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The map label for this gene is lipB [H]

Identifier: 148653182

GI number: 148653182

Start: 1693750

End: 1694553

Strand: Direct

Name: lipB [H]

Synonym: PsycPRwf_1380

Alternate gene names: 148653182

Gene position: 1693750-1694553 (Clockwise)

Preceding gene: 148653175

Following gene: 148653183

Centisome position: 56.86

GC content: 47.26

Gene sequence:

>804_bases
ATGATTTCTACTCACAACCAAACCCAAAGCGACGCTATAGGCGACGCCAAAGCGCCAAGCGCTTTTAAATTACGTACCTT
AATTGATGCCGATTATGAGCAGACGCACGCTGCTATGCTGAGCCATACTTTAAAGCGTATCGAACAAAAACGCCAAGGCA
TTATCACCCCCGATGAGCTGTGGATTGTCGAGCATAAGGATGTTTATACCCTCGGTCAAGCCGGCAAAGAAGAGCACATA
TTACAGCGCGGTGATACACCCATTATCCATACCGATCGTGGTGGCCAAGTCACCTGGCATGGCAAAGGGCAATTGGTCAT
TTATTGGCTGATTGACTTAAATAATGCCGGCTGGTCGGTGCGAGACTTGGTATCACATGCAGAGCAAAGCATTGAAGATG
TGTTAAATACGGTATTAAGCCGTCAGCCAGCCGCTACAGAGTTTTATGCCAAAGCCCGTAAAGATGCGCCCGGTGTTTAT
ATTTATAACAAAGATGAGCTGATGCTCGGTAAGATTGCCTCATTGGGCTTTAAGATTAAGCACGGCTTTAGCTACCATGG
CATTGCACTAAACCTCACTTGTGATCTGGGTGCCTTTAATGCCATTAACCCTTGTGGTTATGCGGGCATGCAAATGCTTA
GATTGGCTGATTTTGTGGCGTTAAATAGCATTGACACCTCCCCATATCATGGCTTTGAGGTGCTGCCAGACGCCGTCACT
GAGCTTGAGGTGACCAAGCTGCTGCTGACGAATATTATCCAGCGTGATATGGGTGTCATTTCTTTGCGCAGCGCTGCTCC
TTAA

Upstream 100 bases:

>100_bases
ACGACACTTAAAAAAAGCAATCAATATAGCAGTGTTCAGCTATGGCGAGCTCGATGACCCCATGATATGCTATAACCTCC
AAATAAAACAATAGCTGATT

Downstream 100 bases:

>100_bases
TCCTACGCTACTTTTGAGAGCCTGTTATGAATACAGATTTCCCCGCCCCTAATTTACAAGCATCCCATCTGAGCCTAACG
GATGCACCAAAGCTCACCGC

Product: lipoate-protein ligase B

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MISTHNQTQSDAIGDAKAPSAFKLRTLIDADYEQTHAAMLSHTLKRIEQKRQGIITPDELWIVEHKDVYTLGQAGKEEHI
LQRGDTPIIHTDRGGQVTWHGKGQLVIYWLIDLNNAGWSVRDLVSHAEQSIEDVLNTVLSRQPAATEFYAKARKDAPGVY
IYNKDELMLGKIASLGFKIKHGFSYHGIALNLTCDLGAFNAINPCGYAGMQMLRLADFVALNSIDTSPYHGFEVLPDAVT
ELEVTKLLLTNIIQRDMGVISLRSAAP

Sequences:

>Translated_267_residues
MISTHNQTQSDAIGDAKAPSAFKLRTLIDADYEQTHAAMLSHTLKRIEQKRQGIITPDELWIVEHKDVYTLGQAGKEEHI
LQRGDTPIIHTDRGGQVTWHGKGQLVIYWLIDLNNAGWSVRDLVSHAEQSIEDVLNTVLSRQPAATEFYAKARKDAPGVY
IYNKDELMLGKIASLGFKIKHGFSYHGIALNLTCDLGAFNAINPCGYAGMQMLRLADFVALNSIDTSPYHGFEVLPDAVT
ELEVTKLLLTNIIQRDMGVISLRSAAP
>Mature_267_residues
MISTHNQTQSDAIGDAKAPSAFKLRTLIDADYEQTHAAMLSHTLKRIEQKRQGIITPDELWIVEHKDVYTLGQAGKEEHI
LQRGDTPIIHTDRGGQVTWHGKGQLVIYWLIDLNNAGWSVRDLVSHAEQSIEDVLNTVLSRQPAATEFYAKARKDAPGVY
IYNKDELMLGKIASLGFKIKHGFSYHGIALNLTCDLGAFNAINPCGYAGMQMLRLADFVALNSIDTSPYHGFEVLPDAVT
ELEVTKLLLTNIIQRDMGVISLRSAAP

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Escherichia coli, GI87081767, Length=195, Percent_Identity=46.1538461538462, Blast_Score=159, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6323268, Length=260, Percent_Identity=29.2307692307692, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355483, Length=181, Percent_Identity=30.3867403314917, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 29609; Mature: 29609

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTHNQTQSDAIGDAKAPSAFKLRTLIDADYEQTHAAMLSHTLKRIEQKRQGIITPDEL
CCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
WIVEHKDVYTLGQAGKEEHILQRGDTPIIHTDRGGQVTWHGKGQLVIYWLIDLNNAGWSV
EEEECCCEEECCCCCCHHHHHHCCCCCEEECCCCCEEEEECCCCEEEEEEEEECCCCCCH
RDLVSHAEQSIEDVLNTVLSRQPAATEFYAKARKDAPGVYIYNKDELMLGKIASLGFKIK
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCCCCHHHHHHHCCEEEE
HGFSYHGIALNLTCDLGAFNAINPCGYAGMQMLRLADFVALNSIDTSPYHGFEVLPDAVT
CCCEECCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
ELEVTKLLLTNIIQRDMGVISLRSAAP
HHHHHHHHHHHHHHHCCCEEEECCCCC
>Mature Secondary Structure
MISTHNQTQSDAIGDAKAPSAFKLRTLIDADYEQTHAAMLSHTLKRIEQKRQGIITPDEL
CCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
WIVEHKDVYTLGQAGKEEHILQRGDTPIIHTDRGGQVTWHGKGQLVIYWLIDLNNAGWSV
EEEECCCEEECCCCCCHHHHHHCCCCCEEECCCCCEEEEECCCCEEEEEEEEECCCCCCH
RDLVSHAEQSIEDVLNTVLSRQPAATEFYAKARKDAPGVYIYNKDELMLGKIASLGFKIK
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCCCCHHHHHHHCCEEEE
HGFSYHGIALNLTCDLGAFNAINPCGYAGMQMLRLADFVALNSIDTSPYHGFEVLPDAVT
CCCEECCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
ELEVTKLLLTNIIQRDMGVISLRSAAP
HHHHHHHHHHHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA