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The map label for this gene is aroK

Identifier: 148652212

GI number: 148652212

Start: 487190

End: 487732

Strand: Direct

Name: aroK

Synonym: PsycPRwf_0400

Alternate gene names: 148652212

Gene position: 487190-487732 (Clockwise)

Preceding gene: 148652211

Following gene: 148652213

Centisome position: 16.35

GC content: 47.33

Gene sequence:

>543_bases
ATGCAATCGACATTGCCGTCATTATTTATTGTAGGCCCTATGGGAGCGGGGAAAACTACGGTTGGTAAGCTGTTGGCAAA
ACATTTGGGCCGAGATTTTATAGACAGTGATCACTATATTTGTGAGCAGACAGGCGCCGATATTCCGTGGATCTTCGAAA
AAGAGGGTGAGACGGGGTTTCGAGAGCGTGAAGCACGTGCTATTGCTGAGCTGACAGCTTTGCCCAATGTGGTATTGGCG
ACAGGTGGCGGGGTAGTGATGCAGCCACAAAATAGAGACAATCTAACCAAGCAAGGCATTACCATTTATTTGCGCGCCAA
TGTGGATGTACAGCTTAAAAGAACCGCCAAAGATAAGTCGCGTCCTTTATTAAATACCCCCAATCCTCGAGCGGTGCTGC
AGTCTTTGTTCGATGTGCGTGACCCGTTATACCGCGAAGTGGCAGATATCGTGGTGGAGACCGGTGATGGTTACCCACGC
TATATGCTCAAAAAAATCATAGAAGCGTTAAAGCAGCATTATCCTGAGCACATGAAATCCTAA

Upstream 100 bases:

>100_bases
CTATTATTAACAGCAATAATACTTTTTAAAACGGATACAGCTAACTGGGACTAAACCTATAAATGCCTGTATAATCCGTG
AATTTATGTGAGAGATAATA

Downstream 100 bases:

>100_bases
GTCTATAAACCCTTAGCGGAAAAGCGATAAGTGAGTCTGTCTTTTAGTTAGTAAGCGTATTGATTGCCCAGCGTATTGAT
ATTAAGCCTAAAATGGATGT

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MQSTLPSLFIVGPMGAGKTTVGKLLAKHLGRDFIDSDHYICEQTGADIPWIFEKEGETGFREREARAIAELTALPNVVLA
TGGGVVMQPQNRDNLTKQGITIYLRANVDVQLKRTAKDKSRPLLNTPNPRAVLQSLFDVRDPLYREVADIVVETGDGYPR
YMLKKIIEALKQHYPEHMKS

Sequences:

>Translated_180_residues
MQSTLPSLFIVGPMGAGKTTVGKLLAKHLGRDFIDSDHYICEQTGADIPWIFEKEGETGFREREARAIAELTALPNVVLA
TGGGVVMQPQNRDNLTKQGITIYLRANVDVQLKRTAKDKSRPLLNTPNPRAVLQSLFDVRDPLYREVADIVVETGDGYPR
YMLKKIIEALKQHYPEHMKS
>Mature_180_residues
MQSTLPSLFIVGPMGAGKTTVGKLLAKHLGRDFIDSDHYICEQTGADIPWIFEKEGETGFREREARAIAELTALPNVVLA
TGGGVVMQPQNRDNLTKQGITIYLRANVDVQLKRTAKDKSRPLLNTPNPRAVLQSLFDVRDPLYREVADIVVETGDGYPR
YMLKKIIEALKQHYPEHMKS

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=169, Percent_Identity=46.7455621301775, Blast_Score=166, Evalue=9e-43,
Organism=Escherichia coli, GI1786587, Length=168, Percent_Identity=38.6904761904762, Blast_Score=114, Evalue=4e-27,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_PSYWF (A5WCG4)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001279305.1
- ProteinModelPortal:   A5WCG4
- SMR:   A5WCG4
- STRING:   A5WCG4
- GeneID:   5204766
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_0400
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- ProtClustDB:   PRK00131
- BioCyc:   PSP56811:PSYCPRWF_0400-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 20132; Mature: 20132

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 37-37 BINDING 61-61 BINDING 83-83 BINDING 121-121 BINDING 140-140

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSTLPSLFIVGPMGAGKTTVGKLLAKHLGRDFIDSDHYICEQTGADIPWIFEKEGETGF
CCCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHCCCCCEEECCCCCCCCEEEECCCCCCH
REREARAIAELTALPNVVLATGGGVVMQPQNRDNLTKQGITIYLRANVDVQLKRTAKDKS
HHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCCCCCCEEEEEEECCCEEECCCCCCCC
RPLLNTPNPRAVLQSLFDVRDPLYREVADIVVETGDGYPRYMLKKIIEALKQHYPEHMKS
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQSTLPSLFIVGPMGAGKTTVGKLLAKHLGRDFIDSDHYICEQTGADIPWIFEKEGETGF
CCCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHCCCCCEEECCCCCCCCEEEECCCCCCH
REREARAIAELTALPNVVLATGGGVVMQPQNRDNLTKQGITIYLRANVDVQLKRTAKDKS
HHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCCCCCCEEEEEEECCCEEECCCCCCCC
RPLLNTPNPRAVLQSLFDVRDPLYREVADIVVETGDGYPRYMLKKIIEALKQHYPEHMKS
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA