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The map label for this gene is ubiB [C]

Identifier: 148652822

GI number: 148652822

Start: 1208098

End: 1209396

Strand: Direct

Name: ubiB [C]

Synonym: PsycPRwf_1015

Alternate gene names: 148652822

Gene position: 1208098-1209396 (Clockwise)

Preceding gene: 148652821

Following gene: 148652823

Centisome position: 40.55

GC content: 49.5

Gene sequence:

>1299_bases
ATGTCAAATTTATTGAAAAAATCCTTCAATGTTGTCAATCGTGTCCGTCACACTGCCAGTGTGGCCGGCTTATCTGCATT
GCGTGTGGCCAAAGGTGAGCGTCCAGATGCGGTCATGCTGCGTGAGACGTTCGAGCAGCTTGGCACCACTTATATCAAAA
TTGGTCAGTTTATCGCCAGCACGCCCTCCTTGTTTCCGCGTGACTATGTGATTGCCTTTCAAGGCTGCTTAGACCAGACC
ACGCCGCTGCCGTATCAGTATATTGAAGGGGTATTAAAGCAAGAGCTGTTAACAGACCATCACAGCTTAGATGAGTTGTT
TTTGCATATCGATGAGACGCCGCTGGCGTCTGCTAGTATCGCCCAAGTGCACGCGGCAACGCTGCGTGATGGCCGTGATG
TGGTGCTAAAAGTCCAAAAGCCGGATGTCGATGTGATCATGCAGACCGATCTTGGGGTGCTACACGGGGTGACCAAGATT
ATGGAGCGCTTAATGCCGCAAATGCGTTTTGCCAGTATCTCGCCGATTATCGATGAGATTCGCACCCGTATGTTGGCTGA
GACCGACTTTATCGCTGAGGCGTCTAATATCCGTGATTTTCAGCAGTTTTTACAGATGACGGGCAATCAAAAGGTGGTGG
CGCCTGAAGTGGTGGATGAGCTGACCACCAAAAAAGTGCTGACCATGAGCCGCTTGCATGGCATCTCTATGGTTGATGAG
GTGGCGATGCGCCAATATAGCGCAGATCCTGCGCAAGTGATGGCCGATACGCTCAACACTTGGTTTGCAAGCCTAATGAT
GTGCAACAGCTTCCATGCTGACCTGCACGCTGGCAACTTAATGCTGCTTAAAGATGGGCGTATTGGCTTTATTGATTTTG
GTATTGTCGGTAAGCTAAAGCCTGAAAGCTGGCAAGCGTGTATGGGTATGATGCAAGCGCTACAGGACAATGATTATGTG
ACCATGGCCGGCTGTATGATTGATATGGGCATGACTCATGATCGTGAGCAAGTCGATCAGGCACAGCTGGCCGGTGATTT
GGCAAAAATGATTACCCGCATTATGGCAGAGGATAAAACCTATACCAGTGGCAAGCCATTTAATACCAAAGAACAGGCCG
ATGAGCTAAACAAAATGATGCTAGAGATTGTTGAGGTCGGCAAACGCCACGGTATTCATTTCCCGCGCGACTTTGCGCTG
CTGACCAAGCAAATGCTGTATTTTGACCGCTTTATGCGCACGCTTGCACCCGACATGGATATGTTTAATGATGCCCGCGT
CAGCTTGCTGGGCAGATAA

Upstream 100 bases:

>100_bases
CTATAATATAGCGGCACTTTGCTCATGTTACAGACGCATTAAGTTATAAATTTTTACGACCTAATGCCTGACCTTCTTTT
GTTAATAGACTCAAAATCCT

Downstream 100 bases:

>100_bases
ATAGTGAAAAAGGGCGCCGCGCTAGGGTAGGGCAAATAAGTAGAGGACTGTATACGCGCCCGATGGATAATCTTTTGATT
AGTAATATACGTTTTTGATT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSNLLKKSFNVVNRVRHTASVAGLSALRVAKGERPDAVMLRETFEQLGTTYIKIGQFIASTPSLFPRDYVIAFQGCLDQT
TPLPYQYIEGVLKQELLTDHHSLDELFLHIDETPLASASIAQVHAATLRDGRDVVLKVQKPDVDVIMQTDLGVLHGVTKI
MERLMPQMRFASISPIIDEIRTRMLAETDFIAEASNIRDFQQFLQMTGNQKVVAPEVVDELTTKKVLTMSRLHGISMVDE
VAMRQYSADPAQVMADTLNTWFASLMMCNSFHADLHAGNLMLLKDGRIGFIDFGIVGKLKPESWQACMGMMQALQDNDYV
TMAGCMIDMGMTHDREQVDQAQLAGDLAKMITRIMAEDKTYTSGKPFNTKEQADELNKMMLEIVEVGKRHGIHFPRDFAL
LTKQMLYFDRFMRTLAPDMDMFNDARVSLLGR

Sequences:

>Translated_432_residues
MSNLLKKSFNVVNRVRHTASVAGLSALRVAKGERPDAVMLRETFEQLGTTYIKIGQFIASTPSLFPRDYVIAFQGCLDQT
TPLPYQYIEGVLKQELLTDHHSLDELFLHIDETPLASASIAQVHAATLRDGRDVVLKVQKPDVDVIMQTDLGVLHGVTKI
MERLMPQMRFASISPIIDEIRTRMLAETDFIAEASNIRDFQQFLQMTGNQKVVAPEVVDELTTKKVLTMSRLHGISMVDE
VAMRQYSADPAQVMADTLNTWFASLMMCNSFHADLHAGNLMLLKDGRIGFIDFGIVGKLKPESWQACMGMMQALQDNDYV
TMAGCMIDMGMTHDREQVDQAQLAGDLAKMITRIMAEDKTYTSGKPFNTKEQADELNKMMLEIVEVGKRHGIHFPRDFAL
LTKQMLYFDRFMRTLAPDMDMFNDARVSLLGR
>Mature_431_residues
SNLLKKSFNVVNRVRHTASVAGLSALRVAKGERPDAVMLRETFEQLGTTYIKIGQFIASTPSLFPRDYVIAFQGCLDQTT
PLPYQYIEGVLKQELLTDHHSLDELFLHIDETPLASASIAQVHAATLRDGRDVVLKVQKPDVDVIMQTDLGVLHGVTKIM
ERLMPQMRFASISPIIDEIRTRMLAETDFIAEASNIRDFQQFLQMTGNQKVVAPEVVDELTTKKVLTMSRLHGISMVDEV
AMRQYSADPAQVMADTLNTWFASLMMCNSFHADLHAGNLMLLKDGRIGFIDFGIVGKLKPESWQACMGMMQALQDNDYVT
MAGCMIDMGMTHDREQVDQAQLAGDLAKMITRIMAEDKTYTSGKPFNTKEQADELNKMMLEIVEVGKRHGIHFPRDFALL
TKQMLYFDRFMRTLAPDMDMFNDARVSLLGR

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=259, Percent_Identity=29.3436293436293, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI217035081, Length=257, Percent_Identity=27.6264591439689, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI41393593, Length=272, Percent_Identity=27.2058823529412, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI34147522, Length=222, Percent_Identity=26.1261261261261, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI27363457, Length=147, Percent_Identity=34.0136054421769, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI217416386, Length=147, Percent_Identity=34.0136054421769, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI2367309, Length=405, Percent_Identity=26.4197530864197, Blast_Score=129, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17559152, Length=387, Percent_Identity=25.0645994832041, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI32565180, Length=200, Percent_Identity=31, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323282, Length=261, Percent_Identity=25.2873563218391, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321319, Length=246, Percent_Identity=27.2357723577236, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6325148, Length=449, Percent_Identity=20.7126948775056, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI22024280, Length=325, Percent_Identity=23.0769230769231, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24662575, Length=263, Percent_Identity=24.7148288973384, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI18859849, Length=276, Percent_Identity=26.4492753623188, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 48698; Mature: 48567

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.9 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLLKKSFNVVNRVRHTASVAGLSALRVAKGERPDAVMLRETFEQLGTTYIKIGQFIAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHC
TPSLFPRDYVIAFQGCLDQTTPLPYQYIEGVLKQELLTDHHSLDELFLHIDETPLASASI
CCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCHHH
AQVHAATLRDGRDVVLKVQKPDVDVIMQTDLGVLHGVTKIMERLMPQMRFASISPIIDEI
HHHHHHHHCCCCEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTRMLAETDFIAEASNIRDFQQFLQMTGNQKVVAPEVVDELTTKKVLTMSRLHGISMVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMRQYSADPAQVMADTLNTWFASLMMCNSFHADLHAGNLMLLKDGRIGFIDFGIVGKLK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCEECCC
PESWQACMGMMQALQDNDYVTMAGCMIDMGMTHDREQVDQAQLAGDLAKMITRIMAEDKT
CHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
YTSGKPFNTKEQADELNKMMLEIVEVGKRHGIHFPRDFALLTKQMLYFDRFMRTLAPDMD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
MFNDARVSLLGR
CCCCHHHHHCCC
>Mature Secondary Structure 
SNLLKKSFNVVNRVRHTASVAGLSALRVAKGERPDAVMLRETFEQLGTTYIKIGQFIAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHC
TPSLFPRDYVIAFQGCLDQTTPLPYQYIEGVLKQELLTDHHSLDELFLHIDETPLASASI
CCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCHHH
AQVHAATLRDGRDVVLKVQKPDVDVIMQTDLGVLHGVTKIMERLMPQMRFASISPIIDEI
HHHHHHHHCCCCEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTRMLAETDFIAEASNIRDFQQFLQMTGNQKVVAPEVVDELTTKKVLTMSRLHGISMVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMRQYSADPAQVMADTLNTWFASLMMCNSFHADLHAGNLMLLKDGRIGFIDFGIVGKLK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCEECCC
PESWQACMGMMQALQDNDYVTMAGCMIDMGMTHDREQVDQAQLAGDLAKMITRIMAEDKT
CHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
YTSGKPFNTKEQADELNKMMLEIVEVGKRHGIHFPRDFALLTKQMLYFDRFMRTLAPDMD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
MFNDARVSLLGR
CCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]