFDHLLGYVT
VLLAIPLATMNFSGLPVKKLSIIVVIASLVGALLPMSMAYGFSLSHDTILAFATRSVTTPIGLSVAEIIKAPLALANLII
IVSGLLGGAVARVLFKNVQDDRAKGLALGLAAHAFGTVEAWQISHTAGRYAAFGLAVNGLVTAVWVPIFLAAIL

Sequences:

>Translated_234_residues
MTLLNQMPEGTTLLTVLAAFVLTLVAHVMARILSKRISGLPMVITALVLVLVFLYLFSWDYDHYYAVAKPVFDHLLGYVT
VLLAIPLATMNFSGLPVKKLSIIVVIASLVGALLPMSMAYGFSLSHDTILAFATRSVTTPIGLSVAEIIKAPLALANLII
IVSGLLGGAVARVLFKNVQDDRAKGLALGLAAHAFGTVEAWQISHTAGRYAAFGLAVNGLVTAVWVPIFLAAIL
>Mature_233_residues
TLLNQMPEGTTLLTVLAAFVLTLVAHVMARILSKRISGLPMVITALVLVLVFLYLFSWDYDHYYAVAKPVFDHLLGYVTV
LLAIPLATMNFSGLPVKKLSIIVVIASLVGALLPMSMAYGFSLSHDTILAFATRSVTTPIGLSVAEIIKAPLALANLIII
VSGLLGGAVARVLFKNVQDDRAKGLALGLAAHAFGTVEAWQISHTAGRYAAFGLAVNGLVTAVWVPIFLAAIL

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.

COG id: COG1346

COG function: function code M; Putative effector of murein hydrolase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidB/LrgB family. CidB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788464, Length=220, Percent_Identity=29.0909090909091, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007300 [H]

Pfam domain/function: PF04172 LrgB [H]

EC number: NA

Molecular weight: Translated: 24854; Mature: 24723

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLNQMPEGTTLLTVLAAFVLTLVAHVMARILSKRISGLPMVITALVLVLVFLYLFSWD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
YDHYYAVAKPVFDHLLGYVTVLLAIPLATMNFSGLPVKKLSIIVVIASLVGALLPMSMAY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GFSLSHDTILAFATRSVTTPIGLSVAEIIKAPLALANLIIIVSGLLGGAVARVLFKNVQD
CCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRAKGLALGLAAHAFGTVEAWQISHTAGRYAAFGLAVNGLVTAVWVPIFLAAIL
HHHHHHHHHHHHHHHCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TLLNQMPEGTTLLTVLAAFVLTLVAHVMARILSKRISGLPMVITALVLVLVFLYLFSWD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
YDHYYAVAKPVFDHLLGYVTVLLAIPLATMNFSGLPVKKLSIIVVIASLVGALLPMSMAY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GFSLSHDTILAFATRSVTTPIGLSVAEIIKAPLALANLIIIVSGLLGGAVARVLFKNVQD
CCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRAKGLALGLAAHAFGTVEAWQISHTAGRYAAFGLAVNGLVTAVWVPIFLAAIL
HHHHHHHHHHHHHHHCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA