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The map label for this gene is apt1 [H]

Identifier: 148643419

GI number: 148643419

Start: 1381954

End: 1382523

Strand: Reverse

Name: apt1 [H]

Synonym: Msm_1359

Alternate gene names: 148643419

Gene position: 1382523-1381954 (Counterclockwise)

Preceding gene: 148643427

Following gene: 148643418

Centisome position: 74.6

GC content: 29.3

Gene sequence:

>570_bases
ATGTTAGAAGAAGTTAAAAAATCTTTAGAAGCTTCTCCTATTGTTAAAAAAGGAGATTATAATTATTTTGTTAATCCTAT
AAGTGATGGAGTTCCAACTATGAAACCTTCAATGCTTCGTGAATTAGCAAATGTTGTAAAAGAACATGTTGATATGGATA
TTGATAAAATAGTCGCTATTGAAGCTATGGGAATACATTTAGCTACAGCTTTATCCTTAGCTACCGACATCCCATTTGTA
ATTATCCGTAAAAGACAATATGGACTTGAAGGAGAAAAAGAAATAAGTCAAAAAACAGGCTACGGGTCTTCTAAATTATA
TATAAATGATTTAAAAGAAGGAGAAAAAATCCTTTTAATAGATGATGTTGTAAGTACTGGAGGAACATTAATTTCAACTT
TAAATGCACTAAAAGAATTAAATATTGACATAAAAGCTGCAGTAGCTGTTATTGAAAAAGGAGAAGGCAAAAAATTAGTT
GAAAAAGAAACTGGCATTCCAATATTTTCAGTTGTAAAATTAGATGTAATTGACGGCAAAGTAGTTATCGAAAAAACCAT
TGAAGATTAA

Upstream 100 bases:

>100_bases
ATCACACGATTAAAATTATTCTTTAAGAAAAATTTATATTAATATTTATATTAAATATATATTATATTTGATTTAATTTT
TAAATTTTTGTGTGAGATAA

Downstream 100 bases:

>100_bases
AATGTCAATGTATAACATGGACTTAGACAAAGTCATAAGAAAGATTAATAAAAAAGGAGCTAGAACTGTAGGTCTTCAAT
TTCCGGAAGGTCTTAAAATG

Product: adenine phosphoribosyltransferase

Products: NA

Alternate protein names: APRT 1 [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MLEEVKKSLEASPIVKKGDYNYFVNPISDGVPTMKPSMLRELANVVKEHVDMDIDKIVAIEAMGIHLATALSLATDIPFV
IIRKRQYGLEGEKEISQKTGYGSSKLYINDLKEGEKILLIDDVVSTGGTLISTLNALKELNIDIKAAVAVIEKGEGKKLV
EKETGIPIFSVVKLDVIDGKVVIEKTIED

Sequences:

>Translated_189_residues
MLEEVKKSLEASPIVKKGDYNYFVNPISDGVPTMKPSMLRELANVVKEHVDMDIDKIVAIEAMGIHLATALSLATDIPFV
IIRKRQYGLEGEKEISQKTGYGSSKLYINDLKEGEKILLIDDVVSTGGTLISTLNALKELNIDIKAAVAVIEKGEGKKLV
EKETGIPIFSVVKLDVIDGKVVIEKTIED
>Mature_189_residues
MLEEVKKSLEASPIVKKGDYNYFVNPISDGVPTMKPSMLRELANVVKEHVDMDIDKIVAIEAMGIHLATALSLATDIPFV
IIRKRQYGLEGEKEISQKTGYGSSKLYINDLKEGEKILLIDDVVSTGGTLISTLNALKELNIDIKAAVAVIEKGEGKKLV
EKETGIPIFSVVKLDVIDGKVVIEKTIED

Specific function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005764
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.7 [H]

Molecular weight: Translated: 20696; Mature: 20696

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEEVKKSLEASPIVKKGDYNYFVNPISDGVPTMKPSMLRELANVVKEHVDMDIDKIVAI
CHHHHHHHHCCCCCEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHEEHH
EAMGIHLATALSLATDIPFVIIRKRQYGLEGEKEISQKTGYGSSKLYINDLKEGEKILLI
HHHHHHHHHHHHHHHCCCEEEEECHHCCCCCHHHHHHHCCCCCCEEEEEECCCCCEEEEE
DDVVSTGGTLISTLNALKELNIDIKAAVAVIEKGEGKKLVEKETGIPIFSVVKLDVIDGK
ECHHHCCHHHHHHHHHHHHCCCCHHHHEEEEECCCCCCHHHHHCCCCEEEEEEEEEECCE
VVIEKTIED
EEEEECCCC
>Mature Secondary Structure
MLEEVKKSLEASPIVKKGDYNYFVNPISDGVPTMKPSMLRELANVVKEHVDMDIDKIVAI
CHHHHHHHHCCCCCEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHEEHH
EAMGIHLATALSLATDIPFVIIRKRQYGLEGEKEISQKTGYGSSKLYINDLKEGEKILLI
HHHHHHHHHHHHHHHCCCEEEEECHHCCCCCHHHHHHHCCCCCCEEEEEECCCCCEEEEE
DDVVSTGGTLISTLNALKELNIDIKAAVAVIEKGEGKKLVEKETGIPIFSVVKLDVIDGK
ECHHHCCHHHHHHHHHHHHCCCCHHHHEEEEECCCCCCHHHHHCCCCEEEEEEEEEECCE
VVIEKTIED
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA