Click here to switch to the map view.

The map label for this gene is purN [H]

Identifier: 148653243

GI number: 148653243

Start: 1765612

End: 1766310

Strand: Direct

Name: purN [H]

Synonym: PsycPRwf_1441

Alternate gene names: 148653243

Gene position: 1765612-1766310 (Clockwise)

Preceding gene: 148653242

Following gene: 148653250

Centisome position: 59.27

GC content: 49.07

Gene sequence:

>699_bases
ATGTCGGTATCTACTGTATCTACCAACCCCTTAAAAGTCGCCGTCTTAGTCTCAGGCAGTGGCAGCAATCTGCAAGTCCT
GATTGATGCCATGCAGGCCGGTAGTTTGCCCATCGAGATTGTCGGTGTCATTAGTAATGTCAAAGACGCTTATGCGGTGA
CCCGTGCACAGCAAGCGGGGATCGCCACAGCGGTATTCTCACACATTACTGAAGGTGAGAATGCCGGCAAGCGCATGGGT
ATTAAAACTTTTGAGCGTCATGCCAGCGCCCAGCTTAACGATTGGCAGCCAGACTTAGTGGTACTGGCAGGCTTTATGCG
TGTGTTAAGCGATGACTTCATTAGTAGCTCGCCTGCTCCTATGATTAATCTACACCCCTCTTTACTACCTAAGTATAAGG
GTTTAGATACCCATCAGCGGGTCTTACAATCAAGCGATGTCCATCATGGATGCAGCGTTCATGTGGTAACGGCTGAATTG
GATGCGGGTCAAGTATTGACTCAAGCCATGCTGGCTGTGGATCACAGTGAGTCAGCTCAAGGGCTACAAGCCCGCGTACA
AAAGCTTGAGCATCAAGTCTTGCCTTGGACCATATTACTGATTGCCCATGGGGTGTTAGACATTAAGGCCATCAATGAGC
AAACAGCAGCAACCGCTTATTTGCCTGAACTGCCCTTAAAGCTTTGGCTAGACAGCTAA

Upstream 100 bases:

>100_bases
GCCAATCAAGCCGTTGATATTTTAAATGACGCTGGCGAGAAAGCCTTTATCTTTGGTGACATCATCGAGCGTACAGATGA
TGCTGTGGTTTACGCCTAAT

Downstream 100 bases:

>100_bases
CTTGCCGCTTCAATATAACAACAAAGCCCAAATCTATAGATTTGGGCTTTGTTGTGTCTGCCTATATAAAACTTGGTATG
TTAGAGCAGTGCGTTTAAAG

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSVSTVSTNPLKVAVLVSGSGSNLQVLIDAMQAGSLPIEIVGVISNVKDAYAVTRAQQAGIATAVFSHITEGENAGKRMG
IKTFERHASAQLNDWQPDLVVLAGFMRVLSDDFISSSPAPMINLHPSLLPKYKGLDTHQRVLQSSDVHHGCSVHVVTAEL
DAGQVLTQAMLAVDHSESAQGLQARVQKLEHQVLPWTILLIAHGVLDIKAINEQTAATAYLPELPLKLWLDS

Sequences:

>Translated_232_residues
MSVSTVSTNPLKVAVLVSGSGSNLQVLIDAMQAGSLPIEIVGVISNVKDAYAVTRAQQAGIATAVFSHITEGENAGKRMG
IKTFERHASAQLNDWQPDLVVLAGFMRVLSDDFISSSPAPMINLHPSLLPKYKGLDTHQRVLQSSDVHHGCSVHVVTAEL
DAGQVLTQAMLAVDHSESAQGLQARVQKLEHQVLPWTILLIAHGVLDIKAINEQTAATAYLPELPLKLWLDS
>Mature_231_residues
SVSTVSTNPLKVAVLVSGSGSNLQVLIDAMQAGSLPIEIVGVISNVKDAYAVTRAQQAGIATAVFSHITEGENAGKRMGI
KTFERHASAQLNDWQPDLVVLAGFMRVLSDDFISSSPAPMINLHPSLLPKYKGLDTHQRVLQSSDVHHGCSVHVVTAELD
AGQVLTQAMLAVDHSESAQGLQARVQKLEHQVLPWTILLIAHGVLDIKAINEQTAATAYLPELPLKLWLDS

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=197, Percent_Identity=36.0406091370558, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI209869995, Length=197, Percent_Identity=36.0406091370558, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI209869993, Length=197, Percent_Identity=36.0406091370558, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI1788846, Length=198, Percent_Identity=42.4242424242424, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1787483, Length=185, Percent_Identity=27.5675675675676, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17567511, Length=203, Percent_Identity=32.0197044334975, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320616, Length=196, Percent_Identity=33.6734693877551, Blast_Score=93, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24582400, Length=195, Percent_Identity=36.9230769230769, Blast_Score=127, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 24879; Mature: 24748

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSTVSTNPLKVAVLVSGSGSNLQVLIDAMQAGSLPIEIVGVISNVKDAYAVTRAQQAG
CCCCCCCCCCEEEEEEEECCCCCCEEEEEHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHH
IATAVFSHITEGENAGKRMGIKTFERHASAQLNDWQPDLVVLAGFMRVLSDDFISSSPAP
HHHHHHHHHHCCCCCCHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
MINLHPSLLPKYKGLDTHQRVLQSSDVHHGCSVHVVTAELDAGQVLTQAMLAVDHSESAQ
EEECCHHHCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCHH
GLQARVQKLEHQVLPWTILLIAHGVLDIKAINEQTAATAYLPELPLKLWLDS
HHHHHHHHHHHHHCCHHHHHHHHCHHEEEECCCHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure 
SVSTVSTNPLKVAVLVSGSGSNLQVLIDAMQAGSLPIEIVGVISNVKDAYAVTRAQQAG
CCCCCCCCCEEEEEEEECCCCCCEEEEEHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHH
IATAVFSHITEGENAGKRMGIKTFERHASAQLNDWQPDLVVLAGFMRVLSDDFISSSPAP
HHHHHHHHHHCCCCCCHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
MINLHPSLLPKYKGLDTHQRVLQSSDVHHGCSVHVVTAELDAGQVLTQAMLAVDHSESAQ
EEECCHHHCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCHH
GLQARVQKLEHQVLPWTILLIAHGVLDIKAINEQTAATAYLPELPLKLWLDS
HHHHHHHHHHHHHCCHHHHHHHHCHHEEEECCCHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301838; 9205837; 9278503; 10954745; 2204419; 1522592; 1631098; 9698564; 10606510 [H]