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The map label for this gene is cdc6-1 [H]

Identifier: 148643324

GI number: 148643324

Start: 1268479

End: 1269630

Strand: Reverse

Name: cdc6-1 [H]

Synonym: Msm_1264

Alternate gene names: 148643324

Gene position: 1269630-1268479 (Counterclockwise)

Preceding gene: 148643325

Following gene: 148643320

Centisome position: 68.51

GC content: 30.99

Gene sequence:

>1152_bases
ATGGCAAATATTTTTGATGACTTGGAGGTAGGAAAATCAGTTTTTAAAGATAAACAACCTTTAGATCATAGGTTTTTACC
TGAAAATTTACCTCACAGGAAAGAACAGATAACACAAATAGCTAAATATTGGATTGAAGCATTAAATAATGTTACTCCAT
CTGATATTACTATTTACGGAAAAACAGGAACTGGAAAAACAGCAGCAGCAAAATTTGCTCGTGAACAGTTAAATGAAGCA
GCATCTAATAAAAATGTTTTCATAAAAGTTGAATATATTCGATGTACTGACTACACAACAGAATATCAGGTTATTGCACA
ACTGTGTCAAAAGCTTGGAAGAAATGTTCCTCACAGAGGATGGACAAAAGGAGAAGTTATTAATACTTTCAGGGACATTT
TCAGAAGAAATGCTTATGGAAAAAAACTAATTTTAATTGTTATTTTAGATGAAATCGACATATTGCTCAGCAAAGATGGT
GATGGAATTTTATATACATTAACAAGAACTGATAATGTATCCATATTGTCCATTAGTAATTATGTTGAATTTAAACAGTT
TATCACACCTAGAGTAATGAGTAGTTTAAGGGATAAGGAAATTGTTTTTCCGCCTTATGGTGCTGATCAATTGGCTGATA
TTTTAAGTGAAAGGGCTAGTTTGTCATTTAAAGAAGATACAATTGAAAGTGATGTTATACCATTATGTTCAGCTATGGCA
GCTAAAGAAGAAGGAGATGCAAGATATGCTCTGGATTTACTTAGAACTGCTGGGGAAATAGCTGATGAAGAAGAATCTGA
TAAAATCATTGGCGATTATGTAAGAAGGGCAAAAGATAGAATTGAGCATAATAAAATTACTGATGTTATTTTAACTCTAC
CAACTCAACAGCAAAGAGTTTTAGACGCTATTTTAAGACTTACTCAGAATAATGAAGAAATAACATCAGGTAAATTATAC
GATACCTACAAAGAAGTATCAAAAGGAGATTCTGTAACATACAGAAGAATTTTTGATTTTATAAATGAACTTGAAATGTT
AGGTATTATTTCAACCAATACTATATCACGTGGACGTGGAAAAGGAAGAACTAATATTATAACACTTCAATGCGATACTG
ATTTACTTGAAAAAACACTTTATTCAATATGA

Upstream 100 bases:

>100_bases
TATTTAACACTGTTTTCATATATTATCACTGGAAATAATACTTATGATTTTTTCATGTTTTTAAGATTATTTTTTTATTA
CTTTTTAAAATGGTGAACAT

Downstream 100 bases:

>100_bases
TTCCATTTAGGATTGTTTTTTATTAAAGTTTTTAAAATGGCCATTCTAACTGGAACAGCATTAAATGCTTGATTGAAATA
TTTGTTATGTTTGGTGTTAT

Product: cell division control protein 6, Cdc6

Products: NA

Alternate protein names: CDC6 homolog 1 [H]

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MANIFDDLEVGKSVFKDKQPLDHRFLPENLPHRKEQITQIAKYWIEALNNVTPSDITIYGKTGTGKTAAAKFAREQLNEA
ASNKNVFIKVEYIRCTDYTTEYQVIAQLCQKLGRNVPHRGWTKGEVINTFRDIFRRNAYGKKLILIVILDEIDILLSKDG
DGILYTLTRTDNVSILSISNYVEFKQFITPRVMSSLRDKEIVFPPYGADQLADILSERASLSFKEDTIESDVIPLCSAMA
AKEEGDARYALDLLRTAGEIADEEESDKIIGDYVRRAKDRIEHNKITDVILTLPTQQQRVLDAILRLTQNNEEITSGKLY
DTYKEVSKGDSVTYRRIFDFINELEMLGIISTNTISRGRGKGRTNIITLQCDTDLLEKTLYSI

Sequences:

>Translated_383_residues
MANIFDDLEVGKSVFKDKQPLDHRFLPENLPHRKEQITQIAKYWIEALNNVTPSDITIYGKTGTGKTAAAKFAREQLNEA
ASNKNVFIKVEYIRCTDYTTEYQVIAQLCQKLGRNVPHRGWTKGEVINTFRDIFRRNAYGKKLILIVILDEIDILLSKDG
DGILYTLTRTDNVSILSISNYVEFKQFITPRVMSSLRDKEIVFPPYGADQLADILSERASLSFKEDTIESDVIPLCSAMA
AKEEGDARYALDLLRTAGEIADEEESDKIIGDYVRRAKDRIEHNKITDVILTLPTQQQRVLDAILRLTQNNEEITSGKLY
DTYKEVSKGDSVTYRRIFDFINELEMLGIISTNTISRGRGKGRTNIITLQCDTDLLEKTLYSI
>Mature_382_residues
ANIFDDLEVGKSVFKDKQPLDHRFLPENLPHRKEQITQIAKYWIEALNNVTPSDITIYGKTGTGKTAAAKFAREQLNEAA
SNKNVFIKVEYIRCTDYTTEYQVIAQLCQKLGRNVPHRGWTKGEVINTFRDIFRRNAYGKKLILIVILDEIDILLSKDGD
GILYTLTRTDNVSILSISNYVEFKQFITPRVMSSLRDKEIVFPPYGADQLADILSERASLSFKEDTIESDVIPLCSAMAA
KEEGDARYALDLLRTAGEIADEEESDKIIGDYVRRAKDRIEHNKITDVILTLPTQQQRVLDAILRLTQNNEEITSGKLYD
TYKEVSKGDSVTYRRIFDFINELEMLGIISTNTISRGRGKGRTNIITLQCDTDLLEKTLYSI

Specific function: Might be involved in the initiation of DNA replication [H]

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family [H]

Homologues:

Organism=Homo sapiens, GI4502703, Length=341, Percent_Identity=23.7536656891496, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555708, Length=321, Percent_Identity=25.8566978193146, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355681, Length=339, Percent_Identity=23.3038348082596, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17137456, Length=248, Percent_Identity=25.4032258064516, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00004 AAA; PF09079 Cdc6_C [H]

EC number: NA

Molecular weight: Translated: 43611; Mature: 43480

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIFDDLEVGKSVFKDKQPLDHRFLPENLPHRKEQITQIAKYWIEALNNVTPSDITIYG
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
KTGTGKTAAAKFAREQLNEAASNKNVFIKVEYIRCTDYTTEYQVIAQLCQKLGRNVPHRG
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCC
WTKGEVINTFRDIFRRNAYGKKLILIVILDEIDILLSKDGDGILYTLTRTDNVSILSISN
CCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCCEEEEEEEECCCEEEEEEHH
YVEFKQFITPRVMSSLRDKEIVFPPYGADQLADILSERASLSFKEDTIESDVIPLCSAMA
HHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AKEEGDARYALDLLRTAGEIADEEESDKIIGDYVRRAKDRIEHNKITDVILTLPTQQQRV
HCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHH
LDAILRLTQNNEEITSGKLYDTYKEVSKGDSVTYRRIFDFINELEMLGIISTNTISRGRG
HHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCC
KGRTNIITLQCDTDLLEKTLYSI
CCCCEEEEEEECHHHHHHHHHCC
>Mature Secondary Structure 
ANIFDDLEVGKSVFKDKQPLDHRFLPENLPHRKEQITQIAKYWIEALNNVTPSDITIYG
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
KTGTGKTAAAKFAREQLNEAASNKNVFIKVEYIRCTDYTTEYQVIAQLCQKLGRNVPHRG
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCC
WTKGEVINTFRDIFRRNAYGKKLILIVILDEIDILLSKDGDGILYTLTRTDNVSILSISN
CCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCCEEEEEEEECCCEEEEEEHH
YVEFKQFITPRVMSSLRDKEIVFPPYGADQLADILSERASLSFKEDTIESDVIPLCSAMA
HHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AKEEGDARYALDLLRTAGEIADEEESDKIIGDYVRRAKDRIEHNKITDVILTLPTQQQRV
HCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHH
LDAILRLTQNNEEITSGKLYDTYKEVSKGDSVTYRRIFDFINELEMLGIISTNTISRGRG
HHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCC
KGRTNIITLQCDTDLLEKTLYSI
CCCCEEEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463; 11514535 [H]