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The map label for this gene is fae-hps [H]

Identifier: 148643273

GI number: 148643273

Start: 1212825

End: 1214051

Strand: Reverse

Name: fae-hps [H]

Synonym: Msm_1213

Alternate gene names: 148643273

Gene position: 1214051-1212825 (Counterclockwise)

Preceding gene: 148643274

Following gene: 148643272

Centisome position: 65.51

GC content: 36.02

Gene sequence:

>1227_bases
ATGTACAATATAGGAGAAGCTCTTATTGGTGATGGAAACGAGTTAGCTCATATTGATTTAATAATCGGTGAAAAAGAAGG
ACCTGTAGGTCAAGCTTTTGCAAACGGATTATCAAATTTATCTGTGGGCCACACTCCATTAACCACTGTAATTAGACCAA
ATTTAATGACTAAACCAGCAACTTTAATCATTCCTAAAGTTACTGTTGGAGATTTAGACGATGCTGCTAAAGTATTTGGA
CCTGCACAAACTGCTGTTGGTAGGGCAGTAGCTGATGCAGTAGAAGAAGGATACATTCCAAAAGACATCGTTGAGGACAT
CGTAATTAATGTAAGTGTATTTATTGACCCTGCTGCAAAAAATTATAGGAAAATATATCAATACAACTATGGAGCAACTA
AATTAGCTATTAGAAGGGCTATGGAAGGTTACCCATCTATTGACAAAGTACTTGCAGAAAAAGATCGTGGAACTCACCCA
ATTATGGGCTTCAGAGTACAAAAACTTTGGTCCCCACCATATTTACAAGTTGCACTTGATTTAGACAACTTAGACGCTAT
GGAAAGAATCATCAACGATTTGCCTGATAAAGAAAGAGTTCTTATTGAAGCGGGAACTCCACTTGTTAAAAAATTCGGTG
TCGGTGTTGTTGGAAAAATTAGGGAATTACGTCCAAGTGCATTCATTATAGCTGACCTAAAAACTTTAGATGTTGGTAGA
GTAGAAATAAAAATGGCTGCAGATGAAACAGCAGATGCAGTAGCTATTTCTGGTCTTGGAACTATCGAATCTATTAAGAA
AGCTATTCATGAAACTCAAAAACAAGGTATTTATTCAATCCTTGATATGATGAATGTGGCTGACTTTGAAGAAAAATTAT
CTGCTCTTCCAGATGACTTAAAACCGGATATAGTTTTATTACACAGAAATGTGGATTTAGAAACTTACAAAGCTGAAAAA
GGTGAAGATACCAGTGAAATGACTGAATGGGGTAATATTAAATCCATTAAAAAACTCATTGGTGACGGTTTAGTTGCAGT
AGCTGGAGGAATTACTCCTAATAAAGTAGAGGAAGCTACTTCAAAAGGTGCAGATATTATTATTGCAGGTAGATACATTA
TTGGTTCTAGAGATGTAAGAAGAGCTGCTGAAGACTTCTTAGCACATTTCCCACAAGATCCAGATAGTATGAGACTTGCA
CTTGATGAAGACGAACAAGTAAATTAA

Upstream 100 bases:

>100_bases
TTAGAGCAATATTATCAGTAACTTGTTTTTTAGTAGTTAGCTTTATTTAATTAAAAAAATATAATTATATATTGTATATA
ATATACGGAGGAACTATTTA

Downstream 100 bases:

>100_bases
ATCTTTTGATTTAATTTATTCTATTTTTTTTTAAAAAAGGAGATTATAATATGGGATTTTGTAATTCTTGCGGCAGGCCA
ATTGTAAAAGCAGATTATGG

Product: bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase

Products: NA

Alternate protein names: Formaldehyde-activating enzyme; Fae; 3-hexulose-6-phosphate synthase; HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MYNIGEALIGDGNELAHIDLIIGEKEGPVGQAFANGLSNLSVGHTPLTTVIRPNLMTKPATLIIPKVTVGDLDDAAKVFG
PAQTAVGRAVADAVEEGYIPKDIVEDIVINVSVFIDPAAKNYRKIYQYNYGATKLAIRRAMEGYPSIDKVLAEKDRGTHP
IMGFRVQKLWSPPYLQVALDLDNLDAMERIINDLPDKERVLIEAGTPLVKKFGVGVVGKIRELRPSAFIIADLKTLDVGR
VEIKMAADETADAVAISGLGTIESIKKAIHETQKQGIYSILDMMNVADFEEKLSALPDDLKPDIVLLHRNVDLETYKAEK
GEDTSEMTEWGNIKSIKKLIGDGLVAVAGGITPNKVEEATSKGADIIIAGRYIIGSRDVRRAAEDFLAHFPQDPDSMRLA
LDEDEQVN

Sequences:

>Translated_408_residues
MYNIGEALIGDGNELAHIDLIIGEKEGPVGQAFANGLSNLSVGHTPLTTVIRPNLMTKPATLIIPKVTVGDLDDAAKVFG
PAQTAVGRAVADAVEEGYIPKDIVEDIVINVSVFIDPAAKNYRKIYQYNYGATKLAIRRAMEGYPSIDKVLAEKDRGTHP
IMGFRVQKLWSPPYLQVALDLDNLDAMERIINDLPDKERVLIEAGTPLVKKFGVGVVGKIRELRPSAFIIADLKTLDVGR
VEIKMAADETADAVAISGLGTIESIKKAIHETQKQGIYSILDMMNVADFEEKLSALPDDLKPDIVLLHRNVDLETYKAEK
GEDTSEMTEWGNIKSIKKLIGDGLVAVAGGITPNKVEEATSKGADIIIAGRYIIGSRDVRRAAEDFLAHFPQDPDSMRLA
LDEDEQVN
>Mature_408_residues
MYNIGEALIGDGNELAHIDLIIGEKEGPVGQAFANGLSNLSVGHTPLTTVIRPNLMTKPATLIIPKVTVGDLDDAAKVFG
PAQTAVGRAVADAVEEGYIPKDIVEDIVINVSVFIDPAAKNYRKIYQYNYGATKLAIRRAMEGYPSIDKVLAEKDRGTHP
IMGFRVQKLWSPPYLQVALDLDNLDAMERIINDLPDKERVLIEAGTPLVKKFGVGVVGKIRELRPSAFIIADLKTLDVGR
VEIKMAADETADAVAISGLGTIESIKKAIHETQKQGIYSILDMMNVADFEEKLSALPDDLKPDIVLLHRNVDLETYKAEK
GEDTSEMTEWGNIKSIKKLIGDGLVAVAGGITPNKVEEATSKGADIIIAGRYIIGSRDVRRAAEDFLAHFPQDPDSMRLA
LDEDEQVN

Specific function: Catalyzes the formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate [H]

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790006, Length=221, Percent_Identity=26.6968325791855, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR020868
- InterPro:   IPR014826
- InterPro:   IPR001754
- InterPro:   IPR020568
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF08714 Fae; PF00215 OMPdecase [H]

EC number: =4.1.2.43 [H]

Molecular weight: Translated: 44437; Mature: 44437

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNIGEALIGDGNELAHIDLIIGEKEGPVGQAFANGLSNLSVGHTPLTTVIRPNLMTKPA
CCCCCCHHCCCCCCEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCC
TLIIPKVTVGDLDDAAKVFGPAQTAVGRAVADAVEEGYIPKDIVEDIVINVSVFIDPAAK
EEEEECCEECCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCHH
NYRKIYQYNYGATKLAIRRAMEGYPSIDKVLAEKDRGTHPIMGFRVQKLWSPPYLQVALD
HHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEE
LDNLDAMERIINDLPDKERVLIEAGTPLVKKFGVGVVGKIRELRPSAFIIADLKTLDVGR
CCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCHHHHHHHCCCCEEEEEECEEECCCE
VEIKMAADETADAVAISGLGTIESIKKAIHETQKQGIYSILDMMNVADFEEKLSALPDDL
EEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KPDIVLLHRNVDLETYKAEKGEDTSEMTEWGNIKSIKKLIGDGLVAVAGGITPNKVEEAT
CCCEEEEEECCCCEEEECCCCCCHHHHHHCCCHHHHHHHHCCCCEEEECCCCHHHHHHHH
SKGADIIIAGRYIIGSRDVRRAAEDFLAHFPQDPDSMRLALDEDEQVN
CCCCCEEEECEEEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MYNIGEALIGDGNELAHIDLIIGEKEGPVGQAFANGLSNLSVGHTPLTTVIRPNLMTKPA
CCCCCCHHCCCCCCEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCC
TLIIPKVTVGDLDDAAKVFGPAQTAVGRAVADAVEEGYIPKDIVEDIVINVSVFIDPAAK
EEEEECCEECCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCHH
NYRKIYQYNYGATKLAIRRAMEGYPSIDKVLAEKDRGTHPIMGFRVQKLWSPPYLQVALD
HHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEE
LDNLDAMERIINDLPDKERVLIEAGTPLVKKFGVGVVGKIRELRPSAFIIADLKTLDVGR
CCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCHHHHHHHCCCCEEEEEECEEECCCE
VEIKMAADETADAVAISGLGTIESIKKAIHETQKQGIYSILDMMNVADFEEKLSALPDDL
EEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KPDIVLLHRNVDLETYKAEKGEDTSEMTEWGNIKSIKKLIGDGLVAVAGGITPNKVEEAT
CCCEEEEEECCCCEEEECCCCCCHHHHHHCCCHHHHHHHHCCCCEEEECCCCHHHHHHHH
SKGADIIIAGRYIIGSRDVRRAAEDFLAHFPQDPDSMRLALDEDEQVN
CCCCCEEEECEEEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]