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The map label for this gene is yxaL [H]

Identifier: 148643307

GI number: 148643307

Start: 1251536

End: 1252771

Strand: Reverse

Name: yxaL [H]

Synonym: Msm_1247

Alternate gene names: 148643307

Gene position: 1252771-1251536 (Counterclockwise)

Preceding gene: 148643308

Following gene: 148643306

Centisome position: 67.6

GC content: 30.58

Gene sequence:

>1236_bases
ATGTCTAAATATAATAAATTATTAATCGGATTTATAATCTGTATATTATGTATCAGCCCGATAGCTGGTGCAAATATTGA
TTGGAACACATTTCAAAGTAATTTAAATCATACAGGATATGTTGATGATAATTCTGACTTTGTTACAAATTTATGGTCAT
TTAACATGGAATCACCGGTTATAGGCTCACCTGCAATCTATGGGGACTTTTTATATGTTGTTTCACAGGAAGGTATTTTA
AAAGTAATTGACATGGAAAACGGAACTGAAGACTGGTCATTTAATTTAAAAGGAGACAGTAATGCAACACCTGTAGTAAG
TAACAATACAGTATTTGTAGGAAATAATCAAAGTTTTAAAGCTATAGATATTGAATCACAAGATATTTTATGGAAATATA
ATACTTCTGATGAATCTATTCAGGGGGCAGCTTATGTAGATAATGATACTGTCTATGTAGGTTGTGATAATGGGCATATT
TATGGATTTGACATAGCTGACGGTAATAAAACTTTTGAAGCAGATTTAGGTAATGATGAAATAGTGTCTTCTCCAATTGT
TGTTAACGGATCACTTTATGTTGGTTCAACTAACGGTAATGTTTATTGCATAAATTTAAATAACACAAATATAACCTGGC
AATATGCTACAGGAGATGCAGTTTACTCTTCTCCAGCATATGCAGATGGTAAAATCATAATTGGGTCTGATGATGATTCA
CTTTATGCTTTAAATGAAACAAATGGAGATTTATGCTGGGATTATGATTTAAACAATAAAGTTAAATCTTCTCCATGTAT
TGATGAGTATAATAACAATGTATACATAGGTTCTGATGAAGGTAATTTAACCTGTCTTGATTTAAGAGACGGAACTTTTA
AATGGAGTCATGCTACTGGAGCTCCGGTTCAATCAACTCCAGCAATAAAAGAAGAGTTAATTGCATTTGGTTCTAATGAT
GGAACAGGTTATGTTTTAAATAAATACACTGGTGAAGAGGAATTTACTTACAATCCAGGAACCATATTATTTAATTCAGA
AATAACTTCTTCTCCTGTAATTAATGGAAATAGTTTATTCTTTGCAGATCATAGCGGACATGTATATTCATTAAACATTG
ATAAAAGTGAAGTACCTGCTTGTGAATATTTATATTATACATTAGCTGTTTTGGTTGTAATCTTAGTTGTGGTTGTTGTT
GTAGTTAAAACTATAAAAAAACATAATAGAAGATAA

Upstream 100 bases:

>100_bases
CGATGTATGGTTAGATTTAGCTATACTTTTAGGATTCACTGCACTGTTCTTTATCATTGGAGTCAAAAGATTTAATAGAG
ATATTTAAGGAGGCTAAAAG

Downstream 100 bases:

>100_bases
ACTTTAAATATCTAAAAAGAAGTAATTACTATTACATTAAAATGGGAAGTTTTAATTATGTATGGTAAAAATATCGAGAC
ACTAAAAAAGGAAAATATGA

Product: serine/threonine protein kinase related protein (PQQ-binding)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSKYNKLLIGFIICILCISPIAGANIDWNTFQSNLNHTGYVDDNSDFVTNLWSFNMESPVIGSPAIYGDFLYVVSQEGIL
KVIDMENGTEDWSFNLKGDSNATPVVSNNTVFVGNNQSFKAIDIESQDILWKYNTSDESIQGAAYVDNDTVYVGCDNGHI
YGFDIADGNKTFEADLGNDEIVSSPIVVNGSLYVGSTNGNVYCINLNNTNITWQYATGDAVYSSPAYADGKIIIGSDDDS
LYALNETNGDLCWDYDLNNKVKSSPCIDEYNNNVYIGSDEGNLTCLDLRDGTFKWSHATGAPVQSTPAIKEELIAFGSND
GTGYVLNKYTGEEEFTYNPGTILFNSEITSSPVINGNSLFFADHSGHVYSLNIDKSEVPACEYLYYTLAVLVVILVVVVV
VVKTIKKHNRR

Sequences:

>Translated_411_residues
MSKYNKLLIGFIICILCISPIAGANIDWNTFQSNLNHTGYVDDNSDFVTNLWSFNMESPVIGSPAIYGDFLYVVSQEGIL
KVIDMENGTEDWSFNLKGDSNATPVVSNNTVFVGNNQSFKAIDIESQDILWKYNTSDESIQGAAYVDNDTVYVGCDNGHI
YGFDIADGNKTFEADLGNDEIVSSPIVVNGSLYVGSTNGNVYCINLNNTNITWQYATGDAVYSSPAYADGKIIIGSDDDS
LYALNETNGDLCWDYDLNNKVKSSPCIDEYNNNVYIGSDEGNLTCLDLRDGTFKWSHATGAPVQSTPAIKEELIAFGSND
GTGYVLNKYTGEEEFTYNPGTILFNSEITSSPVINGNSLFFADHSGHVYSLNIDKSEVPACEYLYYTLAVLVVILVVVVV
VVKTIKKHNRR
>Mature_410_residues
SKYNKLLIGFIICILCISPIAGANIDWNTFQSNLNHTGYVDDNSDFVTNLWSFNMESPVIGSPAIYGDFLYVVSQEGILK
VIDMENGTEDWSFNLKGDSNATPVVSNNTVFVGNNQSFKAIDIESQDILWKYNTSDESIQGAAYVDNDTVYVGCDNGHIY
GFDIADGNKTFEADLGNDEIVSSPIVVNGSLYVGSTNGNVYCINLNNTNITWQYATGDAVYSSPAYADGKIIIGSDDDSL
YALNETNGDLCWDYDLNNKVKSSPCIDEYNNNVYIGSDEGNLTCLDLRDGTFKWSHATGAPVQSTPAIKEELIAFGSNDG
TGYVLNKYTGEEEFTYNPGTILFNSEITSSPVINGNSLFFADHSGHVYSLNIDKSEVPACEYLYYTLAVLVVILVVVVVV
VKTIKKHNRR

Specific function: Increases the processivity of the pcrA helicase, but does not bind to DNA [H]

COG id: COG1520

COG function: function code S; FOG: WD40-like repeat

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI45580730, Length=318, Percent_Identity=25.1572327044025, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1788859, Length=313, Percent_Identity=23.3226837060703, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047 [H]

Pfam domain/function: PF01011 PQQ [H]

EC number: NA

Molecular weight: Translated: 45124; Mature: 44993

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYNKLLIGFIICILCISPIAGANIDWNTFQSNLNHTGYVDDNSDFVTNLWSFNMESPV
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEECCCCCCEEEEEECCCCCCC
IGSPAIYGDFLYVVSQEGILKVIDMENGTEDWSFNLKGDSNATPVVSNNTVFVGNNQSFK
CCCCCCEEEEEEEEECCCEEEEEECCCCCCCEEEEECCCCCCCCEEECCEEEECCCCCEE
AIDIESQDILWKYNTSDESIQGAAYVDNDTVYVGCDNGHIYGFDIADGNKTFEADLGNDE
EEEECCCEEEEEECCCCCCCCCEEEECCCEEEEECCCCEEEEEEECCCCEEEEECCCCCC
IVSSPIVVNGSLYVGSTNGNVYCINLNNTNITWQYATGDAVYSSPAYADGKIIIGSDDDS
EECCCEEEECEEEEECCCCCEEEEEECCCEEEEEEECCCEEECCCCCCCCEEEEECCCCC
LYALNETNGDLCWDYDLNNKVKSSPCIDEYNNNVYIGSDEGNLTCLDLRDGTFKWSHATG
EEEEECCCCCEEEEECCCCCCCCCCCHHHCCCCEEEECCCCCEEEEEECCCEEEECCCCC
APVQSTPAIKEELIAFGSNDGTGYVLNKYTGEEEFTYNPGTILFNSEITSSPVINGNSLF
CCCCCCCHHHHHHHEECCCCCCEEEEEEECCCCCEEECCCEEEECCCCCCCCEECCCEEE
FADHSGHVYSLNIDKSEVPACEYLYYTLAVLVVILVVVVVVVKTIKKHNRR
EEECCCCEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKYNKLLIGFIICILCISPIAGANIDWNTFQSNLNHTGYVDDNSDFVTNLWSFNMESPV
CHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEECCCCCCEEEEEECCCCCCC
IGSPAIYGDFLYVVSQEGILKVIDMENGTEDWSFNLKGDSNATPVVSNNTVFVGNNQSFK
CCCCCCEEEEEEEEECCCEEEEEECCCCCCCEEEEECCCCCCCCEEECCEEEECCCCCEE
AIDIESQDILWKYNTSDESIQGAAYVDNDTVYVGCDNGHIYGFDIADGNKTFEADLGNDE
EEEECCCEEEEEECCCCCCCCCEEEECCCEEEEECCCCEEEEEEECCCCEEEEECCCCCC
IVSSPIVVNGSLYVGSTNGNVYCINLNNTNITWQYATGDAVYSSPAYADGKIIIGSDDDS
EECCCEEEECEEEEECCCCCEEEEEECCCEEEEEEECCCEEECCCCCCCCEEEEECCCCC
LYALNETNGDLCWDYDLNNKVKSSPCIDEYNNNVYIGSDEGNLTCLDLRDGTFKWSHATG
EEEEECCCCCEEEEECCCCCCCCCCCHHHCCCCEEEECCCCCEEEEEECCCEEEECCCCC
APVQSTPAIKEELIAFGSNDGTGYVLNKYTGEEEFTYNPGTILFNSEITSSPVINGNSLF
CCCCCCCHHHHHHHEECCCCCCEEEEEEECCCCCEEECCCEEEECCCCCCCCEECCCEEE
FADHSGHVYSLNIDKSEVPACEYLYYTLAVLVVILVVVVVVVKTIKKHNRR
EEECCCCEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 10568751; 10658653 [H]