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The map label for this gene is ggt [H]

Identifier: 148653175

GI number: 148653175

Start: 1683526

End: 1685379

Strand: Direct

Name: ggt [H]

Synonym: PsycPRwf_1373

Alternate gene names: 148653175

Gene position: 1683526-1685379 (Clockwise)

Preceding gene: 148653174

Following gene: 148653182

Centisome position: 56.51

GC content: 48.87

Gene sequence:

>1854_bases
ATGAAAAAACACCCGTTACCGTCTTATCACAAGCTGGTTACCGCTTTAGCGTTATCCAGCTTATTAAGTTTCGGATTTGG
CTCAACTGCGGCGGCTGACACCCAAGCGCTACAGATCTTTGAAACCAAAACCTTAAAAGCCCTTCCCCCCTCTAGCCAGA
CAACTGCTCTTAAACCCACGAGCACCACGGCAAGCTTAGATGACACTACTATATTTTCACCCGATGCCATTCACCACCCG
CTATGGGCAAAAAATGGCATGGTGGCATCTCAAGAAGCACTGGCTTCAGAGATTGGCTTGCAAATCCTCAAAGATGGCGG
CAATGCAGTAGATGCCGCCGTGGCTGTCGGCTTTGCATTGGCAGTCACCTTACCGCGCGCAGGCAATATCGGTGGTGGTG
GCTTTATGATGATTTATGATGCCAAAACCGGTAAAACTGTGGCTCTGGATTATCGTGAAAAGGCGCCGATTAAGGCATAC
AAGGACATGTATCTGGGCGCAGATGGAGAAGCAGACGCTGAGCTGTCTCGCTATCATGGTTTGGCTGTTGGCGTACCAGG
TACCGTGGCAGGCCTGGTCACAGCACTTGAGCAATTTGGCAGTATGCCGCTAAGTAAAGTCATGGCACCCGCCATTGACT
TAGCTGAGAATGGCATTGATGTGACACCTGGCCTGGCTGATTCATTGAACGCCTTAGAGGACAGACTAAAAAAATGGCCC
AGTACGGCTAAGATATTCTTTAAGCCCGACGGCAGTGCTTATGACGTCGGCGAGCGTTTGTATCAGCCACAGCTTGCCGC
CTCGCTTAAGCTCATTGCCAAACAAGGTGCCGATGGATTTTATAAAAGCAAAACAGCACAGCAAATCGTCAAAGCAGTTA
ATGAAGCAGGCGGTATCATGAGCCTACAAGACTTTGCTAATTACAAAGCGGTGATGCGTGAGCCTGTACGTGGTACCTAC
CGCGGCTATGAGATTGCCTCTATGCCGCCACCATCATCGGGGGGTGCCCACATTGTGCAGATTCTTAATATCTTGGAGGG
TTATCCGCTTAAGGACTATGGGCAAAACAGTGCCCAGACCATTCATTTAATGTCTGAGGCGATGCAATTGGCCTATGCAG
ATCGTGCAGAGTATCTGGGTGATTCAGACTTTATCGATGTTCCCCTATCTGGTATTACTTCTAAGGCTTATACTCAGAAG
CTTCGAGCAAAGATTAATCCCAATAAAGCCACCCCTGCCAGCCAAGTTAAGCCGGACAACCCTGTCCCTTACGAAAGCGA
TGAGACCACGCACTTCTCTATTGTCGATAAATATGGCAATGCGGTGGCCAATACCTATACCCTAAACTTCTCTTATGGCA
CCGGCCTAGTCGCTGAAGGCACAGGGATCTTATTAAATAACGAAATGGATGACTTCTCGGCCAAACCTGGCACCGCAAAT
GCTTATGGCTTATTGGGTAATGACGCCAATGCTGTTGCTGCCAGCAAGCGCCCGCTGTCCTCTATGAGTCCGACAATTGT
CTTTAAAGACAATCAGCCTTACATAGTGACTGGCAGTCCAGGTGGTAGCCGTATTATCACCACAGTGACTCAGATAATCT
CCAACGTCATTGACCATGACATGAACATTGCGGACGCCACTCATGCTCCGCGTATCCATGATCAGTGGATGCCGGATGAA
ATTCGTATTGAAAAAGCGCTTAATGTGGACACCATCCGCAAGCTTGAATCCATGGGCCATAAGATATCTCCAAAAGAGAC
CATGGGCTCTACTCAATCCATCATGGTAACCCCAAAAGGCAAATATGGGGCCACTGATCCAAGACAGGTAGATGCTGCAG
TAGTGGGCTACTAA

Upstream 100 bases:

>100_bases
CTTTAATGAGAGTTTAATGAGCTTTTAATAAACTTTGCCATTATGTCATATCGCGCCAGCATGACCGCATCAAGCCACTC
ATGGAAGAGAGGATTGTTCG

Downstream 100 bases:

>100_bases
TCAGCCACTAATTAAACGAGTATTTACTTAACCGCCACTTGATCGACAAAAACGCCGTAGCCTGACTGCGGCATTTTATC
GACTGGAATAAACTGTAGCG

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MKKHPLPSYHKLVTALALSSLLSFGFGSTAAADTQALQIFETKTLKALPPSSQTTALKPTSTTASLDDTTIFSPDAIHHP
LWAKNGMVASQEALASEIGLQILKDGGNAVDAAVAVGFALAVTLPRAGNIGGGGFMMIYDAKTGKTVALDYREKAPIKAY
KDMYLGADGEADAELSRYHGLAVGVPGTVAGLVTALEQFGSMPLSKVMAPAIDLAENGIDVTPGLADSLNALEDRLKKWP
STAKIFFKPDGSAYDVGERLYQPQLAASLKLIAKQGADGFYKSKTAQQIVKAVNEAGGIMSLQDFANYKAVMREPVRGTY
RGYEIASMPPPSSGGAHIVQILNILEGYPLKDYGQNSAQTIHLMSEAMQLAYADRAEYLGDSDFIDVPLSGITSKAYTQK
LRAKINPNKATPASQVKPDNPVPYESDETTHFSIVDKYGNAVANTYTLNFSYGTGLVAEGTGILLNNEMDDFSAKPGTAN
AYGLLGNDANAVAASKRPLSSMSPTIVFKDNQPYIVTGSPGGSRIITTVTQIISNVIDHDMNIADATHAPRIHDQWMPDE
IRIEKALNVDTIRKLESMGHKISPKETMGSTQSIMVTPKGKYGATDPRQVDAAVVGY

Sequences:

>Translated_617_residues
MKKHPLPSYHKLVTALALSSLLSFGFGSTAAADTQALQIFETKTLKALPPSSQTTALKPTSTTASLDDTTIFSPDAIHHP
LWAKNGMVASQEALASEIGLQILKDGGNAVDAAVAVGFALAVTLPRAGNIGGGGFMMIYDAKTGKTVALDYREKAPIKAY
KDMYLGADGEADAELSRYHGLAVGVPGTVAGLVTALEQFGSMPLSKVMAPAIDLAENGIDVTPGLADSLNALEDRLKKWP
STAKIFFKPDGSAYDVGERLYQPQLAASLKLIAKQGADGFYKSKTAQQIVKAVNEAGGIMSLQDFANYKAVMREPVRGTY
RGYEIASMPPPSSGGAHIVQILNILEGYPLKDYGQNSAQTIHLMSEAMQLAYADRAEYLGDSDFIDVPLSGITSKAYTQK
LRAKINPNKATPASQVKPDNPVPYESDETTHFSIVDKYGNAVANTYTLNFSYGTGLVAEGTGILLNNEMDDFSAKPGTAN
AYGLLGNDANAVAASKRPLSSMSPTIVFKDNQPYIVTGSPGGSRIITTVTQIISNVIDHDMNIADATHAPRIHDQWMPDE
IRIEKALNVDTIRKLESMGHKISPKETMGSTQSIMVTPKGKYGATDPRQVDAAVVGY
>Mature_617_residues
MKKHPLPSYHKLVTALALSSLLSFGFGSTAAADTQALQIFETKTLKALPPSSQTTALKPTSTTASLDDTTIFSPDAIHHP
LWAKNGMVASQEALASEIGLQILKDGGNAVDAAVAVGFALAVTLPRAGNIGGGGFMMIYDAKTGKTVALDYREKAPIKAY
KDMYLGADGEADAELSRYHGLAVGVPGTVAGLVTALEQFGSMPLSKVMAPAIDLAENGIDVTPGLADSLNALEDRLKKWP
STAKIFFKPDGSAYDVGERLYQPQLAASLKLIAKQGADGFYKSKTAQQIVKAVNEAGGIMSLQDFANYKAVMREPVRGTY
RGYEIASMPPPSSGGAHIVQILNILEGYPLKDYGQNSAQTIHLMSEAMQLAYADRAEYLGDSDFIDVPLSGITSKAYTQK
LRAKINPNKATPASQVKPDNPVPYESDETTHFSIVDKYGNAVANTYTLNFSYGTGLVAEGTGILLNNEMDDFSAKPGTAN
AYGLLGNDANAVAASKRPLSSMSPTIVFKDNQPYIVTGSPGGSRIITTVTQIISNVIDHDMNIADATHAPRIHDQWMPDE
IRIEKALNVDTIRKLESMGHKISPKETMGSTQSIMVTPKGKYGATDPRQVDAAVVGY

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=531, Percent_Identity=34.8399246704331, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI73915090, Length=531, Percent_Identity=34.8399246704331, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI73915096, Length=531, Percent_Identity=34.8399246704331, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI73915094, Length=531, Percent_Identity=34.8399246704331, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI113429324, Length=525, Percent_Identity=33.3333333333333, Blast_Score=253, Evalue=4e-67,
Organism=Homo sapiens, GI113429326, Length=529, Percent_Identity=32.703213610586, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI109148539, Length=543, Percent_Identity=32.2283609576427, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI153266885, Length=478, Percent_Identity=26.5690376569038, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI153266901, Length=479, Percent_Identity=26.7223382045929, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI153266907, Length=478, Percent_Identity=25.1046025104602, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI30581157, Length=221, Percent_Identity=34.841628959276, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI30581155, Length=221, Percent_Identity=34.841628959276, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI218505805, Length=219, Percent_Identity=31.0502283105023, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI310124095, Length=219, Percent_Identity=28.7671232876712, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1789856, Length=542, Percent_Identity=55.719557195572, Blast_Score=611, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI72000294, Length=549, Percent_Identity=34.0619307832423, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI212646519, Length=549, Percent_Identity=34.0619307832423, Blast_Score=261, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI17506189, Length=511, Percent_Identity=35.0293542074364, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17542894, Length=510, Percent_Identity=32.5490196078431, Blast_Score=223, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI193208245, Length=506, Percent_Identity=30.8300395256917, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI193208247, Length=508, Percent_Identity=31.6929133858268, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17564448, Length=429, Percent_Identity=25.8741258741259, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI72001497, Length=230, Percent_Identity=27.3913043478261, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI72001495, Length=230, Percent_Identity=27.3913043478261, Blast_Score=85, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323330, Length=562, Percent_Identity=27.9359430604982, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24642670, Length=509, Percent_Identity=31.434184675835, Blast_Score=221, Evalue=8e-58,
Organism=Drosophila melanogaster, GI24642666, Length=509, Percent_Identity=31.434184675835, Blast_Score=221, Evalue=8e-58,
Organism=Drosophila melanogaster, GI161077496, Length=540, Percent_Identity=30.3703703703704, Blast_Score=221, Evalue=8e-58,
Organism=Drosophila melanogaster, GI45551474, Length=509, Percent_Identity=31.434184675835, Blast_Score=221, Evalue=9e-58,
Organism=Drosophila melanogaster, GI161077880, Length=509, Percent_Identity=31.434184675835, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI161077878, Length=509, Percent_Identity=31.434184675835, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI18859893, Length=522, Percent_Identity=30.2681992337165, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI18859741, Length=516, Percent_Identity=28.1007751937984, Blast_Score=192, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 65746; Mature: 65746

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00462 G_GLU_TRANSPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHPLPSYHKLVTALALSSLLSFGFGSTAAADTQALQIFETKTLKALPPSSQTTALKPT
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEHHCHHCCCCCCCCCEEECCC
STTASLDDTTIFSPDAIHHPLWAKNGMVASQEALASEIGLQILKDGGNAVDAAVAVGFAL
CCCCCCCCCEEECCCHHCCCCCCCCCCCHHHHHHHHHHCHHEEECCCCHHHHHHHHHHHH
AVTLPRAGNIGGGGFMMIYDAKTGKTVALDYREKAPIKAYKDMYLGADGEADAELSRYHG
EEECCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHEECCCCCCCHHHHHHCC
LAVGVPGTVAGLVTALEQFGSMPLSKVMAPAIDLAENGIDVTPGLADSLNALEDRLKKWP
EEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
STAKIFFKPDGSAYDVGERLYQPQLAASLKLIAKQGADGFYKSKTAQQIVKAVNEAGGIM
CCEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
SLQDFANYKAVMREPVRGTYRGYEIASMPPPSSGGAHIVQILNILEGYPLKDYGQNSAQT
EHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCHHCCCCCHHH
IHLMSEAMQLAYADRAEYLGDSDFIDVPLSGITSKAYTQKLRAKINPNKATPASQVKPDN
HHHHHHHHHHHHHHHHHHCCCCCEEECCCHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PVPYESDETTHFSIVDKYGNAVANTYTLNFSYGTGLVAEGTGILLNNEMDDFSAKPGTAN
CCCCCCCCCEEEEEEHHHCCCEEEEEEEEEECCCCEEECCCEEEEECCCCCCCCCCCCCC
AYGLLGNDANAVAASKRPLSSMSPTIVFKDNQPYIVTGSPGGSRIITTVTQIISNVIDHD
EEEEECCCCCHHCCCCCCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHCC
MNIADATHAPRIHDQWMPDEIRIEKALNVDTIRKLESMGHKISPKETMGSTQSIMVTPKG
CCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCHHHCCCCCEEEEECCC
KYGATDPRQVDAAVVGY
CCCCCCCHHCCEEECCC
>Mature Secondary Structure
MKKHPLPSYHKLVTALALSSLLSFGFGSTAAADTQALQIFETKTLKALPPSSQTTALKPT
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEHHCHHCCCCCCCCCEEECCC
STTASLDDTTIFSPDAIHHPLWAKNGMVASQEALASEIGLQILKDGGNAVDAAVAVGFAL
CCCCCCCCCEEECCCHHCCCCCCCCCCCHHHHHHHHHHCHHEEECCCCHHHHHHHHHHHH
AVTLPRAGNIGGGGFMMIYDAKTGKTVALDYREKAPIKAYKDMYLGADGEADAELSRYHG
EEECCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHEECCCCCCCHHHHHHCC
LAVGVPGTVAGLVTALEQFGSMPLSKVMAPAIDLAENGIDVTPGLADSLNALEDRLKKWP
EEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
STAKIFFKPDGSAYDVGERLYQPQLAASLKLIAKQGADGFYKSKTAQQIVKAVNEAGGIM
CCEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
SLQDFANYKAVMREPVRGTYRGYEIASMPPPSSGGAHIVQILNILEGYPLKDYGQNSAQT
EHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCHHCCCCCHHH
IHLMSEAMQLAYADRAEYLGDSDFIDVPLSGITSKAYTQKLRAKINPNKATPASQVKPDN
HHHHHHHHHHHHHHHHHHCCCCCEEECCCHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PVPYESDETTHFSIVDKYGNAVANTYTLNFSYGTGLVAEGTGILLNNEMDDFSAKPGTAN
CCCCCCCCCEEEEEEHHHCCCEEEEEEEEEECCCCEEECCCEEEEECCCCCCCCCCCCCC
AYGLLGNDANAVAASKRPLSSMSPTIVFKDNQPYIVTGSPGGSRIITTVTQIISNVIDHD
EEEEECCCCCHHCCCCCCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHCC
MNIADATHAPRIHDQWMPDEIRIEKALNVDTIRKLESMGHKISPKETMGSTQSIMVTPKG
CCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCHHHCCCCCEEEEECCC
KYGATDPRQVDAAVVGY
CCCCCCCHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2570061; 9278503; 8041620; 1360205 [H]