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The map label for this gene is aroB [H]

Identifier: 148652213

GI number: 148652213

Start: 487825

End: 488925

Strand: Direct

Name: aroB [H]

Synonym: PsycPRwf_0401

Alternate gene names: 148652213

Gene position: 487825-488925 (Clockwise)

Preceding gene: 148652212

Following gene: 148652214

Centisome position: 16.38

GC content: 49.59

Gene sequence:

>1101_bases
ATGGATGTTGAGAGTCTTATGAAAGCAAATTTAGTCGTCCACACCCAAAGCCATGATTATCCCATCATTATCACCAGTCA
GTGTGATATGGCCAAAGAAATTGCGCCTTATATCAAGGGCAAACAAGTGATGATAGTCACCAACACCACAGTTGAAAAGC
TGTATCTAGCAGACTTGGCTGCGGGGCTAAAAGAGGACTTTGAGGTAATGAGTGTGGTGCTACCAGACGGTGAGCAATAC
AAGACTCAGCAGTATATTGATACCATTTATGACGCCTTGATGGACAACCACTGCAGCCGTGACGTGACCTTGGTGGCCTT
AGGCGGTGGGGTGATTGGCGATATGACCGGCTTTGCTGCGGCAAGCTTTATGCGCGGGGTGAACTTTATCCAAATCCCAA
CCACCTTATTGTCTCAAGTGGATTCTAGTGTGGGCGGTAAAACAGGCATTAATCATCCAAAGGGTAAGAACATGATTGGC
GCCTTTTGGCAGCCGCAAATGGTGCTGGCTGATATGCACACCTTGACCACCTTGCCCCAGCGTGAGTTGTCAGCGGGTAT
GGCTGAGGTGATCAAATATGCGCTGATTATGGACGAGACGTTTTTAGATTGGTTAGAGGACAATATGGCCGCTTTAATGG
GGCTTGATAAAGTGGTATTGGCAGAAGCGGTGGCGCGCTGTTGTCAGTACAAGGCCGATATCGTGGCACAAGATGAGCGC
GAAGCGGGTAAGCGGGCACTGCTAAACTTTGGTCATACCTTCGGTCATGTGATTGAGACCCATGAGGGCTATGGTCAGTG
GCTGCACGGCGAGGCAGTGGCTGCCGGAATGGTGCAGGCCGCTCAGCTGTCGCATAAGATGGGCTGGATAAGTGAGGCGC
AGCTGCAGCGTATCTGTGCGGTGTTGATATCGGCCAAGCTGCCCACACAGCCGCCTAGCATAGATACCCAAATTGCCCTT
GACTTAATGCAACACGATAAAAAAGTTAAGTCAGGACAAGTTAGGCTGATTTTGTTAAAATCAGTGGGTGATGCCGTCGT
TACTGCTGACTTTGAGCCTAAGCTGCTTGAAGAGGTGCTTGCAAGCTGCGTACCTAATTAA

Upstream 100 bases:

>100_bases
AATCCTAAGTCTATAAACCCTTAGCGGAAAAGCGATAAGTGAGTCTGTCTTTTAGTTAGTAAGCGTATTGATTGCCCAGC
GTATTGATATTAAGCCTAAA

Downstream 100 bases:

>100_bases
ACAGCAGTTAATGACAGCACAAGGACTCACACAGTATAATAGTGTGCGTTTGATTCATATGATTTAAGTTTAATTAACTA
TTTCAATATCTCTTTATTGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MDVESLMKANLVVHTQSHDYPIIITSQCDMAKEIAPYIKGKQVMIVTNTTVEKLYLADLAAGLKEDFEVMSVVLPDGEQY
KTQQYIDTIYDALMDNHCSRDVTLVALGGGVIGDMTGFAAASFMRGVNFIQIPTTLLSQVDSSVGGKTGINHPKGKNMIG
AFWQPQMVLADMHTLTTLPQRELSAGMAEVIKYALIMDETFLDWLEDNMAALMGLDKVVLAEAVARCCQYKADIVAQDER
EAGKRALLNFGHTFGHVIETHEGYGQWLHGEAVAAGMVQAAQLSHKMGWISEAQLQRICAVLISAKLPTQPPSIDTQIAL
DLMQHDKKVKSGQVRLILLKSVGDAVVTADFEPKLLEEVLASCVPN

Sequences:

>Translated_366_residues
MDVESLMKANLVVHTQSHDYPIIITSQCDMAKEIAPYIKGKQVMIVTNTTVEKLYLADLAAGLKEDFEVMSVVLPDGEQY
KTQQYIDTIYDALMDNHCSRDVTLVALGGGVIGDMTGFAAASFMRGVNFIQIPTTLLSQVDSSVGGKTGINHPKGKNMIG
AFWQPQMVLADMHTLTTLPQRELSAGMAEVIKYALIMDETFLDWLEDNMAALMGLDKVVLAEAVARCCQYKADIVAQDER
EAGKRALLNFGHTFGHVIETHEGYGQWLHGEAVAAGMVQAAQLSHKMGWISEAQLQRICAVLISAKLPTQPPSIDTQIAL
DLMQHDKKVKSGQVRLILLKSVGDAVVTADFEPKLLEEVLASCVPN
>Mature_366_residues
MDVESLMKANLVVHTQSHDYPIIITSQCDMAKEIAPYIKGKQVMIVTNTTVEKLYLADLAAGLKEDFEVMSVVLPDGEQY
KTQQYIDTIYDALMDNHCSRDVTLVALGGGVIGDMTGFAAASFMRGVNFIQIPTTLLSQVDSSVGGKTGINHPKGKNMIG
AFWQPQMVLADMHTLTTLPQRELSAGMAEVIKYALIMDETFLDWLEDNMAALMGLDKVVLAEAVARCCQYKADIVAQDER
EAGKRALLNFGHTFGHVIETHEGYGQWLHGEAVAAGMVQAAQLSHKMGWISEAQLQRICAVLISAKLPTQPPSIDTQIAL
DLMQHDKKVKSGQVRLILLKSVGDAVVTADFEPKLLEEVLASCVPN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=357, Percent_Identity=52.9411764705882, Blast_Score=355, Evalue=3e-99,
Organism=Saccharomyces cerevisiae, GI6320332, Length=324, Percent_Identity=37.962962962963, Blast_Score=215, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40021; Mature: 40021

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVESLMKANLVVHTQSHDYPIIITSQCDMAKEIAPYIKGKQVMIVTNTTVEKLYLADLA
CCHHHHHHCCEEEEECCCCCCEEEECCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHH
AGLKEDFEVMSVVLPDGEQYKTQQYIDTIYDALMDNHCSRDVTLVALGGGVIGDMTGFAA
HHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHH
ASFMRGVNFIQIPTTLLSQVDSSVGGKTGINHPKGKNMIGAFWQPQMVLADMHTLTTLPQ
HHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCH
RELSAGMAEVIKYALIMDETFLDWLEDNMAALMGLDKVVLAEAVARCCQYKADIVAQDER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHH
EAGKRALLNFGHTFGHVIETHEGYGQWLHGEAVAAGMVQAAQLSHKMGWISEAQLQRICA
HHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VLISAKLPTQPPSIDTQIALDLMQHDKKVKSGQVRLILLKSVGDAVVTADFEPKLLEEVL
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCHHHHHHHH
ASCVPN
HHHCCC
>Mature Secondary Structure
MDVESLMKANLVVHTQSHDYPIIITSQCDMAKEIAPYIKGKQVMIVTNTTVEKLYLADLA
CCHHHHHHCCEEEEECCCCCCEEEECCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHH
AGLKEDFEVMSVVLPDGEQYKTQQYIDTIYDALMDNHCSRDVTLVALGGGVIGDMTGFAA
HHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHH
ASFMRGVNFIQIPTTLLSQVDSSVGGKTGINHPKGKNMIGAFWQPQMVLADMHTLTTLPQ
HHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCH
RELSAGMAEVIKYALIMDETFLDWLEDNMAALMGLDKVVLAEAVARCCQYKADIVAQDER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHH
EAGKRALLNFGHTFGHVIETHEGYGQWLHGEAVAAGMVQAAQLSHKMGWISEAQLQRICA
HHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VLISAKLPTQPPSIDTQIALDLMQHDKKVKSGQVRLILLKSVGDAVVTADFEPKLLEEVL
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCHHHHHHHH
ASCVPN
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA