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The map label for this gene is dppC [H]

Identifier: 148653326

GI number: 148653326

Start: 1868850

End: 1869761

Strand: Direct

Name: dppC [H]

Synonym: PsycPRwf_1528

Alternate gene names: 148653326

Gene position: 1868850-1869761 (Clockwise)

Preceding gene: 148653325

Following gene: 148653327

Centisome position: 62.73

GC content: 49.78

Gene sequence:

>912_bases
ATGAAGACTAACGTACTTCCCGAAGATATCGAGCTTGCCGCAGCGCCCCCCTCCTCATGGCGGCTGTTTGTCGCAACGTT
TTGTCGCAACCGAGGCGCCGTGCTTGGCCTACTGGTATTAGTGCTCATGGTCATAGTGGCACTGCTTGCGCCCAGCATTG
CACCACATGACCCTTACGAGCTATTTACAGGAAAAGAGCAGCTCCCACCGTCGTTTATGAGTGGCGGCGATGCCATGTTC
TTTTTAGGCACCGATGATGCCGGCCGTGATACCTTGTCTCGGGTGATGTATGGCGCTCGCTATTCATTATTTATCGGCCT
CAGTGCCACAACTTTGGCCATGATTACTGGCATCAGCCTAGGCCTTAGCGCCGCCTTTTGGCCCAAAGTTTGGGGTAAGG
CTGTGATGCTTGTTAACGATATTTTGATGTCGTATCCAAGCTTATTATTGGCTATTATCATTGCGGCCATTTTAGGTCCA
AACATGACCAATACCATCATCACCATTGCCTTGGTGTGTACCCCGCCTTTTATTCGTTTGACCCGAGCCACTGCCATGGT
CGAATTGCAACGAGAATACTTCACAGCCTCTAAGGTGATGGGCGCTGGCGTACTTAGGCTATTATTTATCACGATTTTGC
CTAATTGTATGGCGCCGCTTATTGTGCAGGCCACCATGATATTCTCCTCAGCCATTTTAGAAGCTGGCGCAATTGGATTT
TTGGGCTTTGGCGTACAGCCGCCAGACGCAGAATGGGGTGCAATGCTGGGTACCGCTCGTCAATACATTCAAAGCAATGT
GTGGCTTGCCATTTGGCCCGGTTTGGCTATTTTCTTAGCCGCTTTATCTATTAACTTAACCGGAGATGGGCTACGTGATG
CTCTTGATCCTAAACTAAAGCAGGTGAGCTAA

Upstream 100 bases:

>100_bases
ATAGGCTATCTGTTATGCAGCCATTATTTATGAGCTTATTCGTCCTATATAACCAAAAAATTTTATTATCAAATCGCCTT
AGAAAAATAGGAAAATCCAA

Downstream 100 bases:

>100_bases
TGACAACTTTAAATTCTAATCCTGCCGCCTCAACGCTTAGCTCTGATCACCTTGTGAACACCCAAAATGAGGCCACTGGC
CAACACGCTGCACCGCTGCT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKTNVLPEDIELAAAPPSSWRLFVATFCRNRGAVLGLLVLVLMVIVALLAPSIAPHDPYELFTGKEQLPPSFMSGGDAMF
FLGTDDAGRDTLSRVMYGARYSLFIGLSATTLAMITGISLGLSAAFWPKVWGKAVMLVNDILMSYPSLLLAIIIAAILGP
NMTNTIITIALVCTPPFIRLTRATAMVELQREYFTASKVMGAGVLRLLFITILPNCMAPLIVQATMIFSSAILEAGAIGF
LGFGVQPPDAEWGAMLGTARQYIQSNVWLAIWPGLAIFLAALSINLTGDGLRDALDPKLKQVS

Sequences:

>Translated_303_residues
MKTNVLPEDIELAAAPPSSWRLFVATFCRNRGAVLGLLVLVLMVIVALLAPSIAPHDPYELFTGKEQLPPSFMSGGDAMF
FLGTDDAGRDTLSRVMYGARYSLFIGLSATTLAMITGISLGLSAAFWPKVWGKAVMLVNDILMSYPSLLLAIIIAAILGP
NMTNTIITIALVCTPPFIRLTRATAMVELQREYFTASKVMGAGVLRLLFITILPNCMAPLIVQATMIFSSAILEAGAIGF
LGFGVQPPDAEWGAMLGTARQYIQSNVWLAIWPGLAIFLAALSINLTGDGLRDALDPKLKQVS
>Mature_303_residues
MKTNVLPEDIELAAAPPSSWRLFVATFCRNRGAVLGLLVLVLMVIVALLAPSIAPHDPYELFTGKEQLPPSFMSGGDAMF
FLGTDDAGRDTLSRVMYGARYSLFIGLSATTLAMITGISLGLSAAFWPKVWGKAVMLVNDILMSYPSLLLAIIIAAILGP
NMTNTIITIALVCTPPFIRLTRATAMVELQREYFTASKVMGAGVLRLLFITILPNCMAPLIVQATMIFSSAILEAGAIGF
LGFGVQPPDAEWGAMLGTARQYIQSNVWLAIWPGLAIFLAALSINLTGDGLRDALDPKLKQVS

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=299, Percent_Identity=48.1605351170569, Blast_Score=243, Evalue=8e-66,
Organism=Escherichia coli, GI1787054, Length=281, Percent_Identity=37.7224199288256, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1787760, Length=261, Percent_Identity=40.6130268199234, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1787549, Length=280, Percent_Identity=36.0714285714286, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789889, Length=246, Percent_Identity=38.2113821138211, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1787498, Length=288, Percent_Identity=29.8611111111111, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1788505, Length=225, Percent_Identity=27.5555555555556, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32510; Mature: 32510

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNVLPEDIELAAAPPSSWRLFVATFCRNRGAVLGLLVLVLMVIVALLAPSIAPHDPYE
CCCCCCCCCCCEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LFTGKEQLPPSFMSGGDAMFFLGTDDAGRDTLSRVMYGARYSLFIGLSATTLAMITGISL
HHCCCHHCCCHHHCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
GLSAAFWPKVWGKAVMLVNDILMSYPSLLLAIIIAAILGPNMTNTIITIALVCTPPFIRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHH
TRATAMVELQREYFTASKVMGAGVLRLLFITILPNCMAPLIVQATMIFSSAILEAGAIGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LGFGVQPPDAEWGAMLGTARQYIQSNVWLAIWPGLAIFLAALSINLTGDGLRDALDPKLK
EECCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCHHHHCCCHHH
QVS
CCC
>Mature Secondary Structure
MKTNVLPEDIELAAAPPSSWRLFVATFCRNRGAVLGLLVLVLMVIVALLAPSIAPHDPYE
CCCCCCCCCCCEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LFTGKEQLPPSFMSGGDAMFFLGTDDAGRDTLSRVMYGARYSLFIGLSATTLAMITGISL
HHCCCHHCCCHHHCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
GLSAAFWPKVWGKAVMLVNDILMSYPSLLLAIIIAAILGPNMTNTIITIALVCTPPFIRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHH
TRATAMVELQREYFTASKVMGAGVLRLLFITILPNCMAPLIVQATMIFSSAILEAGAIGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LGFGVQPPDAEWGAMLGTARQYIQSNVWLAIWPGLAIFLAALSINLTGDGLRDALDPKLK
EECCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCHHHHCCCHHH
QVS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]