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The map label for this gene is era [H]

Identifier: 148652187

GI number: 148652187

Start: 449984

End: 451003

Strand: Direct

Name: era [H]

Synonym: PsycPRwf_0375

Alternate gene names: 148652187

Gene position: 449984-451003 (Clockwise)

Preceding gene: 148652186

Following gene: 148652188

Centisome position: 15.11

GC content: 44.8

Gene sequence:

>1020_bases
ATGGCAAATGCACCACAAGACAATCAAGACATCACTCCTGAAACAAATTTGGGGACAGATAACTTACTAGACAGCTTTTT
TGGCGACGACAATGCCCTGCCAGAAGATTACCGCGCAGGCTATGTGGCCATCGTGGGCCGTCCAAACGTCGGCAAATCAA
CGCTAATGAACCACATGTTGGGTCAAAAGCTATCTATTACTTCGCGTAAGCCGCAAACAACCCGTCATCGTATTCATGGC
ATCTTATCTCATGAAGATATGCAAGCGGTGTTTGTCGATACCCCAGGTATTCACAGCAATGAAGTTCGCTTGATTAATGA
GCGTATGAATAAAGCTGCTTTTTCTGCGTTGGTGGACGTTGACTTAGTATTGTTCGTGGTAGATGGCGATCAGTGGCGTG
AAGACGACTTATTGACCTTAGAGAAGATTGGTGAGACCGATACGCCTGTGGTACTGGTGATTAACAAGGCGGATACCATT
AAAGATAAAGGCTCAATTCTGCCACTTATTGAAACCTATCATGAAAACTTTGATTTTGCAGATATTGTTCCGGTTTCTGC
CTTAAAGAACCAAAACCTAGAGCGTTTGCAGCAAGTGATCCGCTCACATCTGCCTCAAGGCGCACCCATTTATGACACTG
AGCAAATCACCGATCGCAGTGAGCGCTTTTTGGCCAGCGAAATCATTCGTGAAAAAATCATGCGTCAGTCAGGTGATGAA
GTACCTTATGATTTAACGGTACAAATTGACGAGTTCAAAGATGAGCCGGCGCACATTGATCCAAAAACTGGCCGTAAGCG
CAAAGCGGTAACCTTTATTGATGCCACTATTTTTGTTGAACGTAATGGCCAAAAAGCCATTATCATTGGTGATAAAGGCA
GCCGCATTAAACAAGTAGGTACAGCCGCTCGTGAAGATATGGAAGCTTTGTTTGAGCGCAAAATTATGCTTAACTTGTGG
GTAAAAGTGAAGCAAGGCTGGTCAGATGATGCGCGTGCGCTCAGCAGCTTAGGGTACTAA

Upstream 100 bases:

>100_bases
ATTTTATTTTTTATAAATCTTTTATTTTTTATAAATCAACTCACATTCAAAGCGCCACTAATATAGCGCTTTTATATAAC
GACATCGGATAAACAGATAT

Downstream 100 bases:

>100_bases
TACTGAGCCTGAGCCAAGTGGCGATCATTATCAAGACAGGTACGTTAAGGGTGTGCTTAGTTAGTCAGTTTTTTGAGGAT
GACAGCCATGCGTAATGAAC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MANAPQDNQDITPETNLGTDNLLDSFFGDDNALPEDYRAGYVAIVGRPNVGKSTLMNHMLGQKLSITSRKPQTTRHRIHG
ILSHEDMQAVFVDTPGIHSNEVRLINERMNKAAFSALVDVDLVLFVVDGDQWREDDLLTLEKIGETDTPVVLVINKADTI
KDKGSILPLIETYHENFDFADIVPVSALKNQNLERLQQVIRSHLPQGAPIYDTEQITDRSERFLASEIIREKIMRQSGDE
VPYDLTVQIDEFKDEPAHIDPKTGRKRKAVTFIDATIFVERNGQKAIIIGDKGSRIKQVGTAAREDMEALFERKIMLNLW
VKVKQGWSDDARALSSLGY

