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The map label for this gene is pitA [C]

Identifier: 148652597

GI number: 148652597

Start: 939611

End: 941218

Strand: Direct

Name: pitA [C]

Synonym: PsycPRwf_0788

Alternate gene names: 148652597

Gene position: 939611-941218 (Clockwise)

Preceding gene: 148652596

Following gene: 148652599

Centisome position: 31.54

GC content: 45.46

Gene sequence:

>1608_bases
ATGCTTCCAAAGTCAACTACATCAAGTAGCGCCCAGTTTACGGGTTCGAAAAAAGCTAATATACTTTTTGGTCTATTCCT
GTTTGTCATGACCGCATATTTTATGTGGTGGGGCTTGGATTATACCAATCACCAGCAGACGCCATTATTTATCGTGGCTA
CCGTGTTTGGCATATTTATGGCCTTCAACATTGGGGGGAACGATGTTGCGAACTCCTTTGGTACATCGGTAGGCGCGGGT
ACTTTATCCATTCCGCAAGCCTTGGCCATTGCCGCCATTTTTGAGGTATCTGGGGCGGTGCTTGCTGGTGCTGAGGTAAC
CGATACCATTCGTAAAGGTATTGTTGATTTAGATGCCTTATCAGTGACGCCCAACCAGTTCATCTATGTGATGCTATCGG
CGTTGATTGCCGCGGCGTTCTGGCTATTGTTTGCTACCAAAAAAGGCTTACCGGTTTCTACCACGCACTCCATTATTGGT
GGGGTAGTGGGCAGCTCGATTGTTATGGGTATTCAAGTGGGCGGGCCTTCATTGGCATTTTCTACCGTGCACTGGGATCA
AATAGGACAAATTGCTTTATCTTGGGTCTTGTCACCTTTATTAGGTGGTATACTGGCGTATGTGCTATACAGCCAAATTA
AAGTCAATATTTTGTCTTATAATGACCGTGTTGAAGCCCGAGTTAAAGAGCTTAAAGCAGCCAAAAAAGCACTAAAAAAA
CGCCATAAAGAATGGATCAATGAGTTGGCTGAGTCGCTACAGGTGTCCTATACGTCCAAGATGGTACGTGACCAAGAGAT
TTATAAAGACGAGGATACCGAACGAGATGATCTGGAGACAGACTACTATCAAGAGCTTTATGACATCGAGCGTGAAAGAG
ACAGCATTGATACTCTAAAAGCATTGCGTCAATGGGTGCCTCTGGTGGCCGCATTAGGCGGTGTGGTTATGACTTCTATG
GTGGTGTTTAAAGGCCTACAAAACGTTGATATGAGTCTGACCACGTTAAATGGCTTCTTAATCATGATTATGATTGGGGC
GCTTATTTGGCTGACGACCTTTATTTATACTAAGAGTATTAAAGGTAAGCAGAAAGAAGACTTGGGCCGTGCTACCTTTA
TTTTGTTTAGCTGGATGCAGGTATTTACTGCCGCAGGCTTTGCATTTAGCCATGGTGCCAATGATATCGCCAACGCTGTG
GGTCCTTTTGCAGCCATCATGGACGTTATTCGTACCAATAGTATCGCCAGCGAAGCGGCGGTACCTAGCGCGGTTATGGT
TACCTTTGGTGTCGCCTTAATTGTGGGCTTATGGTTTATTGGTAAAGAGGTTATCCAAACTGTGGGTACCAATTTGGCCG
AGATGCATCCTGCGTCAGGCTTCTCAGCTGAGTTATCAGCAGCAGCGGTAGTCATGGGCGCCTCTATGCTGGGTCTACCT
GTTTCTAGTACGCATGTGCTTGTGGGTGCGGTATTGGGTATTGGTATGGTGAATAAAAACACCAACTGGGGTTTGATGAA
GCCAATCGGTTTGGCTTGGGTAGTTACTTTACCTGCTGCCGCTACCATGTCTATGGTCAGCTACTTAATTTTAAGCAACG
TATTTTAA

Upstream 100 bases:

>100_bases
CAGTTGTCGTATGTCTCGATCAAACGGACTTGTACTAATTCATTGAAGCCCCGATCTCTCGGGGTTTTACATTTTCACAT
CCGATTGGCTCAGAAATCTC

Downstream 100 bases:

>100_bases
GTGTATAGAGCCCCTAAGCGTCGCTAGATAGACTTAAAAAGCCCTCAATTAGTGTGAGGGCTTTTTTGTGCTTGGCTTAA
TAGCTTATTAAAAGATAAGG

Product: phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MLPKSTTSSSAQFTGSKKANILFGLFLFVMTAYFMWWGLDYTNHQQTPLFIVATVFGIFMAFNIGGNDVANSFGTSVGAG
TLSIPQALAIAAIFEVSGAVLAGAEVTDTIRKGIVDLDALSVTPNQFIYVMLSALIAAAFWLLFATKKGLPVSTTHSIIG
GVVGSSIVMGIQVGGPSLAFSTVHWDQIGQIALSWVLSPLLGGILAYVLYSQIKVNILSYNDRVEARVKELKAAKKALKK
RHKEWINELAESLQVSYTSKMVRDQEIYKDEDTERDDLETDYYQELYDIERERDSIDTLKALRQWVPLVAALGGVVMTSM
VVFKGLQNVDMSLTTLNGFLIMIMIGALIWLTTFIYTKSIKGKQKEDLGRATFILFSWMQVFTAAGFAFSHGANDIANAV
GPFAAIMDVIRTNSIASEAAVPSAVMVTFGVALIVGLWFIGKEVIQTVGTNLAEMHPASGFSAELSAAAVVMGASMLGLP
VSSTHVLVGAVLGIGMVNKNTNWGLMKPIGLAWVVTLPAAATMSMVSYLILSNVF

Sequences:

>Translated_535_residues
MLPKSTTSSSAQFTGSKKANILFGLFLFVMTAYFMWWGLDYTNHQQTPLFIVATVFGIFMAFNIGGNDVANSFGTSVGAG
TLSIPQALAIAAIFEVSGAVLAGAEVTDTIRKGIVDLDALSVTPNQFIYVMLSALIAAAFWLLFATKKGLPVSTTHSIIG
GVVGSSIVMGIQVGGPSLAFSTVHWDQIGQIALSWVLSPLLGGILAYVLYSQIKVNILSYNDRVEARVKELKAAKKALKK
RHKEWINELAESLQVSYTSKMVRDQEIYKDEDTERDDLETDYYQELYDIERERDSIDTLKALRQWVPLVAALGGVVMTSM
VVFKGLQNVDMSLTTLNGFLIMIMIGALIWLTTFIYTKSIKGKQKEDLGRATFILFSWMQVFTAAGFAFSHGANDIANAV
GPFAAIMDVIRTNSIASEAAVPSAVMVTFGVALIVGLWFIGKEVIQTVGTNLAEMHPASGFSAELSAAAVVMGASMLGLP
VSSTHVLVGAVLGIGMVNKNTNWGLMKPIGLAWVVTLPAAATMSMVSYLILSNVF
>Mature_535_residues
MLPKSTTSSSAQFTGSKKANILFGLFLFVMTAYFMWWGLDYTNHQQTPLFIVATVFGIFMAFNIGGNDVANSFGTSVGAG
TLSIPQALAIAAIFEVSGAVLAGAEVTDTIRKGIVDLDALSVTPNQFIYVMLSALIAAAFWLLFATKKGLPVSTTHSIIG
GVVGSSIVMGIQVGGPSLAFSTVHWDQIGQIALSWVLSPLLGGILAYVLYSQIKVNILSYNDRVEARVKELKAAKKALKK
RHKEWINELAESLQVSYTSKMVRDQEIYKDEDTERDDLETDYYQELYDIERERDSIDTLKALRQWVPLVAALGGVVMTSM
VVFKGLQNVDMSLTTLNGFLIMIMIGALIWLTTFIYTKSIKGKQKEDLGRATFILFSWMQVFTAAGFAFSHGANDIANAV
GPFAAIMDVIRTNSIASEAAVPSAVMVTFGVALIVGLWFIGKEVIQTVGTNLAEMHPASGFSAELSAAAVVMGASMLGLP
VSSTHVLVGAVLGIGMVNKNTNWGLMKPIGLAWVVTLPAAATMSMVSYLILSNVF

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=165, Percent_Identity=41.8181818181818, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI5803173, Length=168, Percent_Identity=41.0714285714286, Blast_Score=129, Evalue=9e-30,
Organism=Escherichia coli, GI1789907, Length=476, Percent_Identity=22.2689075630252, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71981576, Length=493, Percent_Identity=34.2799188640974, Blast_Score=232, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI25146401, Length=171, Percent_Identity=43.2748538011696, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32566716, Length=159, Percent_Identity=44.0251572327044, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17539280, Length=200, Percent_Identity=36.5, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17536725, Length=163, Percent_Identity=34.9693251533742, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17557328, Length=226, Percent_Identity=28.7610619469027, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6319773, Length=166, Percent_Identity=36.7469879518072, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356511, Length=184, Percent_Identity=40.2173913043478, Blast_Score=128, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 57673; Mature: 57673

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPKSTTSSSAQFTGSKKANILFGLFLFVMTAYFMWWGLDYTNHQQTPLFIVATVFGIFM
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AFNIGGNDVANSFGTSVGAGTLSIPQALAIAAIFEVSGAVLAGAEVTDTIRKGIVDLDAL
HHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHEECCHHHHHHHHCCCCCHHC
SVTPNQFIYVMLSALIAAAFWLLFATKKGLPVSTTHSIIGGVVGSSIVMGIQVGGPSLAF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCEEE
STVHWDQIGQIALSWVLSPLLGGILAYVLYSQIKVNILSYNDRVEARVKELKAAKKALKK
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHH
RHKEWINELAESLQVSYTSKMVRDQEIYKDEDTERDDLETDYYQELYDIERERDSIDTLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ALRQWVPLVAALGGVVMTSMVVFKGLQNVDMSLTTLNGFLIMIMIGALIWLTTFIYTKSI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KGKQKEDLGRATFILFSWMQVFTAAGFAFSHGANDIANAVGPFAAIMDVIRTNSIASEAA
CCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
VPSAVMVTFGVALIVGLWFIGKEVIQTVGTNLAEMHPASGFSAELSAAAVVMGASMLGLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
VSSTHVLVGAVLGIGMVNKNTNWGLMKPIGLAWVVTLPAAATMSMVSYLILSNVF
CCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLPKSTTSSSAQFTGSKKANILFGLFLFVMTAYFMWWGLDYTNHQQTPLFIVATVFGIFM
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AFNIGGNDVANSFGTSVGAGTLSIPQALAIAAIFEVSGAVLAGAEVTDTIRKGIVDLDAL
HHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHEECCHHHHHHHHCCCCCHHC
SVTPNQFIYVMLSALIAAAFWLLFATKKGLPVSTTHSIIGGVVGSSIVMGIQVGGPSLAF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCEEE
STVHWDQIGQIALSWVLSPLLGGILAYVLYSQIKVNILSYNDRVEARVKELKAAKKALKK
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHH
RHKEWINELAESLQVSYTSKMVRDQEIYKDEDTERDDLETDYYQELYDIERERDSIDTLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ALRQWVPLVAALGGVVMTSMVVFKGLQNVDMSLTTLNGFLIMIMIGALIWLTTFIYTKSI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KGKQKEDLGRATFILFSWMQVFTAAGFAFSHGANDIANAVGPFAAIMDVIRTNSIASEAA
CCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
VPSAVMVTFGVALIVGLWFIGKEVIQTVGTNLAEMHPASGFSAELSAAAVVMGASMLGLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
VSSTHVLVGAVLGIGMVNKNTNWGLMKPIGLAWVVTLPAAATMSMVSYLILSNVF
CCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]