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The map label for this gene is yhcA [H]

Identifier: 148643519

GI number: 148643519

Start: 1482989

End: 1484371

Strand: Reverse

Name: yhcA [H]

Synonym: Msm_1459

Alternate gene names: 148643519

Gene position: 1484371-1482989 (Counterclockwise)

Preceding gene: 148643520

Following gene: 148643514

Centisome position: 80.1

GC content: 33.19

Gene sequence:

>1383_bases
ATGAATGCAAATAAAAAAAGAGATTTTATTGTTATAACTGTAGCCTCTCTTGCCACATTTTACGGCGCATACATGGGAAA
TGTTACGCCTGTTGCACTGCCTAAAATGGCTGAAATTTTTGGATTAAGTAATATAATGCAAAATTGGGTTACAAATATAT
TTTTATTAACAATGGGAGTATTAGCTATTCCTTTAGGAAAGCTCTGCAGCAGATATGGAGTTAAGAAAACATTTATTTAT
TCTGTAATTTTAATGTTAATCGGAAGTATTGGAACTCCCCTATCACACACAATTCCGGAATTATTAATATTCAGAGTAAT
TCAGGGAATCGGAGGTGCCGGTCTTTGTGTAGATTCAATGTTAATAATTGCTGAGGCAATAAGTCCTGAAAAAAGAGGTC
AGGCACTGGGAATAACTGTAAGCTGCACATATATCGGAATTGCACTGGCACCAGTACTTGGAGGCAGTCTAACCTATAAT
TTCGGCTGGGAATCCATATTCTGGGTAATGATTCCATTTATATTATTAAACCTAATATTACTTTTTACAATAAAAGAGGA
ATGGTTCAAATACCAAAATGAAAAATTCGACTTGAAAGGTTCTATAGTCTTTGCAATTGGAATCTTATTATTGATTTACG
GATTTTCAATATTTAATACAACAATAGGATTCATAATAACTGTTGCTGGAGTGCTTTTACTGATTTTATTTGGTAAAATT
GAGTTAAACTCCAAATATCCTGCATATGACATAAAATTATATAAAAATAAGAAATTTTTATCAAGCAATATAGCCAGTAT
ATTAAGTTACATAGCTACCTTTGTAGTAACTACAATTGTCAATTACAATTTCCAGTATGTTCGCGGTTTTGATTCACAGC
TTTCAGGACTGATTTTAATTACATTCCCATTATTAATGGCTATTGTAGCTCCAGCAGCCGGAAAATTATCTGATAGAATT
GATCCTCAAAAAATTGCAACAATCGGAATGATAATTGTAACTGTCGGTTTAATCCTGCTTGTACCTCTTGATAAAGACAC
ATCAATTGTAATTGTACTTGTATCACTTGCATTGCAGGGTATAGGCTACGGATTATTCGCAAGTCCAAACATCAACACTA
TAATGAGCAGTGTTCCTCCAAAAGATACTCCAATGGCATCAAGTGCAGTAGCTACAATGAGAATACTTGGTCAAACATTA
AGTACTGGAATATTAACTGTGATTTTTGCAATAATGATGGGAAATGTAATAATTCAGCCATCTAACTATCCTCAGCTTAT
TTCCTGTTCCCAAATAACATTACTGATTATAACCGTAATCAGTGCTCTTTGTTTTATTGTCTGCCATATAGGCTACAAAT
CCAAGGACAAACTGTATTTTTAA

Upstream 100 bases:

>100_bases
AATGAATTTATGATTATAACAGATAAATCAAATAGAAAATTGCATATTACTTAAAAAATACAAACTACATTATAATAAAT
AAAAAAGAGAGTTGTTTTTT

Downstream 100 bases:

>100_bases
ATTGGAAAAAAGAGTTTAAAAGATAGCTGTTTATAACAAAACAGCTATTAATTTTATTTTAAATTAATGTGTTATGTTCA
CACATCGGATCTTTCATGAT

Product: multidrug efflux permease, AraJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MNANKKRDFIVITVASLATFYGAYMGNVTPVALPKMAEIFGLSNIMQNWVTNIFLLTMGVLAIPLGKLCSRYGVKKTFIY
SVILMLIGSIGTPLSHTIPELLIFRVIQGIGGAGLCVDSMLIIAEAISPEKRGQALGITVSCTYIGIALAPVLGGSLTYN
FGWESIFWVMIPFILLNLILLFTIKEEWFKYQNEKFDLKGSIVFAIGILLLIYGFSIFNTTIGFIITVAGVLLLILFGKI
ELNSKYPAYDIKLYKNKKFLSSNIASILSYIATFVVTTIVNYNFQYVRGFDSQLSGLILITFPLLMAIVAPAAGKLSDRI
DPQKIATIGMIIVTVGLILLVPLDKDTSIVIVLVSLALQGIGYGLFASPNINTIMSSVPPKDTPMASSAVATMRILGQTL
STGILTVIFAIMMGNVIIQPSNYPQLISCSQITLLIITVISALCFIVCHIGYKSKDKLYF

Sequences:

>Translated_460_residues
MNANKKRDFIVITVASLATFYGAYMGNVTPVALPKMAEIFGLSNIMQNWVTNIFLLTMGVLAIPLGKLCSRYGVKKTFIY
SVILMLIGSIGTPLSHTIPELLIFRVIQGIGGAGLCVDSMLIIAEAISPEKRGQALGITVSCTYIGIALAPVLGGSLTYN
FGWESIFWVMIPFILLNLILLFTIKEEWFKYQNEKFDLKGSIVFAIGILLLIYGFSIFNTTIGFIITVAGVLLLILFGKI
ELNSKYPAYDIKLYKNKKFLSSNIASILSYIATFVVTTIVNYNFQYVRGFDSQLSGLILITFPLLMAIVAPAAGKLSDRI
DPQKIATIGMIIVTVGLILLVPLDKDTSIVIVLVSLALQGIGYGLFASPNINTIMSSVPPKDTPMASSAVATMRILGQTL
STGILTVIFAIMMGNVIIQPSNYPQLISCSQITLLIITVISALCFIVCHIGYKSKDKLYF
>Mature_460_residues
MNANKKRDFIVITVASLATFYGAYMGNVTPVALPKMAEIFGLSNIMQNWVTNIFLLTMGVLAIPLGKLCSRYGVKKTFIY
SVILMLIGSIGTPLSHTIPELLIFRVIQGIGGAGLCVDSMLIIAEAISPEKRGQALGITVSCTYIGIALAPVLGGSLTYN
FGWESIFWVMIPFILLNLILLFTIKEEWFKYQNEKFDLKGSIVFAIGILLLIYGFSIFNTTIGFIITVAGVLLLILFGKI
ELNSKYPAYDIKLYKNKKFLSSNIASILSYIATFVVTTIVNYNFQYVRGFDSQLSGLILITFPLLMAIVAPAAGKLSDRI
DPQKIATIGMIIVTVGLILLVPLDKDTSIVIVLVSLALQGIGYGLFASPNINTIMSSVPPKDTPMASSAVATMRILGQTL
STGILTVIFAIMMGNVIIQPSNYPQLISCSQITLLIITVISALCFIVCHIGYKSKDKLYF

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=381, Percent_Identity=26.246719160105, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789042, Length=415, Percent_Identity=25.5421686746988, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790195, Length=310, Percent_Identity=28.3870967741935, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788710, Length=406, Percent_Identity=25.615763546798, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081723, Length=158, Percent_Identity=28.4810126582279, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788392, Length=180, Percent_Identity=30.5555555555556, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790146, Length=158, Percent_Identity=31.6455696202532, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50133; Mature: 50133

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNANKKRDFIVITVASLATFYGAYMGNVTPVALPKMAEIFGLSNIMQNWVTNIFLLTMGV
CCCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIPLGKLCSRYGVKKTFIYSVILMLIGSIGTPLSHTIPELLIFRVIQGIGGAGLCVDSM
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
LIIAEAISPEKRGQALGITVSCTYIGIALAPVLGGSLTYNFGWESIFWVMIPFILLNLIL
HHHHHHCCHHHCCCEEEEEEEHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHH
LFTIKEEWFKYQNEKFDLKGSIVFAIGILLLIYGFSIFNTTIGFIITVAGVLLLILFGKI
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ELNSKYPAYDIKLYKNKKFLSSNIASILSYIATFVVTTIVNYNFQYVRGFDSQLSGLILI
EECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHCCHHHH
TFPLLMAIVAPAAGKLSDRIDPQKIATIGMIIVTVGLILLVPLDKDTSIVIVLVSLALQG
HHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHH
IGYGLFASPNINTIMSSVPPKDTPMASSAVATMRILGQTLSTGILTVIFAIMMGNVIIQP
CCCCEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECC
SNYPQLISCSQITLLIITVISALCFIVCHIGYKSKDKLYF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNANKKRDFIVITVASLATFYGAYMGNVTPVALPKMAEIFGLSNIMQNWVTNIFLLTMGV
CCCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIPLGKLCSRYGVKKTFIYSVILMLIGSIGTPLSHTIPELLIFRVIQGIGGAGLCVDSM
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
LIIAEAISPEKRGQALGITVSCTYIGIALAPVLGGSLTYNFGWESIFWVMIPFILLNLIL
HHHHHHCCHHHCCCEEEEEEEHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHH
LFTIKEEWFKYQNEKFDLKGSIVFAIGILLLIYGFSIFNTTIGFIITVAGVLLLILFGKI
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ELNSKYPAYDIKLYKNKKFLSSNIASILSYIATFVVTTIVNYNFQYVRGFDSQLSGLILI
EECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHCCHHHH
TFPLLMAIVAPAAGKLSDRIDPQKIATIGMIIVTVGLILLVPLDKDTSIVIVLVSLALQG
HHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHH
IGYGLFASPNINTIMSSVPPKDTPMASSAVATMRILGQTLSTGILTVIFAIMMGNVIIQP
CCCCEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECC
SNYPQLISCSQITLLIITVISALCFIVCHIGYKSKDKLYF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8969498 [H]