Sequences:

>Translated_339_residues
MANAPQDNQDITPETNLGTDNLLDSFFGDDNALPEDYRAGYVAIVGRPNVGKSTLMNHMLGQKLSITSRKPQTTRHRIHG
ILSHEDMQAVFVDTPGIHSNEVRLINERMNKAAFSALVDVDLVLFVVDGDQWREDDLLTLEKIGETDTPVVLVINKADTI
KDKGSILPLIETYHENFDFADIVPVSALKNQNLERLQQVIRSHLPQGAPIYDTEQITDRSERFLASEIIREKIMRQSGDE
VPYDLTVQIDEFKDEPAHIDPKTGRKRKAVTFIDATIFVERNGQKAIIIGDKGSRIKQVGTAAREDMEALFERKIMLNLW
VKVKQGWSDDARALSSLGY
>Mature_338_residues
ANAPQDNQDITPETNLGTDNLLDSFFGDDNALPEDYRAGYVAIVGRPNVGKSTLMNHMLGQKLSITSRKPQTTRHRIHGI
LSHEDMQAVFVDTPGIHSNEVRLINERMNKAAFSALVDVDLVLFVVDGDQWREDDLLTLEKIGETDTPVVLVINKADTIK
DKGSILPLIETYHENFDFADIVPVSALKNQNLERLQQVIRSHLPQGAPIYDTEQITDRSERFLASEIIREKIMRQSGDEV
PYDLTVQIDEFKDEPAHIDPKTGRKRKAVTFIDATIFVERNGQKAIIIGDKGSRIKQVGTAAREDMEALFERKIMLNLWV
KVKQGWSDDARALSSLGY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=344, Percent_Identity=25.2906976744186, Blast_Score=98, Evalue=9e-21,
Organism=Escherichia coli, GI1788919, Length=302, Percent_Identity=50.6622516556291, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI87082120, Length=167, Percent_Identity=30.5389221556886, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24646434, Length=323, Percent_Identity=24.4582043343653, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 38179; Mature: 38048

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANAPQDNQDITPETNLGTDNLLDSFFGDDNALPEDYRAGYVAIVGRPNVGKSTLMNHML
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHH
GQKLSITSRKPQTTRHRIHGILSHEDMQAVFVDTPGIHSNEVRLINERMNKAAFSALVDV
CCCEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEE
DLVLFVVDGDQWREDDLLTLEKIGETDTPVVLVINKADTIKDKGSILPLIETYHENFDFA
EEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCEEHHHHHHHCCCCHH
DIVPVSALKNQNLERLQQVIRSHLPQGAPIYDTEQITDRSERFLASEIIREKIMRQSGDE
HHCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPYDLTVQIDEFKDEPAHIDPKTGRKRKAVTFIDATIFVERNGQKAIIIGDKGSRIKQVG
CCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCEEEEECCCCCHHHHHH
TAAREDMEALFERKIMLNLWVKVKQGWSDDARALSSLGY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
ANAPQDNQDITPETNLGTDNLLDSFFGDDNALPEDYRAGYVAIVGRPNVGKSTLMNHML
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHH
GQKLSITSRKPQTTRHRIHGILSHEDMQAVFVDTPGIHSNEVRLINERMNKAAFSALVDV
CCCEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEE
DLVLFVVDGDQWREDDLLTLEKIGETDTPVVLVINKADTIKDKGSILPLIETYHENFDFA
EEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCEEHHHHHHHCCCCHH
DIVPVSALKNQNLERLQQVIRSHLPQGAPIYDTEQITDRSERFLASEIIREKIMRQSGDE
HHCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPYDLTVQIDEFKDEPAHIDPKTGRKRKAVTFIDATIFVERNGQKAIIIGDKGSRIKQVG
CCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCEEEEECCCCCHHHHHH
TAAREDMEALFERKIMLNLWVKVKQGWSDDARALSSLGY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]